PENGARUH ORGANIZATIONAL CLIMATE DAN JOB INVOLVEMENT TERHADAP ORGANIZATIONAL CITIZENSHIP BEHAVIOR PADA PT. OSEANO ADHITAPRASARANA KOTA BANDUNG

ABSTRAK Penelitian ini berawal dari terjadinya keterlambatan finalisasi kinerja karyawan pada PT. Oseano Adhitaprasarana. Tujuan dari penelitian ini adalah untuk mengetahui dan menganalisis pengaruh organizational climate, dan job involvement terhadap organizational citizenship behavior karyawan pada PT. Oseano Adhitaprasarana Kota Bandung. Penelitian ini menggunakan teknik sampel non probabilitas, sampel dalam penelitian ini berjumlah 58 responden kepada karyawan PT. Oseano Adhitaprasarana. Skala yang digunakan adalah skala Likert dengan instrument penelitian berupa kuesioner. Penelitian ini menggunakan metode deskriptif dan verifikatif. Hasil penelitian ini menunjukan bahwa organizational climate pada PT. Oseano Adhitaprasarna Kota Bandung secara keseluruhan termasuk pada kategori kurang baik, kemudian job involvement pada PT. Oseano Adhitaprasarana Kota Bandung secara keseluruhan termasuk pada kategori kurang baik, dan organizational citizenship behavior pada PT. Oseano Adhitaprasarana Kota Bandung secara keseluruhan termasuk pada kategori kurang baik. Organizational climate dan job involvement secara simultan dan parsial. Secara parsial berpengaruh signifikan terhadap organizational citizenship behavior. Secara simultan pengaruhnya sebesar 57,3 % dan sisanya 42,7 % dipengaruhi oleh variabel lain. Sedangkan secara parsial pengaruh organizational climate sebesar 22,3%, pengaruh job involvement sebesar 35,0%. Kata Kunci: Organizational Climate, Job Involvement dan Organizational Citizenship Behavio

A unified approach to molecular epidemiology investigations: tools and patterns in California as a case study for endemic shigellosis

<p>Abstract</p> <p>Background</p> <p>Shigellosis causes diarrheal disease in humans from both developed and developing countries, and multi-drug resistance is an emerging problem. The objective of this study is to present a unified approach that can be used to characterize endemic and outbreak patterns of shigellosis using use a suite of epidemiologic and molecular techniques. The approach is applied to a California case study example of endemic shigellosis at the population level.</p> <p>Methods</p> <p>Epidemiologic patterns were evaluated with respect to demographics, multi-drug resistance, antimicrobial resistance genes, plasmid profiles, and pulsed-field gel electrophoresis (PFGE) fingerprints for the 43 <it>Shigella </it>isolates obtained by the Monterey region health departments over the two year period from 2004-2005.</p> <p>Results</p> <p>The traditional epidemiologic as well as molecular epidemiologic findings were consistent with endemic as compared to outbreak shigellosis in this population. A steady low level of cases was observed throughout the study period and high diversity was observed among strains. In contrast to most studies in developed countries, the predominant species was <it>Shigella flexneri </it>(51%) followed closely by <it>S. sonnei </it>(49%). Over 95% of <it>Shigella </it>isolates were fully resistant to three or more antimicrobial drug subclasses, and 38% of isolates were resistant to five or more subclasses. More than half of <it>Shigella </it>strains tested carried the <it>tetB</it>, <it>catA</it>, or <it>bla</it>_TEMgenes for antimicrobial resistance to tetracycline, chloramphenicol, and ampicillin, respectively.</p> <p>Conclusion</p> <p>This study shows how epidemiologic patterns at the host and bacterial population levels can be used to investigate endemic as compared to outbreak patterns of shigellosis in a community. Information gathered as part of such investigations will be instrumental in identifying emerging antimicrobial resistance, for developing treatment guidelines appropriate for that community, and to provide baseline data with which to compare outbreak strains in the future.</p

A systematic review of psychosocial interventions for family carers of palliative care patients

<p>Abstract</p> <p>Background</p> <p>Being a family carer to a patient nearing the end of their life is a challenging and confronting experience. Studies show that caregiving can have negative consequences on the health of family carers including fatigue, sleep problems, depression, anxiety and burnout. One of the goals of palliative care is to provide psychosocial support to patients and families facing terminal illness. A systematic review of interventions for family carers of cancer and palliative care patients conducted at the start of this millennium demonstrated that there was a dearth of rigorous inquiry on this topic and consequently limited knowledge regarding the types of interventions likely to be effective in meeting the complex needs of family carers. We wanted to discern whether or not the evidence base to support family carers has improved. Furthermore, undertaking this review was acknowledged as one of the priorities for the International Palliative Care Family Carer Research Collaboration <url>http://www.centreforpallcare.org</url>.</p> <p>Methods</p> <p>A systematic review was undertaken in order to identify developments in family carer support that have occurred over the last decade. The focus of the review was on interventions that targeted improvements in the psychosocial support of family carers of palliative care patients. Studies were graded to assess their quality.</p> <p>Results</p> <p>A total of fourteen studies met the inclusion criteria. The focus of interventions included psycho-education, psychosocial support, carer coping, symptom management, sleep promotion and family meetings. Five studies were randomised controlled trials, three of which met the criteria for the highest quality evidence. There were two prospective studies, five pre-test/post-test projects and two qualitative studies.</p> <p>Conclusions</p> <p>The systematic review identified a slight increase in the quality and quantity of psychosocial interventions conducted for family carers in the last decade. More rigorous intervention research is required in order to meet the supportive care needs of family carers of palliative care patients.</p

