Cyclic codes over {Z_2+ uZ_2+ u^ 2Z_2+\ldots+ u^{k-1} Z_2}

In this paper, we study the structure of cyclic codes of an arbitrary length n over the ring Z_2+ uZ_2+ u^ 2Z_2+\ldots+ u^{k-1} Z_2, where u^ k= 0. Also we study the rank for these codes, and we find their minimal spanning sets. This study is a generalization and extension of the work in reference [1]

Study of magnetic nanovectors by Wet-STEM, a new ESEM mode in transmission

International audienc

Radionuclides delivery systems for nuclear imaging and radiotherapy of cancer

The recent developments of nuclear medicine in oncology have involved numerous investigations of novel specific tumor-targeting radiopharmaceuticals as a major area of interest for both cancer imaging and therapy. The current progress in pharmaceutical nanotechnology field has been exploited in the design of tumor-targeting nanoscale and microscale carriers being able to deliver radionuclides in a selective manner to improve the outcome of cancer diagnosis and treatment. These carriers include chiefly, among others, liposomes, microparticles, nanoparticles, micelles, dendrimers and hydrogels. Furthermore, combining the more recent nuclear imaging multimodalities which provide high sensitivity and anatomical resolution such as PET/CT (positron emission tomography/computed tomography) and SPECT/CT (combined single photon emission computed tomography/computed tomography system) with the use of these specific tumor-targeting carriers constitutes a promising rally which will, hopefully in the near future, allow for earlier tumor detection, better treatment planning and more powerful therapy. In this review, we highlight the use, limitations, advantages and possible improvements of different nano- and microcarriers as potential vehicles for radionuclides delivery in cancer nuclear imaging and radiotherapy

Formulation of stable detoxifying w/o/w reactive multiple emulsions: in vitro evaluation

International audienceOver the last decade, acute drug intoxications have been known to be a serious threat to the public health field. Nevertheless, only a few means of imperfect detoxication treatments have, unfortunately, been applied to date. This paper presents water-in-oil-in-water (w/o/w) reactive multiple emulsions (ME) as an efficient method of in vitro detoxication against Nivaquine, a drug widely accused of being used in suicide attempts. The detoxication efficiency of these emulsions is attributed to the use of an adequate extractant-trapping agent couple giving a good extraction yield. Interestingly, some prepared emulsions showed a Nivaquine extraction yield of about 85%. A series of studies was conducted to recognize the effect of the preparation protocol, the emulsion ingredients, especially the extractant-trapping agent couple, and the experimental conditions on the extraction output. The extraction yield increases with the concentration of the extractant and with the alcalinization of the extraction medium. Globally, these reactive multiple emulsions have shown to be stable and highly detoxifying against Nivaquine taken as a toxic molecule model. Moreover, the process of Nivaquine extraction by the extractant in the oily phase and its trapping in the internal aqueous phase has been elucidated and validated