739 research outputs found

    The Eminent Doctor Fizz : Dr. Fizz and Chorus

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    https://digitalcommons.library.umaine.edu/mmb-vp/4599/thumbnail.jp

    Room temperature magnetism in LaVO3/SrVO3 superlattices by geometrically confined doping

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    Based on the Hubbard model of strongly correlated systems, a reduction in the bandwidth of the electrons can yield a substantial change in the properties of the material. One method to modify the bandwidth is geometrically confined doping, i.e. the introduction of a (thin) dopant layer in a material. In this paper, the magnetic properties of LaVO3_3/SrVO3_3 superlattices, in which the geometrically confined doping is produced by a one monolayer thick SrVO3_3 film, are presented. In contrast to the solid solution La1x_{1-x}Srx_xVO3_3, such superlattices have a finite magnetization up to room temperature. Furthermore, the total magnetization of the superlattice depends on the thickness of the LaVO3_3 layer, indicating an indirect coupling of the magnetization that emerges at adjacent dopant layers. Our results show that geometrically confined doping, like it can be achieved in superlattices, reveals a way to induce otherwise unaccessible phases, possibly even with a large temperature scale.Comment: 5 pages, 4 figure

    T and CPT Symmetries in Entangled Neutral Meson Systems

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    Genuine tests of an asymmetry under T and/or CPT transformations imply the interchange between in-states and out-states. I explain a methodology to perform model-indepedent separate measurements of the three CP, T and CPT symmetry violations for transitions involving the decay of the neutral meson systems in B- and {\Phi}-factories. It makes use of the quantum-mechanical entanglement only, for which the individual state of each neutral meson is not defined before the decay of its orthogonal partner. The final proof of the independence of the three asymmetries is that no other theoretical ingredient is involved and that the event sample corresponding to each case is different from the other two. The experimental analysis for the measurements of these three asymmetries as function of the time interval {\Delta}t > 0 between the first and second decays is discussed, as well as the significance of the expected results. In particular, one may advance a first observation of true, direct, evidence of Time-Reserval-Violation in B-factories by many standard deviations from zero, without any reference to, and independent of, CP-Violation. In some quantum gravity framework the CPT-transformation is ill-defined, so there is a resulting loss of particle-antiparticle identity. This mechanism induces a breaking of the EPR correlation in the entanglement imposed by Bose statistics to the neutral meson system, the so-called {\omega}-effect. I present results and prospects for the {\omega}-parameter in the correlated neutral meson-antimeson states.Comment: Proc. DISCRETE 2010, Symposium on Prospects in the Physics of Discrete Symmetries, December 2010, Rom

    The Unique Brain Anatomy of Meditation Practitioners: Alterations in Cortical Gyrification

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    Several cortical regions are reported to vary in meditation practitioners. However, prior analyses have focused primarily on examining gray matter or cortical thickness. Thus, additional effects with respect to other cortical features might have remained undetected. Gyrification (the pattern and degree of cortical folding) is an important cerebral characteristic related to the geometry of the brain’s surface. Thus, exploring cortical gyrification in long-term meditators may provide additional clues with respect to the underlying anatomical correlates of meditation. This study examined cortical gyrification in a large sample (n = 100) of meditators and controls, carefully matched for sex and age. Cortical gyrification was established by calculating mean curvature across thousands of vertices on individual cortical surface models. Pronounced group differences indicating larger gyrification in meditators were evident within the left precentral gyrus, right fusiform gyrus, right cuneus, as well as left and right anterior dorsal insula (the latter representing the global significance maximum). Positive correlations between gyrification and the number of meditation years were similarly pronounced in the right anterior dorsal insula. Although the exact functional implications of larger cortical gyrification remain to be established, these findings suggest the insula to be a key structure involved in aspects of meditation. For example, variations in insular complexity could affect the regulation of well-known distractions in the process of meditation, such as daydreaming, mind-wandering, and projections into past or future. Moreover, given that meditators are masters in introspection, awareness, and emotional control, increased insular gyrification may reflect an integration of autonomic, affective, and cognitive processes. Due to the cross-sectional nature of this study, further research is necessary to determine the relative contribution of nature and nurture to links between cortical gyrification and meditation

