Identificação de doença óssea renal em pacientes portadores de insuficiência renal crônica em hemodiálise por meio da avaliação laboratorial e métodos de imagem

Orientador: Rogério A. MulinariDissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências da SaúdeResumo: A doença óssea metabólica é uma das maiores causas de morbidade e mortalidade nos pacientes em hemodiálise. Foram estudados 30 pacientes portadores de insuficiência renal crônica em hemodiálise. Os pacientes foram divididos em 2 grupos: grupo 1 (n= 20) com dosagens da fração intacta do hormônio das paratireóides (PTHi) superiores a 4 vezes o limite superior do normal (72pg/ml) e grupo 2 (n= 10) com níveis séricos inferiores a este valor. Procedeu-se a análise comparativa com dosagens séricas de cálcio total, fósforo, fosfatase alcalina (FA) total, radiografias das mãos, crânio e ombros além de ultra-sonografia da região cervical para visualização das paratireóides. Não houve diferença entre os grupos quanto à distribuição de idade e sexo. O grupo 1 (M= 13, F= 7) apresentou idade média de 39,8 anos e o grupo 2 (M= 7, F= 3) de 45,5 anos (p= 0,1053). A presença de hiperparatireoidismo secundário (HS) traduzido por níveis elevados de PTHi se correlacionou com o tempo em diálise, r = 0,64 (n= 30). As dosagens do cálcio total, fosfatase alcalina total e fósforo não mostraram correlação com o PTHi em ambos grupos. A ultra-sonografia identificou aumento das paratireóides em 25% (5/20) dos pacientes do grupo 1. Entretanto, não alcançou diferença estatística contra o grupo 2, onde em nenhum paciente se evidenciou este achado. Por outro lado, ao menos uma alteração radio lógica foi observada em 14 pacientes do grupo 1 (70%) em contraste com 2 pacientes do grupo 2 (20%) (p< 0,05). Conclui-se existir uma forte associação entre o tempo de hemodiálise e gravidade de hiperparatireoidismo e que cálcio, fósforo e fosfatase alcalina total não foram parâmetros que se correlacionaram a presença de hiperparatireoidismo secundário (HS). Finalmente, as alterações radiográficas se encontraram mais presentes nos pacientes com HS severo ao contrário dos pacientes com outras formas de doença óssea.Abstract: The metabolic bone disease is one of the major causes of morbity and mortality in hemodialysis patients. Thirty patients were studied with end stage renal disease in hemodialysis. The patients were divided into two groups: group 1 (n= 20) had intact fraction of the parathyroid hormone (iPTH) four times the upper limit of normality (72pg/ml), and group 2 (n= 10) had serum levels lower than those. The study includes a comparative analysis of calcium, phosphorus, alkaline total phosphatase, hands, head and shoulders x- rays, and neck ultra-sound to visualize the parathyroid glands. We did not find differences in age and sex between the groups. The group 1 (M= 13, F= 7) had a mean age of 39.8 years and the group 2 (M== 7, F= 3) of 45.5 years (p= 0.1053). The presence of secondary hyperparathyroidism (SH) showed by elevated levels of iPTH was correlated to the time of dialysis, r= 0.64 (n= 30). The total calcium, alkaline phosphatase and phosphorus levels showed no correlation with the iPTH in either group. The ultrasound identified an increase in the parathyroids sizes in 25% (5/20) of the patients in group 1. However, it did not reach statistical differences when compared to group 2, in which no patient showed that evidence. On the other hand, at least one radiological alteration was observed in 14 patients in group 1 (70%) in contrast with 2 patients in group 2 (20%) (p<0.05). We conclude that a strong correlation exists between the time of hemodialysis and the severity of hyperparathyroidism and that calcium, phosphorus and total alkaline phosphatase were not correlated to the presence of SH. Finally, the radiographic alterations were more commonly found in patients with severe SH than in patients with other forms of bone disease

