2,834 research outputs found

    Spending reflects not only who we are but also who we are around: The joint effects of individual and geographic personality on consumption

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    Interactionist theories are considered to have resolved the classic person-situation debate by demonstrating that human behavior is most accurately described as a function of both personal characteristics as well as environmental cues. According to these theories, personality traits form part of the personal characteristics that drive behavior. We suggest that psychological theory stands to gain from also considering personality traits as an important environmental characteristic that shapes sociocultural norms and institutions, and, in turn, behavior. Building on research in geographical psychology, we support this proposition by presenting evidence on the relationship of individual and regional personality with spending behavior. Analyzing the spending records of 111,336 participants (31,915,942 unique transactions) across 374 Local Authority Districts (LAD) in the United Kingdom, we first show that geographic regions with higher aggregate scores on a given personality trait collectively spend more money on categories associated with that trait. Shifting the focus to individual level spending as our behavioral outcome (N = 1,716), we further demonstrate that regional personality of a participant's home LAD predicts individual spending above and beyond individual personality. That is, a person's spending reflects both their own personality traits as well as the personality traits of the people around them. We use conditional random forest predictions to highlight the robustness of these findings in the presence of a comprehensive set of individual and regional control variables. Taken together, our findings empirically support the proposition that spending behaviors reflect personality traits as both personal and environmental characteristics. (PsycInfo Database Record (c) 2020 APA, all rights reserved)

    Prozessgeleitet Arbeiten in der Ernährungsberatung und -therapie - Anleitung und Übungen

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    Für das prozessgeleitete Arbeiten in der Ernährungsberatung und -therapie wurden von europäischen Hochschulen in Zusammenarbeit mit Berufsverbänden wissenschaftlich fundierte und unabhängige Empfehlungen erarbeitet. Mit der Frage, wie ihr Transfer in die Praxis gelingen kann, beschäftigte sich das „Modellprojekt für die diätetische Versorgung im Raum Fulda“ (MoDiVe) in seiner Laufzeit von 2018-2022 intensiv. Die gezielte, partizipativ angelegte Transferforschung lieferte tiefe Einblicke in Strukturen, Abläufe und Herausforderungen der Ernährungsberatung und -therapie. Begleitend wurden Feedbackschleifen mit Ernährungsfachkräften und Reflexionen im Diätetikforum Fulda, Fortbildungsveranstaltungen für Ernährungsfachkräfte in Osthessen, initiiert. Die daraus entstandenen Qualitätsstandards wurden nun in eine Praxisanleitung mit dem Titel „Prozessgeleitet Arbeiten in der Ernährungsberatung und -therapie – Anleitung und Übungen“ überführt. Die Praxisanleitung enthält differenzierte Ergebnisse der umfassenden Transferforschung, die die einzelnen Beratungsschritte transparent darstellen. Sie beginnt mit einer allgemeinen Übersicht zum prozessgeleiteten Arbeiten in der Diätetik. In den nachfolgenden Kapiteln werden das Diätetische Assessment, die Diätetische Diagnosestellung, die Planung und die Umsetzung der diätetischen Intervention und abschließend die Diätetische Outcome Evaluation behandelt. Vertieft wird die konkrete Umsetzung durch ein praktisches Fallbeispiel und Fragen, die zur Reflexion des eigenen beruflichen Handelns anregen

    Investigation of a Second Exhaust Valve Lift to Improve Combustion in a Methane - Diesel Dual-Fuel Engine

