Analisis Kepecayaan Konsumen Dan Risiko E-Commerce Terhadap Keputusan Pembelian Secara Elektronik (Survei Pada Komunitas Kaskus Regional Solo)

Proses pengambilan keputusan pembelian secara elektronik sangat berisiko bagi konsumen, oleh karena itu konsumen harus memperhatikan integritas penjual dan risiko-risiko yang akan ditanggung. Tujuan penelitian ini adalah untuk menganalisis apakah kepercayaan konsumen dan risiko e-commerce mempengaruhi konsumen dalam melakukan pembelian secara elektronik. Jenis penelitian ini menggunakan pendekatan deskriptif kuantitatif. Data yang digunakan dalam penelitian ini adalah data primer yang diperoleh dari kuesioner yang disebarkan pada komunitas Kaskus regional Solo. Alat analisis data yang digunakan dalam penelitian ini adalah uji regresi linier berganda. Hasil penelitian ini menunjukan bahwa (1) kepercayaan konsumen berpengaruh positif terhadap keputusan pembelian secara elektronik. (2) risiko ecommerce tidak berpengaruh terhadap keputusan pembelian secara elektronik

PENGARUH ANKLE STRATEGY EXERCISE TERHADAP KESEIMBANGAN LANSIA DALAM MENGURANGI RISIKO JATUH: NARRATIVE REVIEW

Latar Belakang : Gangguan keseimbangan merupakan masalah kesehatan yang sering ditemui pada lansia. Lansia yang mengalami gangguan keseimbangan tubuh dan berisiko untuk jatuh memiliki kualitas hidup yang rendah. Ada berbagai macam modalitas fisioterapi salah satunya adalah Ankle Strategy Exercise, Ankle strategy exercise bermanfaat untuk meningkatkan keseimbangan, dan ankel strategi dapat meningkatkan kekuatan otot, lingkup gerak sendi, respon otot - otot sensoris yang sinergis, dan meningkatkan sisitem informasi sensoris. Tujuan : mengetahui pengaruh Ankle Strategy Exercise terhadap keseimbangan lansia. Metode Penelitian : metode penelitian ini adalah penelitian narrative review. Pencarian jurnal dilakukan di portal jurnal online seperti google scholar, PubMed, dan PEDro. Kriteria inklusi dalam penelitian ini yaitu jurnal penelitian full text berupa Ankle Strategy Exercise yang di gunakan untuk meningkatkan keseimbangan lansia, jurnal dalam bahasa Inggris maupun bahasa Indonesia, memiliki responden baik laki-laki maupun perempuan, diterbitkan tahun 2011-2021. Hasil penelusuran jurnal didapatkan sebanyak 10 jurnal. Hasil Penelitian : hasil review dari 10 jurnal di dapatkan bahwa Ankle Strategy Exercise dapat meningkatkan keseimbangan lansia dalam mengurangi risiko jatuh. Kesimpulan : ada pengaruh Ankle Strategy Exercise dalam meningkatkan keseimbangan lansia dalam mengurangi risiko jatuh

Over a millon Creatine Kinase due to a heavy work-out: A case report

Rhabdomyolysis induced by exercise is a very well known entity, several cases has been reported in the literature related with strenuous activities, weight lifting, marathon running, overexertion in an untrained person, knee bends, etc. We reported an interesting case of exercise-induced rhabdomyolysis in a 25 year old Hispanic male, after resuming his regular physical activity, with the highest creatine kinase described in the literature, successfully treated with aggressive hydration only and no complications

The role of pharmacists in developing countries: the current scenario in Pakistan

During the past few years, the pharmacy profession has expanded significantly in terms of professional services delivery and now has been recognized as an important profession in the multidisciplinary provision of health care. In contrast to the situation in developed countries, pharmacists in developing countries are still underutilized and their role as health care professionals is not deemed important by either the community or other health care providers. The aim of this paper is to highlight the role of pharmacists in developing countries, particularly in Pakistan. The paper draws on the literature related to the socioeconomic and health status of Pakistan's population, along with background on the pharmacy profession in the country in the context of the current directions of health care

Persistent Gastric Colonization with Burkholderia pseudomallei and Dissemination from the Gastrointestinal Tract following Mucosal Inoculation of Mice

Melioidosis is a disease of humans caused by opportunistic infection with the soil and water bacterium Burkholderia pseudomallei. Melioidosis can manifest as an acute, overwhelming infection or as a chronic, recurrent infection. At present, it is not clear where B. pseudomallei resides in the mammalian host during the chronic, recurrent phase of infection. To address this question, we developed a mouse low-dose mucosal challenge model of chronic B. pseudomallei infection and investigated sites of bacterial persistence over 60 days. Sensitive culture techniques and selective media were used to quantitate bacterial burden in major organs, including the gastrointestinal (GI) tract. We found that the GI tract was the primary site of bacterial persistence during the chronic infection phase, and was the only site from which the organism could be consistently cultured during a 60-day infection period. The organism could be repeatedly recovered from all levels of the GI tract, and chronic infection was accompanied by sustained low-level fecal shedding. The stomach was identified as the primary site of GI colonization as determined by fluorescent in situ hybridization. Organisms in the stomach were associated with the gastric mucosal surface, and the propensity to colonize the gastric mucosa was observed with 4 different B. pseudomallei isolates. In contrast, B. pseudomallei organisms were present at low numbers within luminal contents in the small and large intestine and cecum relative to the stomach. Notably, inflammatory lesions were not detected in any GI tissue examined in chronically-infected mice. Only low-dose oral or intranasal inoculation led to GI colonization and development of chronic infection of the spleen and liver. Thus, we concluded that in a mouse model of melioidosis B. pseudomallei preferentially colonizes the stomach following oral inoculation, and that the chronically colonized GI tract likely serves as a reservoir for dissemination of infection to extra-intestinal sites

