The sub-arcsecond hard X-ray structure of loop footpoints in a solar flare

The newly developed X-ray visibility forward fitting technique is applied to Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) data of a limb flare to investigate the energy and height dependence on sizes, shapes, and position of hard X-ray chromospheric footpoint sources. This provides information about the electron transport and chromospheric density structure. The spatial distribution of two footpoint X-ray sources is analyzed using PIXON, Maximum Entropy Method, CLEAN and visibility forward fit algorithms at nonthermal energies from $\sim 20$ to $\sim 200$ keV. We report, for the first time, the vertical extents and widths of hard X-ray chromospheric sources measured as a function of energy for a limb event. Our observations suggest that both the vertical and horizontal sizes of footpoints are decreasing with energy. Higher energy emission originates progressively deeper in the chromosphere consistent with downward flare accelerated streaming electrons. The ellipticity of the footpoints grows with energy from $\sim 0.5$ at $\sim 20$ keV to $\sim 0.9$ at $\sim 150$ keV. The positions of X-ray emission are in agreement with an exponential density profile of scale height $\sim 150$~km. The characteristic size of the hard X-ray footpoint source along the limb is decreasing with energy suggesting a converging magnetic field in the footpoint. The vertical sizes of X-ray sources are inconsistent with simple collisional transport in a single density scale height but can be explained using a multi-threaded density structure in the chromosphere.Comment: 7 pages, 7 figures, submitted to Ap

The influence of albedo on the size of hard X-ray flare sources

Context: Hard X-rays from solar flares are an important diagnostic of particle acceleration and transport in the solar atmosphere. Any observed X-ray flux from on-disc sources is composed of direct emission plus Compton backscattered photons (albedo). This affects both the observed spectra and images as well as the physical quantities derived from them such as the spatial and spectral distributions of accelerated electrons or characteristics of the solar atmosphere. Aims: We propose a new indirect method to measure albedo and to infer the directivity of X-rays in imaging using RHESSI data. Methods: Visibility forward fitting is used to determine the size of a disc event observed by RHESSI as a function of energy. This is compared to the sizes of simulated sources from a Monte Carlo simulation code of photon transport in the chromosphere for different degrees of downward directivity and true source sizes to find limits on the true source size and the directivity. Results: The observed full width half maximum of the source varies in size between 7.4 arcsec and 9.1 arcsec with the maximum between 30 and 40 keV. Such behaviour is expected in the presence of albedo and is found in the simulations. A source size smaller than 6 arcsec is improbable for modest directivities and the true source size is likely to be around 7 arcsec for small directivities. Conclusions: While it is difficult to image the albedo patch directly, the effect of backscattered photons on the observed source size can be estimated. The increase in source size caused by albedo has to be accounted for when computing physical quantities that include the size as a parameter such as flare energetics. At the same time, the study of the albedo signature provides vital information about the directivity of X-rays and related electrons.Comment: 8 pages, 6 figures, A&A (accepted

Instrumental oscillations in RHESSI count rates during solar flares

Aims: We seek to illustrate the analysis problems posed by RHESSI spacecraft motion by studying persistent instrumental oscillations found in the lightcurves measured by RHESSI's X-ray detectors in the 6-12 keV and 12-25 keV energy range during the decay phase of the flares of 2004 November 4 and 6. Methods: The various motions of the RHESSI spacecraft which may contribute to the manifestation of oscillations are studied. The response of each detector in turn is also investigated. Results: We find that on 2004 November 6 the observed oscillations correspond to the nutation period of the RHESSI instrument. These oscillations are also of greatest amplitude for detector 5, while in the lightcurves of many other detectors the oscillations are small or undetectable. We also find that the variation in detector pointing is much larger during this flare than the counterexample of 2004 November 4. Conclusions: Sufficiently large nutation motions of the RHESSI spacecraft lead to clearly observable oscillations in count rates, posing a significant hazard for data analysis. This issue is particularly problematic for detector 5 due to its design characteristics. Dynamic correction of the RHESSI counts, accounting for the livetime, data gaps, and the transmission of the bi-grid collimator of each detector, is required to overcome this issue. These corrections should be applied to all future oscillation studies.Comment: 8 pages, 10 figure

Temporal Correlation of Hard X-rays and Meter/Decimeter Radio Structures in Solar Flares

We investigate the relative timing between hard X-ray (HXR) peaks and structures in metric and decimetric radio emissions of solar flares using data from the RHESSI and Phoenix-2 instruments. The radio events under consideration are predominantly classified as type III bursts, decimetric pulsations and patches. The RHESSI data are demodulated using special techniques appropriate for a Phoenix-2 temporal resolution of 0.1s. The absolute timing accuracy of the two instruments is found to be about 170 ms, and much better on the average. It is found that type III radio groups often coincide with enhanced HXR emission, but only a relatively small fraction ($\sim$ 20%) of the groups show close correlation on time scales $<$ 1s. If structures correlate, the HXRs precede the type III emissions in a majority of cases, and by 0.69$\pm$0.19 s on the average. Reversed drift type III bursts are also delayed, but high-frequency and harmonic emission is retarded less. The decimetric pulsations and patches (DCIM) have a larger scatter of delays, but do not have a statistically significant sign or an average different from zero. The time delay does not show a center-to-limb variation excluding simple propagation effects. The delay by scattering near the source region is suggested to be the most efficient process on the average for delaying type III radio emission

