Making land available for woodland creation

In order to support the Forestry Commission in achieving woodland planting targets, the overall aim of this research was to better understand the availability of land in England for afforestation, reflecting the interests and motivation of land owners and occupiers. In particular the research has attempted to identify where (either in a geographical sense and/or in terms of owner 'type') the Forestry Commission might focus its efforts in terms of accessing land for woodland creation

Maturation of the gastric microvasculature in Xenopus laevis (Lissamphibia, Anura) occurs at the transition from the herbivorous to the carnivorous lifestyle, predominantly by intussuceptive microvascular growth (IMG): a scanning electron microscope study of microvascular corrosion casts and correlative light microscopy

The microvascular bed of the stomach of Xenopus laevis and the changes it undergoes when the herbivorous tadpole becomes a carnivorous adult were studied by scanning electron microscopy of vascular corrosion casts and light microscopy of stained tissue sections. In tadpoles an upper and a lower gastric artery supplied, and upper, middle and lower medial and lateral gastric veins drained the vertically extending stomach. During metamorphosis, the stomach gained a horizontal cranio-caudal extension and vessels accordingly become dorsal and ventral gastric arteries, and anterior, middle and posterior gastric veins, respectively. Up to stage 64 (late climax) mucosal capillaries formed a polygonal network of wide immature-looking capillaries ensheathing gastric glands in a basket-like manner. From stage 64 onwards, blood vessels of the stomach appeared mature, revealed a clear hierarchy and were correlated closely with the histomorphology of the stomach, which had also gained the adult pattern. Within the gastric mucosa, ascending arterioles branched in a fountain-like pattern into wide subepithelial capillaries establishing a centripetal blood flow along the gastric glands, which makes an ultrashort control loop of glandular cells within the branched tubular gastric glands very unlikely. Formation of the stomach external muscular layer started at stage 57 when smooth muscle cells locally formed a single longitudinal and one-to-two single circular layers. Abundant signs of intussusceptive microvascular growth and rare vascular sprouts in vascular corrosion casts indicated that the larval-to-adult microvascular pattern formation of the stomach of Xenopus laevis Daudin occurs predominantly by non-sprouting angiogenesis

Ozone loss derived from balloon-borne tracer measurements in the 1999/2000 Arctic winter

Balloon-borne measurements of CFC11 (from the DIRAC in situ gas chromatograph and the DESCARTES grab sampler), ClO and O3 were made during the 1999/2000 Arctic winter as part of the SOLVE-THESEO 2000 campaign, based in Kiruna (Sweden). Here we present the CFC11 data from nine flights and compare them first with data from other instruments which flew during the campaign and then with the vertical distributions calculated by the SLIMCAT 3D CTM. We calculate ozone loss inside the Arctic vortex between late January and early March using the relation between CFC11 and O3 measured on the flights. The peak ozone loss (~1200ppbv) occurs in the 440-470K region in early March in reasonable agreement with other published empirical estimates. There is also a good agreement between ozone losses derived from three balloon tracer data sets used here. The magnitude and vertical distribution of the loss derived from the measurements is in good agreement with the loss calculated from SLIMCAT over Kiruna for the same days

Structural insights into regulation of nuclear receptors by ligands

Nuclear receptors are DNA-binding transcription factors, the transcriptional function of many of which depends on the binding of ligands, a feature that distinguishes nuclear receptors from other transcription factors. This review will summarize recent advances in our knowledge of the interaction between selected nuclear receptors and their cognate ligands

Clusters in the inner spiral arms of M51: the cluster IMF and the formation history

We study the cluster population in a region of 3.2x3.2 kpc^2 in the inner spiral arms of the intergacting galaxy M51, at a distance of about 1 to 3 kpc from the nucleus, based on HST--WFPC2 images taken through five broadband and two narrowband filters. We found 877 cluster candidates and we derived their ages, initial masses and extinctions by comparing their energy distribution with the Starburst99 cluster models. We describe the 3 and 2-dimensional least-square energy fitting method that was used (3DEF, 2DEF). The lack of [OIII] emission in even the youngest clusters with strong H-alpha emission, indicates the absence of the most massive stars and suggests a mass upper limit of about 25 to 30 solar masses. The mass versus age distribution of the clusters shows a drastic decrease in the number of clusters with age, which indicates that cluster disruption is occurring on a timescale of about 10 Myr for low mass clusters. The cluster initial mass function for clusters younger than 10 Myr has an exponent of alpha = 2.0 (+- 0.05) We derived the cluster formation history from clusters with an initial mass larger than 10^4 solar masses. There is no evidence for a peak in the cluster formation rate within a factor two at about 200 to 400 Myr ago, i.e. at the time of the interaction with the companion galaxy NGC 5194.Comment: 15 pages, 15 figures. Accepted for publication by Astronomy and Astrophysic

S2COSMOS: evolution of gas mass with redshift using dust emission

We investigate the evolution of the gas mass fraction for galaxies in the COSMOS field using submillimetre emission from dust at 850μm. We use stacking methodologies on the 850 μm S2COSMOS map to derive the gas mass fraction of galaxies out to high redshifts, 0 ≤ z ≤ 5, for galaxies with stellar masses of 109.

Clinicians' caseload management behaviours as explanatory factors in patients' length of time on caseloads : a predictive multilevel study in paediatric community occupational therapy

Peer reviewedPublisher PD

Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response

Mechanoadaptation maintains bone mass and architecture; its failure underlies age-related decline in bone strength. It is unclear whether this is due to failure of osteocytes to sense strain, osteoblasts to form bone or insufficient mechanical stimulus. Mechanoadaptation can be restored to aged bone by surgical neurectomy, suggesting that changes in loading history can rescue mechanoadaptation. We use non-biased, whole-bone tibial analyses, along with characterisation of surface strains and ensuing mechanoadaptive responses in mice at a range of ages, to explore whether sufficient load magnitude can activate mechanoadaptation in aged bone. We find that younger mice adapt when imposed strains are lower than in mature and aged bone. Intriguingly, imposition of short-term, high magnitude loading effectively primes cortical but not trabecular bone of aged mice to respond. This response was regionally-matched to highest strains measured by digital image correlation and to osteocytic mechanoactivation. These data indicate that aged bone’s loading response can be partially recovered, non-invasively by transient, focal high strain regions. Our results indicate that old murine bone does respond to load when the loading is of sufficient magnitude, and bones’ age-related adaptation failure may be due to insufficient mechanical stimulus to trigger mechanoadaptation