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17 research outputs found

Effect of the COVID-19 pandemic on surgery for indeterminate thyroid nodules (THYCOVID): a retrospective, international, multicentre, cross-sectional study

Author: Abdallah A.
Abentroth A. L.
Acheimastos V.
Agunaoun M.
Al Bisher H. M.
Al Ghuzlan A.
Al-Suhaimi E. A.
Alakus H.
Alkan M.
Almaraz Almaraz M. C.
Altmeier J.
Amram K.
Anajar S.
Anesidis S.
Anestiadou E.
Angelucci D.
Ansaldo G. L.
Antonopoulou M. I.
Arciniegas M.
Arikan A. E.
Armellin C.
Arredondo Saldana G.
Astl J.
Athanasakis E.
Avenia S.
Aydin H.
Azaryan I.
Baba B.
Babala J.
Bains L.
Banus M. V.
Barba-Valadez L. A.
Barcons S. V.
Basili G.
Battafarano F.
Bayat A.
Bella R. M. C.
Benariba F.
Bernardi S.
Bignami E. G.
Bitenc M.
Bitsianis S.
Bolanos de la Torre J. D. D.
Bolukbasi H.
Bonati E.
Bonetti T.
Bononi M.
Borges F. A.
Borumandi F.
Bouchagier K.
Boudina M.
Bourial A.
Bozan M. B.
Brenta G.
Breuskin I.
Brock P.
Brunaud L.
Brunner M.
Bruns C.
Buemi A.
Burlacu M. C.
Burton T.
Buta M.
Buzanakov D.
Caliseo C.
Callanan D.
Calo P. G.
Calu V.
Cameselle-Teijeiro J. M.
Camilo-Junior D. J.
Canberk S.
Candalise V.
Candanedo-Gonzalez F.
Canu G. L.
Cappellacci F.
Carrillo Lizarazo L. J.
Cartwright S. B.
Carvalho G. B.
Casallas D.
Casolino C.
Castellani L.
Castells Fuste I.
Castillo Morales C.
Cavalheiro B.
Cavallaro G.
Chala A.
Chambon G.
Chan S. Y. B.
Chaplin J.
Chatzipavlidou V.
Cheema M. S.
Chernikov R.
Chiapponi C.
Chiofalo M. G.
Chorti A.
Chow T. C. M.
Chrisoulidou A.
Chrysos E.
Chrysos E.
Conrado-Neto S.
Cordova Garcia D.
Corigliano A.
Crocco A.
Cuesta A.
Cukman M.
Curto L. S.
D'Amore A.
D'Anna R.
D'Orazi V.
Damilano R. A.
de Cillia M.
De Crea C.
De M.
de Manzini N.
de Matos L. L.
De Pasquale L.
De Virgilio A.
Del Rio P.
Dellaportas D.
Demarchi M. S.
Demarquet L.
Devresse A.
Dhiwakar M.
Di Meo G.
Diaz Pedrero R.
Dimitrov D.
Dmitry Z.
Dobrinja C.
Dominguez Garijo P.
Donatini G.
Dora J. M.
Doulatram Gamgaram V. K.
Dulgeroglu O.
Dural A. C.
Eismontas V.
Eksi A.
El Hammoumi M.
El Kaoui H.
El Malki H. O.
Eleni G.
Elliyanti A.
Elzahaby I.
Enciu O.
Ersoz
Escobar-Jimenez M.
Eskander A.
Fedorova L.
Feeley L.
Fernandez Rodriguez E.
Feroci F.
Ferreli F.
Figueroa-Bohorquez D.
Filis D.
Filoia A.
Fingeret A.
Francescato A.
Francois G.
Frias-Fernandez P.
Gaino F.
Galiandro F.
Gallegos-Hernandez J. F.
Gamboa-Dominguez A.
Garas G.
Garcia Lorenzo F.
Garcia-Chavez J. P.
Gaudiello M.
Gay S.
Genc V.
Gerasimos S.
Gerek M.
Gervasi R.
Giordano A.
Giordano D.
Gjeloshi B.
Gocky L.
Golubinskaya E.
Gomez-Pedraza A.
Gonzalez Romero S.
Gonzalez-Minguez C.
Goran M.
Gosman A.
Graceffa G.
Granados Garcia M.
Greco E.
Griffin J.
Grunbart M.
Grutzmann R.
Guerlain J.
Guerreiro S. C.
Guirao X. G.
Gupta K.
Gupta K. K.
Gurrado A.
Guzey D.
Hajiioannou J.
Hajjij A.
Hakala T.
Hamdy O.
Hameed M. S.
Harahap W. A.
Hargitai L.
Hartl D.
Hauth L. A.
Hellmann A.
Hernandez-Acevedo J. D.
Hernandez-Carrillo J. F.
Hevilla Sanchez F.
Hlozek J.
Hoang V. T.
Hoi H.
Hongkwon K.
Hu Zhu R.
Huang E.
Hyeung Kyoo K.
Iacobone M.
Ignjatovic V.
Innaro N.
Ioannidis A.
Ioannidis O.
Iossa A.
Isik A.
James D.
Jang J. H. I.
Jovanovic M.
Jung Hoon L.
Kabiri E. H.
Kaderli R. M.
Kakamad F.
Kaliszewski K.
Kara H.
Karajovic J.
Karamanliev M.
Kartini D.
Katoh H.
Khambri D.
Kholova I.
Kim S. Y.
Kisiel M.
Knezevic M.
Koh Y. Q.
Konca C.
Kosec A.
Kosmidis C.
Kotsovolis G.
Kovacevic B.
Kowalski L. P.
Kowalski L. P.
Kralik R.
Kralik R.
Kuczma P.
Kumorova A.
Kuravi B. G.
Kurnia A.
Kyriaki V.
Lai C. M.
Lallemant B.
Lampridis S.
Lardhi A. A.
Lasithiotakis K.
Leboulleux S.
Leclere J. -C.
Lee J. W.
Lelli G.
Leong E. K. F.
Leow M. K. -S.
Leutner M.
Lim C. M.
Lim J. Y.
Lim M. Y.
Lino-Silva L. S.
Liu S. Y. W.
Llanos A.
Llorach N. P.
Lo X.
Loderer T.
Lombardi C. P.
Lopez-Corrales M. A.
Lopez-Gomez J.
Lori E.
Lucchini R.
Ludwig M.
Madani A.
Magnabosco F. F.
Maheo C.
Maia A. L.
Makay O.
Maksimova P.
Mallick S.
Mallouk C.
Mamani Z.
Manatakis D.
Mandal S.
Manyalich Blasi M.
Marincola G.
Markovic I.
Marulanda M.
Materazzi G.
Mavromati M.
Mayilvaganan S.
Mazeh H.
Medas F.
Mercante G.
Metso S.
Meyer-Rochow G. Y.
Micalizzi A.
Michalopoulos A.
Mihaljevic O.
Miller J. A.
Min-Su K.
Minuto M.
Miron A.
Mishra A. K.
Misso C.
Mittermair C.
Monacelli M.
Morosan Allo Y.
Mourad M.
Moysidis M.
Mulita F.
Mullineris B.
Munoz-de-Nova J. L.
Muradas Girardi F.
Nabhan F.
Nader S.
Napadon T.
Nasiri R.
Nastos C.
Nastos C.
Ngiam K. Y.
Nomine-Criqui C.
Ntziovara A. M.
Nuno Vazquez-Garza J. M.
Nutautiene V.
O'Keeffe L.
Obtulovicova K.
Offi C.
Okudur N. O.
Oragano L.
Orois A.
Ossola P.
Ovejero Merino E.
Ozdemir M.
Pan Y.
Panagiotidis E.
Panchangam R. B.
Pangonis A.
Panigoro S. S.
Panuzi A.
Papaconstantinou D.
Papavramidis T.
Pardo Matamoros N.
Parida P. K.
Paschou S.
Pasculli A.
Paspala A.
Paterakis K.
Peiris K.
Pennestri F.
Peppa M.
Perdikaris I.
Perdikaris P.
Perez O. V.
Perez-Soto R. H.
Petrovic S.
Piana S.
Piccoli M.
Pietrasanta D.
Placentino G.
Pliakos I.
Polistena A.
Pongtippan A.
Potard G.
Quinn V.
Quintanilla-Dieck L.
Raffaelli M.
Rahul P.
Ramacciotti C. F.
Ramos T.
Rankin A.
Ratia Gimenez T.
Ratnayake P.
Reuto-Castillo J.
Ridolfo A.
Rios-Valencia J.
Riss P.
Rival E.
Rivillas J.
Rivo Vazquez A.
Roh J. -L.
Roi D.
Rollo E. M.
Romanchishen A.
Romito M.
Ronen O.
Rossi L.
Rotnagl J.
Rovcanin B.
Russo G.
Sabol M.
Saki S.
Saleh S.
Salih A.
Saltiki A.
Salvador-Camarmo G.
Samal D. K.
Sanabria A.
Sanchez-Flores S.
Santeerapharp A.
Sapalidis K.
Sarin D.
Sarin H.
Savkovic N.
Scheffel R. S.
Scheinpflug A. L.
Scheuba C.
Scheyer N.
Schmidt M.
Semenov A.
Senashova O.
Seneviratne S.
Serafini E.
Serdar A.
Serrano Arevalo M. L.
Shank J.
Sheahan P.
Sheppard S. C.
Shindo M. L.
Shoshkova M.
Shvan M.
Sicak M.
Silva T. G.
Simo Guerrero O.
Skuletic V.
Slijepcevic N.
Slotcavage R. L.
Slovic Z.
Smaxwil C.
Soares P.
Somova A.
Sorrenti S.
Soto S.
Spartalis E.
Spiezia S.
Sriphrapradang C.
Stankovic V.
Stephenson K. J.
Straub E.
Summa M.
Surani S.
Syed A. A.
Symeonidis S.
Taciak A.
Tarallo M.
Tarle A.
Tasis N.
Tausanovic K.
Tchabashvili L.
Testini M.
Thierry M.
Tokarczyk U.
Toma E. A.
Topuz S.
Torresan F.
Turk Y.
Tzikos G.
Uras C.
Vabalayte K.
Vaccaro C.
Valdes de Anca A.
Valentini M.
Varaldo E.
Vargas-Osorio K.
Vartanian J. G.
Vazquez Renteria R. S.
Velazquez-Fernandez D.
Verras G. I.
Vithana S. M. P.
Vithanage A.
Wijayalathge H.
Wiriyaamornchai P.
Wong Y. L. C.
Wongwattana P.
Xavier-Junior J. C.
Xenaki S.
Xie S.
Xu M.
Yadav S. K.
Yang W.
Yilmaz S.
Yilmaz Y. F.
Yotsov T.
Yucel L.
Yulian E. D.
Zahid M. T.
Zahradnikova P.
Zarogoulidis P.
Ziablitskaia E.
Zielke A.
Zolotoukho A.
Publication venue: ELSEVIER SCIENCE INC
Publication date: 28/04/2023
Field of study

