Respuestas educativas para el alumnado de Educación Primaria con necesidades educativas especiales en la práctica del unihockey

El sistema educativo actual no da la suficiente importancia a las adaptaciones curriculares que determinados colectivos requieren. Esto ocurre generalmente en todas las áreas, pero más en concreto dentro de la Educación Física. Por este motivo, el presente trabajo trata de la propuesta de una Unidad Didáctica, en la que el punto de mira está relacionado con la práctica de un determinado deporte, en concreto, Unihockey o floorball, adaptado para determinados colectivos que necesiten sus correspondientes adaptaciones, pero con los mismos derechos al juego.Grado en Educación Primari

The Influence of Urban Environments on Oxidative Stress Balance: A Case Study on the House Sparrow in the Iberian Peninsula

The House Sparrow is a globally distributed species and is closely associated with anthropised environments. They are well-adapted to urban life; therefore the decline of their populations in Europe represents an unexpected event that demands an investigation into its causes. Causes that have promoted this decline are not well-known, but one of the highlighted hypotheses is an increase of oxidative stress linked to the toxicity of pollution in urban areas. From an ecophysiological perspective, oxidative damage, antioxidant defense, and oxidative balance are considered reliable indicators of environmental stressors such as pollutants. To carry out this study, blood samples were collected from House Sparrows in three different habitats that varied in terms of urbanization degree: urban, suburban, and rural; during the winter and breeding season. According to our results, urban sparrows showed higher levels of oxidative damage and higher activity of antioxidant enzymes, but lower antioxidant capacity in comparison with the rural birds; and these differences especially increase during the breeding season. The maintenance of oxidative balance increases in an urban environment in comparison to a rural one; we suggest that the high level of pollution and the poor quality diet linked to urban environments. The breeding season is expected to be particularly challenging for the oxidative balance of urban birds, when the reallocation of resources between self-maintenance and reproduction may be critical due to the scarcity of antioxidants found in urban areas. This study may contribute to determining the causes of the population decrease of House Sparrows in cities

Increased expression of cystine/glutamate antiporter in multiple sclerosis

<p>Abstract</p> <p>Background</p> <p>Glutamate excitotoxicity contributes to oligodendrocyte and tissue damage in multiple sclerosis (MS). Intriguingly, glutamate level in plasma and cerebrospinal fluid of MS patients is elevated, a feature which may be related to the pathophysiology of this disease. In addition to glutamate transporters, levels of extracellular glutamate are controlled by cystine/glutamate antiporter x_c^-, an exchanger that provides intracellular cystine for production of glutathione, the major cellular antioxidant. The objective of this study was to analyze the role of the system x_c^-in glutamate homeostasis alterations in MS pathology.</p> <p>Methods</p> <p>Primary cultures of human monocytes and the cell line U-937 were used to investigate the mechanism of glutamate release. Expression of cystine glutamate exchanger (xCT) was quantified by quantitative PCR, Western blot, flow cytometry and immunohistochemistry in monocytes in vitro, in animals with experimental autoimmune encephalomyelitis (EAE), the animal model of MS, and in samples of MS patients.</p> <p>Results and discussion</p> <p>We show here that human activated monocytes release glutamate through cystine/glutamate antiporter x_c^-and that the expression of the catalytic subunit xCT is upregulated as a consequence of monocyte activation. In addition, xCT expression is also increased in EAE and in the disease proper. In the later, high expression of xCT occurs both in the central nervous system (CNS) and in peripheral blood cells. In particular, cells from monocyte-macrophage-microglia lineage have higher xCT expression in MS and in EAE, indicating that immune activation upregulates xCT levels, which may result in higher glutamate release and contribution to excitotoxic damage to oligodendrocytes.</p> <p>Conclusions</p> <p>Together, these results reveal that increased expression of the cystine/glutamate antiporter system x_c^-in MS provides a link between inflammation and excitotoxicity in demyelinating diseases.</p

Los corticoides epidurales en el tratamiento del síndrome del canal lumbar estrecho

Se presenta una serie de 67 pacientes diagnosticados de síndrome del canal lumbar estrecho, tratados todos ellos con infíltraciones epidurales de corticosteroides, asociadas a un programa de rehabilitación realizado a continuación de las inyecciones. Tras el análisis de los datos se ha observado un porcentaje de buenos resultados cercano al 80%. Asimismo, el estudio ha puesto en evidencia la influencia clara del factor rehabilitación en la calidad del resultado final de los pacientes.The authors present a study on 67 patients with degenerative lumbar spinal stenosis. The treatment consisted in epidural injections with corticosteroids and a program of physical therapy. There was 80% of good results. A clear influence of the physical therapy program on the quality of the final result, has been proved

Los corticoides epidurales en el tratamiento de la hernia discal

Se presenta una serie de 233 pacientes diagnosticados de hernia discal lumbar y tratados mediante infiltraciones epidurales de corticoides, asociadas a un programa de rehabilitación realizado a continuación de las inyecciones. Los resultados con dicho tratamiento fueron satisfactorios en un 75% de los casos. Se observó una mejor evolución en pacientes varones, en pacientes cuya profesión conlleva esfuerzo físico, en hernias discales L5-S1, y en aquellos que han seguido un programa de rehabilitación tras las infiltraciones.An study on 233 patients with lumbar disc herniation, treated by means of epidural injections of steroids, added to a physical therapy programme is presented. The results obtained were fully satisfactory in 75% of the cases. Better results were observed in male patients, in patients subject to heavy physical activity in their laboral life, in disc herniations at L5-S1 level, and finally in those patients following a physical therapy programme after injections

