Variational calculations for resonance oscillations of inhomogeneous plasmas

The electrostatic resonance properties of an inhomogeneous plasma column are reported by application of the Rayleigh-Ritz method. A description of the rf equation of motion and pressure term that expresses the system of equations in Euler-Lagrange form is presented. The Rayleigh-Ritz procedure is applied to the corresponding Lagrangian to obtain approximate resonance frequencies and eigenfunctions. An appropriate set of trial coordinate functions is defined, which leads to frequency and eigenfunction estimates

Multifrequency Observations of One of the Largest Supernova Remnants in the Local Group of Galaxies, LMC - SNR J0450-709

We present the results of new Australia Telescope Compact Array (ATCA) observations of one of the largest supernova remnants, SNR J0450-709, in the Local Group of galaxies. We found that this Large Magellanic Cloud (LMC) ob ject exhibits a typical morphology of an old supernova remnant (SNR) with diameter D=102x75+-1 pc and radio spectral index alpha=-0.43+-0.06. Regions of high polarisation were detected with peak value of ~40%.Comment: 7 pages, 4 figures, accepted for publication in Serbian Astronomical Journa

Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal.

Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the Golgi. Norwalk virus nonstructural protein p22 contains a YXΦESDG motif that mimics a di-acidic ER export signal in both sequence and function. However, unlike normal ER export signals, the ER export signal mimic of p22 is necessary for apparent inhibition of normal COPII vesicle trafficking, which leads to Golgi disassembly and antagonism of Golgi-dependent cellular protein secretion. This is the first reported function for p22. Disassembly of the Golgi apparatus was also observed in cells replicating Norwalk virus, which may contribute to pathogenesis by interfering with cellular processes that are dependent on an intact secretory pathway. These results indicate that the ER export signal mimic is critical to the antagonistic function of p22, shown herein to be a novel antagonist of ER/Golgi trafficking. This unique and well-conserved human norovirus motif is therefore an appealing target for antiviral drug development

Petrography and bulk composition of Miller Range 05035: a new lunar VLT gabbro

Miller Range (MIL) 05035 is a crystalline lunar mare gabbroic meteorite collected in Antarctica in 2005 [1]. It is an important new sample in the lunar meteorite (LM) collection as it is only one of ~8 to be classified as basaltic in nature. MIL 05035 is coarsely grained with large pyroxene grains ( 8mm) subophitically enclosing plagioclase grains ( 6mm), and accessory ilmenite, spinel, silica and sulphide phases

The 3D structure of the Lagrangian acceleration in turbulent flows

We report experimental results on the three dimensional Lagrangian acceleration in highly turbulent flows. Tracer particles are tracked optically using four silicon strip detectors from high energy physics that provide high temporal and spatial resolution. The components of the acceleration are shown to be statistically dependent. The probability density function (PDF) of the acceleration magnitude is comparable to a log-normal distribution. Assuming isotropy, a log-normal distribution of the magnitude can account for the observed dependency of the components. The time dynamics of the acceleration components is found to be typical of the dissipation scales whereas the magnitude evolves over longer times, possibly close to the integral time scale.Comment: accepted for publication in Physical Review Letter

Conclusions and questions from a non-randomised comparison of routine clinical services implementing different treatment models for borderline personality disorder

Our study (Barnicot & Crawford 2018) was a non-randomised comparison of outcomes in routine clinical services implementing different treatment models for borderline personality disorder (BPD): mentalization-based therapy (MBT) and dialectical behaviour therapy (DBT). Our study’s contribution lies primarily in its novelty as currently the only head-to-head comparison of these treatment models, and its potential to generate exploratory findings for further testing in a definitive randomised controlled trial. We thank Luyten and colleagues for their useful commentary

Detection of shocked atomic gas in the Kleinmann-Low nebula

The 63 micrometer (3)p(1)-(3)P(2) fine structure line emission of neutral atomic oxygen at the center of the Orion nebula with a resolution of 30" is presented. There are three main emission peaks. One is associated with the region of strongest thermal radio continuum radiation close to the Trapezium cluster, and probably arises at the interface between the HII region and the dense Orion molecular cloud. The other two line emission peaks, associated with the Kleinmann Low nebula, are similar in both distribution and velocity to those of the 2 micrometer S(1) line of molecular hydrogen and of the high velocity wings of rotational CO emission. The OI emission from the KL nebula can be produced in the shocked gas associated with the mass outflows in this region and is an important coolant of the shocked gas

Understanding the tsunami with a simple model

In this paper, we use the approximation of shallow water waves (Margaritondo G 2005 Eur. J. Phys. 26 401) to understand the behaviour of a tsunami in a variable depth. We deduce the shallow water wave equation and the continuity equation that must be satisfied when a wave encounters a discontinuity in the sea depth. A short explanation about how the tsunami hit the west coast of India is given based on the refraction phenomenon. Our procedure also includes a simple numerical calculation suitable for undergraduate students in physics and engineering