Background Since its outbreak in early 2020, the COVID-19 pandemic has diverted resources from non-urgent and elective procedures, leading to diagnosis and treatment delays, with an increased number of neoplasms at advanced stages worldwide. The aims of this study were to quantify the reduction in surgical activity for indeterminate thyroid nodules during the COVID-19 pandemic; and to evaluate whether delays in surgery led to an increased occurrence of aggressive tumours.Methods In this retrospective, international, cross-sectional study, centres were invited to participate in June 22, 2022; each centre joining the study was asked to provide data from medical records on all surgical thyroidectomies consecutively performed from Jan 1, 2019, to Dec 31, 2021. Patients with indeterminate thyroid nodules were divided into three groups according to when they underwent surgery: from Jan 1, 2019, to Feb 29, 2020 (global prepandemic phase), from March 1, 2020, to May 31, 2021 (pandemic escalation phase), and from June 1 to Dec 31, 2021 (pandemic decrease phase). The main outcomes were, for each phase, the number of surgeries for indeterminate thyroid nodules, and in patients with a postoperative diagnosis of thyroid cancers, the occurrence of tumours larger than 10 mm, extrathyroidal extension, lymph node metastases, vascular invasion, distant metastases, and tumours at high risk of structural disease recurrence. Univariate analysis was used to compare the probability of aggressive thyroid features between the first and third study phases. The study was registered on ClinicalTrials.gov, NCT05178186.Findings Data from 157 centres (n=49 countries) on 87 467 patients who underwent surgery for benign and malignant thyroid disease were collected, of whom 22 974 patients (18 052 [78 center dot 6%] female patients and 4922 [21 center dot 4%] male patients) received surgery for indeterminate thyroid nodules. We observed a significant reduction in surgery for indeterminate thyroid nodules during the pandemic escalation phase (median monthly surgeries per centre, 1 center dot 4 [IQR 0 center dot 6-3 center dot 4]) compared with the prepandemic phase (2 center dot 0 [0 center dot 9-3 center dot 7]; p<0 center dot 0001) and pandemic decrease phase (2 center dot 3 [1 center dot 0-5 center dot 0]; p<0 center dot 0001). Compared with the prepandemic phase, in the pandemic decrease phase we observed an increased occurrence of thyroid tumours larger than 10 mm (2554 [69 center dot 0%] of 3704 vs 1515 [71 center dot 5%] of 2119; OR 1 center dot 1 [95% CI 1 center dot 0-1 center dot 3]; p=0 center dot 042), lymph node metastases (343 [9 center dot 3%] vs 264 [12 center dot 5%]; OR 1 center dot 4 [1 center dot 2-1 center dot 7]; p=0 center dot 0001), and tumours at high risk of structural disease recurrence (203 [5 center dot 7%] of 3584 vs 155 [7 center dot 7%] of 2006; OR 1 center dot 4 [1 center dot 1-1 center dot 7]; p=0 center dot 0039).Interpretation Our study suggests that the reduction in surgical activity for indeterminate thyroid nodules during the COVID-19 pandemic period could have led to an increased occurrence of aggressive thyroid tumours. However, other compelling hypotheses, including increased selection of patients with aggressive malignancies during this period, should be considered. We suggest that surgery for indeterminate thyroid nodules should no longer be postponed even in future instances of pandemic escalation.Funding None.Copyright (c) 2023 Published by Elsevier Ltd. All rights reserved

Archivio istituzionale della ricerca - Università di Palermo

Timing of nasogastric tube insertion and the risk of postoperative pneumonia: an international, prospective cohort study

Author: 't Hart E.
Aabling R. R.
Aarts C. A. M.
Aba M.
Abad-Motos A.
Abbasguliyev H.
Abdelgalil R.
Abdelhameed F.
Abdulrahman N.
Abdulrahman S. M. F.
Abdulrahman Z.
Abelevich A.
Abello D.
Ablett A. D.
Ablett A. D.
Abrisqueta J.
Acherman Y. I. Z.
Adam A. H.
Adamo V.
Adams S. I. B.
Adel A.
Adeleye O.
Adeusi L.
Adiyaman C.
Adra M.
Afsar H. B.
Aftab R.
Agarwal A.
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Agca M. H.
Aggiusti A.
Agresta F.
Aguilar-Martinez M. M.
Aguilera M. L.
Aguilera M. L.
Aguilera M. L.
Ahmad H.
Ahmed A.
Ahmed H.
Ahmed K.
Ahmed M.
Ahmed M.
Ahmed S.
Ahmed S.
Ahmed W. U. R.
Ahmeidat A.
Ahsan S. D.
Ainsworth P.
Aitken E.
Aitken G.
Ajmera A.
Akay F. E.
Akbani U.
Akbar Z.
Akbari K.
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Publication venue
Publication date: 01/01/2020
Field of study

Aim: Aspiration is a common cause of pneumonia in patients with postoperative ileus. Insertion of a nasogastric tube (NGT) is often performed, but this can be distressing. The aim of this study was to determine whether the timing of NGT insertion after surgery (before versus after vomiting) was associated with reduced rates of pneumonia in patients undergoing elective colorectal surgery. Method: This was a preplanned secondary analysis of a multicentre, prospective cohort study. Patients undergoing elective colorectal surgery between January 2018 and April 2018 were eligible. Those receiving a NGT were divided into three groups, based on the timing of the insertion: routine NGT (inserted at the time of surgery), prophylactic NGT (inserted after surgery but before vomiting) and reactive NGT (inserted after surgery and after vomiting). The primary outcome was the development of pneumonia within 30 days of surgery, which was compared between the prophylactic and reactive NGT groups using multivariable regression analysis. Results: A total of 4715 patients were included in the analysis and 1536 (32.6%) received a NGT. These were classified as routine in 926 (60.3%), reactive in 461 (30.0%) and prophylactic in 149 (9.7%). Two hundred patients (4.2%) developed pneumonia (no NGT 2.7%; routine NGT 5.2%; reactive NGT 10.6%; prophylactic NGT 11.4%). After adjustment for confounding factors, no significant difference in pneumonia rates was detected between the prophylactic and reactive NGT groups (odds ratio 1.03, 95% CI 0.56–1.87, P = 0.932). Conclusion: In patients who required the insertion of a NGT after surgery, prophylactic insertion was not associated with fewer cases of pneumonia within 30 days of surgery compared with reactive insertion

Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli"

Safety of hospital discharge before return of bowel function after elective colorectal surgery

Author: Aabling R. R.
Aba M.
Abad-Motos A.
Abbasguliyev H.
Abdelgalil R.
Abdelhameed F.
Abdulrahman N.
Abdulrahman S. M. F.
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Abelevich A.
Abello D.
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Publication venue: 'Wiley'
Publication date: 01/01/2020
Field of study

Background: Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function. Methods: A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien–Dindo classification system. Results: A total of 3288 patients were included in the analysis, of whom 301 (9·2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4–7) and 7 (6–8) days respectively (P < 0·001). There were no significant differences in rates of readmission between these groups (6·6 versus 8·0 per cent; P = 0·499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0·90, 95 per cent c.i. 0·55 to 1·46; P = 0·659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34·7 versus 39·5 per cent; major 3·3 versus 3·4 per cent; P = 0·110). Conclusion: Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients

Archivio istituzionale della ricerca - Università dell'Insubria

Archivio istituzionale della ricerca - Università di Bari

Archivio istituzionale della ricerca - Università di Cagliari

Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli"

IRIS Università degli Studi dell'Aquila

Archivio istituzionale della ricerca - Università di Padova

Archivio Istituzionale della Ricerca- Università del Salento

Archivio istituzionale della ricerca - Università di Palermo

Archivio della ricerca - Università degli studi di Napoli Federico II

AIR Universita degli studi di Milano

Archivio della Ricerca - Università degli Studi di Siena

Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna

PORTO@iris (Publications Open Repository TOrino - Politecnico di Torino)

