Experiências formativas com o projeto de extensão ritmos populares do Brasil

The present study aimed to share the formative experiences in Physical Education experienced by a scholarship holder of the Popular Ritmos do Brasil extension project, during the years 2019 and 2020. For this purpose, a qualitative, descriptive study was carried out, which was adopted the autobiographical narrative as a methodological assumption, where the exercise of ‘‘talking about oneself’’ constituted an important resource for teacher education. Data were produced from different sources, such as personal narratives about lived experiences, iconographic images and records of materials produced related to pedagogical practice. in the extension project. Among the experiences considered significant for training experienced in the two years of interventions in the project, the initial exercise of teaching stands out; the challenges and possibilities for the continuity of the project in times of pandemic and the contributions of the university extension to the initial training of teachers.O presente estudo teve como objetivo compartilhar as experiências formativas em Educação Física vivenciadas por um bolsista do projeto de extensão Ritmos Populares do Brasil, durante os anos de 2019 e 2020. Para tanto, realizou-se um estudo de natureza qualitativa, descritiva, que adotou a narrativa autobiográfica como pressuposto metodológico, onde o exercício de ‘falar de si’ se constituiu como importante recurso para a formação docente. Os dados foram produzidos por meio de diferentes fontes, como narrativas pessoais sobre as experiências vivenciadas, imagens iconográficas e registros de materiais produzidos relativos à prática pedagógica. Além desses instrumentos, aplicou-se um questionário a 16 participantes do projeto de extensão. Dentre as experiências consideradas significativas para a formação vivenciadas nos dois anos de intervenções no projeto, destaca-se o exercício inicial da docência; os desafios e as possibilidades para a continuidade do projeto em tempos de pandemia e as contribuições da extensão universitária para a formação inicial de professores

Experiências Formativas com o Projeto de Extensão Ritmos Populares do Brasil

The present study aimed to share the formative experiences in Physical Education experienced by a scholarship holder of the Popular Ritmos do Brasil extension project, during the years 2019 and 2020. For this purpose, a qualitative, descriptive study was carried out, which was adopted the autobiographical narrative as a methodological assumption, where the exercise of ‘‘talking about oneself’’ constituted an important resource for teacher education. Data were produced from different sources, such as personal narratives about lived experiences, iconographic images and records of materials produced related to pedagogical practice. in the extension project. Among the experiences considered significant for training experienced in the two years of interventions in the project, the initial exercise of teaching stands out; the challenges and possibilities for the continuity of the project in times of pandemic and the contributions of the university extension to the initial training of teachers.O presente estudo teve como objetivo compartilhar as experiências formativas em Educação Física vivenciadas por um bolsista do projeto de extensão Ritmos Populares do Brasil, durante os anos de 2019 e 2020. Para tanto, realizou-se um estudo de natureza qualitativa, descritiva, que adotou a narrativa autobiográfica como pressuposto metodológico, onde o exercício de ‘falar de si’ se constituiu como importante recurso para a formação docente. Os dados foram produzidos por meio de diferentes fontes, como narrativas pessoais sobre as experiências vivenciadas, imagens iconográficas e registros de materiais produzidos relativos à prática pedagógica. Além desses instrumentos, aplicou-se um questionário a 16 participantes do projeto de extensão. Dentre as experiências consideradas significativas para a formação vivenciadas nos dois anos de intervenções no projeto, destaca-se o exercício inicial da docência; os desafios e as possibilidades para a continuidade do projeto em tempos de pandemia e as contribuições da extensão universitária para a formação inicial de professores

All-ceramic and porcelain-fused-to-metal fixed partial dentures: a comparative study by 2D finite element analyses

