External root morphology of maxillary first premolars in Kenyan Africans

Objective: To determine the external root morphology of the maxillary first premolarsin Kenyan Africans.Design: In vitro descriptive cross-sectional study.Setting: School of Dental Sciences, University of Nairobi.Subjects: One hundred and fifty five extracted maxillary first premolar teeth obtainedfrom patients aged between 13-30 years attending dental clinics within Nairobi.Main outcome measures: Number of roots, direction of root curvature and toothlength.Results: A total of 155 maxillary first premolars were studied, 77 from males and 78from females. Overall, there were 83.2% two-rooted teeth (mean tooth length: buccalroot 22.3 mm; lingual root 21.2 mm), 10.3% one-rooted (mean tooth length-22.6 mm)and 6.5% three-rooted. Three roots occurred more commonly in males than femalesand this was a statistically significant gender difference (P<0.05). Males were foundto have larger mean tooth length than females in multirooted teeth. Majority of theroots were straight (57.2%). Distal and “S” curvatures were the commonest (19.1% and10.2% respectively). There were no significant gender differences in direction of rootcurvature (P>0.05).Conclusions: Maxillary first premolars were mostly two-rooted with straight roots.Males presented with two or three roots more often than females and had significantlylarger mean tooth lengths

Effect of Pastor’s Church Ministry on their Family Stability in Nairobi County, Kenya

The family is an important place for individual mental growth. Pastors’ families, however, experience ministry related challenges with potential ramifications on their family stability. The specific objectives were; To find out the extent to which pastors work as a preacher affects family stability in selected churches in Eastlands – Nairobi County, to establish the extent to which pastoral care work affects family stability, and to determine the extent to which church administration work affects family stability. The research was guided by the Structural Family Theory developed by Salvador Minuchin and Family Systems theory propounded by Murray Bowen. Descriptive survey design was used. The sample of 166 respondents comprised of pastors, pastors’ spouses and adult children. Data were collected using a structured questionnaire and analyzed using descriptive statistical techniques. Hypotheses were tested using Spearman’s rank correlation technique at p<.05. The results showed that the relationship between preaching and family stability was not statistically significant. However, it was found that church administration and pastoral care had a significant negative correlation with family stability. It was recommended that the church needs to find ways of mitigating negative effects of church ministry by professionalizing its human resource systems and engaging professional counsellors for pastors and their families

UTILIZATION OF VISUAL AND REALIA INSTRUCTIONAL MATERIALS IN ENHANCING ACQUISITION OF PRE-READING SKILLS AMONG PRESCHOOL LEARNERS IN NAROK COUNTY, KENYA

Early childhood education, also referred to as preschool education is essential to children’s social, physical, emotional, and cognitive growth. Learning can be made more effective when the teachers have the right instructional materials. The study was guided by the following research questions: how were visual instructional materials utilized in teaching pre-reading skills among preschool children? and how were realia instructional materials utilized in the teaching of pre-reading skills among preschool learners? The study adopted a descriptive survey design and data was collected using questionnaires, interviews, and observation schedules. The findings of the study revealed that visual instructional materials for teaching pre-reading skills were available but not adequate in most of the schools, hence affecting the effective teaching of pre-reading skills among the learners. The study further established that most preschools lacked adequate realia materials for teaching pre-reading skills. It was concluded that Preschool teachers should attend relevant workshops, seminars, vocational and teacher professional development courses, to acquire pedagogical skills, besides effective utilization of Visual and Realia instructional materials in teaching pre-reading skills to preschool learners. Emphasis should be on pedagogical content knowledge.  Article visualizations

Computational Analysis of Some Enzymes Involved in Synthesis of Secondary Metabolites in Camellia Sinensis