Archivio della ricerca- Università di Roma La Sapienza

Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

Author: A A B Wyche
A A Francis
A A Francis
A A W Geloven
A Abelevich
A Adel
A Agarwal
A Aggiusti
A Ahmed
A Ahmeidat
A Ajmera
A Akisheva
A Al-Azzawi
A Al-hadithi
A Al-Salihi
A Alagoa João
A Alagoa João
A Aldarragi
A Ali
A Ali
A Alsaif
A Alshakhs
A Amado
A Amico
A Armellini
A Arnold
A Asif
A Asif
A Atiyah
A Aversano
A B Aksoy
A B Teasdale
A Badran
A Badran
A Barberis
A Bareh
A Barina
A Barkovskaya
A Barrett
A Bartnick
A Bartoli
A Basak
A Batista
A Batterham
A Begaj
A Belli
A Belli
A Benevento
A Bettella
A Bhargava
A Biancafarina
A Biancafarina
A Birindelli
A Birindelli
A Bondurri
A Borakati
A Borakati
A Borisova
A Borisova
A Boulbadaoui
A Brescia
A Brodie
A Bugmann
A Burzic
A Busuttil
A C Aru
A C Bilgili
A C Pedersen
A C Quintela
A Caiazzo
A Campbell
A Campbell
A Campbell
A Capozzolo
A Casaril
A Chan
A Charalabopoulos
A Charalambous
A Chiang
A Chrimes
A Chuang
A Clavé Llavall
A Clucas
A Coomes
A Couldrey
A Cruccu
A Cruz
A Cutler
A D Ablett
A D Ablett
A D Antona
A D Cevlik
A Dawson
A Dawson
A Debiasio
A Dharni
A Di Cintio
A Dias Matos
A Drane
A Dulskas
A Dworkin
A E Isik
A Elbayouk
A Emin
A F Rocha
A Fares Bucci
A Faustino
A Fontani
A Foulkes
A Franceschi
A Franceschi
A Fung
A G Marrosu
A G Silva
A Gabarski
A Gadhvi
A Galgano
A Garcia
A Gavrilina
A Gemini
A Gennai
A Gharooni
A Ghosh
A Giani
A Giannella
A Gibbins
A Gilliam
A Giri
A Goede
A Gopaul
A Gordon
A Gori
A Grüter
A Guerreiro
A Guglielmi
A Guner
A Güldag
A H Adam
A H Dyer
A H W Ven
A Haji
A Henkens
A Herd
A Heybourne
A Hickman
A Hogan
A Hogan
A Hotchkies
A Huot
A Hylands
A Ibrahim
A Ioannidis
A Ioannidis
A Ipor
A Isabello
A Isik
A Izzarina
A Jackson
A Jacobson
A Jain
A James
A Jones
A Joseph
A Jovaisaite
A K Aly
A Kanitkar
A Karabulut
A Kechagias
A Kechagias
A Kechagias
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A Kelliher
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A Khanan Kaabneh
A Kilinç
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A Kopp
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A Kushairi
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A M Seckler
A M Wiemann
A Machado
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J Ng
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J Tan
J Tan
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J Wong
J Wong
J Wong
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J Y Kok
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J Örhalmi
K Ahmed
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N Yu
N Zulkefley
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O Adeleye
O Alhalabi
O Aliosin
O Aromolaran
O Awokoya
O Bauermeister Potts
O Biyiklioglu
O Blackwood
O C Veen
O Cheng
O Costigan
O Dixon
O F Kuyumcu
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O Hall
O Holman
O Houdek
O J Wadsworth
O Jones
O Kirnon-Jackman
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O Milliet
O Morice
O O Onafowokan
O Ojofeitimi
O Oke
O Page
O Pittet
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O Wright
P A G Bisagni
P A Kasar
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Q J Tan
Q X Lim
R A Khaw
R A Schasfoort
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Rebecca Gorgievska
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V Murray
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V Nevoso
V Neykov
V Neykov
V Nutautiene
V Ozben
V P Geneta
V Paixão
V Panizzo
V Papagni
V Patel
V Pavlov
V Pedro
V Poponesi
V Praxedes
V Prochazka
V Ripetti
V Ripetti
V Schaeff
V Schaeff
V Schaeff
V Taranu
V Testa
V Testa
V Thakrar
V Thirugnanasundralingam
V Tonini
V Udayachandran
V V Ćuk
V V Ćuk
V Vyas
W A Bemelman
W Beedham
W Clay
W Fleischl
W Fordyce
W Fradley
W J English
W J Owen
W K Lau
W Lam
W Mculu
W Perchard
W Pyc
W Pyc
W Reynolds
W S Ngu
W Saleh
W Simpson
W Sloper
W Sloper
W Thomson
W U R Ahmed
W Wynell-Mayow
X Sousa
Y Ali
Y Bei
Y Bekker
Y Bhahirathan
Y Bhahirathan
Y Bharwada
Y Chechelnitskaya
Y D Lee
Y Demiroglu
Y E Alim
Y E Aytin
Y E Karapinar
Y Embury-Young
Y Gercek
Y I Z Acherman
Y J Alame
Y J Lee
Y J Soh
Y K Goh
Y K Lim
Y Karaman
Y Kaya
Y Kaya
Y L Pang
Y L Wang
Y Li
Y M Tissen
Y Mahmoudi
Y Majeed
Y Mitkov
Y N Goh
Y Nikookam
Y Q Yeo
Y Qamar
Y Shafiq
Y Toyi
Y Vroom
Y Xiao
Y Youssef
Y Z Beh
Z Abdulrahman
Z Akbar
Z Al-Saraff
Z Al-Sarraf
Z Ali
Z B Koçak
Z Ballarini
Z Carrington
Z Garoufalia
Z Goolam-Mahomed
Z H Sam
Z Habib
Z Iqbal
Z Millar
Z Ngwenya
Z Noriega
Z S Demirci
Z Sheikh
Z Xuan Tan
Z Y Boh
Z Yi Tew
Z Yi Tew
Z Yusuf
Çagri Girit
é Dockry
Ö Kürklü
Ö Uslu
Ö Uslu
Ö Yumurtaci
Publication venue: Oxford University Press (OUP)
Publication date: 09/10/2019
Field of study

Abstract Background Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery. Methods A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a centre-specific survey of compliance to enhanced recovery principles. Secondary safety outcomes included anastomotic leak rate and acute kidney injury. Results A total of 4164 patients were included, with a median age of 68 (i.q.r. 57–75) years (54·9 per cent men). Some 1153 (27·7 per cent) received NSAIDs on postoperative days 1–3, of whom 1061 (92·0 per cent) received non-selective cyclo-oxygenase inhibitors. After adjustment for baseline differences, the mean time to gastrointestinal recovery did not differ significantly between patients who received NSAIDs and those who did not (4·6 versus 4·8 days; hazard ratio 1·04, 95 per cent c.i. 0·96 to 1·12; P = 0·360). There were no significant differences in anastomotic leak rate (5·4 versus 4·6 per cent; P = 0·349) or acute kidney injury (14·3 versus 13·8 per cent; P = 0·666) between the groups. Significantly fewer patients receiving NSAIDs required strong opioid analgesia (35·3 versus 56·7 per cent; P &lt; 0·001). Conclusion NSAIDs did not reduce the time for gastrointestinal recovery after colorectal surgery, but they were safe and associated with reduced postoperative opioid requirement. </jats:sec