All-ceramic fixed partial dentures (FPDs) have an esthetic approach for oral rehabilitation. However, metal-ceramic FPDs are best indicated in the posterior area where the follow-up studies found a lower failure rate. This 2D finite element study compared the stress distribution on 3-unit all-ceramic and metal-ceramic FPDs and identified the areas of major risk of failure. Three FPD models were designed: (1) metal-ceramic FPD; (2) All-ceramic FPD with the veneering porcelain on the occlusal and cervical surface of the abutment tooth; (3) All-ceramic FPD with the veneering porcelain only on the occlusal surface. A 100 N load was applied in an area of 0.5 mm² on the working cusps, following these simulations: (1) on the abutment teeth and the pontic; (2) only on the abutment teeth; and (3) only on the pontic. Relative to the maximum stress values found for the physiological load, all-ceramic FPD with only occlusal veneering porcelain produced the lowest stress value (220 MPa), followed by all-ceramic FPD with cervical veneering porcelain (322 MPa) and metal-ceramic FPD (387 MPa). The stress distribution of the load applied on the abutments was significantly better compared to the other two load simulations. The highest principal stress values were low and limited in a small area for the three types of models under this load. When the load was applied on the pontic, the highest stress values appeared on the connector areas between the abutments and pontic. In conclusion, the best stress values and distribution were found for the all-ceramic FPD with the veneering porcelain only on the occlusal surface. However, in under clinical conditions, fatigue conditions and restoration defects must be considered

CONSERVATION UNITS IN AMAZONAS: A brief reflection related to the Anavilhanas National Park

Given the importance of strengthening  reflections on Conservation Units (UC's) in the Amazon, the present study proposes a discussion on the Parks of the state of Amazonas, as well as a brief reflection related to the Anavilhanas National Park. In the first moment, the number of parks and their spheres of national, state and municipal management is presented. Then, the considerations are turned to the Anavilhanas National Park and its peculiarities. The methodology used consists of a bibliographic review around this theme, as well as the use of information from the Institutions that work directly in the area. As a result, the natural supply of parks represents a potential ally in terms of preserving resources and developing sustainable ecotourism activities. Anavilhanas Park is a national conservation unit, known worldwide, which presents the necessary attractions for sustainable ecotourism, since, since its recognition, as a protected area, it has been generating positive results for this follow-up.

Análise de hastes delgadas em grelhas hiperestáticas de tabuleiro de pontes / Analysis of thin rods in hyperstatic bridge tray grids

Este artigo tem por objetivo determinar as tensões devido ao momento de flexão e de bimomento em grelhas hiperestáticas utilizando hastes delgadas compostas por perfis abertos. A análise foi feita utilizando-se o Método da Flexibilidade e determinaram-se as tensões nos flanges dos perfis por meio de gráficos que foram obtidos variando-se as dimensões geométricas dos perfis soldados. Para a análise foram utilizados perfis VS 200x19, VS 300x38, VS 400x44, VS 500x97, VS 600x152, VS 700x 166, VS 800x160, VS 900x191 e VS 1000x217. A grelha possui um espaço entre vigas L = 3m e um carregamento perpendicular atuante de p = 1 kN/m². Nove pontos foram analisados nas interseções entre as vigas longitudinais e transversais. Constatou-se que magnitude da tensão devida ao bimomento representa mais de 15,3% da magnitude da tensão devido ao momento de flexão quando considerada a mesma seção.

Superficial technique for tear trough filling with cohesive polydensified matrix hyaluronic acid

Introduction: Deep tear troughs create unaesthetic hollows that often worsen the color alteration and aspect of dark undereye circles, thus giving an aged and tired appearance to the eyes, even in younger individuals. The use of dermal fillers for the restoration of volume loss in the area, with a wide variety of products and techniques, has been the most suitable treatment. Aim: Description and evaluation of the superficial intradermal injection technique for tear trough filling using cohesive polydensified matrix hyaluronic acid. Materials and Methods: 120 patients from Faculdade de Medicina do ABC’s Cosmetic Dermatology Sector and a private practice treated between the years 2011 and 2016. Results: All the patients rated the treatment result as good or very good. No important or long-lasting adverse effects were reported; the Tyndall effect was not observed either. Conclusion: The superficial technique is an easy and safe method to treat the tear trough deformity, with high rates of good aesthetic results. DOI: http://dx.doi.org/10.5281/zenodo.427243

The influence of the loading mode on the stress distribution on the connector region of metal-ceramic and all-ceramic fixed partial denture.

