Psychological Distress and Psychosocial Factors in the Non-Formal Context of Basketball Coaches in Times of the COVID-19 Pandemic

Psychological distress and psychosocial factors are studied in the sports context in players of various specialties, but are only little studied with coaches who carry out their work with these athletes; that is where we put the emphasis, trying to determine the perception of coaches on psychological distress and psychosocial risk factors that may influence their sports work in times of a pandemic. It is an ex post facto study with a single-group retrospective design, with a representative sample of 94 coaches out of a possible 109. The Kessler Psychological Distress Scale and the short version of the ISTAS21 Psychosocial Risk Assessment at Work Questionnaire were adapted to the sports context. The results show that the youngest, those with the least experience and level 1 and level 2 coaches show the highest levels of stress. According to the psychosocial risk assessment, level 1 and 2 coaches, with experience between 6 to 10 years, are in the risk zone. Therefore, it is important to work with a group of coaches who are in the psychosocial risk zone and with high levels of psychological discomfort in order to avoid mental, emotional and physical stress, for the good performance of their work in the best possible conditions

Análisis de variables relacionadas con el acceso y desempeño de las funciones directiva y docente en las nuevas universidades populares españolas. Un estudio a nivel nacional

Cada vez y con más frecuencia las instituciones de educación no formal están cobrando una mayor importancia en la formación continua de nuestros ciudadanos. El presente trabajo recoge una investigación realizada a nivel nacional sobre una de estas instituciones que en la actualidad cuenta con más de dos millones de alumnos. Estamos hablando de las Universidades Populares españolas que en la actualidad se encuentran expandidas por veintidós provincias de once comunidades autónomas: Andalucía, Aragón, Castilla La Mancha, Castilla León, Extremadura, Galicia, La Rioja, Madrid, Murcia y Valencia. En esta investigación se utilizaron tres tipos de cuestionarios dirigidos a cada uno de los estamentos ligados a este proyecto: los directivos, los monitores y los alumnos. A su vez, se realizó un estudio de caso en la Universidad Popular de Loja (Granada), con el objetivo de dotar de significado a los datos estadísticos obtenidos del estudio a nivel nacional. De esta forma se han caracterizado y descrito las principales tareas de las Universidades Populares españolas y la visión que de ellas tienen los tres grupos implicados en su vida diari

¿Puede explicar la teoría del flujo las diferencias de rendimiento escolar entre los niños con y sin TDAH?

En este estudio se comprueba la relación del rendimiento escolar con el tiempo dedicado al estudio, las metas propuestas y las habilidades percibidas. La muestra ha estado compuesta por 121 alumnos con TDAH y 124 sin ningún tipo de trastorno. Se ha utilizado un diseño transversal comparando los resultados de ambos grupos. Los resultados obtenidos muestran que el grupo con TDAH dedica menos horas de estudio, se propone menos metas y sus habilidades percibidas son menores. En el grupo con TDAH el rendimiento está asociado a las metas y a las habilidades percibidas, pero no al tiempo. En cambio, en el grupo sin TDAH el rendimiento está relacionado con tiempo, metas y habilidades percibidas. El rendimiento escolar del grupo con TDAH ha sido explicado tanto por las metas como por las habilidades percibidas y en el grupo sin TDAH sólo ha estado explicado por las habilidades percibidas. Se discuten estos resultados y se proponen futuras líneas de investigación

Estudio sobre el proceso de enseñanza-aprendizaje en las universidades populares españolas. Una visión desde los propios implicados

This study tries to know the process education-learning in one the institutions less well-known nonFormal Education in Spain: the Popular Universitires. The study took I finish at national level by means of a descriptive methodology using three types different from questionnaires (directors, monitors and participants) like techniqueof collection of data. As well, these data were equipped with meaning by means of a study of case in the Popular University of Loja (Granada) in which were used like techniques of collection of data the semistructured interviews, groups of discussion and institutional document analysis. Between the most important conclusions we can emphasize than the education-learning process takes like fundamental axis the student (learning rate, motivation, individualized education…).Este estudio trata de conocer el proceso de enseñanza-aprendizaje en una de las instituciones de Educación no Formal menos conocida en España: las Universidades Populares. El estudio se llevó acabo a nivel nacional mediante una metodología descriptiva utilizando tres tipos distintos de cuestionarios (directivos, monitores y participantes) como técnica de recogida de datos. A su vez, estos datos fueron dotados de significado mediante un estudio de caso en la Universidad Popular de Loja (Granada) en el que se utilizaron como técnicas de recogida de datos las entrevistas semiestructuradas, grupos de discusión y análisis de documentos institucionales. Entre las conclusiones más importantes podemos destacar que el proceso de enseñanza-aprendizaje toma como eje fundamental al alumno (ritmo de aprendizaje, motivación, enseñanza individualizada…)

Predictors of Response to Exclusive Enteral Nutrition in Newly Diagnosed Crohn´s Disease in Children: PRESENCE Study from SEGHNP