Crossref

Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

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Imadalou L
Imam L
Impellizzeri H
Impellizzeri H
Imperatore M
Imtiaz M
Inama M
Incollingo P
Ioannidis A
Ioannidis A
Ipor A
Iqbal R
Iqbal Z
Irwin E
Isabello A
Isik A
Isik A E
Isik K
Iskan N G
Isler V C
Isse M
Ivanov T
Ivanov V
Ivanov V
Izzarina A
İşlek E C
Jackson A
Jackson L
Jacobson A
Jaffer T
Jaich R
Jaich R
Jain A
Jain C
Jakubauskas M
Jakubauskas M
Jamal M
James A
James C
James P
James P
James S J
Janković U
Janmohamed I
Jardim J A M
Jarrar G
Jasionowska S
Jasionowska S
Jayalath J M S N
Jeddy H
Jeffrey E
Jegathees T
Jegatheeswaran L
Jelovskis I
Jenkins B
Jense M T F
Jeong S
Jepsen B N
Jervis M J
Jimulia D
Jirankova K
Jobson J
Johnson M
Johnson N
Johnson T A
Johnston J
Jones A
Jones C J
Jones D
Jones J
Jones M R
Jones N
Jones O
Jonge J
Jordão D M
Joseph A
Joseph N
Joshi N
Jotautas V
Jovaisaite A
Jovanović M
Jozaf V
Juloski J
Juloski J
Jun H J S
Jung M
Juniper S
Jurgaitis J
Jürgens-Lahnstein J
Kader T
Kakar S
Kakodkar P
Kalderon R
Kalderon R
Kalles V
Kamarajah S
Kamath P J
Kamel F
Kan P
Kandelaki H
Kane R
Kang C K
Kang S J
Kanitkar A
Kara H
Kara M
Karabulut A
Karabulut K
Karagöz E
Karakus K
Karaman Y
Karamanliev M
Karamanliev M
Karampinis I
Karanikas I
Karapinar Y E
Karelia S
Kargici K
Karip B
Kasar P A
Katunin J
Kavaliauskaite R
Kavaliauskas P
Kavar R C
Kaya M
Kaya Y
Kaya Y
Kayacan S
Kearney J
Keating R
Kechagias A
Kechagias A
Kechagias A
Kefleyesus A
Kelk L
Kelliher A
Kelly B
Kenny R
Ker H
Kerckhoffs P
Kerem C
Kerimzade K
Keskin M
Khadka P
Khalid N
Khalil M
Khan A
Khan H
Khan H
Khan K
Khan M
Khan S
Khan S M
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Khaw R A
Khera G
Khera R
Khogali E
Khor S
Khosla S
Khoury G
Kiandee M
Kilgallon E
Kilic V
Kilinc I
Kilinç A
Kilpatrick K
Kim D H
Kind C
Kip M
Kiraz I N
Kirk S
Kirnon-Jackman O
Kirupananthan P
Kisiel A
Kisiel A
Kjaer M D
Kjaer M D
Klail T
Kler A
Knight J
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Knowles C H
Ko M
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Koh S
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Kolev N
Kološová B
Komolafe O
Konstantinidis K M
Konstantinidis M
Konstantinidis M
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Kopp A
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Korkolis D
Kouli O
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Kovacevic M
Kowal M
Kowal M
Köseoglu E
Kraria L
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Kristensen F P
Kruger C
Krupp J
KryŽauskas M
Kubolli I
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Kudva V
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Kulathevanayagam K
Kulendrarajah B
Kuliavas J
Kumar A
Kunčarová K
Kunčarová K
Kungwengwe G
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Kurtoglu G K
Kus D
Kushairi A
Kutlu B
Kutluk F
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Kürklü Ö
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Kwek I
Kwek I
Kwok K
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Kybransiene M
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Ladak N
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Lai L T
Lal R
Lam S
Lam W
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Lanari J
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Langenhoff B
Lapolla P
Lapsa S
Laquatra N
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Larcinese A
Larkin J
Larnovskis J
Larsen H M
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Latter M
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Lau W K
Laurence N
Lauretta A
Lauretta A
Laverty L
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Lawday S
Lawther J
Lazzarini E
Leaning M
Leathes J
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Lecler J
Lee D E
Lee H J
Lee H J
Lee J
Lee J
Lee L
Lee S
Lee Y D
Lee Y J
Leeuwen B L
Lehmann J
Leite M
Lely S J
LeNaoures P
Lencastre L
Lennock S
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Lessware T
Leung S P
Leventoglu S
Lewis D
Lewis E
Lewis F
Lewsey J
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Li E
Li Y
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Libri I
Licari L
Liebenberg P
Liebenberg P
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Lim J
Lim Q X
Lim Y K
Lima R
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Lindwe S
Ling E
Ling J J
Linn T
Litvin A
Litvin A
Liu B
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Liu F Y
Liversedge G
Livie J
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lo Conte A
Loche G A
Locke S
Lockwood S
Loeve U S
Logue G
Loizidou A
Longheu A
Longshaw A
Looyen R
Lopes N M R O
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Lorettu A
Lou G
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Louro H
Louro T
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Lovisetto F
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Lucchi A
Ludvik M
Luglio G
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Luong J K
Lutovinova E
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Ly J
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Lycke K D
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Lyulenina E
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Macgregor L
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Maciaszek M
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Maciel J
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Mackee L
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Magnoli M
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Malerba M
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Manigrasso M
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Mansoor M
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Marcianò M
Marco M
Marcocci G
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Marra E
Marrosu A G
Marshall K
Martensen A
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Marx M
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Maskill L
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Mclean K
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McTiernan M
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Miranda P
Mirza S
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Mistrangelo M
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Mladenov T
Modi S
Moehwald C
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Moggia E
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Mohammed N
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Molder L
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Molteni B
Molteni B
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Monks M
Montanelli P
Monteiro C
Monteiro C
Monteiro N
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Montwedi D
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Moore T
Moosa A
Mora A
Morais S
Morales M
Moreira M
Moretto G
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Morreau M
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Muir K
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Mullarkey L
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Mura G A
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Murray M
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Muthukumar M G
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Nicola M
Nicolaides A
Nielsen C V
Nieuwenhuizen S
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Nirmalanantha A
Niskakangas M
Njoku P
Noriega Z
Norman J G
Norwood M
Nossier R
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Nshalati Salvation M
Ntakomyti E
null null
null null
null null
Nur A
Nutautiene V
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O'Callaghan H
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O'Gorman D
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O'Neill D
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Obukofe R
Obukofe R
Odovic M
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Ojofeitimi O
Oke O
Olawi F
Oliphant R
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Oliveira J
Oliveira N
Oliveira S
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Olivieri M
Omundsen M
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Ong H I
Ong L
Ongaro D
Onur E
Orbell J
Orekoya M
Orelhas L
Ortenzi M
Osborn G
Osborne C
Osunronbi T
Otto A
Otto A
Otto A
Ottonello R
Ourô S
Owen M
Owen M
Owen W J
Oyebola T
Oyomno M
Ozbalci G S
Ozben V
Ozkan B B
Ozmen B B
Ozoglu F
Ozolins A
Ölmez M
Önsal U
Örhalmi J
Örhalmi J
Özbek M
Özen D
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Pacheco A
Paclík A
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Pagano G
Page O
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Palkhi A
Palmer A
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Palmer C
Panaccio P
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Pandya A
Pang Y L
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Paolucci A
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Papandrea M
Papanikolaou A
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Parekh J N
Parini D
Parini D
Parisi A
Parker D
Parmar S
Parnell J
Parreira R
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Pascoe R
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Pasquali S
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Pata F
Pata F
Pata G
Pata G
Pata P
Patel M
Patel N
Patel P
Patel S
Patel V
Pathak S
Patil P
Patrawala S
Patrício J
Patrocinio S
Paul M
Pavlov V
Pawa N
Paycheva T
Pazzona M
Peckham H
Peddis M
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Pedrazzani C
Pedro V
Pehlivan M
Peixoto R
Pektas A M
Pellegrino L
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Pellino G
Pellino G
Pellino G
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Peng S L
Peng S L
Penningnieuwland G
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Pentti E
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Perchard W
Percivale A
Pereira F
Pereira J
Pereira M
