Ground state of the random-bond spin-1 Heisenberg chain

Stochastic series expansion quantum Monte Carlo is used to study the ground state of the antiferromagnetic spin-1 Heisenberg chain with bond disorder. Typical spin- and string-correlations functions behave in accordance with real-space renormalization group predictions for the random-singlet phase. The average string-correlation function decays algebraically with an exponent of -0.378(6), in very good agreement with the prediction of $-(3-\sqrt{5})/2\simeq -0.382$, while the average spin-correlation function is found to decay with an exponent of about -1, quite different from the expected value of -2. By implementing the concept of directed loops for the spin-1 chain we show that autocorrelation times can be reduced by up to two orders of magnitude.Comment: 9 pages, 10 figure

Disorder Induced Phase Transition in a Random Quantum Antiferromagnet

A two-dimensional Heisenberg model with random antiferromagnetic nearest-neighbor exchange is studied using quantum Monte Carlo techniques. As the strength of the randomness is increased, the system undergoes a transition from an antiferromagnetically ordered ground state to a gapless disordered state. The finite-size scaling of the staggered structure factor and susceptibility is consistent with a dynamic exponent $z = 2$.Comment: Revtex 3.0, 10 pages + 5 postscript figures available upon request, UCSBTH-94-1

Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia

We previously demonstrated prolonged, profound CD4+ T-lymphopenia in rheumatoid arthritis (RA) patients following lymphocyte-depleting therapy. Poor reconstitution could result either from reduced de novo T-cell production through the thymus or from poor peripheral expansion of residual T-cells. Interleukin-7 (IL-7) is known to stimulate the thymus to produce new T-cells and to allow circulating mature T-cells to expand, thereby playing a critical role in T-cell homeostasis. In the present study we demonstrated reduced levels of circulating IL-7 in a cross-section of RA patients. IL-7 production by bone marrow stromal cell cultures was also compromised in RA. To investigate whether such an IL-7 deficiency could account for the prolonged lymphopenia observed in RA following therapeutic lymphodepletion, we compared RA patients and patients with solid cancers treated with high-dose chemotherapy and autologous progenitor cell rescue. Chemotherapy rendered all patients similarly lymphopenic, but this was sustained in RA patients at 12 months, as compared with the reconstitution that occurred in cancer patients by 3–4 months. Both cohorts produced naïve T-cells containing T-cell receptor excision circles. The main distinguishing feature between the groups was a failure to expand peripheral T-cells in RA, particularly memory cells during the first 3 months after treatment. Most importantly, there was no increase in serum IL-7 levels in RA, as compared with a fourfold rise in non-RA control individuals at the time of lymphopenia. Our data therefore suggest that RA patients are relatively IL-7 deficient and that this deficiency is likely to be an important contributing factor to poor early T-cell reconstitution in RA following therapeutic lymphodepletion. Furthermore, in RA patients with stable, well controlled disease, IL-7 levels were positively correlated with the T-cell receptor excision circle content of CD4+ T-cells, demonstrating a direct effect of IL-7 on thymic activity in this cohort

Deep Inelastic Scattering from off-Shell Nucleons

We derive the general structure of the hadronic tensor required to describe deep-inelastic scattering from an off-shell nucleon within a covariant formalism. Of the large number of possible off-shell structure functions we find that only three contribute in the Bjorken limit. In our approach the usual ambiguities encountered when discussing problems related to off-shellness in deep-inelastic scattering are not present. The formulation therefore provides a clear framework within which one can discuss the various approximations and assumptions which have been used in earlier work. As examples, we investigate scattering from the deuteron, nuclear matter and dressed nucleons. The results of the full calculation are compared with those where various aspects of the off-shell structure are neglected, as well as with those of the convolution model.Comment: 36 pages RevTeX, 9 figures (available upon request), ADP-93-210/T128, PSI-PR-93-13, accepted for publication in Physical Review