Exclusive enteral nutrition (EEN) has been shown to be more effective than corticosteroids in achieving mucosal healing in children with Crohn´s disease (CD) without the adverse effects of these drugs. The aims of this study were to determine the efficacy of EEN in terms of inducing clinical remission in children newly diagnosed with CD, to describe the predictive factors of response to EEN and the need for treatment with biological agents during the first 12 months of the disease. We conducted an observational retrospective multicentre study that included paediatric patients newly diagnosed with CD between 2014–2016 who underwent EEN. Two hundred and twenty-two patients (140 males) from 35 paediatric centres were included, with a mean age at diagnosis of 11.6 ± 2.5 years. The median EEN duration was 8 weeks (IQR 6.6–8.5), and 184 of the patients (83%) achieved clinical remission (weighted paediatric Crohn’s Disease activity index [wPCDAI] 15 mg/L and ileal involvement tended to respond better to EEN. EEN administered for 6–8 weeks is effective for inducing clinical remission. Due to the high response rate in our series, EEN should be used as the first-line therapy in luminal paediatric Crohn’s disease regardless of the location of disease and disease activityS

Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases

Objective Clinical heterogeneity, a hallmark of systemic autoimmune diseases, impedes early diagnosis and effective treatment, issues that may be addressed if patients could be classified into groups defined by molecular pattern. This study was undertaken to identify molecular clusters for reclassifying systemic autoimmune diseases independently of clinical diagnosis. Methods Unsupervised clustering of integrated whole blood transcriptome and methylome cross-sectional data on 955 patients with 7 systemic autoimmune diseases and 267 healthy controls was undertaken. In addition, an inception cohort was prospectively followed up for 6 or 14 months to validate the results and analyze whether or not cluster assignment changed over time. Results Four clusters were identified and validated. Three were pathologic, representing “inflammatory,” “lymphoid,” and “interferon” patterns. Each included all diagnoses and was defined by genetic, clinical, serologic, and cellular features. A fourth cluster with no specific molecular pattern was associated with low disease activity and included healthy controls. A longitudinal and independent inception cohort showed a relapse–remission pattern, where patients remained in their pathologic cluster, moving only to the healthy one, thus showing that the molecular clusters remained stable over time and that single pathogenic molecular signatures characterized each individual patient. Conclusion Patients with systemic autoimmune diseases can be jointly stratified into 3 stable disease clusters with specific molecular patterns differentiating different molecular disease mechanisms. These results have important implications for future clinical trials and the study of nonresponse to therapy, marking a paradigm shift in our view of systemic autoimmune diseases

Measurement of the cosmic ray spectrum above 4×10184{\times}10^{18} eV using inclined events detected with the Pierre Auger Observatory

A measurement of the cosmic-ray spectrum for energies exceeding $4{\times}10^{18}$ eV is presented, which is based on the analysis of showers with zenith angles greater than $60^{\circ}$ detected with the Pierre Auger Observatory between 1 January 2004 and 31 December 2013. The measured spectrum confirms a flux suppression at the highest energies. Above $5.3{\times}10^{18}$ eV, the "ankle", the flux can be described by a power law $E^{-\gamma}$ with index $\gamma=2.70 \pm 0.02 \,\text{(stat)} \pm 0.1\,\text{(sys)}$ followed by a smooth suppression region. For the energy ($E_\text{s}$) at which the spectral flux has fallen to one-half of its extrapolated value in the absence of suppression, we find $E_\text{s}=(5.12\pm0.25\,\text{(stat)}^{+1.0}_{-1.2}\,\text{(sys)}){\times}10^{19}$ eV.Comment: Replaced with published version. Added journal reference and DO

Effect of viral storm in patients admitted to intensive care units with severe COVID-19 in Spain: a multicentre, prospective, cohort study

Background: The contribution of the virus to the pathogenesis of severe COVID-19 is still unclear. We aimed to evaluate associations between viral RNA load in plasma and host response, complications, and deaths in critically ill patients with COVID-19. Methods: We did a prospective cohort study across 23 hospitals in Spain. We included patients aged 18 years or older with laboratory-confirmed SARS-CoV-2 infection who were admitted to an intensive care unit between March 16, 2020, and Feb 27, 2021. RNA of the SARS-CoV-2 nucleocapsid region 1 (N1) was quantified in plasma samples collected from patients in the first 48 h following admission, using digital PCR. Patients were grouped on the basis of N1 quantity: VIR-N1-Zero ([removed]2747 N1 copies per mL). The primary outcome was all-cause death within 90 days after admission. We evaluated odds ratios (ORs) for the primary outcome between groups using a logistic regression analysis. Findings: 1068 patients met the inclusion criteria, of whom 117 had insufficient plasma samples and 115 had key information missing. 836 patients were included in the analysis, of whom 403 (48%) were in the VIR-N1-Low group, 283 (34%) were in the VIR-N1-Storm group, and 150 (18%) were in the VIR-N1-Zero group. Overall, patients in the VIR-N1-Storm group had the most severe disease: 266 (94%) of 283 patients received invasive mechanical ventilation (IMV), 116 (41%) developed acute kidney injury, 180 (65%) had secondary infections, and 148 (52%) died within 90 days. Patients in the VIR-N1-Zero group had the least severe disease: 81 (54%) of 150 received IMV, 34 (23%) developed acute kidney injury, 47 (32%) had secondary infections, and 26 (17%) died within 90 days (OR for death 0·30, 95% CI 0·16–0·55; p<0·0001, compared with the VIR-N1-Storm group). 106 (26%) of 403 patients in the VIR-N1-Low group died within 90 days (OR for death 0·39, 95% CI 0·26–0·57; p[removed]11 página