AirConstellations: In-Air Device Formations for Cross-Device Interaction via Multiple Spatially-Aware Armatures

AirConstellations supports a unique semi-fixed style of cross-device interactions via multiple self-spatially-aware armatures to which users can easily attach (or detach) tablets and other devices. In particular, AirConstellations affords highly flexible and dynamic device formations where the users can bring multiple devices together in-air - with 2-5 armatures poseable in 7DoF within the same workspace - to suit the demands of their current task, social situation, app scenario, or mobility needs. This affords an interaction metaphor where relative orientation, proximity, attaching (or detaching) devices, and continuous movement into and out of ad-hoc ensembles can drive context-sensitive interactions. Yet all devices remain self-stable in useful configurations even when released in mid-air. We explore flexible physical arrangement, feedforward of transition options, and layering of devices in-air across a variety of multi-device app scenarios. These include video conferencing with flexible arrangement of the person-space of multiple remote participants around a shared task-space, layered and tiled device formations with overview+detail and shared-to-personal transitions, and flexible composition of UI panels and tool palettes across devices for productivity applications. A preliminary interview study highlights user reactions to AirConstellations, such as for minimally disruptive device formations, easier physical transitions, and balancing "seeing and being seen"in remote work

Present-day stress indicators from a segment of the African-Eurasian plate boundary in the eastern Mediterranean Sea: Results of formation microscanner data

Ocean Drilling Program Leg 160 investigated two segments of the active African-Eurasian plate boundary in the Eastern Mediterranean Sea by shallow drilling: the Eratosthenes Seamount and the Mediterranean Ridge Olimpi mud volcano field. The borehole logging data acquired during Leg 160 were analyzed to obtain stress indicators and a better definition of the present-day stress situation in the Eastern Mediterranean. Both borehole breakout zones (borehole enlargements) and vertical drilling-induced fractures were identified from borehole geometry data recorded using the Formation MicroScanner (FMS) tool and from computer-generated FMS images, respectively. For Holes 966F and 967E at the Eratosthenes Seamount, the enlargements and the drilling-induced fractures show the same orientation. If both were stress induced and representative of the present-day stress orientation, they would be 90°off. A comparison of the strike of the inferred borehole enlargements with the observed paleostress-related fracturing suggests the possibility that borehole enlargements might be aligned with the strike of some of the structures. Thus, we derive the stress orientation at the Eratosthenes Seamount sites from drilling-induced fractures alone. The orientation of the maximum horizontal principal stress, S(H), is about N50°E for Hole 966F, located on the seamount plateau, and N30°E for Hole 967E, located on the northern slope of the Eratosthenes Seamount. For Hole 965A, also on the slope but at a shallower depth, the orientation obtained is about N170°E. The stress orientations obtained from borehole enlargements and from the vertical drilling-induced fractures in Hole 970A, on the eastern flank of the Milano mud volcano, show consistent, nearly north-south, orientations of S(H).Peer Reviewe

Beziehung der Permeabilitaet von Kluftsystemen zum regionalen Spannungsfeld Abschlussbericht

With 20 mapsAvailable from TIB Hannover: F97B812 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

Pulmonary CCR2⁺CD4⁺  T cells are immune regulatory and attenuate lung fibrosis development.

BACKGROUND: Animal models have suggested that CCR2-dependent signalling contributes to the pathogenesis of pulmonary fibrosis, but global blockade of CCL2 failed to improve the clinical course of patients with lung fibrosis. However, as levels of CCR2(+)CD4(+) T cells in paediatric lung fibrosis had previously been found to be increased, correlating with clinical symptoms, we hypothesised that distinct CCR2(+) cell populations might either increase or decrease disease pathogenesis depending on their subtype. OBJECTIVE: To investigate the role of CCR2(+)CD4(+) T cells in experimental lung fibrosis and in patients with idiopathic pulmonary fibrosis and other fibrosis. METHODS: Pulmonary CCR2(+)CD4(+) T cells were analysed using flow cytometry and mRNA profiling, followed by in silico pathway analysis, in vitro assays and adoptive transfer experiments. RESULTS: Frequencies of CCR2(+)CD4(+) T cells were increased in experimental fibrosis-specifically the CD62L(-)CD44(+) effector memory T cell phenotype, displaying a distinct chemokine receptor profile. mRNA profiling of isolated CCR2(+)CD4(+) T cells from fibrotic lungs suggested immune regulatory functions, a finding that was confirmed in vitro using suppressor assays. Importantly, adoptive transfer of CCR2(+)CD4(+) T cells attenuated fibrosis development. The results were partly corroborated in patients with lung fibrosis, by showing higher percentages of Foxp3(+) CD25(+) cells within bronchoalveolar lavage fluid CCR2(+)CD4(+) T cells as compared with CCR2(-)CD4(+) T cells. CONCLUSION: Pulmonary CCR2(+)CD4(+) T cells are immunosuppressive, and could attenuate lung inflammation and fibrosis. Therapeutic strategies completely abrogating CCR2-dependent signalling will therefore also eliminate cell populations with protective roles in fibrotic lung disease. This emphasises the need for a detailed understanding of the functions of immune cell subsets in fibrotic lung disease

Interactions between thin- and thick-skinned tectonics at the northwestern front of the Jura fold-and-thrust belt (eastern France)

International audienc