Effective linkages and participatory governance in the management of veld fires

Integrated public governance is one of the challenges of Government. The importance of governmental departments, NGOs and stakeholders working together in a coordinated and well-managed manner in times of natural and man-initiated disasters, cannot be emphasised enough. To determine the nature and extent of this, the management of the most severe veld fires during 2008 in the Waterberg District of the Limpopo Province was researched with reference to the nature and extent of the integrated public governance achieved. The agricultural extension officers’ ability toestablish interest groups in the respective communities and to build linkages between themselves and other organisations and government institutions has proved invaluable in the quest of the Limpopo Province Department of Agriculture (LDA) to bring about more effective public service delivery in the Province. In the article, notice has been taken of the most prominent legislation in the field of agricultural public service rendering, and the way in which public management perse and governmental relations as ‘vehicles’ determined the level of effectiveness,efficiency and economy of the management of three major veld fires in the Alma, Rust de Winter and Dwaalboom areas. The response time by departmental officials of the various spheres of government and the ultimate time when governmental assistance was received, were compared.The vital roles of the Agricultural Extension Officer and the supporting offices of LDA in the management of agricultural related crises, are also highlighted. Lastly some logical conclusions are drawn and  recommendations made to improve the agricultural service rendering in the Province

Use of micro-computed tomography imaging and porosity measurements as indicators of collagen preservation in archaeological bone

Collagen isolated from archaeological bone is a common material for radiocarbon dating, stable isotope analysis, and zooarchaeology by mass spectrometry (ZooMS). However, not all bones contain extant collagen, leading to unnecessary destruction of unproductive bones and wasted laboratory time and resources. An aim of this research is to study bone diagenesis, particularly collagen destruction, in an effort to develop a minimally destructive method for identifying bones with high collagen content. In a multi-method study of variably preserved bones from Etton, Cambridgeshire, UK, we examined material properties of Neolithic cattle and sheep bones including porosity, surface area, and elemental composition. Micro-computed tomography (microCT) is an imaging technique that furnishes three-dimensional images of mineralized materials such as bone. Cortical bone porosity, the percentage of total bone volume consisting of empty space as calculated using microCT, can act as a proxy for bone collagen preservation. In general, bones with high cortical porosity are unlikely to contain sufficient collagen for further analysis. Bones with apparently low cortical porosity have a more varied range of collagen preservation. Bone samples with low porosity and no extant collagen often contain micropores with a diameter of 10 nm or less that cannot be seen in microCT images but are apparent in pore size distributions measured by mercury porosimetry, and indicated by high surface areas measured by nitrogen adsorption. Furthermore, a re-evaluation of light-induced breakdown spectroscopy data from this same assemblage confirms that ratios of calcium to fluorine may likewise indicate the state of diagenesis

Non-thermal processes in colliding-wind massive binaries: the contribution of Simbol-X to a multiwavelength investigation

Several colliding-wind massive binaries are known to be non-thermal emitters in the radio domain. This constitutes strong evidence for the fact that an efficient particle acceleration process is at work in these objects. The acceleration mechanism is most probably the Diffusive Shock Acceleration (DSA) process in the presence of strong hydrodynamic shocks due to the colliding-winds. In order to investigate the physics of this particle acceleration, we initiated a multiwavelength campaign covering a large part of the electromagnetic spectrum. In this context, the detailed study of the hard X-ray emission from these sources in the SIMBOL-X bandpass constitutes a crucial element in order to probe this still poorly known topic of astrophysics. It should be noted that colliding-wind massive binaries should be considered as very valuable targets for the investigation of particle acceleration in a similar way as supernova remnants, but in a different region of the parameter space.Comment: 4 pages, 2 figures, to appear in Proc. of the Second Internqtionql Simbol-X Symposium, held in Paris (France

Ciência Cidadã Extrema: Uma Nova Abordagem

A conservação da biodiversidade é uma questão que tem preocupado o mundo todo. Nas últimas décadas, centenas de áreas protegidas foram criadas para assegurar a preservação da biodiversidade no planeta. Um grande número de áreas protegidas é habitado por comunidades que dependem do uso de seus recursos naturais não apenas para a sua sobrevivência, mas também para a sua reprodução social e cultural. Em muitos casos, as populações locais têm sido diretamente responsáveis pela gestão sustentável desses complexos ecossistemas por séculos. Iniciativas de Ciência Cidadã – entendida como a participação de amadores, voluntários e entusiastas em projetos científicos – têm envolvido o público na produção científica e em projetos de monitoramento da biodiversidade, mas têm limitado essa participação à coleta de dados, e têm normalmente ocorrido em locais afluentes, excluindo as populações não alfabetizadas ou letradas e que vivem em áreas remotas. Povos e comunidades tradicionais conhecem os aspectos ambientais das áreas por eles habitadas, o que pode ser benéfico para a gestão e o monitoramento bem-sucedidos da biodiversidade. Portanto, ao se tratar do monitoramento e da proteção da biodiversidade em áreas habitadas por populações humanas, o seu envolvimento é central e pode conduzir a um cenário onde todas as partes envolvidas se beneficiam. Extreme Citizen Science (ExCiteS) é um grupo de pesquisa interdisciplinar criado em 2011, na University College London, com a finalidade de avançar o atual conjunto de práticas da Ciência Cidadã. A ideia é permitir que qualquer comunidade, em qualquer lugar do mundo – desde grupos marginalizados que vivem nas periferias de áreas urbanas até grupos de caçadores e coletores da floresta amazônica –, comece um projeto de Ciência Cidadã para lidar com suas próprias questões. Este artigo apresenta os diversos aspectos que tornam a Ciência Cidadã “extrema” no trabalho do grupo ExCiteS, por meio da exposição de suas teorias, métodos e ferramentas, e dos estudos de caso atuais que envolvem comunidades tradicionais ao redor do mundo. Por fim, ressalta-se a maior preocupação do grupo, que é tornar a participação verdadeiramente efetiva, e sugere-se como iniciativas de monitoramento da biodiversidade podem ser realizadas de maneira colaborativa, trazendo benefícios a todos os atores envolvidos

