Violência nas aulas de Educação Física escolar: uma revisão da produção científica no Brasil de 2017 a 2022

Objetivou-se levantar a produção científica na literatura sobre violência nas aulas de EF escolar nos últimos 5 anos. Desenvolveu-se uma revisão sistemática sobre a temática de violência nas áreas da Educação e EF através do método PRISMA. As bases consultadas foram Scielo, Lilacs, Scopus e Google Acadêmico, durante setembro/2022-outubro/2022. Foram encontrados 1028 estudos e, após aplicados os filtros de seleção, chegou-se a 14 trabalhos. Percebeu-se uma ascendência de pesquisas relacionadas à violência escolar e EF de cunho qualitativo e predominantes nas regiões Sudeste e Sul do Brasil. Os dados mostram que os cursos de formação de professores de EF ainda carecem de informações sobre o fenômeno da violência escolar, questão que afeta a vivência pedagógica dos docentes, uma vez que a postura do professor pode gerar e/ou intensificar atos de violência ao corpo docente e discente, tendo a escola, muitas vezes, um papel omisso frente à problemática

Análise de falha na conformação mecânica das juntas soldadas durante o processo de fabricação de dutos flexíveis: Analysis of failure in the mechanical conformation of the welded joint in the production process of flexible pipes

Por definição os materiais falham quando as tensões atuantes excedem a resistência do material, entretanto, as tensões aplicadas podem ser amplificadas devido a alguns fatores que chamamos de concentradores de tensão, fazendo com que ocorra a falha de um material em tensões menores que o esperado. Este artigo apresenta uma síntese das análises realizadas durante o acompanhamento de produção, no intuito de observar e estudar o fenômeno de falha das juntas soldadas durante o processo de fabricação de dutos flexíveis de aço inoxidável duplex UNS S31803 / S32205 ao longo do ano de 2022

Return of Thoroughbred Racing Horses to the Races after Treating Slab Fractures of the Third Carpal Bone with PRP and Stem Cells

 Background: Despite the fact that slab fracture of the third carpal bone is an event of great worldwide relevance in racehorses, the third carpal fracture doesn’t have data on treatments and return to racing in Brazil. The search for efficient treatments and which provide recovery providing horses return to racing is an objective of sports equine medicine. Regenerative therapies like Platelet Rich Plasma (PRP) and Stem Cells (MSc) have demonstrated a great potential in the treatment of several injuries. For the treatment of three Thoroughbred racing horses at Brazilian Jockey Club, with sagittal plane slab fractures of the third carpal bone, we used the association of PRP and Stem Cells for reduction of the rest and good return to conditions athletics of these horses.Cases: Three Thoroughbred racing horses, males, 4 and 5 years old, showed slab fracture third carpal bone in different moments of their activity at Brazilian Jockey Club. Usually, the treatment for this type of fracture is the arthroscopic repair and the conservative management. We performed after initial radiographic evaluation dorsoproximal-dorsodistal oblique (DPr-DDiO) “skyline”, intra-articular applications of PRP and MSCs. The treatments were performed according to the radiographic follow-up of the lesion evolution. No other treatment was performed concomitantly with cell therapy in the 3 treated patients. Three treatments were performed in the first patient and 2 in the second and third patients. Before each treatment for all patients, we performed radiography dorsoproximal-dorsodistal oblique (DPr-DDiO) ‘skyline’ of the carpus. After this step, the animal was sedated with 10% xylazine hydrochloride at a dose of 0.5 mg/kg intravenously. Antisepsis of the carpus was performed and applied with radiographic monitoring of the needle positioning, first the PRP in the volume of 2 mL and in sequence, 20 million cells MSCs suspended in autologous plasma from the cell bank of the Cellen veterinary stem cell laboratory, totalizing 4 mL. The 3 horses returned to their training routines and continued to be monitored by clinical examinations and radiography, there were no post-treatment complications and all ran again in the median time of 253 days after the first application of PRP and stem cells. Everyone won the first race after treatment.Discussion: The 3 patients suffered the fractures after running at the Brazilian Jockey Club. All fractures were simple- no comminuted slab fractures of the third carpal. In our study, we chose to carry out the treatments with PRP and MSCs by intra-articular application. The regenerative medicine occupies a prominent place in recovery from injuries and the association of PRP and MSCs have played an important role in the treatment of athlete horses in tendons, bones and joint injuries and our work, the treatment was effective, without complications, helped to reduce local inflammation, perceptually reducing the pain observed before the application and the animals started running again with a quality equivalent to that observed before the occurrence of injuries. This way, our results demonstrated that the association PRP and MSCs was effective in recovering the 3 patients, all of them ran after injury. The median time for racing was 253 days and the horses won their first races after fractures occurred. These results encourage the use of the association of PRP and MSCs also for no comminuted sagittal plane slab fractures of the third carpal in Thoroughbred Racing horses

