111 research outputs found

    New library buildings: the Houston Academy of Medicine--Texas Medical Center Library.

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    A historical account is given of the Houston Academy of Medicine--Texas Medical Center Library within its Texas Medical Center setting in Houston, Texas. Outlined are planning, financing, and construction of the new library, which consists in part of new building and in part of renovated interiors of an old building originally completed in 1954. A concise picture is given of the new library\u27s interiors, showing its functional success for users and employees alike. An architectural summary is appended showing gross and net footages, source of funds, costs and capacities

    Alterations in neuromuscular function in girls with generalized joint hypermobility

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    BACKGROUND: Generalized Joint Hypermobility (GJH) is associated with increased risk of musculoskeletal joint pain. We investigated neuromuscular performance and muscle activation strategy. METHODS: Girls with GJH and non-GJH (NGJH) performed isometric knee flexions (90°,110°,130°), and extensions (90°) at 20 % Maximum Voluntary Contraction, and explosive isometric knee flexions while sitting. EMG was recorded from knee flexor and extensor muscles. RESULTS: Early rate of torque development was 53 % faster for GJH. Reduced hamstring muscle activation in girls with GJH was found while knee extensor and calf muscle activation did not differ between groups. Flexion-extension and medial-lateral co-activation ratio during flexions were higher for girls with GJH than NGJH girls. CONCLUSIONS: Girls with GJH had higher capacity to rapidly generate force than NGJH girls which may reflect motor adaptation to compensate for hypermobility. Higher medial muscle activation indicated higher levels of medial knee joint compression in girls with GJH. Increased flexion-extension co-activation ratios in GJH were explained by decreased agonist drive to the hamstrings

    Captura de carbono mediante estimación de biomasa aérea y necromasa en la zona de aguajales del alto mayo, Sector Tingana Moyobamba-San Martin 2017

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    El trabajo de investigación tiene como objetivo principal la estimación de carbono mediante la biomasa aérea y necromasa de la Zona De Aguajales Del Alto Mayo, Sector Tingana Moyobamba-San Martin. Para determinar el objetivo se indentificaron la condición de bosque donde ambudan la Mauritia Flexuosa dentro de ese ecosistema el grado de intervención es baja la cual nos indica que las especies e individuos que se encuentran están en su hábitat normal. Para estimar la biomasa aérea dentro del ecosistema de aguajales se considero el dap ≥7.5 las cuales fueron marcadas y identificadas por especie y familia ademas se considero 9 muestras de necromasa en hojarasca las cales fueron llevadas al laboratorio para su respectiva evaluación. Para determinar la cantidad de carbono almacenado en biomasa se utilizo ecuaciones alometricas no destructivas se considero todas la familia y especies con dap ≥7.5 las cuales nos arrojaron 872 especies en ecosistes de aguajales las cuales nos arrojo una cantidad de 82.7293938 MgCha de carbono además para determinar la necromasa de hojarasca se recolecto 9 muestras las cuales nos arrojaron 1.29 MgCha. Notándose de manera clara que la biomasa aérea es la que tiene mayor captura de carbono la cual se debe dar una importancia de cosnservacion para asi mitigar el cambio climático

    Captura de carbono mediante estimación de biomasa aérea y necromasa en la zona de aguajales del alto mayo, Sector Tingana Moyobamba-San Martin 2017

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    El trabajo de investigación tiene como objetivo principal la estimación de carbono mediante la biomasa aérea y necromasa de la Zona De Aguajales Del Alto Mayo, Sector Tingana Moyobamba-San Martin. Para determinar el objetivo se indentificaron la condición de bosque donde ambudan la Mauritia Flexuosa dentro de ese ecosistema el grado de intervención es baja la cual nos indica que las especies e individuos que se encuentran están en su hábitat normal. Para estimar la biomasa aérea dentro del ecosistema de aguajales se considero el dap ≥7.5 las cuales fueron marcadas y identificadas por especie y familia ademas se considero 9 muestras de necromasa en hojarasca las cales fueron llevadas al laboratorio para su respectiva evaluación. Para determinar la cantidad de carbono almacenado en biomasa se utilizo ecuaciones alometricas no destructivas se considero todas la familia y especies con dap ≥7.5 las cuales nos arrojaron 872 especies en ecosistes de aguajales las cuales nos arrojo una cantidad de 82.7293938 MgCha de carbono además para determinar la necromasa de hojarasca se recolecto 9 muestras las cuales nos arrojaron 1.29 MgCha. Notándose de manera clara que la biomasa aérea es la que tiene mayor captura de carbono la cual se debe dar una importancia de cosnservacion para asi mitigar el cambio climático

    Monitoring guidance for patients with hypophosphatasia treated with asfotase alfa.

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    Hypophosphatasia (HPP) is a rare, inherited, systemic, metabolic disorder caused by autosomal recessive mutations or a single dominant-negative mutation in the gene encoding tissue-nonspecific alkaline phosphatase (TNSALP). The disease is associated with a broad range of signs, symptoms, and complications, including impaired skeletal mineralization, altered calcium and phosphate metabolism, recurrent fractures, pain, respiratory problems, impaired growth and mobility, premature tooth loss, developmental delay, and seizures. Asfotase alfa is a human, recombinant enzyme replacement therapy that is approved in many countries for the treatment of patients with HPP. To address the unmet need for guidance in the monitoring of patients receiving asfotase alfa, an international panel of physicians with experience in diagnosing and managing HPP convened in May 2016 to discuss treatment monitoring parameters. The panel discussions focused on recommendations for assessing and monitoring patients after the decision to treat with asfotase alfa had been made and did not include recommendations for whom to treat. Based on the consensus of panel members, this review provides guidance on the monitoring of patients with HPP during treatment with asfotase alfa, including recommendations for laboratory, efficacy, and safety assessments and the frequency with which these should be performed during the course of treatment. Recommended assessments are based on patient age and include regular monitoring of biochemistry, skeletal radiographs, respiratory function, growth, pain, mobility and motor function, and quality of life. Because of the systemic presentation of HPP, a coordinated, multidisciplinary, team-based, patient-focused approach is recommended in the management of patients receiving asfotase alfa. Monitoring of efficacy and safety outcomes must be tailored to the individual patient, depending on medical history, clinical manifestations, availability of resources in the clinical setting, and the clinician's professional judgment

    The Emergence of Extended Field Technology in the Air Force

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    The wide-field eddy-current probe was developed to fulfill the inspection requirement of the broach slots in Pratt & Whitney F100-PW-220 Stage-1 and Stage-3 Compressor Disks. The flaw-detection requirement is to inspect an area 0.07 in. from the inner radius of the slot and 0.10 in. from the top and bottom edges for determining the presence of 0.006-and 0.010-in.-deep axially oriented flaws (Figure 1). While the slot is relatively small, the time required for inspection using the previous method is considerable. With this method a D20 (0.029-in.-diameter) split “D” coil is scanned in a “sew-stitch” fashion in the axial direction of the slot. After each scan the probe is indexed one quarter of the coil diameter. A total of 88 scans per slot is required for complete coverage, the time per slot being 20 min; with 40 slots the total inspection time per part is 14 hr when gain-calibration time is taken into account.</p
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