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Perrone B A
Perrone G
Perrone G
Persiani R
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Petrelli F
Petrulionis M
Peyroteo M
Peyroteo M
Pham H D V
Pherwani S A
Philip Rajathasan T
Phillips J
Phillips S
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Piazza G
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Picciariello A
Picciariello A
Piccolo G
Picone E
Pieri K
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Pietroletti R
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Pike S
Pillai S
Pilotta F
Pimentel A
Pina S
Pinkney T
Pintabona G
Piong C L
Piotet L M
Piozzi G N
Piozzi G N
Piperidis A
Pipitone Federico N S
Pipitone Federico N S
Piras K
Pirillo M
Pitt J
Pittet O
Piya S
Pockney P
Pockney P
Podda F
Podda M
Podda M
Podda M
Poelman M
Poggioli G
Pohl L J
Pohl L J
Poillucci G
Poli F
Polson R
Poncelet A
Ponomarev N
Pool A
Pooley G
Popescu S
Popescu S
Popescu S S
Poponesi V
Portelli L
Portelli L
Poskus T
Pospíšil M
Poškus E
Poškus T
Poustie M
Poustie M
Povey M
Powell J
Powell T
Powell-Chandler A
Powell-Chandler A
Pös M
Praag E M
Pratas N
Praxedes V
Prem M
Procacci P
Prochazka V
Prodromidou A
Profita G
Provenza G
Pruijssers S R
Pruijssers S R
Psaila J
Puchalski N
Puglisi S
Puleo S
Pulickal P
Pulighe F
Pullybank A
Puri G
Pyc W
Pyc W
Qamar Y
Quattromani R
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Quinn P
Quinn P
Quintela A C
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Radcliffe K
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Radulović R
Ragavoodoo A
Ragavoodoo A
Rahi M
Rahman A
Rai P
Raimondo S
Rainey M
Rais A
Rajaraman N
Rajendran K
Rajput K
Ralston C
Ramanayake H
Rambhatla S
Ramdin A
Ramjeeawon A
Ramos L
Ramsay G
Ramwell A
Rana N
Rankin A
Ransome M
Raos M
Rashid A
Rassool S B
Ratnasingham D
Rausei S
Ravn S
Rawat N
Raymond T
Rädeker L
Realis Luc A
Rebuffa N
Redclift C
Reddy A
Redmond J
Rees J
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Rega D
Rega D
Reggiani L
Rehman S
Reia M
Reid F
Reilly S
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Rettaroli C
Reveendran D
Reynolds L
Reynolds W
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Ribeiro A
Ribeiro H
Ribeiro J
Riccardi M
Ricciardiello M
Richards T
Richardson E T J
Richardson S
Ricolleau C
Ridgway P F
Ridgway S
Ridwan R
Riordan E
Ripetti V
Ripetti V
Riško J
Riško J
Robb P M
Robinson A V
Rocha A F
Rocha B S
Rocha-Melo M
Roche C D
Rodriguez J
Roggiani A
Rojoa D
Rojoa D M
Romaen I
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Romano J
Romano M
Romano M
Romano S
Romanova E
Romelli M
Romeo G
Romoli L
Ronconi M
Rondelli F
Rosales J
Rosati R
Roseira J
Rosete M
Rosete M
Ross C
Ross T
Rotimi O
Rotolo G
Rottier S J
Roxburgh C
Roy van Zuidewijn D
Rshaidat H
Ruddy C M
Ruggieri A
Ruggiero S
Ruggiu G V
Ruggiu M W
Ruiter A
Ruparelia A
Ruppeldt P
Russell C
Russell C
Ruzzenente A
Rye D S
Rylance A
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Sahin C
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Sait S
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Saiyed A
Salamone G
Salaris C
Saleh R
Saleh S
Saleh W
Salibasic M
Salman M
Saluja T
Salvadori R
Sam Z H
Samake M
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Samee A
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Sammour T
Sammut K
Sammut M
Sampietro G
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Sancini G
Sanders-Crook L
Sandhu N
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Sanna S
Santangelo M
Santos J
Santos M
Santos M
Santos T C
Santullo F
Sanyal S
Sapre D
Saraiva P
Saraiva R
Sardiwalla I
Sarfraz N
Sariçiçek T
Sarıgül L
Sartaj F
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Sasia D
Satilmisoglu M
Sauka J
Saunders M
Sautter S C
Sauvain M O
Savchenko A
Savino G
Savino G
Saxena A
Sá T C
Scanlon K
Scaramuzzo R
Schachtel M
Schaeff V
Schaeff V
Schaeff V
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Schofield R
Schöning L
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Scott A
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Segalini E
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Sgrò A
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Sharma S
Sharriff H
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Sheldon J
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Shishkin B
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Shortland T C
Shoshkova M
Shrestha S
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Silva F
Silva M
Silva R
Silva-Vaz P
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Simcikas D
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Simioni A
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Simões J
Simpson W
Singh A
Singh B
Singh N
Sinha S
Sinibaldi G
Sinibaldi G
Sisley M
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Sivarajah S
Sivinš A
Skalický A
Skalický P
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Skan O
Skavysh A
Skejø C D
Skipworth C
Skull A
Slepavicius A
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Slooter G
Sloper W
Sloper W
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Smaalen T C
Smart N J
Smillie R
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Smith D
Smith E
Smith F M
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Soares D
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Soh Y J
Solomou G
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Soman S
Sookramanien S R
Sotona O
Sousa D
Sousa M
Sousa X
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Spinty J
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Spyrou I
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Stahl R
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Stanfield B
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Steinle J
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Stellingwerf M E
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Stercz M
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Stewart P
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Storm M
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Stroud R
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Stubbs B
Stylianides N
Subramanian I
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Suchdev N
Suchett-Kay I
Suchett-Kaye I
Sunal A
Sunay A O
Suresan S
Suresh G
Suresh G
Surgo D
Swamad M
Syed L
Sysum K
Sørensen J S
šuta Kimle K
Tabibi M
Taglietti L
Talamo G
Talamo G
Taleongpong P
Tam H
Tam J P H
Tam J P H
Tam L Y C
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Tamini N
Tammaro N
Tamosiunas A
Tan H L
Tan I X H
Tan J
Tan J
Tan K
Tan Q J
Tan R
Tan R R
Tan T K
Tandon R
Taneja S
Tang A
Tanvir T
Taranu V
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Taylor M
Taylor N
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Teeling F
Teh J S
Teixeira H
Telford K
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Testa V
Testa V
Tewhaiti-Smith J
Thakkar R
Thakral N
Thakrar C
Thakrar C
Thakrar V
Thavayogan R
Thavayogan R
Thäwel T
Theocharidou L
Theodoraki G
Theodoropoulou K
Thirugnanasundralingam V
Thomas D A
Thomas G
Thomas P
Thomas S
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Thompson C
Thompson E
Thomson W
Thorn C
Thornton M
Tie-Gill T
Tiftik E
Tiftik E
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Timms S
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Tulek M S
Tuminello F
Tunc E
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Turner T
Turner T
Turri G
Turunen A
Tutcu Sahin S
Tutino R
Tutino R
Tutt L
Tuynman J B
Tümer S S
Ucar A
Udayachandran V
Ul-Hasan S
Ulusahin M
Unbehaun K P
Unbehaun K P
Unsworth A
Uslu Ö
Uslu Ö
Uyanik A
Uygur F A
Uysal M
Valente P
Van Rhee C
Van Staden N
Van Straten S
Van Straten S
Van Vuuren S
Vanoni A
Varathan K
Varcada M
Vareda R
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Varghese S
Vaughan-Burleigh S
Vayalapra S
Vaz Pinto G
Vedadi A
Veen O C
Veiga D N
Velez C
Vella I
Vellei S
Ven A H W
Venara A
Vendramin E
Venturelli P
Vergari R
Verma K
Vermeulen D
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Vertaldi S
Vician M
Vieira B N
Vieira B N
Vignali A
Vignaud T
Vigs S
Vijay J
Vijgen G H E J
Vincenti L
Vipond M
Virgilio E
Viscosi F
Vishnu K S
Vita M
Vitali M
Vittori L
Vivian F
Vladova P
Voeten D M
Voort E M F
Vries H S
Vroom Y
Vucicevic A
Vulcano I
Vutipongsatorn K
Vyas V
Wadsworth O J
Waldron D
Walker M
Walsh A
Walsh L
Walsh M
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Warburton T
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Ward K L
Warne M
Warner C
Warner C
Warsame A
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Watson N
Wcislo K
Wei Lim S
Wells A
Wells C I
Welman D
West D
Westerduin E
Westerman T
Weyers J
Wheldon L
White S
Whitehead T
Wickstone C
Wiemann A M
Wijnbergen J W M
Wijnhoven B P L
Wilkerson H T
Wilkes A
Wilkin R
Willemin M
Williams G
Williams L
Williams L
Williams M
Williams R I
Williams R L
Williams S
Williamson E
Wilms H
Wilson C
Wilson T
Wilton S
Wilton S
Windebank J
Winders J
Winstanley J
Withey K
Wong C
Wong C
Wong H L
Wong J
Wong J
Wong J
Wong J
Wong N
Wong R T W
Wood F
Woodburn B
Woodmass M
Woods M
Worsøe J
Wright E
Wright J
Wright O
Wyche A A B
Wynell-Mayow W
Wynter K
Xiao Y
Xuan Tan Z
Yagız Sen A
Yagız Sen A
Yagız Sen A
Yalcinkaya A
Yam S T
Yanikoglu E
Yanishev A
Yanishev A
Yanishev A
Yarenci E
Yasin I H
Yasin I H
Yassaie S
Yassaie S S
Yavas M
Yavuz G
Yeap B
Yelkenci C
Yeni M
Yeo Y Q
Yeoh T
Yesilsancak M
Yi Tew Z
Yi Tew Z
Yildirak M K
Yildirim N
Yildirim R
Yilmaz B S
Yilmaz D
Yilmaz D
Yilmaz I
Yılmaz M
Yilmaz S
Yiu J
Yong S Q
Yoong A
Yotsov T
Young J
Youssef H
Youssef Y
Yu N
Yuksek A
Yumurtaci Ö
Yurdaor S S
Yurdaor S S
Yusuf Z
Yüksek B
Yüksek B
Zaffaroni G
Zaffaroni G
Zaidi A
Zalla T
Zaman S
Zamzow K
Zardab M
Zearmal S
Zeb E
Zeromskas P
Zeynalov F
Zhao J
Zhao S
Zheng S
Zhu L Y
Zoikas A
Zoikas A
Zubowicz M
Zuin M
Zulkefley N
Zuzek R
Žebrák R
Žebrák R
Žebrák R
Publication venue: 'Wiley'
Publication date: 01/01/2019
Field of study

