Resonantly damped oscillations of longitudinally stratified coronal loops

Soon after coronal loop oscillations were observed by TRACE spacecraft for the first time in 1999, various theoretical models have been put forward to explain the rapid damping of the oscillations of these intriguing objects. Coronal loop oscillations are often interpreted as fast kink modes of a straight cylindrical magnetic flux tube with immovable edges modelling dense photospheric plasma at the ends of the loop. Taking this model as a basis we use cold plasma approximation and consider the tube to be thin to simplify the problem and be able to deal with it analytically. In its equilibrium state the tube is permeated by a homogeneous magnetic field directed along the tube axis. We include the effect of stratification in our model supposing that plasma density varies along the tube. There is also density inhomogeneity in the radial direction confined in a layer with thickness much smaller than the radius of the tube. Considering the system of linearized MHD equations we study the dependence of the spectrum of tube oscillations and its damping due to resonant absorption on the parameters of the unperturbed state. The implication of the obtained results on coronal seismology is discussed

Electronic structure and optical properties of lightweight metal hydrides

We study the electronic structures and dielectric functions of the simple hydrides LiH, NaH, MgH2 and AlH3, and the complex hydrides Li3AlH6, Na3AlH6, LiAlH4, NaAlH4 and Mg(AlH4)2, using first principles density functional theory and GW calculations. All these compounds are large gap insulators with GW single particle band gaps varying from 3.5 eV in AlH3 to 6.5 eV in the MAlH4 compounds. The valence bands are dominated by the hydrogen atoms, whereas the conduction bands have mixed contributions from the hydrogens and the metal cations. The electronic structure of the aluminium compounds is determined mainly by aluminium hydride complexes and their mutual interactions. Despite considerable differences between the band structures and the band gaps of the various compounds, their optical responses are qualitatively similar. In most of the spectra the optical absorption rises sharply above 6 eV and has a strong peak around 8 eV. The quantitative differences in the optical spectra are interpreted in terms of the structure and the electronic structure of the compounds.Comment: 13 pages, 10 figure

Fast magnetoacoustic waves in curved coronal loops. I, Trapped and leaky modes

A study of vertically polarised fast magnetoacoustic waves in a curved coronal loop is presented. The loop is modeled as a semi-circular magnetic slab in the zero plasma-β limit. The governing equations for linear waves are derived. We show that the wave mode behaviour depends on the slope of the equilibrium density profile, which is modeled as a piece-wise continuous power law curve of index α. For all profiles, except for α = −4, wave modes are not trapped in the loop and leak out into the external medium through wave tunneling. The particular case of α = −4, which corresponds to a linearly increasing Alfvén speed profile, is examined in more detail as this is the only model that can support trapped wave modes. We compare the results with a straight slab model and find similar behaviour. Coupling between sausage and kink wave modes has not been found in the model

Seismology of curved coronal loops with vertically polarised transverse oscillations

Aims. Using a model of vertically polarised fast magnetoacoustic waves in curved coronal loops, the method of coronal seismology is applied to observations of transverse loop oscillations. Methods. A coronal loop is modeled as a curved magnetic slab in the zero plasma-β limit. For an arbitrary piece-wise continuous power law equilibrium density profile, the dispersion relation governing linear vertically polarised fast magnetoacoustic kink waves is derived. The ways in which this model can be used for coronal seismology are explored and applied to two observational examples. Results. The Alfvén speed and equilibrium density profile are determined from observations. It is shown that the mechanism of lateral leakage of fast magnetoacoustic kink oscillations described in this model is efficient. In fact, the damping is so efficient that in order to match predicted values with observational ones, either the loop needs to be highly contrasted or the transverse Alfvén speed profile needs to be close to linear. Possible improvements to make the modeling of lateral wave leakage in loops more realistic, allowing a lower damping efficiency, are discussed

