4,197 research outputs found
Note about a second "evidence" for a WIMP annual modulation
This note, with its five questions, is intended to contribute to a
clarification about a claimed "evidence" by the DAMA group of an annual
modulation of the counting rate of a Dark Matter NaI(Tl) detector as due to a
neutralino (SUSY-LSP) Dark Matter candidate.Comment: LaTex, 3 pages, 2 figure
On Quantum Algorithms
Quantum computers use the quantum interference of different computational
paths to enhance correct outcomes and suppress erroneous outcomes of
computations. In effect, they follow the same logical paradigm as
(multi-particle) interferometers. We show how most known quantum algorithms,
including quantum algorithms for factorising and counting, may be cast in this
manner. Quantum searching is described as inducing a desired relative phase
between two eigenvectors to yield constructive interference on the sought
elements and destructive interference on the remaining terms.Comment: 15 pages, 8 figure
Price v. State: the Price is Not Right—Maryland’s Showcase Showdown with Inconsistent Criminal Jury Verdicts
Efficient discrete-time simulations of continuous-time quantum query algorithms
The continuous-time query model is a variant of the discrete query model in
which queries can be interleaved with known operations (called "driving
operations") continuously in time. Interesting algorithms have been discovered
in this model, such as an algorithm for evaluating nand trees more efficiently
than any classical algorithm. Subsequent work has shown that there also exists
an efficient algorithm for nand trees in the discrete query model; however,
there is no efficient conversion known for continuous-time query algorithms for
arbitrary problems.
We show that any quantum algorithm in the continuous-time query model whose
total query time is T can be simulated by a quantum algorithm in the discrete
query model that makes O[T log(T) / log(log(T))] queries. This is the first
upper bound that is independent of the driving operations (i.e., it holds even
if the norm of the driving Hamiltonian is very large). A corollary is that any
lower bound of T queries for a problem in the discrete-time query model
immediately carries over to a lower bound of \Omega[T log(log(T))/log (T)] in
the continuous-time query model.Comment: 12 pages, 6 fig
Bifidobacteria and lactobacilli in the gut microbiome of children with non-alcoholic fatty liver disease: which strains act as health players?
Introduction: Non-alcoholic fatty liver disease (NAFLD), considered the leading cause of chronic liver disease in children, can often progress from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH). It is clear that obesity is one of the main risk factors involved in NAFLD pathogenesis, even if specific mechanisms have yet to be elucidated. We investigated the distribution of intestinal bifidobacteria and lactobacilli in the stools of four groups of children: obese, obese with NAFL, obese with NASH, and healthy, age-matched controls (CTRLs). Material and methods: Sixty-one obese, NAFL and NASH children and 54 CTRLs were enrolled in the study. Anthropometric and metabolic parameters were measured for all subjects. All children with suspected NASH underwent liver biopsy. Bifidobacteria and lactobacilli were analysed in children’s faecal samples, during a broader, 16S rRNA-based pyrosequencing analysis of the gut microbiome. Results: Three Bifidobacterium spp. (Bifidobacterium longum, Bifidobacterium bifidum, and Bifidobacterium adolescentis) and five Lactobacillus spp. (L. zeae, L. vaginalis, L. brevis, L. ruminis, and L. mucosae) frequently recurred in metagenomic analyses. Lactobacillus spp. increased in NAFL, NASH, or obese children compared to CTRLs. Particularly, L. mucosae was significantly higher in obese (p = 0.02426), NAFLD (p = 0.01313) and NASH (p = 0.01079) than in CTRLs. In contrast, Bifidobacterium spp. were more abundant in CTRLs, suggesting a protective and beneficial role of these microorganisms against the aforementioned diseases. Conclusions: Bifidobacteria seem to have a protective role against the development of NAFLD and obesity, highlighting their possible use in developing novel, targeted and effective probiotics
Drosophila Importin-α2 Is Involved in Synapse, Axon and Muscle Development
Nuclear import is required for communication between the cytoplasm and the nucleus and to enact lasting changes in gene transcription following stimuli. Binding to an Importin-α molecule in the cytoplasm is often required to mediate nuclear entry of a signaling protein. As multiple isoforms of Importin-α exist, some may be responsible for the entry of distinct cargoes rather than general nuclear import. Indeed, in neuronal systems, Importin-α isoforms can mediate very specific processes such as axonal tiling and communication of an injury signal. To study nuclear import during development, we examined the expression and function of Importin-α2 in Drosophila melanogaster. We found that Importin-α2 was expressed in the nervous system where it was required for normal active zone density at the NMJ and axonal commissure formation in the central nervous system. Other aspects of synaptic morphology at the NMJ and the localization of other synaptic markers appeared normal in importin-α2 mutants. Importin-α2 also functioned in development of the body wall musculature. Mutants in importin-α2 exhibited errors in muscle patterning and organization that could be alleviated by restoring muscle expression of Importin-α2. Thus, Importin-α2 is needed for some processes in the development of both the nervous system and the larval musculature
Future large-scale water-Cherenkov detector
MEMPHYS (MEgaton Mass PHYSics) is a proposed large-scale water-Cherenkov
experiment to be performed deep underground. It is dedicated to nucleon decay
searches and the detection of neutrinos from supernovae, solar, and atmospheric
neutrinos, as well as neutrinos from a future beam to measure the CP violating
phase in the leptonic sector and the mass hierarchy. This paper provides an
overview of the latest studies on the expected performance of MEMPHYS in view
of detailed estimates of its physics reach, mainly concerning neutrino beams
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