An empirical investigation of an object-oriented software system

This is the post print version of the article. The official published version can be obtained from the link below.This paper describes an empirical investigation into an industrial object-oriented (OO) system comprised of 133,000 lines of C++. The system was a subsystem of a telecommunications product and was developed using the Shlaer-Mellor method. From this study, we found that there was little use of OO constructs such as inheritance and, therefore, polymorphism. It was also found that there was a significant difference in the defect densities between those classes that participated in inheritance structures and those that did not, with the former being approximately three times more defect-prone. We were able to construct useful prediction systems for size and number of defects based upon simple counts such as the number of states and events per class. Although these prediction systems are only likely to have local significance, there is a more general principle that software developers can consider building their own local prediction systems. Moreover, we believe this is possible, even in the absence of the suites of metrics that have been advocated by researchers into OO technology. As a consequence, measurement technology may be accessible to a wider group of potential users

Some First Results for Noncooperative Pregames : Social Conformity and Equilibrium in Pure Strategies.

We introduce the framework of noncooperative pregames and demonstrate that for all games with sufficiently many players, there exists approximate (E) Nash equilibria in pure strategies. Moreover, an equilibrium can be selected with the property that most players choose the same strategies as all other players with similar attributes. More precisely, there is an integer K, depending on E but not on the number of players so that any sufficiently large society can be partitioned into fewer than K groups, or cultures, consisting of similar players, and all players in the same group play the same pure strategy. In ongoing research we are extending the model to cover a broader class of situations, including incomplete information.GAMES ; INFORMATION ; STRATEGIC PLANNING

Global Diffusion in a Realistic Three-Dimensional Time-Dependent Nonturbulent Fluid Flow

We introduce and study the first model of an experimentally realizable three-dimensional time-dependent nonturbulent fluid flow to display the phenomenon of global diffusion of passive-scalar particles at arbitrarily small values of the nonintegrable perturbation. This type of chaotic advection, termed {\it resonance-induced diffusion\/}, is generic for a large class of flows.Comment: 4 pages, uuencoded compressed postscript file, to appear in Phys. Rev. Lett. Also available on the WWW from http://formentor.uib.es/~julyan/, or on paper by reques

Uterine spiral artery remodeling involves endothelial apoptosis induced by extravillous trophoblasts through Fas/FasL interactions.

Objective— Invasion of uterine spiral arteries by extravillous trophoblasts in the first trimester of pregnancy results in loss of endothelial and musculoelastic layers. This remodeling is crucial for an adequate blood supply to the fetus with a failure to remodel implicated in the etiology of the hypertensive disorder preeclampsia. The mechanism by which trophoblasts induce this key process is unknown. This study gives the first insights into the potential mechanisms involved. Methods and Results— Spiral arteries were dissected from nonplacental bed biopsies obtained at Caesarean section, and a novel model was used to mimic in vivo events. Arteries were cultured with trophoblasts in the lumen, and apoptotic changes in the endothelial layer were detected after 20 hours, leading to loss of endothelium by 96 hours. In vitro, coculture experiments showed that trophoblasts stimulated apoptosis of primary decidual endothelial cells and an endothelial cell line. This was blocked by caspase inhibition and NOK2, a FasL blocking antibody. NOK2 also abrogated trophoblast-induced endothelial apoptosis in the vessel model. Conclusions— Extravillous trophoblast induction of endothelial apoptosis is a possible mechanism by which the endothelium is removed, and vascular remodeling may occur in uterine spiral arteries. Fas/FasL interactions have an important role in trophoblast-induced endothelial apoptosis

Examining the relationship between pubertal stage, adolescent health behaviours and stress

