The Ursinus Weekly, April 20, 1967

Artist team opens show • Meistersingers tour, sweep New England • College Bowl contest welcomes UC team • Students, faculty combine efforts • Betsy Miller wins Miss Mont. Co. title • Showboat on Delaware, juniors sponsor voyage • Genuine carnival concludes Campus Chest activities • Editorial • Endless policy changes harass concessionaires • Letters to the editor • Fuse complicates Happening; Audience reactions electric • Students devote time to retarded children • UC coeds cop curfew change constitutionally • Losing\u27s too easy for tennis team • Girls\u27 softball win features long ball • Shuman leads baseball team to three early season wins • Trackmen shatter Marks, edge Swarthmore, 72-68 • Netmen outclassed in lopsided defeat • Girls\u27 tennis team suffers double loss • Youthful Crossettes outhustle Penn, 8-1 • Greek gleanings • Campus best-sellershttps://digitalcommons.ursinus.edu/weekly/1200/thumbnail.jp

The Ursinus Weekly, March 7, 1966

Senior Symposium tours Phila. settlement homes • Curtain Club lists Spring dramatics • The Ballet Chaffee to be Wednesday evening Forum • Folk Society donates $250 • Y to present Accion leader • Swann receives memorial scholarship • Temple begins math internship • Editorial: The apathetic syndrome • Young and old, rich and poor accepted by Admissions Office: 81% of present freshmen placed near top of class • Dolman stresses importance of Admissions interviews • Letter to the editor • Swim team soaks Temple; Drops one to E. S\u27burg • Girls B\u27ball team drops game to WC • Intramural corner • Bears make creditable showing in MACs • 1965-1966 wrestling roundup • Greek gleanings • Players parody modern lifehttps://digitalcommons.ursinus.edu/weekly/1219/thumbnail.jp

Identification of Neural Outgrowth Genes using Genome-Wide RNAi

While genetic screens have identified many genes essential for neurite outgrowth, they have been limited in their ability to identify neural genes that also have earlier critical roles in the gastrula, or neural genes for which maternally contributed RNA compensates for gene mutations in the zygote. To address this, we developed methods to screen the Drosophila genome using RNA-interference (RNAi) on primary neural cells and present the results of the first full-genome RNAi screen in neurons. We used live-cell imaging and quantitative image analysis to characterize the morphological phenotypes of fluorescently labelled primary neurons and glia in response to RNAi-mediated gene knockdown. From the full genome screen, we focused our analysis on 104 evolutionarily conserved genes that when downregulated by RNAi, have morphological defects such as reduced axon extension, excessive branching, loss of fasciculation, and blebbing. To assist in the phenotypic analysis of the large data sets, we generated image analysis algorithms that could assess the statistical significance of the mutant phenotypes. The algorithms were essential for the analysis of the thousands of images generated by the screening process and will become a valuable tool for future genome-wide screens in primary neurons. Our analysis revealed unexpected, essential roles in neurite outgrowth for genes representing a wide range of functional categories including signalling molecules, enzymes, channels, receptors, and cytoskeletal proteins. We also found that genes known to be involved in protein and vesicle trafficking showed similar RNAi phenotypes. We confirmed phenotypes of the protein trafficking genes Sec61alpha and Ran GTPase using Drosophila embryo and mouse embryonic cerebral cortical neurons, respectively. Collectively, our results showed that RNAi phenotypes in primary neural culture can parallel in vivo phenotypes, and the screening technique can be used to identify many new genes that have important functions in the nervous system

Pandemic as Opportunity

The COVID-19 pandemic presented the Kennesaw State University Library System with the question, " How can the library maintain live face-to-face reference services in a manner that is safe for all involved ?" Challenges to creating a live virtual reference desk that arose included the need to serve two campuses simultaneously, librarians working from home, and using conferencing technology in unexplored ways. The resulting Virtual In-Person (VIP) Reference service was the answer to our immediate situation, yet lessons were learned for future opportunities to push our services beyond the traditional

Pandemic as Opportunity: Creating and Implementing a Live Virtual Reference Desk

The COVID-19 pandemic presented the Kennesaw State University Library System with the question, How can the library maintain live face-to-face reference services in a manner that is safe for all involved ? Challenges to creating a live virtual reference desk that arose included the need to serve two campuses simultaneously, librarians working from home, and using conferencing technology in unexplored ways. The resulting Virtual In-Person (VIP) Reference service was the answer to our immediate situation, yet lessons were learned for future opportunities to push our services beyond the traditional

Measuring changes in groupworking skills in undergraduate students after employer involvement in group skill development

Examined changes in students' group skills before and after employer feedback and in students receiving and not receiving feedback, and the relationship between skill level and performance on the assignment. Experience with employer-observed group work increased students' self-rating of their skills; teams with a good knowledge of team processes obtained high marks, but did not rate themselves more highl

The Association Between Health Problems and Driver Status Among Older Adults

Many health problems, especially those associated with older age, can have an impact on an individual’s mobility. This paper addresses how specific functional limitations and medical conditions may be associated with driving status, while controlling for age and gender. This paper uses baseline data (N=2025) from a longitudinal survey of adults, ages 55 and older, the Study of Physical Performance and Age-Related Changes in Sonomans (SPPARCS). For the 35 selected medical conditions and functional limitations, this report presents the prevalence, the relative “risk” ratio (i.e., the risk that an individual with that condition no longer drives), and the attributable risk (i.e., the percent of ex-drivers with each condition). Compared to current drivers, ex-drivers had higher rates of physical limitations (ability to ascend one flight of stairs or walk three blocks), cognitive impairment, vision problems and stroke. The conditions with the highest relative risk included personal mobility limitations (such as the ability to transfer onto or from bed and the ability to use the lavatory) and decreased peripheral vision. The relative risks of medical conditions’ effects on driving status offer a perspective on individuals’ mobility choices, and the attributable risks offer a perspective on the most important causes of driving cessation in the elderly population