Universal newborn screening: A roadmap for action.

Newborn screening (NBS) prevents morbidity and mortality by screening babies for selected disorders in the first days of life so that early diagnosis and treatment can be initiated. Congenital disorders impact an estimated 8 million or 6% of annual births worldwide, and of the top five that contribute 25% to the global burden of these disorders, three can be identified and managed by NBS. There are determined pockets of activity in Latin America, Sub-Saharan Africa, and the Asia Pacific region, where partnerships among government, non-governmental organizations, academia, the private sector and civil society are developing novel NBS programs that are both saving lives and preventing disability in those who survive

Universal newborn screening: A roadmap for action.

Newborn screening (NBS) prevents morbidity and mortality by screening babies for selected disorders in the first days of life so that early diagnosis and treatment can be initiated. Congenital disorders impact an estimated 8 million or 6% of annual births worldwide, and of the top five that contribute 25% to the global burden of these disorders, three can be identified and managed by NBS. There are determined pockets of activity in Latin America, Sub-Saharan Africa, and the Asia Pacific region, where partnerships among government, non-governmental organizations, academia, the private sector and civil society are developing novel NBS programs that are both saving lives and preventing disability in those who survive

Crossdating Juniperus procera from North Gondar, Ethiopia

The application of dendrochronology in (sub)tropical regions has been limited by the difficulty in finding trees with distinct annual rings that can be crossdated. Here, we report successful crossdating of Juniperus procera trees from North Gondar, Ethiopia. The trees form annual rings in response to a unimodal rainfall regime. The selection of mesic locations ensured that the trees did not respond to intra-seasonal weather anomalies. Crossdating was achieved by comparison of the wood anatomy directly on the surface of the core samples and purpose-adapted skeleton plotting. Wood-anatomical anomalies, such as false and indistinct rings, were regarded as potentially replicated features and used in crossdating. COFECHA yielded site-specific mean series inter-correlations between 0.52 and 0.59. AMS radiocarbon dating during the bomb era indicated that dating uncertainty is ±1 year

Narratives of nineteenth century drought in southern Africa in different historical source types

Single- to multiple-year drought episodes posed significant challenges for agrarian communities across southern Africa during the nineteenth century and hence are widely recorded in a variety of historical documents. However, the ways in which droughts are articulated, and the focus of individual accounts, vary considerably between different authors and historical source types. This study draws on a range of documentary source types—specifically newspapers, letters, reports and diaries—to explore the varied narratives associated with three protracted droughts (those of 1861–1863, 1876–1879 and 1895–1897) that affected large areas of the subcontinent. The analysis spans four case study areas—present day KwaZulu-Natal (South Africa), Lesotho, Malawi and the southern Kalahari (Botswana and South Africa)—which were investigated as part of different interdisciplinary projects. We explore issues common to all case study areas, including (i) how specific drought events are framed and (ii) what is and is not reported about individual droughts across different source types. We conclude that different source types in the subcontinent may be more or less appropriate for addressing the specific objectives of historical climatology, particularly in relation to historical drought. Sources such as newspapers and weather diaries are rich in qualitative and quantitative observations suitable for the reconstruction of temporal and spatial patterns of weather and climate, as well as climate-related natural disasters. In contrast, letters, reports and personal journals, especially those written by missionaries, provide additional qualitative narratives through which to investigate the vulnerability of past societies and economies to climate variations, and to explore past discourses and social representations of climate. While studies of this kind have been published for European and American source types, this is the first systematic exploration of documentary sources for the historical climatology of Africa. It should therefore provide a guide for climate history studies elsewhere in the continent, or other regions where written records are absent prior to the arrival of European colonists