Characterisation of Clostridium difficile Hospital Ward–Based Transmission Using Extensive Epidemiological Data and Molecular Typing

A population-based study in Oxfordshire (UK) hospitals by Sarah Walker and colleagues finds that in an endemic setting with good infection control, ward-based contact cannot account for most new cases of Clostridium difficile infection

Chimpanzee APOBEC3 proteins deter SIVs from any monkey business

Cross-species transmissions of viruses from animals to humans are at the origin of major human pathogenic viruses. While the role of ecological and epidemiological factors in the emergence of new pathogens is well documented, the importance of host factors is often unknown. Chimpanzees are the closest relatives of humans and the animal reservoir at the origin of the human AIDS pandemic. However, despite being regularly exposed to monkey lentiviruses through hunting, chimpanzees are naturally infected by only a single simian immunodeficiency virus, SIVcpz. Here, we asked why chimpanzees appear to be protected against the successful emergence of other SIVs. In particular, we investigated the role of the chimpanzee APOBEC3 genes in providing a barrier to infection by most monkey lentiviruses. We found that most SIV Vifs, including Vif from SIVwrc infecting western-red colobus, the chimpanzee's main monkey prey in West Africa, could not antagonize chimpanzee APOBEC3G. Moreover, chimpanzee APOBEC3D, as well as APOBEC3F and APOBEC3H, provided additional protection against SIV Vif antagonism. Consequently, lentiviral replication in primary chimpanzee CD4(+) T cells was dependent on the presence of a lentiviral vif gene that could antagonize chimpanzee APOBEC3s. Finally, by identifying and functionally characterizing several APOBEC3 gene polymorphisms in both common chimpanzees and bonobos, we found that these ape populations encode APOBEC3 proteins that are uniformly resistant to antagonism by monkey lentiviruses

Attending to warning signs of primary immunodeficiencies disease across the range of clinical practices

Purpose: Patients with primary immunodeficiency diseases (PIDD) may present with recurrent infections affecting different organs, organ-specific inflammation/autoimmunity, and also increased cancer risk, particularly hematopoietic malignancies. The diversity of PIDD and the wide age range over which these clinical occurrences become apparent often make the identification of patients difficult for physicians other than immunologists. The aim of this report is to develop a tool for educative programs targeted to specialists and applied by clinical immunologists. Methods: Considering the data from national surveys and clinical reports of experiences with specific PIDD patients, an evidence-based list of symptoms, signs, and corresponding laboratory tests were elaborated to help physicians other than immunologists look for PIDD. Results: Tables including main clinical manifestations, restricted immunological evaluation, and possible related diagnosis were organized for general practitioners and 5 specialties. Tables include information on specific warning signs of PIDD for pulmonologists, gastroenterologists, dermatologists, hematologists, and infectious disease specialists. Conclusions: This report provides clinical immunologists with an instrument they can use to introduce specialists in other areas of medicine to the warning signs of PIDD and increase early diagnosis. Educational programs should be developed attending the needs of each specialty.Fil: Costa Carvalho, Beatriz Tavares. Universidade Federal de São Paulo; BrasilFil: Sevciovic Grumach, Anete. Fundação ABC. Faculdade de Medicina; BrasilFil: Franco, José Luis. Universidad de Antioquia; ColombiaFil: Espinosa Rosales, Francisco Javier. Instituto Nacional de Pediatría. Unidad de Investigación en Inmunodeficiencias; MéxicoFil: Leiva, Lily E.. State University of Louisiana; Estados UnidosFil: King, Alejandra. Hospital de Niños Doctor Luis Calvo Mackenna. Unidad de Inmunología; ChileFil: Porras, Oscar. Hospital Nacional de Niños “Dr. Carlos Sáenz Herrera”; Costa RicaFil: Bezrodnik, Liliana. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Oleastro, Mathias. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; ArgentinaFil: Sorensen, Ricardo U.. State University of Louisiana; Estados Unidos. Universidad de La Frontera. Facultad de Medicina; MéxicoFil: Condino Neto, Antonio. Universidade de Sao Paulo; Brasi

