propuesta de gestión tecnológica para la solicitud de un servicio de emergencia e inspección comercial Bomberil

se adjuntan en el trabajo 18 anexos, dentro de los cuales se encuentran, articulos de decretos, leyes y normatividad, de igual manera se adjuntan diferentes gráficas dentro de las cuales se muestran tortas de los análisis de la investigación, y se adjunta como ultimo anexo una propuesta un posible aplicativo móvil, que pudiera servir como posible solución a la problemática analizada en el trabajo de investigación.La unidad administrativa Cuerpo Oficial de Bomberos Bogotá, entidad del estado atiende las solicitudes de la ciudadanía y previene incendios. Esta unidad no cuenta con un mecanismo que permita acceder a la información y solicitar servicios mediante plataformas tecnológicas. Consecuentemente, surge la necesidad de proponer un modelo de gestión de procesos que lo permita. En este sentido, se realizó una investigación proyectiva, la cual se fundamentó en un estudio de campo, mediante administración de encuestas al momento de atender los servicios, y un análisis documental. Con la información obtenida, se apoyó en modelos de causalidad y de manera de manera teórica; en el modelo jerárquico de Thomas Saaty, con el fin de mejorar la toma de decisiones. Asimismo, se emplea la metodología BPM, para mejorar los procesos de la entidad. Dentro de los hallazgos, se encontraron la falta de procedimientos en la solicitud de inspecciones técnicas y herramientas de tecnología escasas, las cuales son esenciales para la interacción entre la comunidad y los procesos estudiados. Con los datos obtenidos se observan mejoras substanciales en los procesos, identificando dónde se encontraban las debilidades. La presente propuesta permitirá la mejora de dos procesos críticos internos de la unidad, lo que posibilitará encontrar información relacionada con inspecciones técnicas y solicitar un servicio de emergencias. Se podrán planificar, evaluar y desarrollar ambas actividades con mayor calidad. Este proyecto podrá ser apoyado en sus diferentes fases por la misma unidad administrativa. El modelo de gestión plantea una ayuda al procedimiento que ha sido poco efectivo, permitiendo, además, hacerlo mediante la estrategia de gobierno en línea.The administrative unit of the Official Bogota Fire Department, entity of the state, responds to citizens' requests and prevents fires. This unit does not have a mechanism that allows access to information and request services through technological platforms. Consequently, there is a need to propose a process management model that allows it. In this sense, a projective investigation was carried out, which was based on a field study, through the administration of surveys at the time of serving the services, and a documentary analysis. With the information obtained, supported by causality models and theoretically on the hierarchical model by Thomas Saaty was used in order to improve decision making. Likewise, the BPM methodology is used to improve the processes of the entity. Among the findings, there was a lack of procedures in the request for technical inspections and scarce technology tools, which are essential for the interaction between the community and the processes studied. With the obtained data, substantial improvements in the processes are observed, identifying where the weaknesses were. The present proposal will allow the improvement of two internal critical processes of the unit, which will make it possible to find information related to technical inspections and request an emergency service. You can plan, evaluate and develop both activities with higher quality. This project can be supported in its different phases by the same administrative unit. The management model proposes an aid to the procedure that has been ineffective, allowing, in addition, to do so through the online government strategy

Automatic discovery of 100-miRNA signature for cancer classification using ensemble feature selection

Lopez-Rincon A, Martinez-Archundia M, Martinez-Ruiz GU, Schönhuth A, Tonda A. Automatic discovery of 100-miRNA signature for cancer classification using ensemble feature selection. BMC Bioinformatics. 2019;20(1): 480

Evaluation of antiparasitic, anticancer, antimicrobial and hypoglycemic properties of organic extracts from Panamanian mangrove plants

