150 research outputs found

    Tratamiento de las fracturas conminutas de cabeza radial mediante exéresis cabeza radial: resultados a largo plazo de 18 casos

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    La resección de la cabeza radial en las fracturas conminutas supone una opción de tratamiento comúnmente aceptada. El objetivo de este estudio es la evolución de los resultados a largo plazo tras escisión de la cabeza radial. Se realizó un estudio prospectivo en 18 pacientes con fracturas Mason tipo III y IV. La media de edad fue de 50 años con un tiempo medio de seguimiento de 6,8 años. Sólo 4 pacientes presentaron una pérdida de 15 grados o más de la extensión. Se produjo una pérdida den la pronación y supinación de 3,7º y 8,4 respectivamente. De acuerdo a la clasificación funcional utilizada, la media según EMPS fue de 83,3 con un 88,3% de resultados satisfactorios y según la HSSS la media fue de 71,1 con un 94% de excelentes o buenos resultados.Radial head resection is the accepted treatment of comminuted radial-head fractures in adults. The purpose of the present study was to evaluate the long-term outcomes of primary radial head excision. A retrospective study was undertaken of 18 patients with Mason type III and IV. The average age at operation was 50 years and the average length of follow-up was 6,8 years. Only four patients lost 15 degrees or more of extension of the elbow. Pronation and supination were decreased by an average of 3,7º and 8,4º respective. According to the functional classification that we use, the average of EMPS score was 83,3 with a 88,3% of satisfactory results and the average of HSSS score was 71,1 with a 94% of excellent o good results

    Noninvasive assessment of an engineered bioactive graft in myocardial infarction: impact on cardiac function and scar healing

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    Cardiac tissue engineering, which combines cells and biomaterials, is promising for limiting the sequelae of myocardial infarction (MI). We assessed myocardial function and scar evolution after implanting an engineered bioactive impedance graft (EBIG) in a swine MI model. The EBIG comprises a scaffold of decellularized human pericardium, green fluorescent protein-labeled porcine adipose tissue-derived progenitor cells (pATPCs), and a customized-design electrical impedance spectroscopy (EIS) monitoring system. Cardiac function was evaluated noninvasively by using magnetic resonance imaging (MRI). Scar healing was evaluated by using the EIS system within the implanted graft. Additionally, infarct size, fibrosis, and inflammation were explored by histopathology. Upon sacrifice 1 month after the intervention, MRI detected a significant improvement in left ventricular ejection fraction (7.5%64.9% vs. 1.4%63.7%; p = .038) and stroke volume (11.565.9 ml vs. 364.5 ml; p = .019) in EBIG-treated animals. Noninvasive EIS data analysis showed differences in both impedance magnitude ratio (20.02 6 0.04 per day vs. 20.48 6 0.07 per day; p = .002) and phase angle slope (20.18°60.24° per day vs.23.52°60.84° per day; p = .004) in EBIG compared with control animals. Moreover, in EBIG-treated animals, the infarct size was 48% smaller (3.4%60.6% vs. 6.5%61%; p = .015), less inflammation was found by means of CD25+ lymphocytes (0.65 6 0.12 vs. 1.26 6 0.2; p = .006), and a lower collagen I/III ratio was detected (0.4960.06 vs. 1.6660.5; p = .019). An EBIG composed of acellular pericardium refilled with pATPCs significantly reduced infarct size and improved cardiac function in a preclinical model of MI. Noninvasive EIS monitoring was useful for tracking differential scar healing in EBIG-treated animals, which was confirmed by less inflammation and altered collagen deposit.Peer ReviewedPostprint (published version

    Influences of synoptic situation and teleconnections on fog-water collection in the Mediterranean Iberian Peninsula, 2003-2012

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    Fog-water collection has been widely analysed for its quantification and potential uses; however, there are few studies assessing the synoptic conditions and largescale teleconnection patterns that affect its occurrence. Focusing on the Mediterranean Iberian Peninsula, this work aims to analyse the synoptic patterns, both at surface level and 850 hPa geopotential height, that most likely to favour fogwater collection, and to quantify the relationship between fog-water collection and the NAOi (North Atlantic Oscillation index), MOi (Mediterranean Oscillation index) as well as WeMOi (Western Mediterranean Oscillation index) teleconnection patterns. For this purpose, daily fog-water observations from a dense network of 23 fog-water collectors located along the Mediterranean Iberian Peninsula for 2003-2012 were analysed in relation to synoptic patterns and the threeteleconnection indices. The major findings are: (a) The most favourable synoptic patterns for fog-water collection are maritime advections carrying humidity from the Mediterranean basin, and cyclonic circulations, whereas anti-cyclonic situations generally led to large number of foggy days with low fog-collection rates. (b) In terms of winds at 850 hPa, the most favourable low-level flows for fogwater collection are associated with strong winds (>5.1 m s−1) from theMediterranean. Atlantic winds generally cause a greater number of fog days than Mediterranean winds, with less fog-water collection rates. (c) WeMOi has the greatest influence on fog-water collection, mainly during winter and spring months, with statistically significant negative relationships for most of the stations. MOi also shows a great influence, with a large number of statistically significant negative correlations, mainly during the same months as WeMOi. Lastly, NAOi presented the lowest and no significant negative correlations with fog-water collection

    Predicting the onset and persistence of episodes of depression in primary health care. The predictD-Spain study: Methodology