Studies pertaining to the mechanical behavior of fixed partial dentures (FPDs) frequently found the highest tensile stress values at the connector region when load is applied at the pontic central region. The connector region is considered the weakest point of the prosthesis with the greatest potential of fractures, regardless of the material used. This 2D finite element study compared the stress distribution on three‐element all‐ceramic and metal‐ceramic FPDs with different loading conditions. Three FPD models were designed: (i) metal‐ceramic FPD; (ii) all‐ceramic FPD with the veneering porcelain only on the occlusal face; and (iii) all‐ceramic FPD with the veneering porcelain on the occlusal and cervical face of the pontic. Loads of 100 N were applied following these simulations: (i) distributed on all working cusps; (ii) only on the abutment teeth; and (iii) only on the pontic. There is a significant change on the stress distribution and on the tensile stress values when the load configuration is changed. The stress distribution from the load applied on the abutments was significantly better compared with the other two load simulations. When the loads were applied on the pontic and distributed on all working cusps, the highest tensile stress values appeared on the cervical region of the connectors between the abutments and the pontic. However, when the load was applied on the abutment teeth, the maximum tensile stress value significantly decreased and was located on the occlusal region of the connectors. In fact, the load applied on the pontic region does not simulate the clinical situation. Studies using this load configuration have overestimated the connector regions as having the highest probability of failures.Indisponível

Aspectos epidemiológicos nas leptospiroses: Pesquisa de anticorpos anti-Leptospira spp, isolamento e pesquisa biomolecular em bovinos, roedores e trabalhadores de propriedades rurais do Município de Botucatu, SP, Brasil

A leptospirose é uma infecção amplamente difundida pelo mundo, transmitida entre o homem e os animais que causa uma queda na produção de rebanhos bovinos, e oferece riscos relacionados à saúde pública sendo uma importante zoonose. Foram estudadas 27 propriedades de pecuária bovina leiteira em Botucatu-SP e limítrofes, com colheitas de amostras de sangue e rim de roedores, sangue e urina de bovinos e sangue dos trabalhadores. A sorologia foi realizada pela soroaglutinação microscópica (SAM). Foi tentado o isolamento de leptospiras por cultura da urina dos bovinos e dos rins dos roedores. Foi realizada a reação em cadeia pela polimerase (PCR) dos rins dos roedores. Para a SAM, 46/140 (32,85%) amostras de soro bovino e 8/34 (23,53%) humana foram positivas, respectivamente. Para as amostras humanas, o sorovar Bratislava (37,51%) apresentou maior ocorrência, enquanto que para os bovinos, os sorovares mais freqüentes foram Hardjo e Castellonis, com 26,08% cada. Todos os roedores foram negativos à sorologia. Nenhuma leptospira foi isolada, e as amostras de rim foram negativas à PCR. Nos bovinos, a água de açudes e as ordenhadas com má qualidade de higiene foram consideradas importantes riscos de infecção nas propriedades acometidas (p<0,05), onde outros problemas reprodutivos, exceto aborto, podem estar relacionados. Por outro lado, para o homem o sistema de drenagem foi o mais importante fator de risco nas propriedades estudadas. Assim, enfatiza-se a necessidade de melhora no manejo zoosanitário das propriedades, principalmente com relação ao suprimento de água.Leptospirosis is a worldwide infection, transmitted between man and animals that causes a decrease in the production of bovine flocks, and offer risks for public health, as an important zoonosis. The rodents are the main reservoirs of leptospires. It was studied 27 dairy farm properties located in or near from Botucatu-SP, Brazil. In these farms were collected blood and kidney samples from rodents, blood and urine samples from bovines and blood samples from the workers. The serology was performed with microscopic agglutination test (MAT). Samples of bovine urine and rodent kidneys were cultivated searching for leptospires isolation. The polymerase chain reaction (PCR) of the kidneys of the rodents was performed. In MAT, 46/140 (32.85%) bovine and 8/34 (23.53%) human sera samples were positive, respectively. In human samples, the serovar Brastilava (37.51%) presented the highest occurrence, while in bovines, the serovars Hardjo and Castellonis were most frequent, with 26.08% each one. All of the rodents were negatives in serology. No leptospire was isolated, and kidney samples were negative in PCR. In bovines, the dam water and the bad hygiene quality of milking process were considered important risks of infection in the affected properties (p<0.05), where other reproductive problems, except abortion, can be related. In other side, to human beings the drainage system was the most important risk factor in the studied properties. Thus, it was verified the necessity of an improvement in zoosanitary handling of the properties, mainly of water supply