Thermodynamic and Kinetic Study of Lignocellulosic Waste Gasification

In this chapter, the kinetic behavior during the steam gasification of sawdust, plum, and olive pits was investigated by thermogravimetric analysis where the weight loss is measured with the temperature variation at different heating rates (5, 10, and 15 K/min). The weight loss and their derivative curves show that the gasification takes place in three visible stages. The kinetic study was carried out using Coats-Redfern methods. The Ginstling-Brounstein model showed better fit. The obtained activation energy values vary between 70 and 100 kJ/mol for the pyrolysis stage for all studied agro-industrial wastes. On the other hand, a thermodynamic model was proposed to predict the five waste gasification processes, considering the char and tar production. The proposed model allows it to perform a parametric study, analyzing the process variables’ effect on the exergetic efficiency. The higher temperatures favor the endothermic reactions as the H2 and CO formation reactions. Therefore, in the product, moles of H2 and CO increase and consequently the exergy efficiency of the process. Increasing the equivalence ratio value, H2, CO, and CH4 contents decrease; thus the calorific value of the produced gas and the exergetic efficiency decrease. In addition, the CO2 and H2O presences in the syngas composition diminish its calorific value and the exergetic efficiency. Considering the influence of supply steam/biomass ratio, the exergetic efficiency decreases with the growth of this parameter

Thermogravimetric and Kinetic Analysis of Different Agro-Industrial Wastes Under Nitrogen Atmosphere

In this work, the behavior during thermal treatment processes of marcs, stalk and peach pits, from the wineries, canning and the jam industries was studied.The immediate and elemental analysis are realized.The studied agro-industrial wastes have higher water content than 30%, suggesting that these wastes should be dried before the thermal treatment. The ash contents are smaller than 7%, considering these contents low.The ultimate analysis showed higher oxygen concentrations present in the studied agroindustrial wastes, decreasing the HHV. The trace elements contents in these wastes are determined too. These elements remain in the char/ash fraction of the different pyrolysis products, during thermal treatment under inert atmosphere. Thermal decomposition of the studied wastes was studied in inert nitrogen atmosphere. Their decompositions proceed through three stages of weight loss, dehydration, active pyrolysis and passive pyrolysis. The maximum weight loss took place during the active pyrolysis step. In this stage, the peach pits exhibit the most prominent due to the higher content of hemicellulose. Another reason can be the difference of elements concentrations such us the Ca. This element is present in smaller concentration in the peach pits.Themarcs decomposing at lower temperature compared with the other biomasses. It also has the lowest mass loss. This behavior might be associated with the highest content of extractives in its structure. The higher value of activation energy was obtained for the peach pits, meaning slower reaction. The reaction orders were smaller than 1 for the studied agro-industrial wastes.Fil: Echegaray, Marcelo Eduardo. Universidad Nacional de San Juan; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Saffe Pinto, María Alejandra. Universidad Nacional de San Juan; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Mazza, German Delfor. Universidad Nacional del Comahue; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rodriguez, Rosa Ana. Universidad Nacional de San Juan; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Mortuary practices in the wetland of the lower Paraná

En este trabajo, presentamos una síntesis de las prácticas mortuorias de los grupos aborígenes del tramo final de la cuenca del Plata, correspondiente al Holoceno tardío. Este registro ha sido analizado siguiendo dos aspectos centrales: la tendencia general de las conductas mortuorias y su variabilidad vinculada con las diferentes unidades del paisaje que conforman el área bajo estudio. Dicho análisis ha permitido observar como tendencia el uso de áreas formales de enterramiento, el empleo extendido de inhumaciones secundarias, la orientación de las inhumaciones primarias, preferentemente con un eje este-oeste, y un claro tratamiento mortuorio diferencial basado en el sexo y en la edad de los individuos en algunos sitios. Paralelamente, se observa un aumento en la cantidad de inhumaciones secundarias en los sectores del paisaje donde existe mayor fragmentación del mismo, particularmente en las islas del Delta inferior y superior.In this paper we present a synthesis of mortuary practices of aboriginal groups who inhabited the final stretch of the La Plata basin during the late Holocene. This record has been analyzed with regard to two central aspects: general tendencies of burial behaviors and their variability related to the geomorphological units of the landscape. The analysis has allowed us to identify the tendency to use formal disposal areas, an extended practice of secondary burials, a preference for East-West orientation of primary burials, and a clearly differentiated mortuary treatment based on sex and age of individuals. At the same time, an increased presence of secondary burials has been observed in units of the landscape where greater fragmentation exists, mainly in the higher and lower Delta islands.Fil: Mazza, Bárbara Pamela. Secretaría de Cultura de la Nación. Dirección Nacional de Cultura y Museos. Instituto Nacional de Antropología y Pensamiento Latinoamericano; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Loponte, Daniel Marcelo. Secretaría de Cultura de la Nación. Dirección Nacional de Cultura y Museos. Instituto Nacional de Antropología y Pensamiento Latinoamericano; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Exergy analyses of onion drying by convection: Influence of dryer parameters on performance