Tea is one of the most popular beverages worldwide, native to Southeast Asia but currently cultivated in over 35 countries. Studies on its chemical composition reveal that polyphenol metabolites account for 25% to 35% of the total dry weight. Tea has many health benefits owing to secondary metabolites whose level of expression in various tea clones determine tea flavor. The flavor (taste and aroma) and the color of processed tea are used to assess its quality and therefore a detailed analysis of key enzymes involved in the synthesis of secondary metabolites is necessary.  Enzyme PAL (phenylalanine ammonia-lyase) a key enzyme in the phenylpropanoid pathway, playing an important role in the plant development and defense. C4H (cinnamte-4-hydroxylse) an important enzyme in allocating significant amounts of carbon from phenylalanine into the biosynthesis of several metabolites, It maintains activities of the metabolic flux for the operation of the flavanoid pathway. 4CL (4-coumarate: COA ligase) the last enzyme in the general phenylpropanoid pathway that provides precursors for the biosynthesis of a large variety of plant natural products like COA thiol esters of 4-coumarate and other hydroxycinnamate. FLS (flavonol synthase) a key enzyme in flavonol synthesisthat determines the final content of flavonols which play an important role in defense related functions and as potent antioxidants. ANS (anthocyanidin synthase) an enzyme in the biosynthetic pathway to anthocyanin. This study employed a computational approach in the analysis of some of these enzymes to gain insight into the mechanism of synthesis of these bioactive secondary metabolites. Biological databases were used to retrieve amino acid sequences of these key enzymes. Consensus conserved regions in these sequences were identified from highly identical homologs which were useful in modeling the enzymes' three dimensional structures.  A total of 5 key enzymes were analyzed and pockets and cavities in their structures; hence the putative substrate binding sites determined, which gave insight into the enzymes-substrate as well as enzyme cofactor interactions. The preferred orientations of the interactions between substrates and/or co-factors with the enzymes were also simulated through molecular docking.  Analysis of these enzymes revealed unique enzyme structures and very specific substrate and co-factor preference. This analysis offers a platform for optimization of selective expression of these key enzymes through gene expression assays that can potentially alter the quality yield of tea clones. Keywords: camellia sinensis, Secondary metabolites, Conserved regions, Pockets and cavities, Molecular dockin

Mainstreaming emergency contraception in developing countries: A toolkit for policymakers and service providers

In late 2006, the Kenyan Ministry of Health (MOH), the Population Council, and Population Services International (PSI) launched an initiative to mainstream emergency contraception (EC) in Kenya. The initiative included a core set of activities aimed at improving overall awareness of EC across the country and strengthening the quality of EC services in both the public and private sectors. It was intended to serve as a model for other countries interested in improving access to EC, and to generate in-depth knowledge on EC program strategies and utilization characteristics in sub-Saharan Africa. The MOH drew lessons and experiences from the initiative to substantially revise the EC component of the 2010 National Family Planning Guidelines for Health Providers. This toolkit on mainstreaming emergency contraception in developing countries has been developed in response to one of the objectives of the 2006 initiative that sought to generate lessons that could serve as a model for other countries interested in improving access to EC, and to generate in-depth knowledge on EC program strategies and utilization characteristics in sub-Saharan Africa

Exploration of gender norms and socialization among early adolescents : the use of qualitative methods for the global early adolescent study

Purpose: The Global Early Adolescent Study (GEAS) was launched in 2014 with the primary goal of understanding the factors in early adolescence that predispose young people to subsequent sexual risks, and conversely, those that promote healthy sexuality across different cultural contexts. The present article describes the methodology that was used for the first phase of GEAS, which consisted of conducting qualitative research to understand the gendered transitions into adolescence and the role that gender norms play within the key relationships of adolescents. Researchers from each of the sites that had completed data collection were also elicited for their feedback on the key strengths, challenges, and lessons learned from conducting research among 11- to 14-year-old adolescents. The purpose of this article is to present the description of each of the methods that were used in GEAS, as well as the researchers' perspectives of using the methods among early adolescents in their sites. Methods: The GEAS is being implemented through a collaboration of university and nongovernmental institutions from 15 cities: Assiut (Egypt) Baltimore (U.S.), Blantyre (Malawi), Cape Town (South Africa), Cochabomba (Bolivia), Cuenca (Ecuador), Edinburgh (Scotland), Ghent (Belgium), Hanoi (Vietnam), Ile-Ife (Nigeria), Kinshasa (DRC), Nairobi (Kenya), New Delhi (India), Ouaga-dougou (Burkina Faso), and Shanghai (China). Approximately 30 in-depth interviews among adolescents and 30 in-depth interviews with their parent/guardian were conducted at each site, with adults and adolescents interviewed separately. To build trust and increase engagement among the adolescent participants, we used two different visual research methods: (1) timeline exercise which was small group based and (2) the Venn diagram exercise which was conducted individually and used at the start of the in-depth interview. Results: The visual aspects of both the timeline and the Venn diagrams not only helped to produce data for the purposes of the study, but also were a successful way of engaging the adolescent participants across sites. While the narrative interviews produced extremely rich data, researchers did notice that there were a few challenges among the younger adolescents. Challenges were related to the length of the interview, comprehension of questions, as some of the questions were either too abstract or asked adolescents about an experience they had not yet had and therefore could not address or articulate. Conclusions: Conducting the first phase of GEAS revealed important insights for research with participants who are in this developmental phase of early adolescence. Methods that involve greater engagement and those that are visual were shown to work well irrespective of the cultural setting