Dose Finding Study To Assess Safety, Pk And Efficacy Of Fimepinostat (Cudc‐907) With Venetoclax Or Rituximab Plus Bendamustine In Patients With Relapsed/Refractory Lymphoma

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/149554/1/hon9_2632.pd

Sensitivity of deexcitation energies of superdeformed secondary minima to the density dependence of symmetry energy with the relativistic mean-field theory

The relationship between deexcitation energies of superdeformed secondary minima relative to ground states and the density dependence of the symmetry energy is investigated for heavy nuclei using the relativistic mean field (RMF) model. It is shown that the deexcitation energies of superdeformed secondary minima are sensitive to differences in the symmetry energy that are mimicked by the isoscalar-isovector coupling included in the model. With deliberate investigations on a few Hg isotopes that have data of deexcitation energies, we find that the description for the deexcitation energies can be improved due to the softening of the symmetry energy. Further, we have investigated deexcitation energies of odd-odd heavy nuclei that are nearly independent of pairing correlations, and have discussed the possible extraction of the constraint on the density dependence of the symmetry energy with the measurement of deexcitation energies of these nuclei.Comment: 14 pages, 3 figure

Q2Q^2--Dependence of the Gerasimov-Drell-Hearn Sum Rule

We test the Gerasimov-Drell-Hearn (GDH) sum rule numerically by calculating the total photon absorption cross sections $\sigma_{1/2}$ and $\sigma_{3/2}$ on the nucleon via photon excitation of baryon resonances in the constituent quark model. A total of seventeen, low-lying, non-strange baryon resonances are included in this calculation. The transverse and longitudinal interference cross section, $\sigma_{1/2}^{TL}$, is found to play an important role in the study of the $Q^2$ variation of the sum rule. The results show that the GDH sum rule is saturated by these resonances at a confidence level of 94%. In particular, the $P_{33}(1232)$ excitation largely saturates the sum rule at $Q^2 = 0$, and dominates at small $Q^2$. The GDH integral has a strong $Q^2$-dependence below $Q^2= 1.0 {GeV}^2$ and changes its sign around $Q^2= 0.3 {GeV}^2$. It becomes weakly $Q^2$-dependent for $Q^2 > 1.0 {GeV}^2$ because of the quick decline of the resonance contributions. We point out that the $Q^2$ variation of the GDH sum rule is very important for understanding the nucleon spin structure in the non-perturbative QCD region.Comment: revtex, 17 pages, 3 ps figs include

Backward pion-nucleon scattering

A global analysis of the world data on differential cross sections and polarization asymmetries of backward pion-nucleon scattering for invariant collision energies above 3 GeV is performed in a Regge model. Including the $N_\alpha$, $N_\gamma$, $\Delta_\delta$ and $\Delta_\beta$ trajectories, we reproduce both angular distributions and polarization data for small values of the Mandelstam variable $u$, in contrast to previous analyses. The model amplitude is used to obtain evidence for baryon resonances with mass below 3 GeV. Our analysis suggests a $G_{39}$ resonance with a mass of 2.83 GeV as member of the $\Delta_{\beta}$ trajectory from the corresponding Chew-Frautschi plot.Comment: 12 pages, 16 figure

Euclidean Structure from N>=2 Parallel Circles: Theory and Algorithms

International audienceOur problem is that of recovering, in one view, the 2D Euclidean structure, induced by the projections of N parallel circles. This structure is a prerequisite for camera calibration and pose computation. Until now, no general method has been described for N > 2. The main contribution of this work is to state the problem in terms of a system of linear equations to solve.We give a closed-form solution as well as bundle adjustment-like refinements, increasing the technical applicability and numerical stability. Our theoretical approach generalizes and extends all those described in existing works for N = 2 in several respects, as we can treat simultaneously pairs of orthogonal lines and pairs of circles within a unified framework. The proposed algorithm may be easily implemented, using well-known numerical algorithms. Its performance is illustrated by simulations and experiments with real images