Background: Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery. Methods: A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a centre-specific survey of compliance to enhanced recovery principles. Secondary safety outcomes included anastomotic leak rate and acute kidney injury. Results: A total of 4164 patients were included, with a median age of 68 (i.q.r. 57\u201375) years (54\ub79 per cent men). Some 1153 (27\ub77 per cent) received NSAIDs on postoperative days 1\u20133, of whom 1061 (92\ub70 per cent) received non-selective cyclo-oxygenase inhibitors. After adjustment for baseline differences, the mean time to gastrointestinal recovery did not differ significantly between patients who received NSAIDs and those who did not (4\ub76 versus 4\ub78 days; hazard ratio 1\ub704, 95 per cent c.i. 0\ub796 to 1\ub712; P = 0\ub7360). There were no significant differences in anastomotic leak rate (5\ub74 versus 4\ub76 per cent; P = 0\ub7349) or acute kidney injury (14\ub73 versus 13\ub78 per cent; P = 0\ub7666) between the groups. Significantly fewer patients receiving NSAIDs required strong opioid analgesia (35\ub73 versus 56\ub77 per cent; P < 0\ub7001). Conclusion: NSAIDs did not reduce the time for gastrointestinal recovery after colorectal surgery, but they were safe and associated with reduced postoperative opioid requirement

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Safety of hospital discharge before return of bowel function after elective colorectal surgery

Author: A A Francis
A A Francis
A Abad-Motos
A Abelevich
A Adel
A Agarwal
A Aggiusti
A Ahmed
A Ahmeidat
A Ajmera
A Akisheva
A Al-Azzawi
A Al-Hadithi
A Al-Salihi
A Alagoa João
A Alagoa João
A Alberca-Paramo
A Aldarragi
A Ali
A Ali
A Alonso-Poza
A Alsaif
A Alshakhs
A Amado
A Amico
A Armellini
A Arnold
A Arroyo
A Asif
A Asif
A Atiyah
A Aversano
A B Aksoy
A B Teasdale
A Badran
A Badran
A Barberis
A Bareh
A Barina
A Barkovskaya
A Barrett
A Bartnick
A Bartoli
A Basak
A Batista
A Batterham
A Begaj
A Belli
A Belli
A Benevento
A Bettella
A Bhargava
A Biancafarina
A Biancafarina
A Birindelli
A Birindelli
A Bondurri
A Borakati
A Borakati
A Bordanova Reverter
A Borisova
A Borisova
A Boulbadaoui
A Brescia
A Brodie
A Bugmann
A Burzic
A Busuttil
A C Aru
A C Bilgili
A C Pedersen
A C Quintela
A Caiazzo
A Campbell
A Campbell
A Campbell
A Capozzolo
A Casaril
A Castro
A Centeno
A Chan
A Charalabopoulos
A Charalambous
A Chiang
A Chrimes
A Chuang
A Clavé Llavall
A Clucas
A Coomes
A Couldrey
A Craus-Miguel
A Cruccu
A Cruz
A Cuenca Ramírez
A Cutler
A D Ablett
A D Ablett
A D Antona
A D Cevlik
A Dawson
A Dawson
A De La Llave Serralvo
A de Manzoni Garberini
A de Manzoni Garberini
A de Ruiter
A Debiasio
A Dharni
A Di Cintio
A Dias Matos
A Drane
A Dulskas
A Dworkin
A Díaz Padillo
A E Isik
A Elbayouk
A Emin
A Espí Macías
A F Rocha
A Fares Bucci
A Faustino
A Fernandez
A Fontani
A Forero-Torres
A Forero-Torres
A Forero-Torres
A Foulkes
A Franceschi
A Franceschi
A Fung
A G Marrosu
A G Silva
A Gabarski
A Gadhvi
A Galgano
A Garcea
A Garcia
A García-Vico
A Gavrilina
A Gemini
A Gennai
A Gharooni
A Ghosh
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A Unsworth
A Uyanik
A V Robinson
A Vadillo-Bohorquez
A van der Pool
A Vanoni
A Varghese
A Vedadi
A Venara
A Vignali
A Vucicevic
A W Azhar
A Walsh
A Warsame
A Wells
A Wilkes
A Yagız Sen
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A Yanishev
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A Yebes
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A Zaidi
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Asi Hassane
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C Alves-Vale
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C Belluco
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H Serin
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H T Wilkerson
H Tam
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I Alberdi San Román
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Isf Lau
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J Do
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J Foong
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J Hale
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J Herron
J Herron
J Heyworth
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J Hodson
J Hollingshead
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J Jobson
J Johnston
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J K Luong
J K Luong
J Katunin
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J Knight
J Krupp
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J L Borrow
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J Lee
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J Ly
J M Baião
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J Ng
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J Parnell
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J Perez
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J Pitt
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J Powell
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J R Gomes
J Rachadell
J Rachadell
J Redmond
J Rees
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J Riško
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J Rosales
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J Tan
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Jam Jardim
Jaw Mogg
Jmsn Jayalath
Jph Tam
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Jwm van Wijnbergen
Jzj Chiu
K Ahmed
K Akbari
K Akbari
K Beckers
K Busby
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K Chapple
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K D Lycke
K D Lycke
K Das
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K Kunčarová
K Kwok
K L Ward
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K M Konstantinidis
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Kgh van de Pas
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L Adeusi
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L M Esposito
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L M Piotet
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L Nelson
L Ong
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L P Delaugere
L Pellegrino
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L R Manley
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L Riba
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L T Davis
L T Lai
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L Te Molder
L Theocharidou
L Tincknell
L Titu
L Tong
L Tutt
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L Wheldon
L Williams
L Williams
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Lps Stassen
Lyc Tam
M A Bin Amran
M A Mens
M Aba
M Adra
M Ahmed
M Ahmed
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M Al-Ausi
M Alasmar
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M Allen
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M Boland
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M Bosch Ramírez
M Bradbury
M Brkljac
M Buari
M Bugelli
M Bujda
M C Giuffrida
M C Gordinou de Gouberville
M C Haksal
M C Martin
M C Seker
M Calgaro
M Calussi
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M Caratão
M Cavallini
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M Ceresoli
M Chadwick
M Charalambides
M Charalambos
M Chauhan
M Chowdhary
M Chu
M Chu
M Cigognini
M Claro
M Claro
M Compton
M Costa
M Costa
M Couto
M Coyle
M Creciun
M Cunha
M Curran
M Curran
M D Kjaer
M D Kjaer
M D Kocer
M D Ângelo
M Danzi
M De Angelis
M De Jesus
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M De Prizio
M De Rosa
M De Rosa
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M Dixon
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M Duarte
M Duarte
M Dubovský
M E Billo
M E Cufari
M E Ossola
M E Stellingwerf
M Eizaguirre Ubegun
M Elghobashy
M Enevoldsen
M Erdem
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M Estaire Gomez
M Evans
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M F Bath
M F Bitonti
M F Cunha
M F Gerhards
M F Çetin
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M Farkašová
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M Ferreira
M Ferreira
M Ferreira
M Flores
M Fragoso
M Franco
M Frasson
M Frattalone
M G Calzada
M G Muthukumar
M Gabriel
M Gallagher
M Garcia
M Garcia
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M Gerdsen
M Ghaly
M Giglio
M Gilani
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M Goble
M Gough
M Gout
M Gout
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M Grassia
M Gray
M Guerrieri
M Guler
M Guruswamy
M H Agca
M H Aly
M Hansmann
M Hanušová
M Hardie Boys
M Harris
M Harron
M Hill
M Holmes
M Hoo
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M Hughes
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M Hussain
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M I Orue-Echebarria
M Ibañez Alda
M Illahi
M Imperatore
M Imtiaz
M Inama
M Isse
M J Gómez Jurado
M J Jervis
M J Machatschek
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M J Sánchez
M Jakubauskas
M Jakubauskas
M Jamal
M Johnson
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M Jung
M K Aktas
M K Aktas
M K Aktas
M K Yildirak
M Kara
M Karamanliev
M Karamanliev
M Kaya
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M Khalil
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M Kiandee
M Kip
M Ko
M Konstantinidis
M Konstantinidis
M Kovacevic
M Kowal
M Kowal
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M Kybransiene
M L Aguilera
M L Aguilera
M L Aguilera
M L Garcia Jimenez
M L Haller
M L Murru
M L Serra
M L Serra
M Lamas
M Latter
M Leaning
M Leite
M Losada
M Ludvik
M Lázaro Cardona
M López Otero
M López Otero
M M Aguilar-Martínez
M M Soriano Liébana
M Maciaszek
M Magnoli
M Magnoli
M Malerba
M Manigrasso
M Manigrasso
M Mansoor
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M Marco
M Martins
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M Marx
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M McTiernan
M Mendes
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M Merayo Álvarez
M Merichal
M Millán-Scheiding
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M Miscampbell
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M Molina-Florez
M Monks
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M Morales
M Moreira
M Morgado
M Morino
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M N Armitage
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M O Sauvain
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M Owen
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M P Gosselink
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M Panikkar
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M Papandrea
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M Peyroteo
M Pirillo
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M Podda
M Podda
M Poelman
M Pospíšil
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M Poustie
M Povey
M Prem
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M Pös
M R Almeida
M R Almeida
M R Jones
M Rahi
M Rainey
M Ransome
M Raos
M Reia
M Resendes
M Riccardi
M Ricciardiello
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M Romano
M Romano
M Romelli
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M Ronconi
M Rosete
M Rosete
M Rufas
M S Erturk
M S Milani
M S Tulek
M Salibasic
M Salman
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M Sammut
M Santangelo
M Santos
M Santos
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M Saunders
M Schachtel
M Scricciolo
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M Silva
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M Swamad
M Tabibi
M Taylor
M Thornton
M Tomé
M Trippetti
M Trompetto
M Trompetto
M Truant
M Ulusahin
M Uribe Isado
M Uysal
M V Fernandez Illera
M Varcada
M Veras Lista
M Verdaguer Tremolosa
M Vician
M Vipond
M Vita
M Vitali
M W Ruggiu
M W Tissink
M Walker
M Walsh
M Warne
M Willemin
M Williams
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M Woods
M Y Hassan Serry
M Yavas
M Yeni
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M Yılmaz
M Zardab
M Zubowicz
M Zuin
M Á Sánchez-Gálvez
M Ölmez
M Özbek
Maj Becker
Mja McMillan
Mmh Farhan-Alanie
Mmh Farhan-Alanie
Mpcm Smit
Mpe Ng
Mtf Jense
Mwa van Tilburg
Mwj Stommel
N Abdulrahman
N Arkadopoulos
N Aykun
N Bansal
N Ben Khaled
N Bull
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N Chetta
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N D Machado
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N Dabab
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N Falco
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N G
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N Oliveira
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N Yu
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Nda Blefari
Nmro Lopes
Nrf Sluijpers
O Adeleye
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O Biyiklioglu
O Blackwood
O C Mana
O C Veen
O Cheng
O Claramonte Bellmunt
O Claramonte Bellmunt
O Costigan
O Delisau Puig
O Dixon
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O F Kuyumcu
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Saa Dossa
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T Antonova
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T Arthur
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T C Santos
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T Netke
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T Powell
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T R van Elst
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T Scurr
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T Zalla
Tbw Soh
Tsm Chu
Tys Leow
U Akbani
U Anthony-Uzoeto
U Cengiz
U D'Errico
U de Andres Olabarria
U de Andres Olabarria
U Janković
U Memis
U Muhammad
U Pahalawatta
U S Loeve
U Önsal
V Adamo
V Albert
V Andriola
V C Isler
V Capella
V Dimitrov
V Eismontas
V Erten
V Farina
V Fernandes
V Fico
V Ford
V Francisco
V Gopalan
V Graziadei
V Horta
V Ivanov
V Ivanov
V Jotautas
V Jozaf
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V Kilic
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V La Manna
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V M Ćuk
V Marchionini
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V Misra
V Murray
V Murray
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V Nevoso
V Neykov
V Neykov
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V Ozben
V P Geneta
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V Pedro
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V Ripetti
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V Schaeff
V Taranu
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V Testa
V Thakrar
V Thirugnanasundralingam
V Tonini
V Udayachandran
V V Ćuk
V V Ćuk
V Vigorita
V Vyas
W A Bemelman
W Beedham
W Clay
W Fleischl
W Fordyce
W Fradley
W J English
W J Owen
W K Lau
W Lam
W Mculu
W Perchard
W Pyc
W Pyc
W Reynolds
W S Ngu
W Saleh
W Simpson
W Sloper
W Sloper
W Thomson
W Wynell-Mayow
Wur Ahmed
X Sousa
Y Ali
Y Bei
Y Bekker
Y Bhahirathan
Y Bhahirathan
Y Bharwada
Y Chechelnitskaya
Y D Lee
Y Demiroglu
Y E Alim
Y E Aytin
Y E Karapinar
Y El Kasmy El Kasmi
Y El Kasmy El Kasmi
Y El Kasmy El Kasmi
Y Embury-Young
Y Gercek
Y J Alame
Y J Lee
Y J Soh
Y K Goh
Y K Lim
Y Karaman
Y Kaya
Y Kaya
Y L Pang
Y L Wang
Y Li
Y M Tissen
Y Mahmoudi
Y Majeed
Y Mitkov
Y N Goh
Y Nikookam
Y Q Yeo
Y Qamar
Y Shafiq
Y Toyi
Y Vroom
Y Xiao
Y Youssef
Y Z Beh
Yiz Acherman
Z Abdulrahman
Z Akbar
Z Al-Saraff
Z Al-Sarraf
Z Ali
Z B Koçak
Z Ballarini
Z Carrington
Z Garoufalia
Z Goolam-Mahomed
Z H Sam
Z Habib
Z Iqbal
Z Millar
Z Ngwenya
Z Noriega
Z S Demirci
Z Sheikh
Z Xuan Tan
Z Y Boh
Z Yi Tew
Z Yi Tew
Z Yusuf
Á Navarro Barrios
Çagri Girit
É Dockry
Ö Kürklü
Ö Uslu
Ö Uslu
Ö Yumurtaci
Publication venue: 'Wiley'
Publication date: 01/01/2020
Field of study