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    In recent years, the utilization of dual-fuel combustion has gained popularity in order to improve engine efficiency and emissions. With its high knock resistance, methane allows operation in high compression diesel engines with lower risk of knocking. With the use of diesel fuel as an ignition source, it is possible to exploit the advantages of lean combustion without facing problems to provide the high amount of ignition energy necessary to burn methane under such operating conditions. Another advantage is the variety of sources from which the primary fuel can be obtained. In addition to fossil sources, methane can also be produced from biomass or electrical energy. As the rate of substitution of diesel by methane increases, the trade- off between nitrogen oxide and soot is mitigated. However, emissions of carbon monoxide and unburned methane increase. Since carbon monoxide is toxic and methane has 25 times the global warming potential of carbon dioxide, these emission components pose a problem. Because of the stability of the molecule, methane catalysts require an exhaust gas temperature of over 500 °C in order to work effectively. In this work, the effect of conventional cooled external exhaust gas recirculation (EGR) and additional hot internal EGR are investigated for different substitution rates in a nonroad tractor engine converted to dual-fuel operation. The internal EGR rate is controlled by a variable second exhaust valve lift during the intake stroke – an approach which promises to benefit dual-fuel engines by increasing the in-cylinder gas temperature, thus favoring more complete combustion. A simulation model of the engine is used to determine the internal EGR rates and in-cylinder temperatures based on the experimental data. When internal EGR is used in combination with external EGR, the resulting emissions show additional reductions in nitrogen oxide (up to -51 %), carbon monoxide (up to -18 %) and methane (up to -28 %) with increasing internal EGR, while still maintaining low soot levels due to the substitution of diesel fuel for methane

    Nucleolar retention of a translational C/EBPα isoform stimulates rDNA transcription and cell size

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    The messenger RNA of the intronless CEBPA gene is translated into distinct protein isoforms through the usage of consecutive translation initiation sites. These translational isoforms have distinct functions in the regulation of differentiation and proliferation due to the presence of different N-terminal sequences. Here, we describe the function of an N-terminally extended protein isoform of CCAAT enhancer-binding protein α (C/EBPα) that is translated from an alternative non-AUG initiation codon. We show that a basic amino-acid motif within its N-terminus is required for nucleolar retention and for interaction with nucleophosmin (NPM). In the nucleoli, extended-C/EBPα occupies the ribosomal DNA (rDNA) promoter and associates with the Pol I-specific factors upstream-binding factor 1 (UBF-1) and SL1 to stimulate rRNA synthesis. Furthermore, during differentiation of HL-60 cells, endogenous expression of extended-C/EBPα is lost concomitantly with nucleolar C/EBPα immunostaining probably reflecting the reduced requirement for ribosome biogenesis in differentiated cells. Finally, overexpression of extended-C/EBPα induces an increase in cell size. Altogether, our results suggest that control of rRNA synthesis is a novel function of C/EBPα adding to its role as key regulator of cell growth and proliferation

    The statistical analysis of a clinical trial when a protocol amendment changed the inclusion criteria

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    Abstract Background Sometimes, protocol amendments that change the inclusion and exclusion criteria are required in clinical trials. Then, the patient populations before and after the amendment may differ. Methods We propose to perform separate statistical tests for the different phases, i.e. for the patients recruited before and after the amendment, and to combine the tests using Fisher's combination test. After a significant combination test a multiple testing procedure can be applied to identify the phase(s) to which a proof of efficacy refers. We assume that the amendment(s) are not based on any type of unblinded data. The proposed method is investigated within a simulation study. Results The proposed combination approach is superior to the 'naïve' strategy to ignore the differences between the phases and pooling the data to perform just one statistical test. This superiority disappears when there are hardly any differences between the two phases. Conclusion When one or more protocol amendments change the inclusion and exclusion criteria, one should realize that the populations may differ. In this case, separate tests for the different phases together with a combination test are a powerful method that can be applied in a variety of settings. The (first) amendment should specify the combination test to be applied in order to combine the different phases.</p

    Boosting Long-term Memory via Wakeful Rest: Intentional Rehearsal is not Necessary, Automatic Consolidation is Sufficient.

