970 research outputs found

    Developing and Promoting a Nuclear Security Curriculum at Amity University, India: Beginnings, Successes and Challenges

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    Amity University is one of India’s leading research- and innovation-driven private universities. The Amity Institute of Nuclear Science and Technology (AINST), established in 2009, contribute to Amity’s mission to promote national development through philanthropy, education and research. Very recently, courses related to nuclear security and security culture have been added to the existing AINST curriculum. The purpose of introducing this course was to enhance the understanding of technical, policy, and regulatory challenges associated with nuclear security and to create a nuclear security culture among relevant local institutions. This paper describes the process involved in establishing nuclear security as an elective course in the Engineering and Technology Domain for undergraduate-level and postgraduate-level engineering students at the Institute, discusses both challenges faced in these early stages as well as achievements and successes, and outlines future plans for the program

    Realtime IRIS Recognition & Authentication System

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    Many organizations are using different kinds of automated person's identification systems which improve the user's need, satisfaction and efficiency to secure resource. The information depends on the recent developments in person's identification using Biometric technology method. By using this technology we are to ensure to identify a person weather he/she is real person or fake person. The aim is to increase the security of biometric reorganization frameworks, by adding liveness assessment in a fast, user friendly and non-intrusive manner. In this first, a user must be enroll in the system so that his biometric template can be captured. This template is securely stored in a database. This template is retrieved when an individual needs to be identified. Biometric refers to automatic identification of a person based on his/her physiological or behavioral characteristics. This offers several advantages over traditional methods involving ID cards or PIN. To implement this we are using MATLAB

    A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

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    Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is largely based on genome-wide association studies (GWAS) analysis of common SNPs. Leveraging phased haplotypes from the 1000 Genomes Project, we report a GWAS meta-analysis of 185 thousand CAD cases and controls, interrogating 6.7 million common (MAF>0.05) as well as 2.7 million low frequency (0.005<MAF<0.05) variants. In addition to confirmation of most known CAD loci, we identified 10 novel loci, eight additive and two recessive, that contain candidate genes that newly implicate biological processes in vessel walls. We observed intra-locus allelic heterogeneity but little evidence of low frequency variants with larger effects and no evidence of synthetic association. Our analysis provides a comprehensive survey of the fine genetic architecture of CAD showing that genetic susceptibility to this common disease is largely determined by common SNPs of small effect siz

    A Case Study of Amul: Implementation of Extension Strategy to Repositioning Brand During Covid-19 Period

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    During lockdown and consequent pandemic, many organizations reduced their production, and few shut their operations. Some organizations continued their regular production. Apart from Pharma, very few organizations raised their production and raised their sales. Amul, a dairy products company is the one which in addition to raising production and sales, established an emotional and social connection with their clients. The advantage of essential commodity category and milk production aided its success during the pandemic. In this paper, the marketing strategy of Amul is review as backbone of their success being the advertising strategy

    DETERMINATION OF FACTORS CONTRIBUTING TOWARDS CIRCULAR ECONOMY: AN EMPIRICAL EVIDENCE OF HOMEMAKERS – NON WORKING FEMALES.

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    Purpose- This paper highlighted the significance of various factors influencing the contribution of home economists or simply the homemakers (non working females) towards the ‘Circular Economy’. The study was based on the empirical study conducted in Meerut City in western UP, India. Design/Methodology/Approach- The paper employed the exploratory research design in the initial stage for identifying the influencing factors/variables and furthermore descriptive research design was used to analyse the primary data. The sample unit was the housewives/house makers (non working females) of Meerut City with sample size of 250 (valid responses). Tabulation, Cross Tabulation &amp; Descriptive Statistics were utilized to describe the data and ‘Correlation and Regression techniques’ were used for compiling the results. Findings- The findings ascertained that mostly house makers were in the age bracket of 26-35 years, post graduates with an income level of Rs. 40000/- pm who were significantly contributing towards ‘Circular Economy’. This contribution had positive relationship with various relevant factors, out of which most significant were ‘Resource saving initiatives’, ‘Avoiding Unnecessary use of Social Media’ and Recycling of the Products’. Practical Implication- The study was highly practical being ‘Circular Economy’ had been the most sought transformation in recent times and every social unit was responsible for the same. Homemakers were the key managers in terms of managing the whole house and they required more visibility and transparency for their fruitful efforts towards economy of the nation. Originality/Value- The study was highly valuable because the entire world had been stepping towards the circular economy and the paper was original as it was based on primary data obtained from 250 (valid responses) of housewives of Meerut City

    Reprogramming energy metabolism and inducing angiogenesis : co-expression of monocarboxylate transporters with VEGF family members in cervical adenocarcinomas