Background: Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.Methods: A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien-Dindo classification system.Results: A total of 3288 patients were included in the analysis, of whom 301 (9.2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4-7) and 7 (6-8) days respectively (P < 0.001). There were no significant differences in rates of readmission between these groups (6.6 versus 8.0 per cent; P = 0.499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0.90, 95 per cent c.i. 0.55 to 1.46; P = 0.659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34.7 versus 39.5 per cent; major 3.3 versus 3.4 per cent; P = 0.110).Conclusion: Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients

Archivio istituzionale della Ricerca - Università degli Studi di Parma

Catalogo dei prodotti della ricerca

Archivio della ricerca- Università di Roma La Sapienza

Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli"

Safety of hospital discharge before return of bowel function after elective colorectal surgery

Author: A A Francis
A A Francis
A A W van Geloven
A Abad-Motos
A Abelevich
A Adel
A Agarwal
A Aggiusti
A Ahmed
A Ahmeidat
A Ajmera
A Akisheva
A Al-Azzawi
A Al-hadithi
A Al-Salihi
A Alagoa João
A Alagoa João
A Alberca-Paramo
A Aldarragi
A Ali
A Ali
A Alonso-Poza
A Alsaif
A Alshakhs
A Amado
A Amico
A Armellini
A Arnold
A Arroyo
A Asif
A Asif
A Atiyah
A Aversano
A B Aksoy
A Badran
A Badran
A Barberis
A Bareh
A Barina
A Barkovskaya
A Barrett
A Bartnick
A Bartoli
A Basak
A Batista
A Batterham
A Begaj
A Belli
A Belli
A Benevento
A Bettella
A Bhargava
A Biancafarina
A Biancafarina
A Birindelli
A Birindelli
A Bondurri
A Borakati
A Borakati
A Bordanova Reverter
A Borisova
A Borisova
A Boulbadaoui
A Brescia
A Brodie
A Bugmann
A Burzic
A Busuttil
A C Aru
A C Bilgili
A C Pedersen
A C Quintela
A Caiazzo
A Campbell
A Campbell
A Campbell
A Capozzolo
A Casaril
A Centeno
A Chan
A Charalabopoulos
A Charalambous
A Chiang
A Chrimes
A Chuang
A Clavé Llavall
A Coomes
A Couldrey
A Craus-Miguel
A Cruccu
A Cruz
A Cuenca Ramírez
A D Ablett
A D Ablett
A D Antona
A D Cevlik
A Dawson
A Dawson
A De La Llave Serralvo
A de Manzoni Garberini
A de Manzoni Garberini
A Debiasio
A Dharni
A Di Cintio
A Dias Matos
A Drane
A Dulskas
A Dworkin
A Díaz Padillo
A E Isik
A Elbayouk
A Emin
A Espí Macías
A F Rocha
A Fares Bucci
A Faustino
A Fernandez
A Fontani
A Forero-Torres
A Forero-Torres
A Forero-Torres
A Franceschi
A Franceschi
A Fung
A G Marrosu
A G Silva
A Gabarski
A Gadhvi
A Galgano
A Garcea
A Garcia
A Gavrilina
A Gemini
A Gennai
A Gharooni
A Ghosh
A Giani
A Giannella
A Gibbins
A Gil
A Gil-Catalán
A Gilliam
A Giri
A Goede
A Gopaul
A Gordon
A Gori
A Grüter
A Guerreiro
A Guglielmi
A Guner
A Gómez del Pulgar
A Güldag
A H Adam
A H Dyer
A H W van de Ven
A Haji
A Henkens
A Herd
A Heybourne
A Hickman
A Hogan
A Hogan
A Hotchkies
A Huot
A Hylands
A I Pinillos
A Ioannidis
A Ioannidis
A Ipor
A Isabello
A Isik
A Izquierdo Moreno
A Izzarina
A Jackson
A Jacobson
A Jain
A James
A Jones
A Joseph
A Jovaisaite
A Kanitkar
A Karabulut
A Kechagias
A Kechagias
A Kechagias
A Kefleyesus
A Kelliher
A Khan
A Khanan Kaabneh
A Kilinç
A Kisiel
A Kisiel
A Kler
A Kopp
A Kumar
A Kurt
A Kushairi
A L Mihaljevic
A Landaluce Olavarria
A Laranjeira
A Larcinese
A Lauretta
A Lauretta
A Litvin
A Litvin
A Loizidou
A Longheu
A Longshaw
A Lucchi
A Lucchi
A M Brandsma
A M Cinza
A M Correia
A M Estévez Diz
A M Seckler
A M Wiemann
A Machado
A Madhavan
A Maffioli
A Magri Piccinini
A Mahmoud
A Mandal
A Manso
A Marano
A Marcos Rodrigo
A Margarida
A Mark-Christensen
A Mark-Christensen
A Maroli
A Martensen
A Martinez
A Mathioulaki
A McTighe
A Mereu
A Midgen
A Millward
A Mondal
A Mondal
A Moosa
A Mora
A Morris
A Mukkavilli
A Nair
A Navío
A Nayeem
A Neilson
A Newton
A Nicolaides
A O Sunay
A O'Neill
A Ojakããr
A Ong
A Otto
A Otto
A Ozolins
A P Torre
A Pacheco
A Paclík
A Palkhi
A Palmer
A Pandya
A Panyko
A Paolucci
A Parisi
A Paspala
A Percassi
A Percivale
A Pergel
A Pesce
A Picciariello
A Picciariello
A Pietrabissa
A Pimentel
A Piperidis
A Poncelet
A Portugal Martínez
A Powell-Chandler
A Powell-Chandler
A Prodromidou
A Pullybank
A Pérez Ortega
A R Loureiro
A R Martins
A R Pentony
A Ragavoodoo
A Ragavoodoo
A Rahman
A Rais
A Ramdin
A Ramjeeawon
A Ramwell
A Rankin
A Rashid
A Realis Luc
A Reddy
A Refalo
A Rencuzogullari
A Ribeiro
A Rodríguez Sánchez
A Roggiani
A Ruparelia
A Ruzzenente
A Rylance
A S Ferreira
A S H M van Dalen
A S H M van Dalen
A Saba
A Sagnotta
A Sagnotta
A Sagredo Cuartango
A Saha
A Saiyed
A Saiyed
A Samee
A Sangheli
A Savchenko
A Saxena
A Schimera
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A Sgrò A Simioni
A Sgrò A Simioni
A Sgrò A Soares
A Sgrò F Argenti
A Shashidhara
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A Simioni
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A Sivinš
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A Slepavicius
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A Spaziani
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A Sunal
A Sánchez López
A Tamosiunas
A Tang
A Tınaz
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A Trap
A Trujillo Barbadillo
A Truškovs
A Tura
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A Ucar
A Unsworth
A Uyanik
A V Robinson
A van der Pool
A Vanoni
A Varghese
A Vedadi
A Venara
A Vignali
A Vucicevic
A Walsh
A Warsame
A Wells
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A Yagız Sen
A Yagız Sen
A Yagız Sen
A Yalcinkaya
A Yanishev
A Yanishev
A Yanishev
A Yebes
A Yebes
A Yoong
A Yuksek
A Z Sahin
A Zaidi
A Zoikas
A Zoikas
B Akram
B Aksoy
B Allen
B B Ozkan
B B Ozmen
B Baljer
B Baykan
B Berry
B Blaser
B Blaser
B Boev
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B Braccio
B Buckland
B Campbell
B Campillo Alonso
B Can
B Carhart
B Castro
B Chandrasekar
B Chrisp
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B Cismasiu
B Cresswell
B D Brandao
B Demirtas
B Desmond
B Dias
B Dieguez
B Djeugam
B E Baki
B Ekci
B Fakim
B Fanibi
B Frezza
B Gagliardi
B Gagliardi
B Gurung
B Güner
B Ibrahim
B J Finch
B J Finch
B Jenkins
B Karip
B Kulendrarajah
B Kutlu
B L van Leeuwen
B Langenhoff
B Liu
B Mekaeil
B Mikhail
B Molteni
B Molteni
B Mutlu
B N Jepsen
B N Vieira
B N Vieira
B Nasimi
B Ng
B P L Wijnhoven
B Pando
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M Morales
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N E Samalavicius
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null Almeida
null ItSURG
null null
O Adeleye
O Alhalabi
O Aliosin
O Anabitarte Bautista
O Anabitarte Bautista
O Anabitarte Bautista
O Anabitarte Bautista
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O Awokoya
O Bauermeister Potts
O Biyiklioglu
O Blackwood
O C Mana
O C Veen
O Cheng
O Claramonte Bellmunt
O Claramonte Bellmunt
O Costigan
O Dixon
O Esteban Sinovas
O Fafemi
O Flannery
O Ghazouani
O Hall
O Holman
O Houdek
O J Wadsworth
O Jones
O Kirnon-Jackman
O Komolafe
O Kopac
O Malý
O McAuliffe
O McGregor
O Milliet
O Morice
O O Onafowokan
O Ojofeitimi
O Oke
O Page
O Pittet
O Rotimi
O Skan
O Sotona
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O Wright
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P A Kasar
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Q Lin
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R A Schasfoort
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R Bate
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S A A Dossa
S A Dingemans
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S A Pherwani
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S Altiner
S Amicucci
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S Aresu
S Aresu
S Ayyar
S B Erichsen
S B Rassool
S Badhrinarayanan
S Basso
S Beqiri
S Berec
S Berti
S Bhatia
S Bhopal
S Bianchini
S Bini
S Bishop
S Bodur
S Bofarid
S Brandsborg
S Brandsborg
S Brooks
S Brown
S Brown
S Browne
S Butt
S C S Simon
S C Sautter
S Campanella
S Campbell
S Cantafio
S Carlos
S Carlton-Carew
S Casiraghi
S Catarino
S Catarino
S Cerasari
S Chatterjee-Woolman
S Childs
S Chodora
S Christie
S Christy
S Colombo
S Costa
S Cravano
S D Ahsan
S Dansuk
S Dass
S Davison
S Debono
S Delibegovic
S Delibegovic
S Delibegovic
S Delibegovic
S Denley
S Deol
S Dimitriadis
S Dindyal
S Dixon
S Durdevic
S Eames
S Edwards
S Eftychiou
S Epton
S F H ten Doesschate
S F H ten Doesschate
S F Martins
S Famularo
S Farik
S Fenn
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S Figueroa Jiménez
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S I B Adams
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S J Chapman
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S J Moug
S J P McLaughlin
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S Jasionowska
S Jeong
S Jerí-McFarlane
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S Lawday
S Lee
S Lennock
S Leventoglu
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S Lockwood
S M C J Coulter-Nile
S M F Abdulrahman
S M Khan
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T A Johnson
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T C Santos
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T C Shortland
T C Sá F M Bernardes
T C van Smaalen
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T Cuming
T Fadipe
T Garofalidou
T Golda
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T H Mihailidis
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T Hosfield
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T Jaffer
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T Louro
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T Melaugh
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T Moinhos
T Moore
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T Netke
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T Oyebola
T Pascual Vicente
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T Powell
T Poškus
T Queiros
T R van Elst
T Raymond
T Richards
T Ross
T S Hany
T S M Chu
T Sammour
T Sariçiçek
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T Seiboldt
T Skalický
T Slimbajevs
T Tanvir
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T Turner
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T van Elst
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T Warburton
T Westerman
T Whitehead
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T Y S Leow
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U Akbani
U Anthony-Uzoeto
U Cengiz
U D'Errico
U de Andres Olabarria
U de Andres Olabarria
U Janković
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U S Loeve
U Önsal
V Adamo
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V Andriola
V C Isler
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V Dimitrov
V Eismontas
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V Francisco
V Gopalan
V Graziadei
V Horta
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V Jozaf
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W Pyc
W Reynolds
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W Sloper
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W Thomson
W U R Ahmed
X Sousa
Y Ali
Y Bhahirathan
Y Bhahirathan
Y Bharwada
Y Chechelnitskaya
Y D Lee
Y Demiroglu
Y E Alim
Y E Aytin
Y E Karapinar
Y El Kasmy El Kasmi
Y El Kasmy El Kasmi
Y El Kasmy El Kasmi
Y Embury-Young
Y Gercek
Y I Z Acherman
Y J Alame
Y J Lee
Y J Soh
Y K Lim
Y Karaman
Y Kaya
Y Kaya
Y L Pang
Y L Wang
Y Li
Y M Tissen
Y Mahmoudi
Y Majeed
Y Mitkov
Y N Goh
Y Nikookam
Y Q Yeo
Y Shafiq
Y Toyi
Y Vroom
Y Xiao
Y Youssef
Z Abdulrahman
Z Akbar
Z Al-Saraff
Z Al-Sarraf
Z Ali
Z B Koçak
Z Ballarini
Z Carrington
Z Garoufalia
Z Goolam-Mahomed
Z H Sam
Z Habib
Z Iqbal
Z Millar
Z Ngwenya
Z Noriega
Z S Demirci
Z Sheikh
Z Xuan Tan
Z Y Boh
Z Yi Tew
Z Yi Tew
Z Yusuf
Çagri Girit
Ö Kürklü
Ö Uslu
Ö Uslu
Ö Yumurtaci
Publication venue: Oxford University Press (OUP)
Publication date: 24/01/2020
Field of study

Abstract Background Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function. Methods A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien–Dindo classification system. Results A total of 3288 patients were included in the analysis, of whom 301 (9·2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4–7) and 7 (6–8) days respectively (P &lt; 0·001). There were no significant differences in rates of readmission between these groups (6·6 versus 8·0 per cent; P = 0·499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0·90, 95 per cent c.i. 0·55 to 1·46; P = 0·659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34·7 versus 39·5 per cent; major 3·3 versus 3·4 per cent; P = 0·110). Conclusion Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients. </jats:sec