This research work is concerned in the exergy analysis of the continuous-convection drying of onion. The influence of temperature and air velocity was studied in terms of exergy parameters. The energy and exergy balances were carried out taking into account the onion drying chamber. Its behavior was analyzed based on exergy efficiency, exergy loss rate, exergetic improvement potential rate, and sustainability index. The exergy loss rates increase with the temperature and air velocity augmentation. Exergy loss rate is influenced by the drying air temperatures and velocities because the overall heat transfer coefficient varies with these operation conditions. On the other hand, the exergy efficiency increases with the air velocity augmentation. This behavior is due to the energy utilization was improved because the most amount of supplied energy was utilized for the moisture evaporation. However, the exergy efficiency decreases with the temperature augmentation due to the free moisture being lower, then, the moisture begins diffusing from the internal structure to the surface. The exergetic improvement potential rate values show that the exergy efficiency of onion drying process can be ameliorated. The sustainability index of the drying chamber varied from 1.9 to 5.1. To reduce the process environmental impact, the parameters must be modified in order to ameliorate the exergy efficiency of the process.Fil: Castro, María. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Ingeniería Química; ArgentinaFil: Román Barón, María Celia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Ingeniería Química; ArgentinaFil: Echegaray, Marcelo Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Ingeniería Química; ArgentinaFil: Mazza, German Delfor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas. Universidad Nacional del Comahue. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas; ArgentinaFil: Rodriguez, Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Ingeniería Química; Argentin

Prediction of the lignocellulosic winery wastes behavior during gasification process in fluidized bed: Experimental and theoretical study

This work presents studies about the gasification of the lignocellulosic winery wastes in fluidized bed to obtain energy. Based on the exergy analysis, the exergetic improvement potential (IP) and sustainability index (SI) variations with different operational variables were analyzed. IP increases and SI decreases when moisture content, ER and SBR augment. On the other hand, both indexes present contrary behavior with the temperature increasing. Additionally, the kinetic behavior was investigated using a macro thermo-balance. The thermal decomposition of the studied biomass wastes at three heating rate, 5, 10 and 15 °C/min under steam/air mixture atmosphere show that the gasification takes place in three visible stage: water vaporization, pyrolysis and the last step associated with the reaction of the char by CO 2 . The distributed activation energy model method (DAEM) was used. The decomposition is not a single reaction stage, it includes the contributions of parallel reaction steps on the global reaction rate. Last, the fluidization was analyzed using air at room temperature and local atmospheric pressure. Each experiment was carried out with 100% and 75% v lignocellulosic wastes. Segregation, slugging and channelization in all studied cases. However, the addition of sand particles improves the behavior of both winery wastes.Fil: Rodriguez, Rosa Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas. Universidad Nacional del Comahue. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas; ArgentinaFil: Mazza, German Delfor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas. Universidad Nacional del Comahue. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas; ArgentinaFil: Fernandez Brizuela, Anabel Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas. Universidad Nacional del Comahue. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas; ArgentinaFil: Saffe Pinto, María Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas. Universidad Nacional del Comahue. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas; ArgentinaFil: Echegaray, Marcelo Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas. Universidad Nacional del Comahue. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas; Argentin

New data for urn burials of Guarani archaeological sites in the southern extreme of La Plata basin