Pengaruh Penerapan Sistem Aplikasi Penjualan Online Terhadap Volume Pendapatan Di Masa Pandemi Covid-19

Salah satu akibat dari pandemi COVID-19 adalah kesulitan para pemilik usaha dalam memasarkan produknya, selain itu, merek yang telah dibangun sudah menjadi tidak dikenal lagi karena otoritas publik telah menetapkan pembatasan sosial ruang lingkup yang sangat besar (PSBB) dan pemisahan sosial untuk menghambat laju dari kasus positif. Pemanfaatan Grabfood membantu dan mempermudah klien untuk melakukan pembelian makanan dan minuman dengan keuntungan klien tidak perlu pergi ke tempat makan untuk membeli makanan atau minuman dan tidak menyita banyak waktu klien untuk mendapatkan pesanan yang diinginkan. Tujuan dari penelitian ini adalah untuk mengetahui volume pendapatan online di Bakso Goreng Baper. Penelitian ini menggunakan metode penelitian deskriptif kuantitatif dengan data yang berasal dari pemilik perusahaan serta dokumen perusahaan yang dikumpulkan melalui observasi dan wawancara. Penelitian ini menemukan bahwa penjualan online di masa sebelum pandemi covid-19 tidak cukup berpengaruh dalam pendapatan bakso goreng baper. Di masa sebelum pandemi penjualan offline sangat mendominasi untuk pendapatan di bakso goreng baper. Sedangkan penjualan online di bakso goreng baper pada masa pandemi mengalami peningkatan yang cukup signifikan, namun penjualan offline tidak terlalu mengalami penurunan Keywords: Pandemi Covid-19, aplikasi penjualan online, penjualan offline, volume pendapata

Penerapan Algoritma Decision Tree C4.5 Dan C5.0 Untuk Klasifikasi Risiko Diabetes Melitus Tipe 2 Pada Pasien Klinik Griya Bromo Malang

C4.5 dan C5.0 merupakan algoritma decision tree untuk mengklasifikasikan objek ke dalam bentuk pohon. Pada algoritma C4.5 menggunakan nilai gain untuk menentukan urutan node, sedangkan pada algoritma C5.0 menggunakan nilai gain ratio. Tujuan menggunakan dua algoritma ini adalah memperoleh model klasifikasi dalam pohon keputusan, mengetahui faktor-faktor yang berpengaruh, dan mengetahui ketepatan klasifikasi risiko Diabetes Melitus tipe 2 pada pasien Klinik Griya Bromo Malang. Penelitian ini menggunakan data sekunder, dengan 150 objek data pasien dan 11 variabel gaya hidup pasien Klinik Griya Malang tahun 2021

Lipoprotein lipase deficiency in chronic kidney disease is accompanied by down-regulation of endothelial GPIHBP1 expression

BACKGROUND: Chronic renal failure (CRF) is associated with hypertriglyceridemia and impaired clearance of very low density lipoprotein (VLDL) and chylomicrons which are largely due to lipoprotein lipase (LPL) deficiency/dysfunction. After its release from myocytes and adipocytes, LPL binds to the endothelium in the adjacent capillaries where it catalyzes hydrolysis of triglycerides in VLDL and chylomicrons. The novel endothelium-derived molecule, glycosylphosphatidylinositol-anchored binding protein 1 (GPIHBP1), plays a critical role in LPL metabolism and function by anchoring LPL to the endothelium and binding chylomicrons. GPIHBP1-deficient mice and humans exhibit severe hypertriglyceridemia and diminished heparin-releasable LPL, pointing to the critical role of GPIHBP1 in regulation of LPL activity. Given its central role in regulation of LPL activity and triglyceride metabolism, we explored the effect of chronic kidney disease (CKD) on GPIHBP1 expression. METHODS: Expression of GPIHBP1 and LPL were determined by reverse transcriptase-polymerase chain reaction, Western blot and immunohistochemical analyses in the adipose tissue, skeletal muscle and myocardium of rats 12 weeks after 5/6 nephrectomy (CRF) or sham-operation (control). RESULTS: Compared to the controls, the CRF group exhibited severe hypertriglyceridemia, significant reduction of the skeletal muscle, myocardium and adipose tissue LPL mRNA and protein abundance. This was accompanied by parallel reductions of GPIHBP1 mRNA abundance and immunostaining in the tested tissues. CONCLUSIONS: LPL deficiency in CKD is associated with and compounded by GPIHBP1 deficiency. Together these abnormalities contribute to impaired clearance of triglyceride-rich lipoproteins, diminished availability of lipid fuel for energy storage in adipocytes and energy production in myocytes and consequent hypertriglyceridemia, cachexia, muscle weakness and atherosclerosis