X-Ray Polarization of Solar Flares Measured with Rhessi

The degree of linear polarization in solar flares has not yet been precisely determined despite multiple attempts to measure it with different missions. The high energy range in particular has very rarely been explored, due to its greater instrumental difficulties. We approached the subject using the Reuven Ramaty High Energy Spectroscopic Imager (RHESSI) satellite to study 6 X-class and 1 M-class flares in the energy range between 100 keV and 350 keV. Using RHESSI as a polarimeter requires the application of strict cuts to the event list in order to extract those photons that are Compton scattered between two detectors. Our measurements show polarization values between 2% and 54%, with errors ranging from 10% to 26% in 1 sigma level. In view of the large uncertainties in both the magnitude and direction of the polarization vector, the results can only reject source models with extreme properties.Comment: 26 pages, 11 figures, accepted for publication by Solar Physic

Women's empowerment, production choices, and crop diversity in Burkina Faso, India, Malawi, and Tanzania: a secondary analysis of cross-sectional data

BACKGROUND: Bolstering farm-level crop diversity is one strategy to strengthen food system resilience and achieve global food security. Women who live in rural areas play an essential role in food production; therefore, we aimed to assess the associations between women's empowerment and crop diversity. METHODS: In this secondary analysis of cross-sectional data, we used data from four cluster-randomised controlled trials done in Burkina Faso, India, Malawi, and Tanzania. We assessed women's empowerment using indicators from the Women's Empowerment in Agriculture Index. Farm-level crop diversity measures were the number of food crops grown, number of food groups grown, and if nutrient-dense crops were grown. We used a two-stage modelling approach. First, we analysed covariate-adjusted country-specific associations between women's empowerment and crop diversity indicators using multivariable generalised linear models. Second, we pooled country-specific associations using random-effects models. FINDINGS: The final analytic sample included 1735 women from Burkina Faso, 4450 women from India, 547 women from Malawi, and 574 women from Tanzania. Across all countries, compared with households in which women provided input into fewer productive decisions, households of women with greater input into productive decisions produced more food crops (mean difference 0·36 [95% CI 0·16-0·55]), a higher number of food groups (mean difference 0·16 [0·06-0·25]), and more nutrient-dense crops (percentage point difference 3 [95% CI 3-4]). Across all countries, each additional community group a woman actively participated in was associated with cultivating a higher number of food crops (mean difference 0·20 [0·04-0·35]) and a higher number of food groups (mean difference 0·11 [0·03-0·18]), but not more nutrient-dense crops. In pooled associations from Burkina Faso and India, asset ownership was associated with cultivating a higher number of food crops (mean difference 0·08 [0·04-0·12]) and a higher number of food groups (mean difference 0·05 [0·04-0·07]), but not more nutrient-dense crops. INTERPRETATION: Greater women's empowerment was associated with higher farm-level crop diversity among low-income agricultural households, suggesting that it could help enhance efforts to strengthen food system resilience. FUNDING: Bill & Melinda Gates Foundation

The Promoter of Rv0560c Is Induced by Salicylate and Structurally-Related Compounds in Mycobacterium tuberculosis

Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), is a major global health threat. During infection, bacteria are believed to encounter adverse conditions such as iron depletion. Mycobacteria synthesize iron-sequestering mycobactins, which are essential for survival in the host, via the intermediate salicylate. Salicylate is a ubiquitous compound which is known to induce a mild antibiotic resistance phenotype. In M. tuberculosis salicylate highly induces the expression of Rv0560c, a putative methyltransferase. We identified and characterized the promoter and regulatory elements of Rv0560c. PRv0560c activity was highly inducible by salicylate in a dose-dependent manner. The induction kinetics of PRv0560c were slow, taking several days to reach maximal activity, which was sustained over several weeks. Promoter activity could also be induced by compounds structurally related to salicylate, such as aspirin or para-aminosalicylic acid, but not by benzoate, indicating that induction is specific to a structural motif. The −10 and −35 promoter elements were identified and residues involved in regulation of promoter activity were identified in close proximity to an inverted repeat spanning the −35 promoter element. We conclude that Rv0560c expression is controlled by a yet unknown repressor via a highly-inducible promoter

The dUTPase Enzyme Is Essential in Mycobacterium smegmatis

Thymidine biosynthesis is essential in all cells. Inhibitors of the enzymes involved in this pathway (e.g. methotrexate) are thus frequently used as cytostatics. Due to its pivotal role in mycobacterial thymidylate synthesis dUTPase, which hydrolyzes dUTP into the dTTP precursor dUMP, has been suggested as a target for new antitubercular agents. All mycobacterial genomes encode dUTPase with a mycobacteria-specific surface loop absent in the human dUTPase. Using Mycobacterium smegmatis as a fast growing model for Mycobacterium tuberculosis, we demonstrate that dUTPase knock-out results in lethality that can be reverted by complementation with wild-type dUTPase. Interestingly, a mutant dUTPase gene lacking the genus-specific loop was unable to complement the knock-out phenotype. We also show that deletion of the mycobacteria-specific loop has no major effect on dUTPase enzymatic properties in vitro and thus a yet to be identified loop-specific function seems to be essential within the bacterial cell context. In addition, here we demonstrated that Mycobacterium tuberculosis dUTPase is fully functional in Mycobacterium smegmatis as it rescues the lethal knock-out phenotype. Our results indicate the potential of dUTPase as a target for antitubercular drugs and identify a genus-specific surface loop on the enzyme as a selective target