PERENCANAAN STRATEGI TEKNOLOGI INFORMASI PADA M GROUP

PERENCANAAN STRATEGI TEKNOLOGI INFORMASI PADA M GROUP - M.Group Information technology,strategic plannin

ANALISIS PENGARUH WEBSITE QUALITY TERHADAP USER SATISFACTION DAN DAMPAKNYA TERHADAP INTENTION TO REVISIT PADA WEBSITE SMECDA.COM (STUDI KASUS WEBSITE KEMENTERIAN KOPERASI DAN UKM DEPUTI BIDANG PENGKAJIAN SUMBER DAYA UKMK)

ANALISIS PENGARUH WEBSITE QUALITY TERHADAP USER SATISFACTION DAN DAMPAKNYA TERHADAP INTENTION TO REVISIT PADA WEBSITE SMECDA.COM (STUDI KASUS WEBSITE KEMENTERIAN KOPERASI DAN UKM DEPUTI BIDANG PENGKAJIAN SUMBER DAYA UKMK)

Pengaruh Motivasi Kerja Dan Lingkungan Kerja Terhadap Kepuasan Kerja Karyawan (Studi Pada Pt. Pertani (Persero) Cabang Mojokerto Jl.Raden Wijaya No 6-10 Banjaragung Kec.Puri, Mojokerto Jawa Timur)

Penelitian ini bertujuan untuk menganalisis pengaruh dari variabel motivasi kerja dan lingkungan kerja terhadap kepuasan kerja karyawan di PT. Pertani (persero) Unit Mojokerjo. Penelitian ini adalah penelitian kuantitatif dengan jenis penelitian explanatory research, yaitu penelitian yang bertujuan untuk mengetahui hubungan antar variabel yang diteliti. Pengambilan sampel menggunakan teknik sensus dengan mengambil seluruh populasi sebagai sampel. Sampel yang didapatkan sebanyak 50 orang dari seluruh karyawan PT. Pertani (persero) Unit Mojokerjo. Proses pengumpulan data menggunakan kuesioner dengan jawaban yang diukur dengan skala likert, sedangkan analisis data menggunakan teknik analisis deskriptif dan analisis regresi linier berganda yang dibantu dengan program SPSS versi 23. Uji yang dilakukan untuk menguji instrumen penelitian adalah uji validitas, uji reliabilitas, dan uji asumsi klasik, sedangkan dalam analisis regresi linier berganda menggunakan uji f dan uji t. Hasil penelitian ini menunjukkan bahwa motivasi kerja dan lingkungan kerja berpengaruh positif dan signifikan baik secara parsial maupun secara simultan terhadap kepuasan kerja karyawan. Nilai koefisien korelasi (R2) sebesar 0,675 menunjukkan bahwa variabel motivasi kerja dan lingkungan kerja memiliki pengaruh sebesar 67,5% terhadap variabel kinerja karyawan. Sedangkan 32,5% sisanya dipengaruhi oleh variabel lain yang tidak dibahas dalam penelitian ini

Pengaruh Employer Branding Terhadap Turnover Intention Dengan Employee Engagement Sebagai Variabel Moderasi (Studi Pada Karyawan Divisi Marketing Pt. Xyz Cabang Surabaya)

Penelitian ini bertujuan untuk menjelaskan; 1) Pengaruh Employer Branding terhadap Employee Engagement PT. XYZ Cabang Surabaya, 2) Pengaruh Employer Branding terhadap Turnover Intention PT. XYZ Cabang Surabaya, 3) Pengaruh Employee Engagement terhadap Turnover Intention PT. XYZ Cabang Surabaya, 4) Pengaruh moderasi Employee Engagement memperkuat Employer Branding dan Turnover Intention PT. XYZ Cabang Surabaya. Penelitian ini merupakan jenis penelitian eksplanatori (explanatory research). Teknik pengumpulan data dalam penelitian ini menggunakan kuesioner dan dokumentasi. Populasi dalam penelitian ini berjumlah 50 karyawan. Teknik sampling yang digunakan adalah probability sampling dengan metode disproportionate random sampling. Sampel yang digunakan dalam penelitian ini berjumlah 44 orang dan dianalisis dengan teknik pengolahan data Partial Least Square (PLS) dengan menggunakan software SmartPLS versi 3.0. Metode pengumpulan data yang digunakan dalam penelitian ini adalah dengan menggunakan studi pendahuluan, studi literatur, dan survei lapangan. Skala yang digunakan dalam penelitian ini adalah skala likert. Hasil penelitian menunjukkan bahwa; (1) employer branding memiliki pengaruh positif dan signifikan terhadap employee engagement (2) employee engagement memiliki pengaruh yang negatif dan signifikan terhadap turnover intention (3) employer branding memiliki pengaruh langsung yang negatif dan signifikan terhadap turnover intention (4) employee engagement merupakan variabel yang memoderasi dan memperkuat antara employer branding dan turnover intention