2,056 research outputs found

    Film and the Archive: Nation, Heritage, Resistance

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    This article analyses a range of discourses articulated around the figure of the film archive between the late nineteenth and the early twenty-first centuries, accounting for the various possibilities that they open up for considering audiovisual heritage as a potential space either for revolutionary change or for political or textual resistance. Focused mainly on archival discourses in Mexico, the article traces their interaction with both national-historical and anti-imperialist narratives, and the implications of digital and online culture for the encounter between the archiving of film and resistance. It accounts for the position of the archive in negotiations between state and private capital and spaces of artistic autonomy, and for the relationships between the archive, modernity, postmodernity and the notion of posterity

    A Non-Parametric Bayesian Approach to Spike Sorting

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    Abstract — In this work we present and apply infinite Gaussian mixture modeling, a non-parametric Bayesian method, to the problem of spike sorting. As this approach is Bayesian, it allows us to integrate prior knowledge about the problem in a principled way. Because it is non-parametric we are able to avoid model selection, a difficult problem that most current spike sorting methods do not address. We compare this approach to using penalized log likelihood to select the best from multiple finite mixture models trained by expectation maximization. We show favorable offline sorting results on real data and discuss ways to extend our model to online applications

    Adaptive modulation of antibiotic resistance through intragenomic coevolution

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    Bacteria gain antibiotic resistance genes by horizontal acquisition of mobile genetic elements (MGEs) from other lineages. Newly acquired MGEs are often poorly adapted causing intragenomic conflicts; these are resolved by either compensatory adaptation—of the chromosome or the MGE—or reciprocal coadaptation. The footprints of such intragenomic coevolution are present in bacterial genomes, suggesting an important role promoting genomic integration of horizontally acquired genes, but direct experimental evidence of the process is limited. Here we show adaptive modulation of tetracycline resistance via intrage- nomic coevolution between Escherichia coli and the multidrug resistant plasmid RK2. Tetracycline treatments, including mono- therapy or combination therapies with ampicillin, favoured de novo chromosomal resistance mutations coupled with mutations on RK2 impairing the plasmid-encoded tetracycline efflux pump. These mutations together provided increased tetracycline resistance at reduced cost. Additionally, the chromosomal resistance mutations conferred cross-resistance to chloramphenicol. Reciprocal coadaptation was not observed under ampicillin-only or no antibiotic selection. Intragenomic coevolution can create genomes comprising multiple replicons that together provide high-level, low-cost resistance, but the resulting co-dependence may limit the spread of coadapted MGEs to other lineages

    An update of the UK’s test reference year: The implications of a revised climate on building design

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    Copyright © 2015 SAGE PublicationsAverage weather years have been used around the world for testing buildings to ascertain their likely energy use using thermal modelling software. In the UK, the Test Reference Years which are in current use were released in 2006 but generally consisted of data from 1983 to 2004. In this work, revised test reference years will be proposed which are based on a new climatic period from 1984 to 2013. The differences between the two years will be highlighted and the implications for building design will be discussed.Engineering and Physical Sciences Research Council (EPSRC)CIBS

    Del compendio fílmico al relato histórico. Documentos sobre la realización de Memorias de un mexicano (Carmen Toscano, 1950)

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    Documents on the production of Memoirs of a Mexican (Carmen Toscano, 1950).Keywords: Salvador Toscano, Carmen Toscano, Memoirs of a Mexican, compilation film, Mexican revolution.___________Del compendio fílmico al relato histórico. Resumen: Documentos sobre la realización de Memorias de un mexicano (Carmen Toscano, 1950)Palabras clave: Salvador Toscano, Carmen Toscano, Memorias de un mexicano, cine de compilación, Revolución mexicana.___________Do compendio fílmico ao relato histórico. Resumo: Documentos sobre a realização de Memorias de um mexicano (Carmen Toscano, 1950)Palavras chave: Salvador Toscano, Carmen Toscano, Memorias de um mexicano, compilação, Revolução mexicana.Documentos sobre la realización de Memorias de un mexicano (Carmen Toscano, 1950).Palabras clave: Salvador Toscano, Carmen Toscano, Memorias de un mexicano, cine de compilación, Revolución mexicana.___________From film compendium to historical narrative. Documents on the production of Memoirs of a Mexican (Carmen Toscano, 1950)Abstract: Documents on the production of Memoirs of a Mexican (Carmen Toscano, 1950).Keywords: Salvador Toscano, Carmen Toscano, Memoirs of a Mexican, compilation film, Mexican revolution.___________Do compendio fílmico ao relato histórico. Documentos sobre a realização de Memorias de um mexicano (Carmen Toscano, 1950)Resumo: Documentos sobre a realização de Memorias de um mexicano (Carmen Toscano, 1950).Palavras chave: Salvador Toscano, Carmen Toscano, Memorias de um mexicano, compilação, Revolução mexicana