Entre los complejos comportamientos mortuorios que se observan en los sitios arqueológicos pertenecientes a la unidad arqueológica Guaraní, se registran las inhumaciones en urnas. Los estudios vinculados con el análisis de estas estructuras mortuorias tienen escasos antecedentes en la bibliografía académica en general, y particularmente para el extremo meridional de la cuenca del Plata. El objetivo de este trabajo, precisamente, es contribuir al mismo mediante el análisis de los elementos óseos incluidos en urnas mortuorias recuperadas en sitios guaraníes del Delta del Paraná (Argentina). Esta región constituye el punto más meridional de la expansión de estos grupos de origen amazónico, cuyo registro mortuorio posee un buen estado de conservación, a diferencia de lo que sucede en otras regiones donde se distribuye esta unidad arqueológica. En este trabajo analizamos los restos óseos recuperados en urnas funerarias de los sitios Arroyo Malo, Arroyo Fredes y Arroyo La Glorieta (Delta del Paraná), que fueron excavados a principios del siglo XX por diversos investigadores y que hoy forman parte de las colecciones museísticas del Museo de La Plata. Se estudió la composición sexual, etaria y anatómica de los conjuntos óseos, como así también una serie de variables tafonómicas. Los resultados muestran la preponderancia de individuos masculinos adultos, representados básicamente por huesos largos y elementos del cráneo, algunos de ellos con huellas de corte y pintura roja (ocre) en cantidades abundantes. Estos indicadores, junto a otros de origen tafonómico, señalan que las inhumaciones son secundarias, producto de la desarticulación, descarne y selección de determinadas unidades anatómicas.Many urn burials were recorded among the complex mortuary behaviors observed in archaeological sites belonging tothe Guaraní archaeological unit. Urn burial analyses are generally scarce and, particularly, in the southern point of La Plata basin. The objective of this work is to contribute to the Guaraní society’s knowledge by the analysis of human remains buried in urns from archaeological sites located in the Paraná Delta (Argentina). This region is the southern point of this Amazonian group’s expansion, whose mortuary remains are well preserved, in contrast to other Guarani´s regions. In this work, we analyze the human skeletal remains recovered from urn burials from three archaeological sites located in the Paraná Delta: Arroyo Malo, Arroyo Fredes y Arroyo La Glorieta. These sites were excavated at the beginning of the 20th century by many researchers and today are part of Museo de La Plata´s collections. We studied sexual composition, age and anatomical structure as well as a set of taphonomic variables. The results show the preponderance of male adult individuals, represented mainly by long bones and cranial elements, some of them with cut marks and red paint (ochre) in abundant quantities. These indicators, along with others of taphonomical origin, indicate the secondary treatment of the dead product of the disassembly, defleshing and selection of certain anatomical units.Fil: Mazza, Bárbara Pamela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Secretaría de Cultura de la Nación. Dirección Nacional de Cultura y Museos. Instituto Nacional de Antropología y Pensamiento Latinoamericano; ArgentinaFil: Acosta, Alejandro Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Secretaría de Cultura de la Nación. Dirección Nacional de Cultura y Museos. Instituto Nacional de Antropología y Pensamiento Latinoamericano; ArgentinaFil: Loponte, Daniel Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Secretaría de Cultura de la Nación. Dirección Nacional de Cultura y Museos. Instituto Nacional de Antropología y Pensamiento Latinoamericano; Argentin