Ação odontológica na triagem neonatal direcionada ao hipotireoidismo congênito

O hipotireoidismo congênito é um distúrbio endócrino caracterizado pela diminuição dos níveis séricos dos hormônio da glândula tireóide. Este afeta o metabolismo do cálcio, e, portanto, a formação dos ossos e dentes. É comum nestes pacientes anomalias de formação dentária, atraso na erupção dentária, hipodesenvolvimento do côndilo mandibular e macroglossia. Somados, estes fatores podem ainda levar a uma má-oclusão e ao desenvolvimento inadequado das funções orais. Diante do exposto, Avaliou-se através deste estudo as condições clínicas orais e promoveu-se o atendimento odontológico dos pacientes com esta disfunção endócrina vinculados ao serviço de triagem neonatal do Hospital Universitário da Universidade Federal de Sergipe. Trata-se de um projeto de extensão em que foram atendidos 205 pacientes com idade entre 01 mês e 14 anos, no período de fevereiro à novembro de 2016, os quais passaram por uma avaliação clínica e receberam orientações preventivas. A partir do exame clínico, observou-se que 20% dos pacientes apresentavam alguma necessidade de tratamento odontológico, sendo esses, agendados e encaminhados para a realização do procedimento clínico odontológico. Com os dados obtidos foi possível concluir que é essencial dar aos responsáveis e pacientes as informações necessárias para a prevenção de doenças bucais, estando elas correlacionadas ou não com o Hipotireoidismo Congênito. Além disto, a realização de tratamento clínico, preventivo e curativo nesses pacientes, agregou a Odontologia ao plano multiprofissional já existente representado pelo programa de triagem neonatal do HU – UFS

ICD for Sudden Cardiac Death Prevention and New Pharmaceutical Treatment Options in Hypertrophic Obstructive Cardiomyopathy

In humans, hypertrophic cardiomyopathy (HCM) is a heterogeneous cardiac illness typically caused by autosomal dominant sarcomeric gene mutations and characterized by reduced heart’s compliance, myofibrillar disarray, and fibrosis of the heart. Areas covered: Although HCM was formerly viewed as a malignant disease entity with few treatment choices, effective management strategies have emerged so that affected individuals may expect to have a normal lifespan without the need for pacing or another type of invasive intervention. Herein, these management strategies are discussed. There is no curative treatment for HCM that reverses or prevents hypertrophy and heart dysfunction. Drug-based therapies aim to alleviate its symptoms and slow disease progression. Mavacamten is a reversible cardiac myosin allosteric modulator with a potential therapeutic effect for obstructive HCM. Mavacamten markedly improved the health status of patients with symptomatic obstructive hypertrophic cardiomyopathy compared with a placebo. In patients with HOCM, the importance of an implantable cardioverter defibrillators (ICD) is to prevent sudden cardiac death (SCD). Approximately 25% of those with HCM suffer from atrial arrhythmias, and the condition is notoriously difficult to manage. Anti-arrhythmic drugs, such as sotalol, amiodarone, and disopyramide, are routinely prescribed. Radiofrequency ablations for atrial fibrillation in patients with HCM have become more common despite their limited effectiveness (about 70% recurrence)

