597 research outputs found
New insights into pedestrian flow through bottlenecks
Capacity estimation is an important tool for the design and dimensioning of
pedestrian facilities. The literature contains different procedures and
specifications which show considerable differences with respect to the
estimated flow values. Moreover do new experimental data indicate a stepwise
growing of the capacity with the width and thus challenge the validity of the
specific flow concept. To resolve these differences we have studied
experimentally the unidirectional pedestrian flow through bottlenecks under
laboratory conditions. The time development of quantities like individual
velocities, density and individual time gaps in bottlenecks of different width
is presented. The data show a linear growth of the flow with the width. The
comparison of the results with experimental data of other authors indicates
that the basic assumption of the capacity estimation for bottlenecks has to be
revised. In contradiction with most planning guidelines our main result is,
that a jam occurs even if the incoming flow does not overstep the capacity
defined by the maximum of the flow according to the fundamental diagram.Comment: Traffic flow, pedestrian traffic, crowd dynamics, capacity of
bottlenecks (16 pages, 8 figures); (+ 3 new figures and minor revisions
Model-based Aeroservoelastic Design and Load Alleviation of Large Wind Turbine Blades
This paper presents an aeroservoelastic modeling approach for dynamic load alleviation
in large wind turbines with trailing-edge aerodynamic surfaces. The tower, potentially on a
moving base, and the rotating blades are modeled using geometrically non-linear composite
beams, which are linearized around reference conditions with arbitrarily-large structural
displacements. Time-domain aerodynamics are given by a linearized 3-D unsteady vortexlattice
method and the resulting dynamic aeroelastic model is written in a state-space
formulation suitable for model reductions and control synthesis. A linear model of a single
blade is used to design a Linear-Quadratic-Gaussian regulator on its root-bending moments,
which is finally shown to provide load reductions of about 20% in closed-loop on the full
wind turbine non-linear aeroelastic model
Configuration development study of the X-24C hypersonic research airplane
Bottom line results were made of a three-phase study to determine the feasibility of designing, building, and operating, and maintaining an air-launched high performance aircraft capable of cruising at speeds up to Mach 8 for short durations. The results show that Lockalloy heat-sink structure affords the capability for a 'work-horse' vehicle which can serve as an excellent platform for this research. It was further concluded that the performance of a blended wing body configuration surpassed that of a lifting body design for typical X-24C missions. The cost of a two vehicle program, less engines, B-52 modification and contractor support after delivery, can be kept within $70M (in Jan. 1976 dollars)
In cellulo serial crystallography of alcohol oxidase crystals inside yeast cells
The possibility of using femtosecond pulses from an X-ray free-electron laser to collect diffraction data from protein crystals formed in their native cellular organelle has been explored. X-ray diffraction of submicrometre-sized alcohol oxidase crystals formed in peroxisomes within cells of genetically modified variants of the methylotrophic yeast Hansenula polymorpha is reported and characterized. The observations are supported by synchrotron radiation-based powder diffraction data and electron microscopy. Based on these findings, the concept of in cellulo serial crystallography on protein targets imported into yeast peroxisomes without the need for protein purification as a requirement for subsequent crystallization is outlined
Structural basis of dimerization and nucleic acid binding of human DBHS proteins NONO and PSPC1.
The Drosophila behaviour/human splicing (DBHS) proteins are a family of RNA/DNA binding cofactors liable for a range of cellular processes. DBHS proteins include the non-POU domain-containing octamer-binding protein (NONO) and paraspeckle protein component 1 (PSPC1), proteins capable of forming combinatorial dimers. Here, we describe the crystal structures of the human NONO and PSPC1 homodimers, representing uncharacterized DBHS dimerization states. The structures reveal a set of conserved contacts and structural plasticity within the dimerization interface that provide a rationale for dimer selectivity between DBHS paralogues. In addition, solution X-ray scattering and accompanying biochemical experiments describe a mechanism of cooperative RNA recognition by the NONO homodimer. Nucleic acid binding is reliant on RRM1, and appears to be affected by the orientation of RRM1, influenced by a newly identified 'β-clasp' structure. Our structures shed light on the molecular determinants for DBHS homo- and heterodimerization and provide a basis for understanding how DBHS proteins cooperatively recognize a broad spectrum of RNA targets
Nuclear and Particle Physics applications of the Bohm Picture of Quantum Mechanics
Approximation methods for calculating individual particle/ field motions in
spacetime at the quantum level of accuracy (a key feature of the Bohm Picture
of Quantum Mechanics (BP)), are studied. Modern textbook presentations of
Quantum Theory are used throughout, but only to provide the necessary, already
existing, tested formalisms and calculational techniques. New coherent
insights, reinterpretations of old solutions and results, and new (in principle
testable) quantitative and qualitative predictions, can be obtained on the
basis of the BP that complete the standard type of postdictions and
predictions.Comment: 41 page
Recommended from our members
OC3 -- Benchmark Exercise of Aero-Elastic Offshore Wind Turbine Codes: Preprint
This paper introduces the work content and status of the first international investigation and verification of aero-elastic codes for offshore wind turbines as performed by the "Offshore Code Comparison Collaboration" (OC3) within the "IEA Wind Annex XXIII -- Subtask 2"
Quantum mechanics: Myths and facts
A common understanding of quantum mechanics (QM) among students and practical
users is often plagued by a number of "myths", that is, widely accepted claims
on which there is not really a general consensus among experts in foundations
of QM. These myths include wave-particle duality, time-energy uncertainty
relation, fundamental randomness, the absence of measurement-independent
reality, locality of QM, nonlocality of QM, the existence of well-defined
relativistic QM, the claims that quantum field theory (QFT) solves the problems
of relativistic QM or that QFT is a theory of particles, as well as myths on
black-hole entropy. The fact is that the existence of various theoretical and
interpretational ambiguities underlying these myths does not yet allow us to
accept them as proven facts. I review the main arguments and counterarguments
lying behind these myths and conclude that QM is still a
not-yet-completely-understood theory open to further fundamental research.Comment: 51 pages, pedagogic review, revised, new references, to appear in
Found. Phy
Determination of the b quark mass at the M_Z scale with the DELPHI detector at LEP
An experimental study of the normalized three-jet rate of b quark events with
respect to light quarks events (light= \ell \equiv u,d,s) has been performed
using the CAMBRIDGE and DURHAM jet algorithms. The data used were collected by
the DELPHI experiment at LEP on the Z peak from 1994 to 2000. The results are
found to agree with theoretical predictions treating mass corrections at
next-to-leading order. Measurements of the b quark mass have also been
performed for both the b pole mass: M_b and the b running mass: m_b(M_Z). Data
are found to be better described when using the running mass. The measurement
yields: m_b(M_Z) = 2.85 +/- 0.18 (stat) +/- 0.13 (exp) +/- 0.19 (had) +/- 0.12
(theo) GeV/c^2 for the CAMBRIDGE algorithm. This result is the most precise
measurement of the b mass derived from a high energy process. When compared to
other b mass determinations by experiments at lower energy scales, this value
agrees with the prediction of Quantum Chromodynamics for the energy evolution
of the running mass. The mass measurement is equivalent to a test of the
flavour independence of the strong coupling constant with an accuracy of 7
permil.Comment: 24 pages, 10 figures, Accepted by Eur. Phys. J.
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