Background. This paper examines the associations between puberty and three important health behavlours (smoking, food intake and exercise) and explores whether these associations are mediated by puberty's relationship to stress and psychological difficulties.Method. Data were taken from the first year of the ongoing, 5-year, Health and Behaviours in Teenagers Study (HABITS). This is a school-based study set in 36 schools in London. In the first year of the study, 4320 students (2578 boys, 1742 girls) in their first year of secondary education took part.Results. Among girls, being more pubertally advanced was associated with a greater likelihood of having tried smoking. Among boys, being more pubertally advanced was associated with a greater likelihood of having tried smoking, a higher intake of high-fat food and higher levels of exercise. More pubertally advanced girls experienced more stress but not more psychological difficulties. There were no associations between puberty and either stress or psychological difficulties in boys. Stress and psychological difficulties were associated with health behaviours in girls and boys, but neither of these factors mediated the relationship between pubertal stage and health behaviours found in girls.Conclusions. These results suggest that the onset of puberty has a marked effect on the development of health behaviours. Puberty was related to an acceleration of the development of unhealthy behaviours, except for exercise behaviour in boys, where advanced puberty was associated with more exercise. These changes were unrelated to adolescent issues of stress and a causal explanation for these associations must be sought elsewhere

The pure rotation spectrum of ammonia

New experimental means for the study of absorption spectra in the extreme infra-red are described. These have been used in extending our knowledge of the pure rotation spectra to the case of a polyatomic molecule. The absorption spectrum of ammonia has been investigated in the region between 55μ and 130μ, and a very simple structure was found. Six lines were observed which belong to a pure rotation spectrum and are apparently due to changes in the energy of rotation of the ammonia molecule about an axis normal to the line of symmetry, that is, to transitions in which the quantum number j increases by unity. Other lines due to transitions with a change also of τ, the quantum number connected with rotations about the axis of symmetry, are absent. These facts are briefly discussed in connection with the predictions of the wave mechanics with which they are shown to be in accord. The moment of inertia of the ammonia molecule about an axis normal to the line of symmetry is estimated to be 2.77×10^(-40) gm cm^2

Does micro-credit empower women : evidence from Bangladesh

This paper examines the effects of men's and women's participation in group-based micro-credit programs on a large set of qualitative responses to questions that characterize women's autonomy and gender relations within the household. The data come from a special survey carried out in rural Bangladesh in 1998-99. The results are consistent with the view that women's participation in micro-credit programs helps to increase women's empowerment. Credit program participation leads to women taking a greater role in household decisionmaking, having greater access to financial and economic resources, having greater social networks, having greater bargaining power compared with their husbands, and having greater freedom of mobility. Female credit also tended to increase spousal communication in general about family planning and parenting concerns. The effects of male credit on women's empowerment were, at best, neutral, and at worse, decidedly negative. Male credit had a negative effect on several arenas of women's empowerment, including physical mobility, access to savings and economic resources, and power to manage some household transactions.Public Health Promotion,Economic Theory&Research,Health Monitoring&Evaluation,Anthropology,Environmental Economics&Policies,Health Monitoring&Evaluation,Anthropology,Environmental Economics&Policies,Housing&Human Habitats,Economic Theory&Research

The Philosophy of Simulation: Hot New Issues or Same Old Stew?

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Generation Rx Initiative

IMPACT. 1: Partnering with the Cardinal Health Foundation, the program has created educational resources aimed at specific populations that are available to the public for free. These toolkits provide presentations, handouts, activities, and other related materials. -- 2. The original community-based toolkit has been used in every state in the country. Additional toolkits have also been developed for youth, teens, college students, and seniors. A new elementary toolkit entitled "Medication Safety Patrol" debuted in the spring of 2014.OSU PARTNERS: College of Pharmacy; College of Social Work; Counseling and Consultation Services; OSU Extension; Office of Student WellnessCOMMUNITY PARTNERS: Cardinal Health Foundation; Drug Free Action Alliance; National Council on Patient Information and Education; Ohio Department of Health; Ohio Department of Alcohol and Drug Addiction Services; American Pharmacists Association - Academy of Student Pharmacists (APhA-ASP); The BACCHUS Network; InterACT; NOPE Task Force; Ohio Pharmacists Association; WOSU@COSI; Other colleges and universitiesPRIMARY CONTACT: Kenneth M. Hale ([email protected]); Nicole Cartwright Kwiek ([email protected])Unintentional drug poisoning is now the leading cause of accidental death in the country. On average, five people in Ohio and 100 across the U.S. die from these drug overdoses each day. The Generation Rx Initiative was created by the College of Pharmacy in 2007 to address this serious public health problem of prescription drug misuse and abuse