On the Ratio of Periods of the Fundamental Harmonic and First Overtone of Magnetic Tube Kink Oscillations

We study kink oscillations of thin magnetic tubes. We assume that the density inside and outside the tube (and possibly also the cross-section radius) can vary along the tube. This variation is assumed to be of such a form that the kink speed is symmetric with respect to the tube centre and varies monotonically from the tube ends to the tube centre. Then we prove a theorem stating that the ratio of periods of the fundamental mode and first overtone is a monotonically increasing function of the ratio of the kink speed at the tube centre and the tube ends. In particular, it follows from this theorem that the period ratio is lower than two when the kink speed increases from the tube ends to its centre, while it is higher than two when the kink speed decreases from the tube ends to its centre. The first case is typical for non-expanding coronal magnetic loops, and the second for prominence threads. We apply the general results to particular problems. First we consider kink oscillations of coronal magnetic loops. We prove that, under reasonable assumptions, the ratio of the fundamental period to the first overtone is lower than two and decreases when the loop size increases. The second problem concerns kink oscillations of prominence threads. We consider three internal density profiles: generalised parabolic, Gaussian, and Lorentzian. Each of these profiles contain the parameter (Formula presented.) that is responsible for its sharpness. We calculate the dependence of the period ratio on the ratio of the mean to the maximum density. For all considered values of (Formula presented.) we find that a formula relating the period ratio and the ratio of the mean and maximum density suggested by Soler, Goossens, and Ballester (Astron. Astrophys.575, A123, 2015) gives a sufficiently good approximation to the exact dependence

Coronal loop seismology using multiple transverse loop oscillation harmonics

Context. TRACE observations (23/11/1998 06:35:57−06:48:43 UT) in the 171 Å bandpass of an active region are studied. Coronal loop oscillations are observed after a violent disruption of the equilibrium. Aims. The oscillation properties are studied to give seismological estimates of physical quantities, such as the density scale height. Methods. A loop segment is traced during the oscillation, and the resulting time series is analysed for periodicities. Results. In the loop segment displacement, two periods are found: 435.6 ± 4.5 s and 242.7 ± 6.4 s, consistent with the periods of the fundamental and 2nd harmonic fast kink oscillation. The small uncertainties allow us to estimate the density scale height in the loop to be 109 Mm, which is about double the estimated hydrostatical value of 50 Mm. Because a loop segment is traced, the amplitude dependence along the loop is found for each of these oscillations. The obtained spatial information is used as a seismological tool to give details about the geometry of the observed loop

Tuberculosis outcomes related to the Mycobacterium tuberculosis genotype

Mycobacterium tuberculosis strains of different phylogenetic lineages and genetic families differ in biological properties that determine, to some extent, epidemiological features and clinical manifestation in tuberculosis (TB) patients.The aim of the study was to assess the risk of an adverse outcome of the disease in TB patients caused by various M. tuberculosis genotypes.Materials and methods. A total of 425 patients with respiratory TB were enrolled in this study. They were registered at phthisiatric facilities in the Omsk region from March 2015 to June 2017 period and included: males — 73.1%, mean age 39.9 years, females — 26.9%, mean age 42.0 years. M. tuberculosis culture and drug susceptibility testing and DNA extraction were performed in accordance with standard methods. Strains were assigned to the M. tuberculosis Beijing genotype and its epidemiologically relevant clusters B0/W148 and 94-32 by PCR based detection of specific markers. Non-Beijing strains were subjected to spoligotyping.Results. We found that 66.5% isolates belonged to the Beijing genotype, 12.8% — to LAM, 10.1% — to T, and 4.7% — to the Ural genotype. Multi-drug resistance (MDR) to anti-TB drugs was observed in 195 M. tuberculosis strains (45.9%). Moreover, Beijing genotype was more often isolated from patients with MDR-TB infection (PR = 2.09 (95% CI 1.6–2.74) and TB infection associated with HIV infection (PR = 1.14 (95% CI 1.01–1.31). Lethal outcome was double higher in patients infected with Beijing vs. non-Beijing strains, 28.6% vs. 14.0% (PR = 2.03; 95% CI 1.3–3.17). The risk factors were identified as follows: young age 18–44 years (RR = 1.7; 95% CI 1.18–2.7), co-morbidity with HIV (RR = 5.0; 95% CI 3.39–7.45), multiple (RR = 1.7; 95% CI 1.14–2.55) and extensive drug resistance (RR = 2.57; 95% CI 1.35–4.92), and association with the Beijing genotype (RR = 2.0, 95% CI 1.3–3.17).Conclusion. M. tuberculosis spread in the Omsk region is characterised by significant prevalence of the Beijing genotype, associated with multiple and extensive drug resistance. A significant association of adverse clinical outcomes and various factors, including association with the Beijing genotype, requires development of new approaches in the fight against tuberculosis