Treatment of facial aging with calcium hydroxyapatite - filling and lifting concept

The face is organized in five different layers (skin, muscles, supportive ligaments, fat pads and bones), which are continuous and interconnected with each other from the scalp to the neck. As a result of aging, changes occur in all its tissues and structures, triggering a cascade of effects in the adjacent areas. Actually, the more it is known about the loss of volume, the better it is to establish the target spots for volume replacement, with consequent more natural- and harmonious-looking outcomes. However, the skin is the outer envelope of the face, which, in the natural process of aging, has a lower capacity to completely accommodate any underlying volume loss or displacement. The result is the formation of creases and folds due to skin sagging. To describe the effects of the injection of calcium hydroxyapatite (CaHA) targeting two objectives at the same time: the restoration of volume loss to compensate the changes in the tridimensional structure and the improvement in skin texture caused by the stimulus to collagen synthesis, thus reducing the sagging of soft tissues envelope. Owing to the mechanism of action of CaHA, its application can be done in two differentiated and little invasive ways so that these objectives can be reached simultaneously. This technique can provide safe, natural and long-lasting rejuvenating effects. DOI: http://dx.doi.org/10.5281/zenodo.356983

Panorama dos nutlins como protótipo para terapia do câncer

A p53 é uma proteína supressora tumoral que desempenha papel crucial nadefesa da célula contra mutações deletérias e transformações cancerosas. Ela é ativada por meio da ação de agentes genotóxicos (irradiação ultravioleta, estresse oxidativo, drogas citotóxicas) ou mesmo não genotóxicos (hipóxia, hipertermia, depleção de ribonucleotídeos). Uma vez ativada, a p53 coordena o sistema de reparo da célula levando-a à parada do ciclo celular, à senescência ou à apoptose. A via de sinalização da proteína p53 encontra-se inativada em todos os tipos de câncer e este fato tem chamado a atenção de muitos pesquisadores no sentido do desenvolvimento de novas terapias farmacológicas baseadas no reestabelecimento dessa via. Os níveis de p53 na célula estão sob o rígido controle do regulador negativo MDM2 via ubiquitinação. A p53 também controla a transcrição do MDM2 gerando uma regulação por feedback em que as duas proteínas mutuamente controlam seus níveis celulares. Dessa forma, foi pensado que o bloqueio da interação p53-MDM2 poderia levar ao efeito farmacológico antitumoral e várias moléculas inibidoras foram testadas para este fim, dentre elas uma família de imidazolinas tetrassubstituídas, chamadas nutlins. Estes compostos podem ativar seletivamente a via de sinalização da p53 in vitro e in vivo em linhagens de tumores humanos que apresentam alta expressão de HDM2 (o tipo humano de MDM2) levando à inibição do crescimento celular e à apoptose. Os inibidores de MDM2 representam uma classe promissora de ativadores da p53 que podem se tornar fármacos efetivos no tratamento do câncer e também no diagnóstico por imagem