The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer

The controlled assembly of replication forks is critical for genome stability. The Dbf4-dependent Cdc7 kinase (DDK) initiates replisome assembly by phosphorylating the MCM2-7 replicative helicase at the N-terminal tails of Mcm2, Mcm4 and Mcm6. At present, it remains poorly understood how DDK docks onto the helicase and how the kinase targets distal Mcm subunits for phosphorylation. Using cryo-electron microscopy and biochemical analysis we discovered that an interaction between the HBRCT domain of Dbf4 with Mcm2 serves as an anchoring point, which supports binding of DDK across the MCM2-7 double-hexamer interface and phosphorylation of Mcm4 on the opposite hexamer. Moreover, a rotation of DDK along its anchoring point allows phosphorylation of Mcm2 and Mcm6. In summary, our work provides fundamental insights into DDK structure, control and selective activation of the MCM2-7 helicase during DNA replication. Importantly, these insights can be exploited for development of novel DDK inhibitors

Bilateral ischemic optic neuropathy after transurethral prostatic resection: a case report

BACKGROUND: Nonarteritic ischemic optic neuropathy affects the anterior portion of the optic nerve and is characterized by sudden, painless visual loss. The affected eye has a relative afferent pupillary defect. The typical funduscopic appearance includes optic disc edema, with associated nerve fiber layer hemorrhage. Risk factors include advanced age, systemic hypertension, nocturnal hypotension, diabetes mellitus, and a small cup-to-disc ratio. Bilateral presentation is rare. Postoperative optic neuropathy has been associated with nonocular surgery; risk factors include a combination of prolonged surgical times, acute systemic hypotension, anemia due to blood loss, or prone positioning. We report for the first time a patient with bilateral, simultaneous anterior ischemic optic neuropathy after elective transurethral prostatic resection. CASE PRESENTATION: A 66-year old man underwent surgery for benign prostatic hyperplasia. The preoperative blood pressure was 140/85 mmHg, hemoglobin 15.9 g/dL, and hematocrit 48.6%. Two hours postoperatively, the blood pressure, hemoglobin, and hematocrit dropped dramatically. One day later, transient horizontal diplopia developed. Funduscopy showed a congenitally small cup-to-disc ratio without papillary edema. Other ocular findings were unremarkable. By 4 days postoperatively, sudden and painless amaurosis bilaterally developed when the patient awoke with nausea and vomiting. Visual acuity was no light perception bilaterally. The optic discs were swollen with small hemorrhages. Scans of the head and orbits and electrolyte levels were normal. There were no responses on visual evoked potentials bilaterally. The blood pressure was 90/50 mm Hg, the hemoglobin 7.0 g/dL, and the hematocrit 22.9%, necessitating infusion of three units of packed red blood cells. The blood pressure, hematocrit, and hemoglobin increased to normal levels. Three months later the visual acuity remained no light perception. The pupils were unreactive and there was marked optic disc atrophy bilaterally. CONCLUSION: Bilateral and simultaneous acute ischemic optic neuropathy may be a rare but devastating surgical complication. The combination of anemia and hypotension may increase the risk of anterior ischemic optic neuropathy postoperatively after transurethral prostatic resection

Pleosporales

One hundred and five generic types of Pleosporales are described and illustrated. A brief introduction and detailed history with short notes on morphology, molecular phylogeny as well as a general conclusion of each genus are provided. For those genera where the type or a representative specimen is unavailable, a brief note is given. Altogether 174 genera of Pleosporales are treated. Phaeotrichaceae as well as Kriegeriella, Zeuctomorpha and Muroia are excluded from Pleosporales. Based on the multigene phylogenetic analysis, the suborder Massarineae is emended to accommodate five families, viz. Lentitheciaceae, Massarinaceae, Montagnulaceae, Morosphaeriaceae and Trematosphaeriaceae

Nol9 is a novel polynucleotide 5′-kinase involved in ribosomal RNA processing

The production and processing of ribosomal RNA is an essential and complex process. Here, a polynucleotide 5′-kinase, Nol9, is shown to have an important function in pre-rRNA processing and 60S ribosomal subunit biogenesis