    Quantum Fields on the Groenewold-Moyal Plane: C, P, T and CPT

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    We show that despite the inherent non-locality of quantum field theories on the Groenewold-Moyal (GM) plane, one can find a class of C{\bf C}, P{\bf P}, T{\bf T} and CPT{\bf CPT} invariant theories. In particular, these are theories without gauge fields or with just gauge fields and no matter fields. We also show that in the presence of gauge fields, one can have a field theory where the Hamiltonian is C{\bf C} and T{\bf T} invariant while the SS-matrix violates P{\bf P} and CPT{\bf CPT}. In non-abelian gauge theories with matter fields such as the electro-weak and QCDQCD sectors of the standard model of particle physics, C{\bf C}, P{\bf P}, T{\bf T} and the product of any pair of them are broken while CPT{\bf CPT} remains intact for the case θ0i=0\theta^{0i} =0. (Here xμxνxνxμ=iθμνx^{\mu} \star x^{\nu} - x^{\nu} \star x^{\mu} = i \theta^{\mu \nu}, xμx^{\mu}: coordinate functions, θμν=θνμ=\theta^{\mu \nu} = -\theta^{\nu \mu}= constant.) When θ0i0\theta^{0i} \neq 0, it contributes to breaking also P{\bf P} and CPT{\bf CPT}. It is known that the SS-matrix in a non-abelian theory depends on θμν\theta^{\mu \nu} only through θ0i\theta^{0i}. The SS-matrix is frame dependent. It breaks (the identity component of the) Lorentz group. All the noncommutative effects vanish if the scattering takes place in the center-of-mass frame, or any frame where θ0iPiin=0\theta^{0i}P^{\textrm{in}}_{i} = 0, but not otherwise. P{\bf P} and CPT{\bf CPT} are good symmetries of the theory in this special case.Comment: 18 pages, 1 figure, revised, 2 references adde

    Quantum Fields on the Groenewold-Moyal Plane

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    We give an introductory review of quantum physics on the noncommutative spacetime called the Groenewold-Moyal plane. Basic ideas like star products, twisted statistics, second quantized fields and discrete symmetries are discussed. We also outline some of the recent developments in these fields and mention where one can search for experimental signals.Comment: 50 pages, 3 figures. v2: published versio

    Thermodynamics of the superconducting state in Calcium at 200 GPa

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    The thermodynamic parameters of the superconducting state in Calcium under the pressure at 200 GPa were calculated. The Coulomb pseudopotential values (μ\mu^{\star}) from 0.1 to 0.3 were taken into consideration. It has been shown, that the specific heat's jump at the critical temperature and the thermodynamic critical field near zero Kelvin strongly decrease with μ\mu^{\star}. The dimensionless ratios r1ΔC(TC)/CN(TC)r_{1}\equiv \Delta C(T_{C})/C^{N}(T_{C}) and r2TCCN(TC)/HC2(0)r_{2}\equiv T_{C}C^{N}(T_{C})/H^{2}_{C}(0) significantly differ from the predictions based on the BCS model. In particular, r1r_{1} decreases from 2.64 to 1.97 with the Coulomb pseudopotential; whereas r2r_{2} increases from 0.140 to 0.157. The numerical results have been supplemented by the analytical approach.Comment: 7 pages, 6 figure

    Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum

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    The plant cytotoxin ricin enters target mammalian cells by receptor-mediated endocytosis and undergoes retrograde transport to the endoplasmic reticulum (ER). Here, its catalytic A chain (RTA) is reductively separated from the cell-binding B chain, and free RTA enters the cytosol where it inactivates ribosomes. Cytosolic entry requires unfolding of RTA and dislocation across the ER membrane such that it arrives in the cytosol in a vulnerable, nonnative conformation. Clearly, for such a dislocated toxin to become active, it must avoid degradation and fold to a catalytic conformation. Here, we show that, in vitro, Hsc70 prevents aggregation of heat-treated RTA, and that RTA catalytic activity is recovered after chaperone treatment. A combination of pharmacological inhibition and cochaperone expression reveals that, in vivo, cytosolic RTA is scrutinized sequentially by the Hsc70 and Hsp90 cytosolic chaperone machineries, and that its eventual fate is determined by the balance of activities of cochaperones that regulate Hsc70 and Hsp90 functions. Cytotoxic activity follows Hsc70-mediated escape of RTA from an otherwise destructive pathway facilitated by Hsp90. We demonstrate a role for cytosolic chaperones, proteins typically associated with folding nascent proteins, assembling multimolecular protein complexes and degrading cytosolic and stalled, cotranslocational clients, in a toxin triage, in which both toxin folding and degradation are initiated from chaperone-bound states

    Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum

    Get PDF
    The plant cytotoxin ricin enters target mammalian cells by receptor-mediated endocytosis and undergoes retrograde transport to the endoplasmic reticulum (ER). Here, its catalytic A chain (RTA) is reductively separated from the cell-binding B chain, and free RTA enters the cytosol where it inactivates ribosomes. Cytosolic entry requires unfolding of RTA and dislocation across the ER membrane such that it arrives in the cytosol in a vulnerable, nonnative conformation. Clearly, for such a dislocated toxin to become active, it must avoid degradation and fold to a catalytic conformation. Here, we show that, in vitro, Hsc70 prevents aggregation of heat-treated RTA, and that RTA catalytic activity is recovered after chaperone treatment. A combination of pharmacological inhibition and cochaperone expression reveals that, in vivo, cytosolic RTA is scrutinized sequentially by the Hsc70 and Hsp90 cytosolic chaperone machineries, and that its eventual fate is determined by the balance of activities of cochaperones that regulate Hsc70 and Hsp90 functions. Cytotoxic activity follows Hsc70-mediated escape of RTA from an otherwise destructive pathway facilitated by Hsp90. We demonstrate a role for cytosolic chaperones, proteins typically associated with folding nascent proteins, assembling multimolecular protein complexes and degrading cytosolic and stalled, cotranslocational clients, in a toxin triage, in which both toxin folding and degradation are initiated from chaperone-bound states
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