Comparación de distintas estrategias para la predicción de muerte a corto plazo en el paciente anciano infectado

Objective. The aim of this study was to determine the utility of a post hoc lactate added to SIRS and qSOFA score to predict 30-day mortality in older non-severely dependent patients attended for infection in the Emergency Department (ED). Methods. We performed an analytical, observational, prospective cohort study including patients of 75 years of age or older, without severe functional dependence, attended for an infectious disease in 69 Spanish ED for 2-day three seasonal periods. Demographic, clinical and analytical data were collected. The primary outcome was 30-day mortality after the index event. Results. We included 739 patients with a mean age of 84.9 (SD 6.0) years; 375 (50.7%) were women. Ninety-one (12.3%) died within 30 days. The AUC was 0.637 (IC 95% 0.587-0.688; p= 2 and 0.698 (IC 95% 0.635- 0.761; p= 2. Comparing receiver operating characteristic (ROC) there was a better accuracy of qSOFA vs SIRS (p=0.041). Both scales improve the prognosis accuracy with lactate inclusion. The AUC was 0.705 (IC95% 0.652-0.758; p<0.001) for SIRS plus lactate and 0.755 (IC95% 0.696-0.814; p<0.001) for qSOFA plus lactate, showing a trend to statistical significance for the second strategy (p=0.0727). Charlson index not added prognosis accuracy to SIRS (p=0.2269) or qSOFA (p=0.2573). Conclusions. Lactate added to SIRS and qSOFA score improve the accuracy of SIRS and qSOFA to predict short-term mortality in older non-severely dependent patients attended for infection. There is not effect in adding Charlson index

Precision Measurement of the Proton Flux in Primary Cosmic Rays from Rigidity 1 GV to 1.8 TV with the Alpha Magnetic Spectrometer on the International Space Station

A precise measurement of the proton flux in primary cosmic rays with rigidity (momentum/charge) from 1 GV to 1.8 TV is presented based on 300 million events. Knowledge of the rigidity dependence of the proton flux is important in understanding the origin, acceleration, and propagation of cosmic rays. We present the detailed variation with rigidity of the flux spectral index for the first time. The spectral index progressively hardens at high rigidities.</p

Elliptic flow of identified hadrons in Pb-Pb collisions at 1asNN = 2.76 TeV

The elliptic flow coefficient (v2) of identified particles in Pb-Pb collisions at 1asNN = 2.76 TeV was measured with the ALICE detector at the Large Hadron Collider (LHC). The results were obtained with the Scalar Product method, a two-particle corre- lation technique, using a pseudo-rapidity gap of | 06\u3b7| > 0.9 between the identified hadron under study and the reference particles. The v2 is reported for \u3c0\ub1, K\ub1, K0S, p+p, \u3c6, \u39b+\u39b, \u39e 12+\u39e+ and \u3a9 12+\u3a9+ in several collision centralities. In the low transverse momentum (pT) region, pT 3 GeV/c

Estudo da curva de crescimento de animais da raça Guzerá e seus cruzamentos alimentados a pasto, com e sem suplementação: 1. Análise e seleção das funções não-lineares Growth curve analysis of Guzera and their crossbreds fed under grazing with or without supplementation: 1. Analysis and selection of nonlinear functions

RESUMO - O objetivo deste trabalho foi analisar sete funções não-lineares para descrever o crescimento de machos e fêmeas da raça Guzerá e seus cruzamentos (3/4Guzerá-1/4Pardo Suíço, 1/2Nelore-1/4Pardo Suíço-1/4Guzerá, 1/2Pardo Suíço-1/2Guzerá, 1/2Chianina-1/4Pardo Suíço-1/4Guzerá, 1/2Caracú-1/2Guzerá, 1/2Caracu-1/4Pardo Suíço-1/4Guzerá) submetidos a três níveis de suplementação (sem, durante o período seco e o ano todo), a fim de analisar e selecionar uma função que apresentasse menores desvios de regressão, menor variação residual, maior coeficiente de determinação, menor variação entre os parâmetros dos animais, maior convergência e valor assintótico compatível com o peso adulto observado. A função que melhor se enquadrou nesses parâmetros de seleção foi a função de Gompertz, seguida da função de Von Bertalanffy. A função de Richards apresentou grande dificuldade computacional para o ajuste, resultando em baixa convergência. As funções de Brody apresentaram as maiores estimativas de peso adulto e a função de Gompertz modificada e Logística, as menores.<br>ABSTRACT - The objective of this work was to evaluate seven non linear functions to describe Guzera male and female growth curves, and their crossbreds (3/4Guzera-1/4Brown Swiss, 1/2Nellore-1/4Brown Swiss-1/4Guzera, 1/2Guzera-1/2Brown Swiss, 1/2Chianina- 1/4Brown Swiss-1/4Guzera, 1/2Caracu-1/2Guzera, 1/2Caracu-1/4Brown Swiss-1/4Guzera) submitted to three levels of supplementation (without, during the dry period and the whole year), to analize and to select one function which presented lower regression deviation, lower residual sum of squares, higher coefficient of determination, lower variation among animal parameters, higher convergence and assintotic compatible value with the observed mature weight. The function that best express these parameters of selection was the Gompertz, followed by the Von Bertalanffy function. The Richards function showed the high computational difficulty to the adjustment, resulting on lower convergence. Brody functions presented the largest and the modified Gompertz and Logistic functions showed the smallest mature weight

Performance Of The Alice Experiment At The Cern Lhc

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