16 research outputs found
Grid Code-Dependent Frequency Control Optimization in Multi-Terminal DC Networks
The increasing deployment of wind power is reducing inertia in power systems.
High-voltage direct current (HVDC) technology can help to improve the stability of AC areas in
which a frequency response is required. Moreover, multi-terminal DC (MTDC) networks can be
optimized to distribute active power to several AC areas by droop control setting schemes that adjust
converter control parameters. To this end, in this paper, particle swarm optimization (PSO) is used
to improve the primary frequency response in AC areas considering several grid limitations and
constraints. The frequency control uses an optimization process that minimizes the frequency nadir
and the settling time in the primary frequency response. Secondly, another layer is proposed for the
redistribution of active power among several AC areas, if required, without reserving wind power
capacity. This method takes advantage of the MTDC topology and considers the grid code limitations
at the same time. Two scenarios are defined to provide grid code-compliant frequency control.Australian Education International, Australian Government TEC2016-80242-PMinisterio de Economía y Competitividad DPI2016-75294-C2-2-
Potentials and Technical Requirements for the Provision of Ancillary Services in Future Power Systems with Distributed Energy Resources
A decentralized supply of electrical power based on renewable energies paves the way to a sustainable power supply without nuclear energy and without the emission of greenhouse gases. This energy transition (Energiewende) entails challenges regarding the provision of Ancillary Services (AS), associated with intermittent in-feed of Distributed Energy
Resources (DER) into the distribution grids. In this paper, the demand, potentials, and technical requirements for AS provision in Germany, especially in the state of Lower Saxony, are discussed. These aspects are considered from multiple perspectives across all voltage levels. Beginning with a steady state analysis that focuses on the transmission grid, an
expected increment in voltage violations and line congestions is revealed. Counteracting the resulting technical limit violations requires consideration of distribution grid flexibilities among others. To address this emerging demand, the potentials for the provision of AS by components in the distribution grids are identified. However, technical concepts are also required to exploit the potential, as DER in-feed has significant impact on the functionality of conventional protection systems. The analysis in this paper indicates the need for development of concepts to provide AS in the distribution grid and detailed technical requirements within a holistic simulative approach
Cross-sectional observational study of 208 patients with non-classical urea cycle disorders
Urea cycle disorders (UCDs) are inherited disorders of ammonia detoxification often regarded as mainly of relevance to pediatricians. Based on an increasing number of case studies it has become obvious that a significant number of UCD patients are affected by their disease in a non-classical way: presenting outside the newborn period, following a mild course, presenting with unusual clinical features, or asymptomatic patients with only biochemical signs of a UCD. These patients are surviving into adolescence and adulthood, rendering this group of diseases clinically relevant to adult physicians as well as pediatricians. In preparation for an international workshop we collected data on all patients with non-classical UCDs treated by the participants in 20 European metabolic centres. Information was collected on a cohort of 208 patients 50% of which were ≥ 16 years old. The largest subgroup (121 patients) had X-linked ornithine transcarbamylase deficiency (OTCD) of whom 83 were female and 29% of these were asymptomatic. In index patients, there was a mean delay from first symptoms to diagnosis of 1.6 years. Cognitive impairment was present in 36% of all patients including female OTCD patients (in 31%) and those 41 patients identified presymptomatically following positive newborn screening (in 12%). In conclusion, UCD patients with non-classical clinical presentations require the interest and care of adult physicians and have a high risk of neurological complications. To improve the outcome of UCDs, a greater awareness by health professionals of the importance of hyperammonemia and UCDs, and ultimately avoidance of the still long delay to correctly diagnose the patients, is crucial
The James Webb Space Telescope Mission
Twenty-six years ago a small committee report, building on earlier studies,
expounded a compelling and poetic vision for the future of astronomy, calling
for an infrared-optimized space telescope with an aperture of at least .
With the support of their governments in the US, Europe, and Canada, 20,000
people realized that vision as the James Webb Space Telescope. A
generation of astronomers will celebrate their accomplishments for the life of
the mission, potentially as long as 20 years, and beyond. This report and the
scientific discoveries that follow are extended thank-you notes to the 20,000
team members. The telescope is working perfectly, with much better image
quality than expected. In this and accompanying papers, we give a brief
history, describe the observatory, outline its objectives and current observing
program, and discuss the inventions and people who made it possible. We cite
detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space
Telescope Overview, 29 pages, 4 figure
Cross-sectional observational study of 208 patients with non-classical urea cycle disorders
Urea cycle disorders (UCDs) are inherited disorders of ammonia detoxification often regarded as mainly of relevance to pediatricians. Based on an increasing number of case studies it has become obvious that a significant number of UCD patients are affected by their disease in a non-classical way: presenting outside the newborn period, following a mild course, presenting with unusual clinical features, or asymptomatic patients with only biochemical signs of a UCD. These patients are surviving into adolescence and adulthood, rendering this group of diseases clinically relevant to adult physicians as well as pediatricians. In preparation for an international workshop we collected data on all patients with non-classical UCDs treated by the participants in 20 European metabolic centres. Information was collected on a cohort of 208 patients 50% of which were ≥ 16 years old. The largest subgroup (121 patients) had X-linked ornithine transcarbamylase deficiency (OTCD) of whom 83 were female and 29% of these were asymptomatic. In index patients, there was a mean delay from first symptoms to diagnosis of 1.6 years. Cognitive impairment was present in 36% of all patients including female OTCD patients (in 31%) and those 41 patients identified presymptomatically following positive newborn screening (in 12%). In conclusion, UCD patients with non-classical clinical presentations require the interest and care of adult physicians and have a high risk of neurological complications. To improve the outcome of UCDs, a greater awareness by health professionals of the importance of hyperammonemia and UCDs, and ultimately avoidance of the still long delay to correctly diagnose the patients, is crucial
Can We Identify Patients with High Risk of Osteoarthritis Progression Who Will Respond to Treatment? A Focus on Biomarkers and Frailty
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Research Projekt SiNED Insights - Ancillary services for Reliable Power Grids in times of the Progressive German Energiewende and Digital Transformation
Ancillary services in future power systems have to be provided by decentralized distributed energy resources, resulting
in various, interdisciplinary issues. Focusing on the three competence areas (Electrical Power Engineering, Digital
Transformation/Information and Communication Technology, and Energy Law and Economics), insights for the central
research goals of the project are presented (after three of five years of project duration). While results indicate, that the
future ancillary services demand of a climate-neutral power system can be supplied with further developments, open
questions and issues still remain. The interdisciplinary studies of the SiNED consortium show that it will be possible to
provide ancillary services also from the lower voltage levels, both technically and economically. These results and the
necessary regulatory frameworks are discussed in this paper
SiNED-Ancillary Services for Reliable Power Grids in Times of Progressive German Energiewende and Digital Transformation
Within SiNED research project, several members of the Energy Research Centre of Lower Saxony (Energieforschungszentrum Niedersachsen, EFZN) are working on various issues relating to the future provision of
ancillary services and to future congestion management. The questions include energy technology, economic and energy law aspects as well as information and communications technology (ICT) and data. The investigations are based on Lower Saxony and the framework conditions there. The temporal focus of the investigations is the year 2030