ABORDAGENS DIAGNÓSTICAS E TERAPÊUTICAS DA SÍNDROME DE CUSHING: UMA REVISÃO BIBLIOGRÁFICA DE LITERATURA

Introduction: Cushing's Syndrome is a rare and complex endocrine condition characterized by a chronic increase in cortisol levels in the body, which can result in a variety of significant physical and metabolic symptoms. Objective: This study aims to explore recent advances and discoveries in the diagnosis and treatment of Cushing's Syndrome. Methods: A literature review of the last 15 years was carried out, including original studies and reviews, with specific inclusion criteria to address Cushing's Syndrome. Results and Discussion: The etiology of Cushing's Syndrome is multifaceted, reflecting the complexity of this endocrine condition. Standard diagnostic methods for Cushing's Syndrome include laboratory tests to evaluate cortisol and ACTH levels in blood, urine and saliva, as well as imaging tests to locate the source of hormone overproduction. Therapeutic options for Cushing's Syndrome, as evidenced by the review of current studies, present a wide range of approaches, including surgery, drug therapy and radiotherapy Conclusion: The review emphasizes the importance of education and awareness about Cushing's Syndrome among healthcare professionals. health, patients and caregivers, in order to facilitate early diagnosis, access to appropriate treatment and necessary emotional support.Introducción: El síndrome de Cushing es uma afección endocrina rara y compleja caracterizada por un aumento crónico de los niveles de cortisol en el cuerpo, que puede provocar una variedad de síntomas físicos y metabólicos importantes. Objetivo: Este estudio tiene como objetivo explorar los avances y descubrimientos recientes en el diagnóstico y tratamiento del síndrome de Cushing. Métodos: Se realizó una revisión de la literatura de los últimos 15 años, incluyendo estudios originales y revisiones, con criterios de inclusión específicos para abordar el Síndrome de Cushing. Resultados y Discusión: La etiología del Síndrome de Cushing es multifacética, lo que refleja la complejidad de esta condición endocrina. Los métodos de diagnóstico estándar para el síndrome de Cushing incluyen pruebas de laboratorio para evaluar los niveles de cortisol y ACTH en sangre, orina y saliva, así como pruebas de imágenes para localizar la fuente de la sobreproducción hormonal. Las opciones terapéuticas para el síndrome de Cushing, como lo demuestra la revisión de los estudios actuales, presentan una amplia gama de enfoques, que incluyen cirugía, terapia con medicamentos y radioterapia. Conclusión: La revisión enfatiza la importancia de la educación y la concientización sobre el síndrome de Cushing entre los profesionales de la salud. y cuidadores, con el fin de facilitar el diagnóstico precoz, el acceso al tratamiento adecuado y al apoyo emocional necesario.A Síndrome de Cushing é uma condição endócrina rara e complexa, caracterizada pelo aumento crônico dos níveis de cortisol no organismo, que pode resultar em uma variedade de sintomas físicos e metabólicos significativos. Objetivo: Este estudo visa explorar avanços e descobertas recentes no diagnóstico e tratamento da Síndrome de Cushing. Métodos: Realizou-se uma revisão bibliográfica dos últimos 15 anos, incluindo estudos originais e revisões, com critérios de inclusão específicos para abordar sobre a Síndrome de Cushing. Resultados e Discussão: A etiologia da Síndrome de Cushing é multifacetada, refletindo a complexidade dessa condição endócrina. Os métodos diagnósticos padrão para a Síndrome de Cushing incluem testes laboratoriais para avaliar os níveis de cortisol e ACTH no sangue, urina e saliva, bem como exames de imagem para localizar a fonte da hiperprodução hormonal. As opções terapêuticas para a Síndrome de Cushing, conforme evidenciado na revisão dos estudos atuais, apresentam uma ampla gama de abordagens, incluindo cirurgia, terapia medicamentosa e radioterapia Conclusão: A revisão enfatiza a importância da educação e conscientização sobre a Síndrome de Cushing entre profissionais de saúde, pacientes e cuidadores, a fim de facilitar o diagnóstico precoce, o acesso ao tratamento adequado e o apoio emocional necessário.Introdução: A Síndrome de Cushing é uma condição endócrina rara e complexa, caracterizada pelo aumento crônico dos níveis de cortisol no organismo, que pode resultar em uma variedade de sintomas físicos e metabólicos significativos. Objetivo: Este estudo visa explorar avanços e descobertas recentes no diagnóstico e tratamento da Síndrome de Cushing. Métodos: Realizou-se uma revisão bibliográfica dos últimos 15 anos, incluindo estudos originais e revisões, com critérios de inclusão específicos para abordar sobre a Síndrome de Cushing. Resultados e Discussão: A etiologia da Síndrome de Cushing é multifacetada, refletindo a complexidade dessa condição endócrina. Os métodos diagnósticos padrão para a Síndrome de Cushing incluem testes laboratoriais para avaliar os níveis de cortisol e ACTH no sangue, urina e saliva, bem como exames de imagem para localizar a fonte da hiperprodução hormonal. As opções terapêuticas para a Síndrome de Cushing, conforme evidenciado na revisão dos estudos atuais, apresentam uma ampla gama de abordagens, incluindo cirurgia, terapia medicamentosa e radioterapia Conclusão: A revisão enfatiza a importância da educação e conscientização sobre a Síndrome de Cushing entre profissionais de saúde, pacientes e cuidadores, a fim de facilitar o diagnóstico precoce, o acesso ao tratamento adequado e o apoio emocional necessário

Initial Development of Hymeneae courbaril (Linnaeus.) (FABACEAE) under inoculation of edophytic bacteria from Bacillus and Herbaspirillum genus / Desenvolvimento inicial de Hymeneae courbaril (Linnaeus.) (FABACEAE) sob inoculação de bactérias endofíticas dos gêneros Bacillus e Herbaspirillum