BODY COMPOSITION IN CHRONIC KIDNEY DISEASE IN CONSERVATIVE TREATMENT

Introduction: Chronic Kidney Disease (CKD) is characterized by the presence of lesions in the renal parenchyma and progressive and irreversible loss of kidney function. Nutritional status is an important predictor of prognosis in CKD, including pre-dialysis phase, which underscores the importance of studies addressing the assessment of body composition in this population. Aim: To assess the body composition in CKD patients, and the association between phase angle and other nutritional parameters used in clinical practice. Methods: A prospective observational study conducted at the Clinic of Nephrology of the Federal University of Parana, between April and July of 2011. It included patients with CKD and the nutritional status was assessed by anthropometry, subjective global assessment (SGA) and bioelectrical impedance analysis. Results: A total of 32 patients were evaluated. There was significant and positive correlation between the phase angle and skeletal mass index (r=0.4541 e p=0.009; r=0,5064 e p=0,003). The phase angle was significantly lower in malnourished patients classified by SGA(p=0,01). There was a positive and significant correlation between the waist circumference and the C-reactive protein (r=0.4053 e p=0.0262). Conclusion: in this study, it was found, according to anthropometric measurements, patients with overweight, obesity and high body fat. The phase angle seems to identify body composition changes that precede changes of the anthropometric parameters. The SGA is a good tool for nutritional assessment in this population.Introdução: A Doença Renal Crônica (DRC) caracteriza-se pela presença de lesão no parênquima renal e perda progressiva e irreversível das funções do rim. O estado nutricional é um importante preditor de prognóstico na DRC, inclusive na fase pré-diálise, o que ressalta a importância de estudos direcionados a avaliação da composição corporal desta população. Objetivo: Verificar a composição corporal em pacientes com DRC em tratamento conservador; bem como a associação da medida do ângulo de fase, com outros parâmetros nutricionais utilizados na prática clínica. Métodos: Estudo prospectivo observacional realizado no Ambulatório de Nefrologia do Hospital de Clínicas da UFPR, entre os meses de abril a julho do ano de 2011. A amostra foi composta de indivíduos com diagnóstico de doença renal crônica (DRC). Foi realizada avaliação nutricional por meio de antropometria, avaliação subjetiva global (ASG) e bioimpedância elétrica (BIA). Resultados: Foram avaliados 32 pacientes. Verificou-se correlação significativa e positiva entre o AF com a %MLG e com IMME (r=0,4541 e p=0,009; r=0,5064 e p=0,003). O ângulo de fase foi significativamente menor em pacientes desnutridos classificados pela ASG (p=0,01). Verificou-se uma correlação positiva e significativa entre CA e PCR (r=0,4053 e p=0,0262). Conclusão: Nesta casuística, os dados antropométricos indicaram sobrepeso, obesidade e acúmulo de gordura corporal. O AF parece identificar alterações de composição corporal que antecedem alterações de parâmetros antropométricos. Pode-se verificar que a ASG pode ser uma ferramenta adequada na avaliação nutricional desta população.

A CFD comparative study of bubbling fluidized bed behavior with thermal effects using the open-source platforms mfix and openfoam

This work studies the performance of two open-source CFD codes, OpenFOAM and MFiX, to address bubbling fluidized bed system at different temperature and heat transfer conditions. Both codes are used to predict two parameters that are relevant for the design of fluidized units: the minimum fluidization velocity as a function of the temperature of the bed and wall-to-bed heat transfer coefficient from a lateral wall and from internal tubes. Although the CFD solvers are structuraly similar, there are some key differences (available models, meshing techniques, and balance formula-tions) that are often translated into differences in the fields prediction. The computational results are compared between both codes and against the experimental data. The minimum fluidization velocity can be correctly predicted with both codes at different temperatures while, in general, for the heat transfer and the fluidization patterns, MFiX shows slightly more accurate results compared to OpenFOAM but with low versatility for meshing curved geometries which might translate into higher computational costs for the same level of accuracy.Fil: Reyes Urrutia, Ramón Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas. Universidad Nacional del Comahue. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas; ArgentinaFil: Venier, César Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Centro de Investigaciones en Métodos Computacionales. Universidad Nacional del Litoral. Centro de Investigaciones en Métodos Computacionales; ArgentinaFil: Mariani, Nestor Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; ArgentinaFil: Nigro, Norberto Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Centro de Investigaciones en Métodos Computacionales. Universidad Nacional del Litoral. Centro de Investigaciones en Métodos Computacionales; ArgentinaFil: Rodriguez, Rosa Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas. Universidad Nacional del Comahue. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas; ArgentinaFil: Mazza, German Delfor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas. Universidad Nacional del Comahue. Instituto de Investigación y Desarrollo en Ingeniería de Procesos, Biotecnología y Energías Alternativas; Argentin

Evaluation of tissue response to periodontal dressings: histological study in tooth sockets of rats

Although the use of periodontal dressings is currently limited, there are some indications for their use. Selection of any material that will have direct contact with live tissues, such as periodontal dressings, should be careful in order to allow surgical wound healing. The aim of this study was to evaluate the intensity of inflammatory response and bone formation in tooth sockets of rats after implantation of three periodontal dressings. After removal of the right maxillary incisors of 84 male rats, each tooth socket received implantation of a polyethylene tube, 63 of which were filled with non-eugenol periodontal dressing and the remaining 21 tubes remained empty (control group). Histological evaluation assessed the intensity of inflammatory response and presence and location of bone tissue formation at postoperative periods of 7, 14 and 28 days. Statistical analysis was performed by the Kruskal-Wallis test at 5% significance level. Regarding the inflammatory infiltrate, at 28 days, there was statistically significant difference between one of periodontal dressings and control group (