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    <div><p>People perform better on tests of delayed free recall if learning is followed immediately by a short wakeful rest than by a short period of sensory stimulation. Animal and human work suggests that wakeful resting provides optimal conditions for the consolidation of recently acquired memories. However, an alternative account cannot be ruled out, namely that wakeful resting provides optimal conditions for intentional rehearsal of recently acquired memories, thus driving superior memory. Here we utilised non-recallable words to examine whether wakeful rest boosts long-term memory, even when new memories could not be rehearsed intentionally during the wakeful rest delay. The probing of non-recallable words requires a recognition paradigm. Therefore, we first established, via Experiment 1, that the rest-induced boost in memory observed via free recall can be replicated in a recognition paradigm, using concrete nouns. In Experiment 2, participants heard 30 non-recallable non-words, presented as ‘foreign names in a bridge club abroad’ and then either rested wakefully or played a visual spot-the-difference game for 10 minutes. Retention was probed via recognition at two time points, 15 minutes and 7 days after presentation. As in Experiment 1, wakeful rest boosted recognition significantly, and this boost was maintained for at least 7 days. Our results indicate that the enhancement of memory via wakeful rest is <i>not</i> dependent upon intentional rehearsal of learned material during the rest period. We thus conclude that consolidation is <i>sufficient</i> for this rest-induced memory boost to emerge. We propose that wakeful resting allows for superior memory consolidation, resulting in stronger and/or more veridical representations of experienced events which can be detected via tests of free recall and recognition.</p></div

    Fat Mass and Obesity-Associated Gene (FTO) in Eating Disorders: Evidence for Association of the rs9939609 Obesity Risk Allele with Bulimia nervosa and Anorexia nervosa

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    Objective: The common single nucleotide polymorphism (SNP) rs9939609 in the fat mass and obesity-associated gene (FTO) is associated with obesity. As genetic variants associated with weight regulation might also be implicated in the etiology of eating disorders, we evaluated whether SNP rs9939609 is associated with bulimia nervosa (BN) and anorexia nervosa (AN). Methods: Association of rs9939609 with BN and AN was assessed in 689 patients with AN, 477 patients with BN, 984 healthy non-population-based controls, and 3,951 population-based controls (KORA-S4). Based on the familial and premorbid occurrence of obesity in patients with BN, we hypothesized an association of the obesity risk A-allele with BN. Results: In accordance with our hypothesis, we observed evidence for association of the rs9939609 A-allele with BN when compared to the non-population-based controls (unadjusted odds ratio (OR) = 1.142, one-sided 95% confidence interval (CI) 1.001-infinity; one-sided p = 0.049) and a trend in the population-based controls (OR = 1.124, one-sided 95% CI 0.932-infinity; one-sided p = 0.056). Interestingly, compared to both control groups, we further detected a nominal association of the rs9939609 A-allele to AN (OR = 1.181, 95% CI 1.027-1.359, two-sided p = 0.020 or OR = 1.673, 95% CI 1.101-2.541, two-sided p = 0.015,). Conclusion: Our data suggest that the obesity-predisposing FTO allele might be relevant in both AN and BN. Copyright (C) 2012 S. Karger GmbH, Freibur

    Female Burying Beetles Benefit from Male Desertion: Sexual Conflict and Counter-Adaptation over Parental Investment

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    Sexual conflict drives the coevolution of sexually antagonistic traits, such that an adaptation in one sex selects an opposing coevolutionary response from the other. Although many adaptations and counteradaptations have been identified in sexual conflict over mating interactions, few are known for sexual conflict over parental investment. Here we investigate a possible coevolutionary sequence triggered by mate desertion in the burying beetle Nicrophorus vespilloides, where males commonly leave before their offspring reach independence. Rather than suffer fitness costs as a consequence, our data suggest that females rely on the male's absence to recoup some of the costs of larval care, presumably because they are then free to feed themselves on the carcass employed for breeding. Consequently, forcing males to stay until the larvae disperse reduces components of female fitness to a greater extent than caring for young singlehandedly. Therefore we suggest that females may have co-evolved to anticipate desertion by their partners so that they now benefit from the male's absence
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