    Analytical solution of the tooling/workpiece contact interface shape during a flow forming operation

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    Flow forming involves complicated tooling/workpiece interactions. Purely analytical models of the tool contact area are difficult to formulate, resulting in numerical approaches that are case-specific. Provided are the details of an analytical model that describes the steady-state tooling/workpiece contact area allowing for easy modification of the dominant geometric variables. The assumptions made in formulating this analytical model are validated with experimental results attained from physical modelling. The analysis procedure can be extended to other rotary forming operations such as metal spinning, shear forming, thread rolling and crankshaft fillet rolling.Comment: 28 pages, 11 figure

    PRESERVATIVE TREATMENT OF TASMANIAN PLANTATION EUCALYPTUS NITENS USING SUPERCRITICAL FLUIDS

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    Short rotation plantation forests in Tasmania, Australia, are dominated by Eucalyptus nitens (common name: shining gum). These forests were primarily planted to provide material for pulp and paper production, but the timber is increasingly sought after for higher value and more enduring applications. Plantation E. nitens has a high proportion of low durability heartwood that resists penetration by conventional fluid preservatives. This limits its use to indoor applications. One approach to overcoming the refractory nature of E. nitens is to modify the treatment fluid. We investigated the use of supercritical carbon dioxide to deliver biocides deep into the wood. Timbers varying in thickness from 19 to 35 mm and 900 mm long were treated with a multicomponent biocide under supercritical conditions in a commercial facility in Denmark. The resulting timber was cut into zones inward from the surface. Wood from these zones was ground and extracted for HPLC analysis for tebuconazole and propiconazole. Preservative was detected in the inner portion of every sample examined, indicating that the process resulted in treatment throughout the boards, with concentrations meeting and on average exceeding the targeted amounts

    Modelling the future of the Hawaiian honeycreeper : an ecological and epidemiological problem

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    The Hawaiian honeycreeper (Drepanididae) faces the threat of extinction; this is believed to be due primarily to predation from alien animals, endemic avian malaria (Plasmodium relictum) and climate change. A deterministic SI modelling approach is developed, incorporating these three factors and a metapopulation approach in conjunction with a quasi-equilibrium assumption to simplify the vector populations. This enables the qualitative study of the behaviour of the system. Numerical results suggest that although (partial) resistance to avian malaria may be advantageous for individual birds, allowing them to survive infection, this allows them to become carriers of infection and hence greatly increases the spread of this disease. Predation obviously reduces the life-expectancy of honeycreepers, but in turn this reduces the spread of infection from resistant carriers; therefore the population-level impact of predation is reduced. Various control strategies proposed in the literature are also considered and it is shown that predation control could either help or hinter, depending upon resistance of the honeycreeper species. Captive propagation or habitat restoration may be the best feasible solution to the loss of both heterogeneity within the population and the loss of the species as a whole

    Operating at the extreme: Estimating the upper yield boundary of winter wheat production in commercial practice

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    © 2020 The Authors. Wheat farming provides 28.5% of global cereal production. After steady growth in average crop yield from 1950 to 1990, wheat yields have generally stagnated, which prompts the question of whether further improvements are possible. Statistical studies of agronomic parameters such as crop yield have so far exclusively focused on estimating parameters describing the whole of the data, rather than the highest yields specifically. These indicators include the mean or median yield of a crop, or finding the combinations of agronomic traits that are correlated with increasing average yields. In this paper, we take an alternative approach and consider high yields only. We carry out an extreme value analysis of winter wheat yield data collected in England and Wales between 2006 and 2015. This analysis suggests that, under current climate and growing conditions, there is indeed a finite upper bound for winter wheat yield, whose value we estimate to be 17.60 tonnes per hectare. We then refine the analysis for strata defined by either location or level of use of agricultural inputs. We find that there is no statistical evidence for variation of maximal yield depending on location, and neither is there statistical evidence that maximum yield levels are improved by high levels of crop protection and fertilizer use
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