SHARDS: constraints on the dust attenuation law of star-forming galaxies at z∼2

We make use of the Survey of High-z Absorption Red and Dead Sources, an ultradeep (<26.5AB) galaxy survey that provides optical photospectra at resolution R similar to 50, via medium-band filters (FWHM similar to 150 angstrom). This data set is combined with ancillary optical and NIR fluxes to constrain the dust attenuation law in the rest-frame NUV region of star-forming galaxies within the redshift window 1.5 < z < 3. We focus on the NUV bump strength (B) and the total-to-selective extinction ratio (R-V), targeting a sample of 1753 galaxies. By comparing the data with a set of population synthesis models coupled to a parametric dust attenuation law, we constrain R-V and B, as well as the colour excess, E(B - V). We find a correlation between R-V and B, which can be interpreted either as a result of the grain size distribution, or a variation of the dust geometry among galaxies. According to the former, small dust grains are associated with a stronger NUV bump. The latter would lead to a range of clumpiness in the distribution of dust within the interstellar medium of star-forming galaxies. The observed wide range of NUV bump strengths can lead to a systematic in the interpretation of the UV slope beta typically used to characterize the dust content. In this study, we quantify these variations, concluding that the effects are Delta beta similar to 0.4

Pilagá- Dependencia

El propósito de este proyecto radica en implementar SIU-Pilagá en dependencias de la Universidad Nacional de Córdoba.Fil: Gelatti, Sonia Andrea. Universidad Nacional de Córdoba. Secretaría de Planificación y Gestión Institucional. Dirección General de Tecnologías Informáticas; Argentina.Fil: Goye Pampliega, Maximiliano. Universidad Nacional de Córdoba. Secretaría de Planificación y Gestión Institucional. Dirección General de Tecnologías Informáticas; Argentina.Fil: Durand Pauli, Graciela. Universidad Nacional de Córdoba. Secretaría de Planificación y Gestión Institucional. Dirección General de Programación Presupuestaria; Argentina.Fil: Ensabella, Carla María. Universidad Nacional de Córdoba. Secretaría de Planificación y Gestión Institucional. Dirección General de Contabilidad y Finanzas; Argentina.Fil: Aveta, Amelia. Universidad Nacional de Córdoba. Secretaría de Planificación y Gestión Institucional. Dirección General de Contabilidad y Finanzas; Argentina.Fil: Marek, Marta Susana. Universidad Nacional de Córdoba. Secretaría de Planificación y Gestión Institucional. Dirección General de Contrataciones; Argentina.Fil: Montoya, Juan Antonio. Universidad Nacional de Córdoba. Secretaría de Planificación y Gestión Institucional. Dirección General de Tecnologías Informáticas; Argentina

Virtual meeting, real and sound science: report of the 17 th Meeting of the Spanish Society for Developmental Biology (SEBD-2020)

The Spanish Society for Developmental Biology (SEBD) organized its 17th meeting in November 2020 (herein referred to as SEBD2020).This meeting, originally programmed to take place in the city of Bilbao, was forced onto an online format due to the SARS-CoV2, COVID-19 pandemic. Although, we missed the live personal interactions and missed out on the Bilbao social scene, we were able to meet online to pres- ent our work and discuss our latest results. An overview of the activities that took place around the meeting, the different scientific sessions and the speakers involved are presented here. The pros and cons of virtual meetings are discussed

Epidemiological trends of HIV/HCV coinfection in Spain, 2015-2019

Altres ajuts: Spanish AIDS Research Network; European Funding for Regional Development (FEDER).Objectives: We assessed the prevalence of anti-hepatitis C virus (HCV) antibodies and active HCV infection (HCV-RNA-positive) in people living with HIV (PLWH) in Spain in 2019 and compared the results with those of four similar studies performed during 2015-2018. Methods: The study was performed in 41 centres. Sample size was estimated for an accuracy of 1%. Patients were selected by random sampling with proportional allocation. Results: The reference population comprised 41 973 PLWH, and the sample size was 1325. HCV serostatus was known in 1316 PLWH (99.3%), of whom 376 (28.6%) were HCV antibody (Ab)-positive (78.7% were prior injection drug users); 29 were HCV-RNA-positive (2.2%). Of the 29 HCV-RNA-positive PLWH, infection was chronic in 24, it was acute/recent in one, and it was of unknown duration in four. Cirrhosis was present in 71 (5.4%) PLWH overall, three (10.3%) HCV-RNA-positive patients and 68 (23.4%) of those who cleared HCV after anti-HCV therapy (p = 0.04). The prevalence of anti-HCV antibodies decreased steadily from 37.7% in 2015 to 28.6% in 2019 (p < 0.001); the prevalence of active HCV infection decreased from 22.1% in 2015 to 2.2% in 2019 (p < 0.001). Uptake of anti-HCV treatment increased from 53.9% in 2015 to 95.0% in 2019 (p < 0.001). Conclusions: In Spain, the prevalence of active HCV infection among PLWH at the end of 2019 was 2.2%, i.e. 90.0% lower than in 2015. Increased exposure to DAAs was probably the main reason for this sharp reduction. Despite the high coverage of treatment with direct-acting antiviral agents, HCV-related cirrhosis remains significant in this population