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    Background: Deregulation of cellular energetic metabolism was recently pointed out as a hallmark of cancer cells. This deregulation involves a metabolic reprogramming that leads to a high production of lactate. Lactate efflux, besides contributing for the glycolytic flux, also acts in the extracellular matrix, contributing for cancer malignancy, by, among other effects, induction of angiogenesis. However, studies on the interplay between cancer metabolism and angiogenesis are scarce. Therefore, the aim of the present study was to evaluate the metabolic and vascular molecular profiles of cervical adenocarcinomas, their co-expression, and their relation to the clinical and pathological behavior. Methods: The immunohistochemical expression of metabolism-related proteins (MCT1, MCT4, CD147, GLUT1 and CAIX) as well as VEGF family members (VEGF-A, VEGF-C, VEGF-D, VEGFR-1, VEGFR-2 and VEGFR-3) was assessed in a series of 232 cervical adenocarcinomas. The co-expression among proteins was assessed and the expression profiles were associated with patients’ clinicopathological parameters. Results: Among the metabolism-related proteins, MCT4 and CAIX were the most frequently expressed in cervical adenocarcinomas while CD147 was the less frequently expressed protein. Overall, VEGF family members showed a strong and extended expression with VEGF-C and VEGFR-2 as the most frequently expressed and VEGFR-1 as the less expressed member. Co-expression of MCT isoforms with VEGF family members was demonstrated. Finally, MCT4 was associated with parametrial invasion and HPV18 infection, CD147 and GLUT1 with distant metastasis, CAIX with tumor size and HPV18 infection, and VEGFR-1 with local and lymphnode metastasis. Conclusions: The results herein presented provide additional evidence for a crosstalk between deregulating cellular energetics and inducing angiogenesis. Also, the metabolic remodeling and angiogenic switch are relevant to cancer progression and aggressiveness in adenocarcinomas.CP received a post-doctoral fellowship (SFRH/BPD/69479/2010) and FM-S received a doctoral fellowship (SFRH/BD/87139/2012) from FCT (Portuguese Foundation for Science and Technology). This work was supported by the FCT grant ref. PTDC/SAU-FCF/104347/2008, under the scope of "Programa Operacional Tematico Factores de Competitividade" (COMPETE) of "Quadro Comunitario de Apoio III" and co-financed by Fundo Comunitario Europeu FEDER, and also by FAPESP 2008/03232-1

    Activity in perceptual classification networks as a basis for human subjective time perception

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    Despite being a fundamental dimension of experience, how the human brain generates the perception of time remains unknown. Here, we provide a novel explanation for how human time perception might be accomplished, based on non-temporal perceptual classification processes. To demonstrate this proposal, we build an artificial neural system centred on a feed-forward image classification network, functionally similar to human visual processing. In this system, input videos of natural scenes drive changes in network activation, and accumulation of salient changes in activation are used to estimate duration. Estimates produced by this system match human reports made about the same videos, replicating key qualitative biases, including differentiating between scenes of walking around a busy city or sitting in a cafe or office. Our approach provides a working model of duration perception from stimulus to estimation and presents a new direction for examining the foundations of this central aspect of human experience

    Valgus extension overload syndrome of the elbow in a test cricket fast bowler

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    No Abstract South African Journal of Sports Medicine Vol. 20 (4) 2008: pp. 119-12

    Synaptic AMPA receptor composition in development, plasticity and disease

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    Exploring synergies and trade-offs among the sustainable development goals: collective action and adaptive capacity in marginal mountainous areas of India

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    Global environmental change (GEC) threatens to undermine the sustainable development goals (SDGs). Smallholders in marginal mountainous areas (MMA) are particularly vulnerable due to precarious livelihoods in challenging environments. Acting collectively can enable and constrain the ability of smallholders to adapt to GEC. The objectives of this paper are: (i) identify collective actions in four MMA of the central Indian Himalaya Region, each with differing institutional contexts; (ii) assess the adaptive capacity of each village by measuring livelihood capital assets, diversity, and sustainable land management practices. Engaging with adaptive capacity and collective action literatures, we identify three broad approaches to adaptive capacity relating to the SDGs: natural hazard mitigation (SDG 13), social vulnerability (SDG 1, 2 and 5), and social–ecological resilience (SDG 15). We then develop a conceptual framework to understand the institutional context and identify SDG synergies and trade-offs. Adopting a mixed method approach, we analyse the relationships between collective action and the adaptive capacity of each village, the sites where apparent trade-offs and synergies among SDGs occur. Results illustrate each village has unique socio-environmental characteristics, implying distinct development challenges, vulnerabilities and adaptive capacities exist. Subsequently, specific SDG synergies and trade-offs occur even within MMA, and it is therefore crucial that institutions facilitate locally appropriate collective actions in order to achieve the SDGs. We suggest that co-production in the identification, prioritisation and potential solutions to the distinct challenges facing MMA can increase understandings of the specific dynamics and feedbacks necessary to achieve the SDGs in the context of GEC
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