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    Background: The effects of putative risk factors on the onset and/or persistence of depression remain unclear. We aim to develop comprehensive models to predict the onset and persistence of episodes of depression in primary care. Here we explain the general methodology of the predictD-Spain study and evaluate the reliability of the questionnaires used. Methods: This is a prospective cohort study. A systematic random sample of general practice attendees aged 18 to 75 has been recruited in seven Spanish provinces. Depression is being measured with the CIDI at baseline, and at 6, 12, 24 and 36 months. A set of individual, environmental, genetic, professional and organizational risk factors are to be assessed at each follow-up point. In a separate reliability study, a proportional random sample of 401 participants completed the test-retest (251 researcher-administered and 150 self-administered) between October 2005 and February 2006. We have also checked 118,398 items for data entry from a random sample of 480 patients stratified by province. Results: All items and questionnaires had good test-retest reliability for both methods of administration, except for the use of recreational drugs over the previous six months. Cronbach's alphas were good and their factorial analyses coherent for the three scales evaluated (social support from family and friends, dissatisfaction with paid work, and dissatisfaction with unpaid work). There were 191 (0.16%) data entry errors. Conclusion: The items and questionnaires were reliable and data quality control was excellent. When we eventually obtain our risk index for the onset and persistence of depression, we will be able to determine the individual risk of each patient evaluated in primary health car

    Nanoscale magnetic structure and properties of solution-derived self-assembled La0.7Sr0.3MnO3 islands

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    The following article appeared in Journal of Applied Physics 111.2 (2012): 024307 and may be found at http://scitation.aip.org/content/aip/journal/jap/111/2/10.1063/1.3677985Strain-induced self-assembled La0.7Sr0.3MnO 3 nanoislands of lateral size 50-150 nm and height 10-40 nm have been grown on yttria-stabilized zirconia (001)-substrates from ultradiluted chemical solutions based on metal propionates. The nanoislands grow highly relaxed withstanding the epitaxial relation (001)LSMO[110]//(001) Ysz[010] and show bulk-like average magnetic properties in terms of Curie temperature and saturation magnetization. The interplay of the magnetocrystalline and shape anisotropy within the nanoisland ensemble results in an in-plane magnetic anisotropy with a magnetocrystalline constant K 1(150K) = -(5±1) kJ/m3 and in-plane easy axis along the [110] -La0.7Sr0.3MnO3 direction as measured, for the first time, through ferromagnetic resonance experiments. Magnetic force microscopy studies reveal the correlation between nanoisland size and its magnetic domain structure in agreement with micromagnetic simulations. In particular, we have established the required geometric conditions for single domain, multidomain, and vortex configurations.We acknowledge the financial support from MEC (MAT2008-01022, Consolider NANOSELECT and FPU), Comunidad Autónoma de Madrid (CAM S2009/MAT-1467), Generalitat de Catalunya (Catalan Pla de Recerca 2009-SGR- 770 and XaRMAE), and EU (NESPA). R. D. Zysler and C. A. Ramos acknowledge support from PIP-1333(2007) CONICET and PICT 829 (2006) and PICT 832(2006) ANPCyT of Argentina. Serveis Científic-Tècnics from Universitat de Barcelona and Servei de Micròscopia from Universitat Auto`noma de Barcelona are acknowledged for TEM facilities

    Cuidados familiares prestados por los ancianos del ámbito rural a distintas generaciones

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    Objectives: To describe the profile of caregivers higher in rural areas, to analyze sociodemographic differences in health and social relations between family caregivers and non-caregivers, and service needs unmet. Methodology: We surveyed 787 people over 64 noninstitutionalized belonging to the Basic Health Area of Zaragoza. Variables were collected through the questionnaire OARS-MAFQ (OARS): sociodemographic, need for services, assessment of social, economic and physical health. Other variables were: functional capacity for activities of daily living, basic and instrumental, body mass index and physical activity undertaken. Results: All caregivers of children/grandchildren were independent for activities of daily living, performed more physically active, had good physical and so perceived. Noncaregivers had the highest proportion of dependence and depression. The three groups had good social and economic resources, although significantly higher in those who care for children/grandchildren in which needs were perceived as more public transport and travel more. Non-caregivers reported more need for help with bathing, dressing, household chores and meal preparation. Caregivers of spouses/parents needed more treatment to personal or family problems. There was a great need for nursing care in the three groups. Conclusions: The profile, characteristics and needs of caregiver and no-caregiver were different, coinciding only in high need for nursing care

    Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial

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    Background: In the predictD-intervention, GPs used a personalised biopsychosocial programme to prevent depression. This reduced the incidence of major depression by 21.0%, although the results were not statistically significant. Aim: To determine whether the predictD-intervention is effective at preventing anxiety in primary care patients without depression or anxiety. Design and setting: Secondary study of a cluster randomised trial with practices randomly assigned to either the predictD-intervention or usual care. This study was conducted in seven Spanish cities from October 2010 to July 2012. Method: In each city, 10 practices and two GPs per practice, as well as four to six patients every recruiting day, were randomly selected until there were 26–27 eligible patients for each GP. The endpoint was cumulative incidence of anxiety as measured by the PRIME-MD screening tool over 18 months. Results: A total of 3326 patients without depression and 140 GPs from 70 practices consented and were eligible to participate; 328 of these patients were removed because they had an anxiety syndrome at baseline. Of the 2998 valid patients, 2597 (86.6%) were evaluated at the end of the study. At 18 months, 10.4% (95% CI = 8.7% to 12.1%) of the patients in the predictD-intervention group developed anxiety compared with 13.1% (95% CI = 11.4% to 14.8%) in the usual-care group (absolute difference = −2.7% [95% CI = −5.1% to −0.3%]; P = 0.029). Conclusion: A personalised intervention delivered by GPs for the prevention of depression provided a modest but statistically significant reduction in the incidence of anxiety
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