95 research outputs found
Effect of steroid hormones on lipid metabolism and ABCd trasporters in the neurodegenerative disease x-linked adrenoleukodystrophy
Arsenic movement and fractionation in agricultural soils which received wastewater from an adjacent industrial site for 50 years
Arsenic (As) is an element with important environmental and human health implications due to its toxic properties. It is naturally occurring since it is contained in minerals, but it can also be enriched and distributed in the environment by anthropogenic activities. This paper reports on the historic As contamination of agricultural soils in one of the most important national relevance site for contamination in Italy, the so-called SIN Brescia-Caffaro, in the city of Brescia, northern Italy. These agricultural areas received As through the use of irrigation waters from wastewater coming from a factory of As-based pesticides (lead and calcium arsenates, sodium arsenite). Pesticide production started in 1920 and ended in the '70. Concentrations in the areas are generally beyond the legal threshold values for different soil uses and are up to >200 mg/kg. Arsenic contamination was studied to assess the long-time trend and the dynamics related to the vertical movement of As down to 1 m depth and its horizontal diffusion with surface irrigation in the entire field. Arsenic fractionation analysis (solid phase speciation by sequential extraction procedure) was also performed on samples collected from these areas and employed in greenhouse experiments with several plant species to evaluate the long-term contamination and the role of plant species in modifying As availability in soil. The results of this work can help in the evaluation of the conditions controlling the vertical transfer of As towards surface aquifers, the bioaccumulation likelihood in the agricultural food chain and the selection of sustainable remediation techniques such as phytoextraction
Habitats Directive in northern Italy: a series of proposals for habitat definition improvement
Habitats Directive (92/43/EEC) is the cornerstone of nature conservation in Europe and is at the core of the EU Biodiversity Strategy for 2030. There is room, however, for its improvement, at least for northern Italy, where ambiguities in the definition of habitat types of Annex I of the Habitats Directive are not novel and interpretation difficulties have been highlighted. Sharpening the characterization of habitat types represents an opportunity for lowering classification uncertainties and improving conservation success. With the aim to refine the definitions of habitat types and associated typical species of the Habitats Directive, a group of vegetation scientists of the Italian Society of Vegetation Science based in northern Italy made the exercise of finding viable proposals for those habitat types having a problematic interpretation in the Alpine biogeographical region of Italy. Such proposals arise from group discussions among scientists, and professionals, thus offering a shared view. We prepared 9 habitat proposals important for this geographic area. They include new habitat types at the European level, new subtypes within pre-existing habitat types, including some adjustments of the recently proposed subtypes with respect to northern Italy, and recognition of priority criteria for a pre-existing habitat type. With a vision of tailored conservation, our proposals represent a starting point in view of a future update of Annex I. Furthermore, the list of typical species could be useful for preparing expert systems for automatic classification. Irrespective of legally binding solutions in place, we caution these proposals represent relevant baseline conservation indications that local and regional administrations of the Alpine Arch should consider
Fibroblasts from patients with Diamond-Blackfan anaemia show abnormal expression of genes involved in protein synthesis, amino acid metabolism and cancer
Background: Diamond-Blackfan anaemia (DBA) is a rare inherited red cell hypoplasia characterised by a defect in the maturation of erythroid progenitors and in some cases associated with malformations. Patients have an increased risk of solid tumors. Mutations have been found in several ribosomal protein (RP) genes, i.e RPS19, RPS24, RPS17, RPL5, RPL11, RPL35A. Studies in haematopoietic progenitors from patients show that haplo-insufficiency of an RP impairs rRNA processing and ribosome biogenesis. DBA lymphocytes show reduced protein synthesis and fibroblasts display abnormal rRNA processing and impaired proliferation. Results: To evaluate the involvement of non-haematopoietic tissues in DBA, we have analysed global gene expression in fibroblasts from DBA patients compared to healthy controls. Microarray expression profiling using Affymetrix GeneChip Human Genome U133A 2.0 Arrays revealed that 421 genes are differentially expressed in DBA patient fibroblasts. These genes include a large cluster of ribosomal proteins and factors involved in protein synthesis and amino acid metabolism, as well as genes associated to cell death, cancer and tissue development. Conclusion: This analysis reports for the first time an abnormal gene expression profile in a non-haematopoietic cell type in DBA. These data support the hypothesis that DBA may be due to a defect in general or specific protein synthesis. \ua9 2009 Avondo et al; licensee BioMed Central Ltd
Global and regional IUCN Red List assessments: 7
In this contribution, the conservation status assessment of four vascular plants according to IUCN categories
and criteria are presented. It includes the assessments of Aurinia leucadea (Guss.) K.Koch, Chondrilla chondrilloides
(Ard.) H.Karst., Daphne cneorum L., and Ophioglossum azoricum C.Presl at regional level (Italy)