Policy brief—Mainstreaming emergency contraception in developing countries: A toolkit for policymakers and service providers

Kenyan Ministry of Health (MOH), the Population Council, and Population Services International (PSI) launched an initiative to mainstream emergency contraception (EC) in Kenya. The specific objectives of the initiative were to: increase knowledge, awareness, and use of EC among Kenyan women; increase knowledge and awareness of EC among health providers; and strengthen EC provision in both the private and public sectors. This policy brief describes a toolkit designed for policymakers and service providers which draws on the achievements, lessons learned, and experiences from this project

Hysteresis of Backflow Imprinted in Collimated Jets

We report two different types of backflow from jets by performing 2D special relativistic hydrodynamical simulations. One is anti-parallel and quasi-straight to the main jet (quasi-straight backflow), and the other is bent path of the backflow (bent backflow). We find that the former appears when the head advance speed is comparable to or higher than the local sound speed at the hotspot while the latter appears when the head advance speed is slower than the sound speed bat the hotspot. Bent backflow collides with the unshocked jet and laterally squeezes the jet. At the same time, a pair of new oblique shocks are formed at the tip of the jet and new bent fast backflows are generated via these oblique shocks. The hysteresis of backflow collisions is thus imprinted in the jet as a node and anti-node structure. This process also promotes broadening of the jet cross sectional area and it also causes a decrease in the head advance velocity. This hydrodynamic process may be tested by observations of compact young jets.Comment: 9 pages, 5 figures, accepted for publication in ApJ

Confirmed Sighting of a Spawning Aggregation of the Brown-marbled Grouper, Epinephelus fuscoguttatus, in Kenya

The occurrence of spawning aggregations at fixed sites and times is well documented for several species of reef fish. These aggregations are known to attract fishers and such species may therefore be vulnerable to overfishing. This is particularly true in the case of groupers which have intrinsically vulnerable life history traits. The brown-marbled grouper, Epinephelus fuscoguttatus, distributed throughout the Indo-Pacific region and classified by IUCN as Near Threatened, is reported to form spawning aggregations but little is known about its spawning behaviour; in the Western Indian Ocean this has only been reported for the Seychelles. This study confirmed spawning aggregation behaviour in E. fuscoguttatus in Kenya based on underwater observations and fishers’ knowledge of the phenomenon. We showed that E. fuscoguttatus forms short aggregations for ~5 days linked to the new moon for a 3-4 month period during the northeast monsoon (austral summer).  The numbers of aggregating fish appear to be low, however, and the species is currently not managed in Kenya. Considering the fact that only small areas of the Kenyan coastline are under total protection (8.6% of the country’s coral reefs), these factors suggest that there is an urgent need for additional management of E. fuscoguttatus if it is to survive in Kenya

Mixed QCD and weak corrections to top quark pair production at hadron colliders

The order $\alpha_s^2 \alpha$ mixed QCD and weak corrections to top quark pair production by quark antiquark annihilation are computed, keeping the full dependence on the $t$ and $\bar t$ spins. We determine the contributions to the cross section and to single and double top spin asymmetries at the parton level. These results are necessary ingredients for precise standard model predictions of top quark observables, in particular of top spin-induced parity-violating angular correlations and asymmetries at hadron colliders.Comment: 12 pages, 9 figure