Crossref

Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

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Abelevich A
Ablett A D
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Adam A H
Adamo V
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Adiyaman C
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Agarwal A
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Agca M H
Aggiusti A
Agresta F
Aguilera M L
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Ahmad H
Ahmed A
Ahmed H
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Ahmed M
Ahmed M
Ahmed S
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Ahmed W U R
Ahmeidat A
Ahsan S D
Ainsworth P
Aitken E
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al-Ausi M
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null null
null null
null null
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Paixão I
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Pilotta F
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Pintabona G
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Pipitone Federico N S
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Piras K
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Poustie M
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Powell-Chandler A
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Realis Luc A
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Rencuzogullari A
Resendes M
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Reveendran D
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Roche C D
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Rshaidat H
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Ruggiu G V
Ruggiu M W
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Ruparelia A
Ruppeldt P
Russell C
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Ruzzenente A
Rye D S
Rylance A
Saba A
Sabanci R
Sabir K
Sabnani R
Sagnotta A
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Saha A
Sahin A Z
Sahin C
Sait S
Sait S
Saiyed A
Saiyed A
Salamone G
Salaris C
Saleh R
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Salman M
Saluja T
Salvadori R
Sam Z H
Samake M
Samalavicius N E
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Sammarco G
Sammour T
Sammut K
Sammut M
Sampietro G
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Sangheli A
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Santos T C
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Sapre D
Saraiva P
Saraiva R
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Sariçiçek T
Sarıgül L
Sartaj F
Sasia D
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Satilmisoglu M
Sauka J
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Sautter S C
Sauvain M O
Savchenko A
Savino G
Savino G
Saxena A
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Schaeff V
Schaeff V
Schaeff V
Schasfoort R A
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Schiavone D
Schimera A
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Scurr T
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Seite E
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Sel E K
Sellahewa C
Selvaggi F
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Selvaraj T
Semiz A
Senaratne R
Senhorinho R
Senyigit E
Sequeira Campos M
Serin H
Serin H
Serra D
Serra M L
Serra M L
Sewart E
Sgrò A
Sgrò A
Sgrò A
Sgrò A
Shaban F
Shafiq Y
Shah D R
Shah N
Shah S M
Sharkey S
Sharma P
Sharma S
Sharriff H
Shashidhara A
Sheikh Z
Sheldon J
Shirazi B
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Shortland T C
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Shortland T C
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Shrestha S
Siaw Yen Lai R
Silva A
Silva A
Silva A G
Silva F
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Simcikas D
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Sinha S
Sinibaldi G
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Sisley M
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Sivinš A
Skalický A
Skalický P
Skalický T
Skan O
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Skejø C D
Skipworth C
Skull A
Slepavicius A
Slimbajevs T
Sliwinski S
Slooter G
Sloper W
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Sluijpers N R F
Smaalen T C
Smart N J
Smillie R
Smit M P C M
Smith B
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Smith E
Smith F M
Smolarek S
Soare C
Soares A
Soares A
Soares A
Soares B
Soares D
Sobotková K
Soh T B W
Soh Y J
Solomou G
Soma A
Soman S
Sookramanien S R
Sotona O
Sousa D
Sousa M
Sousa X
Southgate A
Söyleyici B
Sparke A
Sparta C
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Spazzapan M
Speake D
Spinelli A
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Spirito C
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Spyrou I
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Stainer B
Stanfield B
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Stephens I
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Stewart P
Stijns R C H
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Strupas K
Stubbs B
Stylianides N
Subramanian I
Sucameli F
Sucháň P K
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Suchett-Kay I
Suchett-Kaye I
Sunal A
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Sysum K
Sørensen J S
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Tabibi M
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Talamo G
Talamo G
Taleongpong P
Tam H
Tam J P H
Tam J P H
Tam L Y C
Tamini N
Tamini N
Tammaro N
Tamosiunas A
Tan H L
Tan I X H
Tan J
Tan J
Tan K
Tan Q J
Tan R
Tan R R
Tan T K
Tandon R
Taneja S
Tang A
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Taranu V
Tasdelen I
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Testa V
Testa V
Tewhaiti-Smith J
Thakkar R
Thakral N
Thakrar C
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Thakrar V
Thavayogan R
Thavayogan R
Thäwel T
Theocharidou L
Theodoraki G
Theodoropoulou K
Thirugnanasundralingam V
Thomas D A
Thomas G
Thomas P
Thomas S
Thompson B
Thompson C
Thompson E
Thomson W
Thorn C
Thornton M
Tie-Gill T
Tiftik E
Tiftik E
Tilburg M W A
Tilocca P L
Tilocca P L
Timms S
Tınaz A
Tincknell L
Tipi O U
Tirelli F
Tirelli F
Tirotta F
Tissen Y M
Tissink M W
Titu L
Tjoakarfa J
To N
Toh C
Toh C
Toklu R
Tomanová D
Tomas K
Tombul H B
Tomé M
Tonchev P
Toner S
Tong L
Tonini V
Topchubaev D
Toprak S
Torrance A
Torre A P
Torselli D
Toyi Y
Tran N
Trap A
Trastulli S
Treskoň R
Tribedi T
Tringali D
Trippetti M
Tromp J
Trompetto M
Trompetto M
Trotter J
Truant M
Trussell S
Truškovs A
Tulek M S
Tuminello F
Tunc E
Tung J
Tupper P
Tura A
Turk E G
Turner C
Turner T
Turner T
Turri G
Turunen A
Tutcu Sahin S
Tutino R
Tutino R
Tutt L
Tuynman J B
Tümer S S
Ucar A
Udayachandran V
Ul-Hasan S
Ulusahin M
Unbehaun K P
Unbehaun K P
Unsworth A
Uslu Ö
Uslu Ö
Uyanik A
Uygur F A
Uysal M
Valente P
Van Rhee C
Van Staden N
Van Straten S
Van Straten S
Van Vuuren S
Vanoni A
Varathan K
Varcada M
Vareda R
Varghese A
Varghese S
Vaughan-Burleigh S
Vayalapra S
Vaz Pinto G
Vedadi A
Veen O C
Veiga D N
Velez C
Vella I
Vellei S
Ven A H W
Venara A
Vendramin E
Venturelli P
Vergari R
Verma K
Vermeulen D
Vernon D
Vertaldi S
Vician M
Vieira B N
Vieira B N
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Vishnu K S
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Vroom Y
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Vulcano I
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Warner C
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Wright O
Wyche A A B
Wynell-Mayow W
Wynter K
Xiao Y
Xuan Tan Z
Yagız Sen A
Yagız Sen A
Yagız Sen A
Yalcinkaya A
Yam S T
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Yanishev A
Yanishev A
Yanishev A
Yarenci E
Yasin I H
Yasin I H
Yassaie S
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Yavuz G
Yeap B
Yelkenci C
Yeni M
Yeo Y Q
Yeoh T
Yesilsancak M
Yi Tew Z
Yi Tew Z
Yildirak M K
Yildirim N
Yildirim R
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Yilmaz D
Yilmaz D
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Youssef H
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Yumurtaci Ö
Yurdaor S S
Yurdaor S S
Yusuf Z
Yüksek B
Yüksek B
Zaffaroni G
Zaffaroni G
Zaidi A
Zalla T
Zaman S
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Zardab M
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Zeb E
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Zhao J
Zhao S
Zheng S
Zhu L Y
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Zoikas A
Zubowicz M
Zuin M
Zulkefley N
Zuzek R
Žebrák R
Žebrák R
Žebrák R
Publication venue
Publication date: 01/01/2019
Field of study

Background Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery. Methods A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a centre-specific survey of compliance to enhanced recovery principles. Secondary safety outcomes included anastomotic leak rate and acute kidney injury. Results A total of 4164 patients were included, with a median age of 68 (i.q.r. 57-75) years (54 center dot 9 per cent men). Some 1153 (27 center dot 7 per cent) received NSAIDs on postoperative days 1-3, of whom 1061 (92 center dot 0 per cent) received non-selective cyclo-oxygenase inhibitors. After adjustment for baseline differences, the mean time to gastrointestinal recovery did not differ significantly between patients who received NSAIDs and those who did not (4 center dot 6 versus 4 center dot 8 days; hazard ratio 1 center dot 04, 95 per cent c.i. 0 center dot 96 to 1 center dot 12; P = 0 center dot 360). There were no significant differences in anastomotic leak rate (5 center dot 4 versus 4 center dot 6 per cent; P = 0 center dot 349) or acute kidney injury (14 center dot 3 versus 13 center dot 8 per cent; P = 0 center dot 666) between the groups. Significantly fewer patients receiving NSAIDs required strong opioid analgesia (35 center dot 3 versus 56 center dot 7 per cent; P < 0 center dot 001). Conclusion NSAIDs did not reduce the time for gastrointestinal recovery after colorectal surgery, but they were safe and associated with reduced postoperative opioid requirement

Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli"

Validation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery

Author: A. A. B. Wyche
A. A. Francis
A. A. Francis
A. Aamir
A. Abad-Motos
A. Adel
A. Adeogun
A. Adlan
A. Agarwal
A. Aggiusti
A. Ahmad
A. Ahmed
A. Ahmeidat
A. Ajmera
A. Akhtar
A. Akisheva
A. Al-Azzawi
A. Al-hadithi
A. Al-Mousawi
A. Al-Salihi
A. Alagappan
A. Alagoa João
A. Alagoa João
A. Alberca-Paramo
A. Aldarragi
A. Ali
A. Ali
A. Ali
A. Ali
A. Alonso-Poza
A. Alsaif
A. Alshakhs
A. Alwandi
A. Amado
A. Amico
A. Amoah-Arko
A. Ang
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E. 't Hart
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W. Ye
X. Sousa
X. Wang
Y. Ali
Y. Bei
Y. Bekker
Y. Bhahirathan
Y. Bhahirathan
Y. Bharwada
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Y. Chechelnitskaya
Y. Chen
Y. Choudhary
Y. D. Lee
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Y. Dennis
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Y. El Kasmy El Kasmi
Y. El Kasmy El Kasmi
Y. El Kasmy El Kasmi
Y. Embury-Young
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Y. Mahmoudi
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Y. N. Goh
Y. N. Neo
Y. Nikookam
Y. Patrick
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Y. Premakumar
Y. Q. Yeo
Y. Qamar
Y. R. Chin
Y. S. Dupaguntla
Y. Shafiq
Y. Toyi
Y. Varathan
Y. Vroom
Y. W. Smart
Y. Xiao
Y. Xu
Y. Y. He
Y. Youssef
Y. Z. Beh
Y. Zhang
Y. Zhu
Z. A. R. Jawad
Z. Abdulrahman
Z. Afzal
Z. Akbar
Z. Al-Saraff
Z. Al-Sarraf
Z. Ali
Z. B. Koçak
Z. Ballarini
Z. Cargill
Z. Carrington
Z. Cheng Lim
Z. China
Z. D. Yin
Z. Garoufalia
Z. Goolam-Mahomed
Z. H. Lim
Z. H. Sam
Z. Habib
Z. Iqbal
Z. Kazmi
Z. Mesbah
Z. Millar
Z. Mughal
Z. Ngwenya
Z. Noriega
Z. Philip
Z. S. Demirci
Z. Sattar
Z. Sheikh
Z. Sheikh
Z. Soonawalla
Z. Taylor
Z. Xuan Tan
Z. Y. Boh
Z. Yi Tew
Z. Yi Tew
Z. Yusuf
Á. Navarro Barrios
Ç. a. g. r. i. Girit
É. Dockry
Ö. Kürklü
Ö. Uslu
Ö. Uslu
Ö. Yumurtaci
Publication venue: Oxford University Press (OUP)
Publication date: 06/01/2022
Field of study

Abstract Background Postoperative acute kidney injury (AKI) is a common complication of major gastrointestinal surgery with an impact on short- and long-term survival. No validated system for risk stratification exists for this patient group. This study aimed to validate externally a prognostic model for AKI after major gastrointestinal surgery in two multicentre cohort studies. Methods The Outcomes After Kidney injury in Surgery (OAKS) prognostic model was developed to predict risk of AKI in the 7 days after surgery using six routine datapoints (age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker). Validation was performed within two independent cohorts: a prospective multicentre, international study (‘IMAGINE’) of patients undergoing elective colorectal surgery (2018); and a retrospective regional cohort study (‘Tayside’) in major abdominal surgery (2011–2015). Multivariable logistic regression was used to predict risk of AKI, with multiple imputation used to account for data missing at random. Prognostic accuracy was assessed for patients at high risk (greater than 20 per cent) of postoperative AKI. Results In the validation cohorts, 12.9 per cent of patients (661 of 5106) in IMAGINE and 14.7 per cent (106 of 719 patients) in Tayside developed 7-day postoperative AKI. Using the OAKS model, 558 patients (9.6 per cent) were classified as high risk. Less than 10 per cent of patients classified as low-risk developed AKI in either cohort (negative predictive value greater than 0.9). Upon external validation, the OAKS model retained an area under the receiver operating characteristic (AUC) curve of range 0.655–0.681 (Tayside 95 per cent c.i. 0.596 to 0.714; IMAGINE 95 per cent c.i. 0.659 to 0.703), sensitivity values range 0.323–0.352 (IMAGINE 95 per cent c.i. 0.281 to 0.368; Tayside 95 per cent c.i. 0.253 to 0.461), and specificity range 0.881–0.890 (Tayside 95 per cent c.i. 0.853 to 0.905; IMAGINE 95 per cent c.i. 0.881 to 0.899). Conclusion The OAKS prognostic model can identify patients who are not at high risk of postoperative AKI after gastrointestinal surgery with high specificity. Presented to Association of Surgeons in Training (ASiT) International Conference 2018 (Edinburgh, UK), European Society of Coloproctology (ESCP) International Conference 2018 (Nice, France), SARS (Society of Academic and Research Surgery) 2020 (Virtual, UK). </jats:sec

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