The invasion history of Elodea canadensis and E. nuttallii (Hydrocharitaceae) in Italy from herbarium accessions, field records and historical literature
We analysed the invasion history of two North American macrophytes (Elodea canadensis and E. nuttallii) in Italy, through an accurate census of all available herbarium and field records, dating between 1850 and 2019, and a rich literature collection describing the initial introduction and naturalisation phase that supports the results obtained by the occurrence records. Elodea canadensis arrived in Italy before 1866 and had two invasion phases, between the 1890s and 1920s and between the 1990s and 2000s; E. nuttallii, probably arrived in the 1970s, started invading in 2000 and the invasion is still ongoing. Botanical gardens and fish farming played a crucial role in dispersal and naturalisation of both species. The current invasion range of both species is centred in northern Italy, with scattered occurrences of E. canadensis in central and southern regions. River Po represents a dispersal barrier to the Mediterranean region and a strategic monitoring site to prevent the invasion in the peninsula. The study detects differences in the niches of the two species during the introduction and naturalisation phase and a habitat switch occurred after 1980 in E. canadensis and after 2000 in E. nuttallii, during their expansion phases. For E. canadensis the switch corresponds to the second invasion round. Further research can clarify whether the second invasion round is due to confusion of the recently introduced E. nuttallii with E. canadensis, to a cryptic introduction of a new genotype, to post-introduction evolution, or just to an increased scientific interest in biological invasions
The chemical and biological response of two remote mountain lakes in the Southern Central Alps (Italy) to twenty years of changing physical and chemical climate
Two small high mountain lakes in the Alps were monitored in 1984-2003 to follow their response to changes in human impact, such as deposition of atmospheric pollutants, fish stocking and climate change. The results were compared to occasional samplings performed in the 1940s, and to the remains found in sediment cores. When monitoring started, the most acid-sensitive of them, Lake Paione Superiore, was acidified, with evident effects in its flora and fauna: benthic diatoms assemblage was shifted towards aci- dophilous species, and zooplankton lost the dominant species, Arctodiaptomus alpinus. Palaeolimnological studies outlined that lake acidification paralleled the increasing input of long-range transported industrial pollutants, traced by spherical carbonaceous parti- cles. On the contrary, the biota of Lake Paione Inferiore appeared to be mainly affected by fish stocking. In the last twenty years, de- crease in acid load from the atmosphere led to an improvement in lake water quality, with an increase in both pH and alkalinity. First signs of biological recovery were identified, such as change in diatom flora and appearance of sensitive species among benthic insects. However, climate change and episodic deposition of Saharan dust were important driving factors controlling lake water chemistry. Further monitoring to assess the effects of climate change and of the increasing load of nitrogen and other pollutants is recommended. Key word: atmospheric deposition, acidification, plankton, benthos, diatom
First overview on the 4th Annex I Habitats Report in Italy: methods, criticality, results and future prospects
Like all the other EU/28 countries, in 2019 Italy developed the 4th Italian Report
ex-Art. 17 on the conservation status of the Habitats of Annex I to the 92/43/EEC
Directive. Institutional referent of the process, on behalf of the Ministry for
Environment, Land and Sea Protection (MATTM), was the Italian Institute for
Environmental Protection and Research (ISPRA) with the scientific support of the
Italian Botanical Society (SBI). A huge working group composed of thematic and
territorial experts was formed with the task to collect, analyse, validate the data
resulting from Annex I Habitat monitoring in Italy for the period 2013-2018, whose
collection is in charge to the regional administrations. Data on 124 types of terrestrial
and inland water Habitats present in Italy have been processed in order to assess their
overall conservation status in the Biogeographic Regions of occurrence. The carried out
activity led to the compilation of 278 assessment sheets. The work included a critical
analysis of the data and a broad scientific confrontation aimed at finding
methodologically robust solutions to fill the gaps. The work was structured so as to
guarantee the traceability of the information and to allow the collection of "gray"
literature and scientific articles, phytosociological surveys and unpublished material of
the specialists, composing a substantial pool of data useful for starting a long-term
process to support the next reporting cycles. Cartographic outcomes, associated
databases and additional data used for the assessments will be available online on the
ISPRA Portal as soon as the validation process by the European Commission will be
completed. A freely accessible online archive of phytosociological surveys
representative of the various Annex I Habitats in Italy is being set up within the national
"VegItaly" database, managed by the Italian Society of Vegetation Science, by way of a
dedicated archive named "HAB_IT". Such a long-term vision, oriented to the storage
and enhancement of knowledge, represents an important innovative aspect and a
significant progress towards the construction of an effective monitoring system for the
conservation of Annex I Habitats in Italy
Il Reporting ex-Art. 17 degli Habitat di All. I alla Direttiva 92/43/CEE in Italia: metodi, criticità, stato dell'arte e prospettive future.
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