23 research outputs found
Antidiabetogenic action of glucagon-like peptide- 1 related to administration relative to meal intake in subjects with type 2 diabetes
Glucagon-like peptide-1 retards gastric emptying and small bowel transit in the rat: Effect mediated through central or enteric nervous mechanisms
Ubiquitous karst hydrological control on speleothem oxygen isotope variability in a global study
Speleothem oxygen isotopic (δ¹⁸O) records are used to reconstruct past hydroclimate yet records from the same cave do not always replicate. We use a global database of speleothem δ18O to quantify the replicability of records to show that disagreement is common worldwide, occurs across timescales and is unrelated to climate, depth or lithology. Our global analysis demonstrates that within-cave differences in mean speleothem δ¹⁸O values are consistent with those of dripwater, supporting a ubiquitous influence of flowpaths. We present a case study of four new stalagmite records from Golgotha Cave, southwest Australia, where the isotopic differences between them are informed by cave monitoring. It is demonstrated that karst hydrology is a major driver of within-cave speleothem and dripwater δ¹⁸O variability, primarily due to the influence of fractures on flowpaths. Applying our understanding of water movement through fractures assists in quantitative reconstruction of past climate variability from speleothem δ¹⁸O records.Pauline C. Treble, Andy Baker, Nerilie J. Abram, John C. Hellstrom, Jagoda Crawford, Michael K. Gagan, Andrea Borsato, Alan D. Griffiths, Petra Bajo, Monika Markowska, Stacey C. Priestley, Stuart Hankin, David Paterso
The last 11 glacial-interglacial cycles recorded in a single speleothem from Corchia Cave
International audienc
Separation of Human B Lymphocytes on Helix pomatia A Haemagglutinin into Two Major Fractions Differing in Responsiveness to T-dependent Mitogen (Pokeweed Mitogen) or Antigen (Tetanus Toxoid)
Hydrological control of the dead carbon fraction in a Holocene tropical speleothem
Over the past decade, a number of speleothem studies have used radiocarbon (C-14) to address a range of palaeoclimate problems. These have included the use of the bomb pulse C-14 to anchor chronologies over the last 60 years, the combination of U-Th and C-14 measurements to improve the radiocarbon age-calibration curve, and linking atmospheric C-14 variations with climate change. An issue with a number of these studies is how to constrain, or interpret, variations in the amount of radioactively dead carbon (i.e. the dead carbon fraction, or DCF) that reduces radiocarbon concentrations in speleothems. In this study, we use C-14, stable-isotopes, and trace-elements in a U-Th dated speleothem from Flores, Indonesia, to examine DCF variations and their relationship with above-cave climate over the late Holocene and modern era. A strong association between the DCF and hydrologically-controlled proxy data suggests that more dead carbon was being delivered to the speleothem during periods of higher cave recharge (i.e. lower delta O-18, delta C-13 and Mg/Ca values), and hence stronger summer monsoon. To explore this relationship, we used a geochemical soil-karst model coupled with C-14 measurements through the bomb pulse to disentangle the dominant components governing DCF variability in the speleothem. We find that the DCF is primarily controlled by limestone dissolution associated with changes in open- versus closed-system conditions, rather than kinetic fractionation and/or variations in the age spectrum of soil organic matter above the cave. Therefore, we infer that periods of higher rainfall resulted in a higher DCF because the system was in a more closed state, which inhibited carbon isotope exchange between the karst water dissolved inorganic carbon and soil-gas CO2, and ultimately led to a greater contribution of dead carbon from the bedrock. Published by Elsevier B.V
Stalagmite evidence for the onset of the Last Interglacial in southern Europe at 129 a 1 ka
A stable isotope record from a stalagmite collected from Antro del Corchia cave (Apuan Alps,
Central Italy), supported by 17 uranium-series ages, indicates enhanced regional rainfall between
ca. 8.9 and 7.3 kyr cal. BP at the time of sapropel S1 deposition. Within this phase, the highest
rainfall occurred between 7.9 and 7.4 kyr cal. BP. Comparison with different marine and lake
records, and in particular with the Soreq Cave record (Israel), suggests substantial in-phase
occurrence of enhanced rainfall between the Western and Eastern Mediterranean basins. There is no
convincing evidence for major climatic change at the time of the “8.2 ka event”