The effect of flows on transverse oscillations of coronal loops

In this paper we study kink oscillations of coronal loops in the presence of flows. Using the thin-tube approximation we derive the general governing equation for kink oscillations of a loop with the density varying along the loop in the presence of flows. This equation remains valid even when the density and flow are time dependent. The derived equation is then used to study the effect of flows on eigenfrequencies of kink oscillations of coronal loops. The implication of the obtained results on coronal seismology is discussed

Cytotoxic effect of the VVGMCSF-Lact oncolytic virus against 3D cultures of human glioblastoma cells U-87 MG

Background. One of the promising methods of treating tumors is virotherapy, which is based on direct lysis of cancer cells by a virus and a virus-mediated antitumor immune response of the body. For the recombinant vaccinia virus strain VVGMCSF-Lact, producing human GMCSF and the oncotoxic protein lactaptin, cytotoxic and antitumor effects were shown in experiments in vitro and in vivo, respectively, when using adhesive cultures of U-87 MG human glioblastoma cells. 3D cultures are a more relevant tumor model than adhesive models, as they more fully reflect the realistic scenario of cancer development, as well as the response of the tumor to anticancer therapy.The aim. To evaluate the cytotoxic effect of the oncolytic virus VV-GMCSF-Lact against 3D cultures of human glioblastoma U-87 MG.Materials and methods. The following methods were used in the work: cultivation of 3D cell cultures, cytofluorometry, microscopic analysis, virus titration, statistical analysis.Results. U-87 MG cells were transduced with a lentiviral vector carrying the GFP reporter gene. The cytotoxicity of the VV-GMCSF-Lact virus (IC50) against the studied cells was 0.024 PFU/cell. U-87 MG cells were cultured under conditions for the formation of 3D structures. Microscopic analysis showed the oncolytic effect of the virus on the cells of 3D cultures as early as 24 hours after the start of incubation. Flow cytometry showed an increase in the granularity of glioblastoma cells under the action of the virus, which indicates active replication of the virus in the cells. The virus titer was 0.44 PFU/cell.Conclusions. The recombinant VV-GMCSF-Lact virus has a cytotoxic effect on 3D human glioblastoma U-87 MG cell cultures and actively replicates in them. In the future, to test the oncolytic effect of VV-GMCSF-Lact, it is planned to use not only 3D human glioblastoma cultures, but also cerebral organelles obtained in the process of cocultivation of glioblastoma cells and induced human pluripotent cells

Methodology of interdisciplinary projects in a foreign languagein the university

The study presents methodology of interdisciplinary projects in a foreign language as one of the effective teaching tools not only in the aspect of teaching a foreign language but also research work, intercultural interaction, information and communication technologies and professional communication.В данном исследовании представлен метод междисциплинарных проектов на иностранном языке, как один из эффективных методов обучения не только иностранному языку, но и научно-исследовательской работе, межкультурному взаимодействию, использованию информационно-коммуникационных технологий и профессиональной коммуникации