um-Topology in multi-normed vector lattices

Let be a separating family of lattice seminorms on a vector lattice X, then is called a multi-normed vector lattice (or MNVL). We write if for all . A net in an MNVL is said to be unbounded m-convergent (or um-convergent) to x if for all . um-Convergence generalizes un-convergence (Deng et al. in Positivity 21:963–974, 2017; Kandić et al. in J Math Anal Appl 451:259–279, 2017) and uaw-convergence (Zabeti in Positivity, 2017. doi: 10.1007/s11117-017-0524-7 ), and specializes up-convergence (Aydın et al. in Unbounded p-convergence in lattice-normed vector lattices. arXiv:1609.05301 ) and -convergence (Dabboorasad et al. in -Convergence in locally solid vector lattices. arXiv:1706.02006v3 ). um-Convergence is always topological, whose

Design of a trial-based economic evaluation on the cost-effectiveness of employability interventions among work disabled employees or employees at risk of work disability: The CASE-study

<p>Abstract</p> <p>Background</p> <p>In the Netherlands, absenteeism and reduced productivity due to work disability lead to high yearly costs reaching almost 5% of the gross national product. To reduce the economic burden of sick leave and reduced productivity, different employability interventions for work-disabled employees or employees at risk of work disability have been developed. Within this study, called 'CASE-study' (Cost-effectiveness Analysis of Sustainable Employability), five different employability interventions directed at work disabled employees with divergent health complaints will be analysed on their effectiveness and cost-effectiveness. This paper describes a consistent and transparent methodological design to do so.</p> <p>Methods/design</p> <p>Per employability intervention 142 participants are needed whereof approximately 66 participants receiving the intervention will be compared with 66 participants receiving usual care. Based on the intervention-specific characteristics, a randomized control trial or a quasi-experiment with match-criteria will be conducted. Notwithstanding the study design, eligible participants will be employees aged 18 to 63, working at least 12 h per week, and at risk of work disability, or already work-disabled due to medical restrictions. The primary outcome will be the duration of sick leave. Secondary outcomes are health status and quality of life. Outcomes will be assessed at baseline and then 6, 12 and 18 months later. Economic costs will consist of healthcare costs and cost of lost production due to work disability, and will be evaluated from a societal perspective.</p> <p>Discussion</p> <p>The CASE-study is the first to conduct economic evaluations of multiple different employability interventions based on a similar methodological framework. The cost-effectiveness results for every employability intervention will be published in 2014, but the methods, strengths and weaknesses of the study protocol are discussed in this paper. To contribute to treatment options in occupational health practice and enable the development of guidelines on how to conduct economic evaluation better suited to this field; this paper provides an important first step.</p> <p>Trial registration</p> <p>Four trials involved in the CASE-study are registered with the Netherlands Trial Registry: Care for Work (<a href="http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2040">NTR2886</a>), Health and Motion (<a href="http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2040">NTR3111</a>), Guidance to Excel in Return to Work (<a href="http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2040">NTR3151</a>), Care for Companies/Second Care (<a href="http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2040">NTR3136</a>).</p

Clinical Application of Ultra-High-Frequency Ultrasound

Musculoskeletal ultrasound involves the study of many superficial targets, especially in the hands, wrists, and feet. Many of these areas are within the first 3 cm of the skin surface and are ideal targets for ultra-high-frequency ultrasound. The high spatial resolution and the superb image quality achievable allow foreseeing a wider use of this novel technique, which has the potential to bring innovation to diagnostic imaging

High-dimensional simplexes for supermetric search

In a metric space, triangle inequality implies that, for any three objects, a triangle with edge lengths corresponding to their pairwise distances can be formed. The n-point property is a generalisation of this where, for any (n+1) objects in the space, there exists an n-dimensional simplex whose edge lengths correspond to the distances among the objects. In general, metric spaces do not have this property; however in 1953, Blumenthal showed that any semi-metric space which is isometrically embeddable in a Hilbert space also has the n-point property. We have previously called such spaces supermetric spaces, and have shown that many metric spaces are also supermetric, including Euclidean, Cosine, Jensen-Shannon and Triangular spaces of any dimension. Here we show how such simplexes can be constructed from only their edge lengths, and we show how the geometry of the simplexes can be used to determine lower and upper bounds on unknown distances within the original space. By increasing the number of dimensions, these bounds converge to the true distance. Finally we show that for any Hilbert-embeddable space, it is possible to construct Euclidean spaces of arbitrary dimensions, from which these lower and upper bounds of the original space can be determined. These spaces may be much cheaper to query than the original. For similarity search, the engineering tradeoffs are good: we show significant reductions in data size and metric cost with little loss of accuracy, leading to a significant overall improvement in exact search performance

Desenvolvimento de estrutura de Kartcross

A estrutura de um kartcross é um dos elementos com maior importância neste tipo de veículos, pois para além de agregar e suportar os restantes componentes, é o componente que permite a proteção do ocupante do veículo. Nesta tese foi concebida uma estrutura para um veículo kartcross, de acordo com o regulamento da Federação Internacional do Automóvel (FIA). Foram tidos em consideração os principais requisitos regulamentares para o desenvolvimento de uma estrutura homologável. Foi efetuado um estudo de simulação estrutural por elementos finitos, para avaliar o seu desempenho mecânico e verificar se a estrutura cumpre com os requisitos de segurança, em particular a célula de sobrevivência, de acordo com as condições definidas no regulamento da FIA. Foi também efetuado um estudo simplificado de otimização estrutural com vista a melhorar o seu desempenho no que respeita à resistência e à rigidez à torção.The structure of a kartcross is one of the most important elements in this type of vehicle, because besides adding and supporting the other components, it is the component that allows the protection of the occupant of the vehicle. In this thesis a structure for a kartcross vehicle was conceived, according to the regulation of the International Automobile Federation (FIA). The main regulatory requirements for the development of an approvable have been taken into account. A finite element structural simulation study was carried out to assess its mechanical performance and to verify that it meets the safety conditions of the survival cell according to the conditions defined in the FIA regulation. A simplified structural optimization study has also been carried out to improve its performance, in particular with regard to strength and torsional stiffness.