The rise of environmental problems and the need for recovery of degraded areas have caused interest in the knowledge of native Brazilian species. One of the major barriers to replanting native forests is the production of seedlings of species that can fuel reforestation programs. Hymenaea courbaril is a forest species, has great forest and environmental importance and is very suitable for plants in degraded areas, which can be restored by vegetation, recommended for silvipastoral, pasture afforestation and others. One of the major barriers to replanting native forests is the production of seedlings of species that can fuel reforestation programs. One solution is how growth promoting bacteria that are part of the plant's resident population and are not phytopathogenic. These bacteria can be used to treat micropropagated seeds, explants and seedlings incorporated into the plant substrate. Thus, due to the lack of studies with growth-promoting bacteria in tree species, the aim of this work is to evaluate or development of H. courbaril seedlings. Inoculants are inoculated with growth-promoting endophytes using biometric parameters such as plant size. collection, leaf number, plant height, root system length, biomass and dry matter of shoot and root system. In general the bacteria Herbaspirillum sp. the best result was obtained when an inoculation directly in the soil, presenting greater development of biometric characters. For the genus Bacillus sp. seed inoculation provided further development of the plants. This study contributes to future research and recommends the use of microbial agents to promote H. courbaril growth.The rise of environmental problems and the need for recovery of degraded areas have caused interest in the knowledge of native Brazilian species. One of the major barriers to replanting native forests is the production of seedlings of species that can fuel reforestation programs. Hymenaea courbaril is a forest species, has great forest and environmental importance and is very suitable for plants in degraded areas, which can be restored by vegetation, recommended for silvipastoral, pasture afforestation and others. One of the major barriers to replanting native forests is the production of seedlings of species that can fuel reforestation programs. One solution is how growth promoting bacteria that are part of the plant's resident population and are not phytopathogenic. These bacteria can be used to treat micropropagated seeds, explants and seedlings incorporated into the plant substrate. Thus, due to the lack of studies with growth-promoting bacteria in tree species, the aim of this work is to evaluate or development of H. courbaril seedlings. Inoculants are inoculated with growth-promoting endophytes using biometric parameters such as plant size. collection, leaf number, plant height, root system length, biomass and dry matter of shoot and root system. In general the bacteria Herbaspirillum sp. the best result was obtained when an inoculation directly in the soil, presenting greater development of biometric characters. For the genus Bacillus sp. seed inoculation provided further development of the plants. This study contributes to future research and recommends the use of microbial agents to promote H. courbaril growth

Checklist of the dipterofauna (Insecta) from Roraima, Brazil, with special reference to the Brazilian Ecological Station of Maracá

Roraima is a Brazilian state located in the northern portion of the Amazon basin, with few studies regarding its biodiversity. The Ecological Station of Maracá (Brazil, state of Roraima) harbors the third largest Brazilian pluvial island and is composed of a transitional landscape of savanna and Amazon rainforest components. Despite its ecological importance and strategic localization, few studies covered the dipterofauna of this locality. An updated checklist addressing 41 families of true flies (Diptera) occurring in Roraima is presented based on the literature and the specimens collected during a field expedition that occurred in 2015. This checklist brings several improvements such as new records of 165 taxa to the state of Roraima, 29 taxa to Brazil, and 259 morphotypes, mostly likely representing undescribed species

COVID-19 outcomes in people living with HIV: Peering through the waves

Objective: To evaluate clinical characteristics and outcomes of COVID-19 patients infected with HIV, and to compare with a paired sample without HIV infection. Methods: This is a substudy of a Brazilian multicentric cohort that comprised two periods (2020 and 2021). Data was obtained through the retrospective review of medical records. Primary outcomes were admission to the intensive care unit, invasive mechanical ventilation, and death. Patients with HIV and controls were matched for age, sex, number of comorbidities, and hospital of origin using the technique of propensity score matching (up to 4:1). They were compared using the Chi-Square or Fisher's Exact tests for categorical variables and the Wilcoxon for numerical variables. Results: Throughout the study, 17,101 COVID-19 patients were hospitalized, and 130 (0.76%) of those were infected with HIV. The median age was 54 (IQR: 43.0;64.0) years in 2020 and 53 (IQR: 46.0;63.5) years in 2021, with a predominance of females in both periods. People Living with HIV (PLHIV) and their controls showed similar prevalence for admission to the ICU and invasive mechanical ventilation requirement in the two periods, with no significant differences. In 2020, in-hospital mortality was higher in the PLHIV compared to the controls (27.9% vs. 17.7%; p = 0.049), but there was no difference in mortality between groups in 2021 (25.0% vs. 25.1%; p > 0.999). Conclusions: Our results reiterate that PLHIV were at higher risk of COVID-19 mortality in the early stages of the pandemic, however, this finding did not sustain in 2021, when the mortality rate is similar to the control group