To investigate 33 organic extracts of mangrove plants for: antiparasitic, anticancer, and antibacterial activities, as well as their ability to inhibit the activity of the 毩-glucosidase enzyme. Methods: Leaves from all different plant mangrove species located in five mangrove zones of the Pacific coast of Panama were collected according to standard procedures. Qualitative phytochemical analysis of the organic extracts was performed by thin layer chromatography. The antiparasitic activity against Plasmodium falciparum, Trypanosoma cruzi and Leishmania donovani, toxicity against Artemia salina, anticancer activity in MCF-7 cell line, and antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa of all organic extract were investigated according protocols stablished in our institution. Finally, the ability to inhibit the enzymatic activity of 毩-glucosidase was evaluated by monitoring the hydrolysis of p-nitrophenyl 毩-Dglucopyranoside. Results: Thirty-three different samples belonging to nine different species of vascular plants with seeds of true mangroves were collected. Triterpenoids, phenolics, and tannins were the main groups of compounds found in the sampled mangroves. Saponins, quinones, and coumarins were found in less than 50% of the samples. Laguncularia racemosa showed moderate activity against Plasmodium falciparum. None of the extracts presented anticancer activity. Rhizophora mangle exhibited potent activity against Staphylococcus aureus and Bacillus subtilis [(90.41±7.33)% and (96.02±6.14)% of inhibition]; Avicennia germinans and Conocarpus erectus had activity against Escherichia coli [(71.17±6.15)% and (60.60±5.13)% of inhibition, respectively]. About 60% of the mangroves showed 毩-glucosidase inhibitory activity. In particular, extracts from Laguncularia racemosa, Pelliciera rhizophorae, Conocarpus erectus, Mora oleifera, and Tabebuia palustris species showed 毩-glucosidase inhibitory potential, with IC50 values of (29.45±0.29), (20.60±0.70), (730.06±3.74), (25.59±0.37), and (853.39±5.30) µg/mL, respectively. Conclusions: Panamanian mangroves are mainly a promising potential source of hypoglycemic compounds, specifically 毩-glucosidase inhibitors. These results highlight the therapeutic virtues of extracts from American mangrove plants.To investigate 33 organic extracts of mangrove plants for: antiparasitic, anticancer, and antibacterial activities, as well as their ability to inhibit the activity of the 毩-glucosidase enzyme. Methods: Leaves from all different plant mangrove species located in five mangrove zones of the Pacific coast of Panama were collected according to standard procedures. Qualitative phytochemical analysis of the organic extracts was performed by thin layer chromatography. The antiparasitic activity against Plasmodium falciparum, Trypanosoma cruzi and Leishmania donovani, toxicity against Artemia salina, anticancer activity in MCF-7 cell line, and antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa of all organic extract were investigated according protocols stablished in our institution. Finally, the ability to inhibit the enzymatic activity of 毩-glucosidase was evaluated by monitoring the hydrolysis of p-nitrophenyl 毩-Dglucopyranoside. Results: Thirty-three different samples belonging to nine different species of vascular plants with seeds of true mangroves were collected. Triterpenoids, phenolics, and tannins were the main groups of compounds found in the sampled mangroves. Saponins, quinones, and coumarins were found in less than 50% of the samples. Laguncularia racemosa showed moderate activity against Plasmodium falciparum. None of the extracts presented anticancer activity. Rhizophora mangle exhibited potent activity against Staphylococcus aureus and Bacillus subtilis [(90.41±7.33)% and (96.02±6.14)% of inhibition]; Avicennia germinans and Conocarpus erectus had activity against Escherichia coli [(71.17±6.15)% and (60.60±5.13)% of inhibition, respectively]. About 60% of the mangroves showed 毩-glucosidase inhibitory activity. In particular, extracts from Laguncularia racemosa, Pelliciera rhizophorae, Conocarpus erectus, Mora oleifera, and Tabebuia palustris species showed 毩-glucosidase inhibitory potential, with IC50 values of (29.45±0.29), (20.60±0.70), (730.06±3.74), (25.59±0.37), and (853.39±5.30) µg/mL, respectively. Conclusions: Panamanian mangroves are mainly a promising potential source of hypoglycemic compounds, specifically 毩-glucosidase inhibitors. These results highlight the therapeutic virtues of extracts from American mangrove plants

A New Educational Escape-Room-Based Model for the Sustainable Valorization and Management of Cultural and Natural Heritage

Based on the model of the “escape room” game, the activity proposed in this paper centres on the historical site of one of the fiercest battles of the Spanish Civil War (February 1937). The battle site is in the area of Rivas-vaciamadrid, the focal point of the Francoist and Republican camps, which connected the centre of Madrid with one of the city’s most important logistics and military facilities, Alcalà de Henares. The study proposes a new way to use the site and, in particular, proposes a live game aimed at involving different types of participants, aligning it with their specific profiles, whether children, adults or scholars. Its main aim is to propose an activity for the sustainable valorization of this heritage and to raise awareness in participants about this significant piece of history as well as its preservation in the long-term. It should be kept in mind that “Los pueblos que desconocen su Historia están condenados a repetirla”, i.e. “Those who do not know their history are doomed to repeat it”.The Rivas-vaciamadrid site is also a source of information and study regarding geological, natural and historical-artistic aspects. One example is the Porphyrio porphiyrio (western swamphen), present in the ecosystem of Rivas-vaciamadrid, which has a noteworthy past having been depicted in the mosaics of both the "Villa Romana del Casale" in Sicily and the Church of "San Vitale", in Ravenna, Italy as well as being reported in writings by Aristotle and Pliny the Elder

Plataforma de Colaboración para la Investigación

En cuanto al uso de los conceptos para organizar el conocimiento, Hjorland indica que éstos son concebidos como unidades de pensamiento, y la relación interconceptual es un elemento fundamental ya que los paradigmas, con sus teorías y conceptualizaciones, son por naturaleza instrumentos clasificadores de la realidad con la que interactúa de continuo el individuo. De esta forma, las relaciones semánticas que se establecen entre los conceptos son básicas para sistematizar el conocimiento, pero su significado queda sujeto a la perspectiva teórica desde la cual sean considerados.Según la UNESCO (2005a) la diversidad de las modalidades de acceso al conocimiento constituye una de las características más importantes de la sociedad del aprendizaje y supone también, entre otras cosas, el cuestionamiento de los conceptos de inteligencia en los que prevalecía el carácter estable de los procesos de evaluación y trasmisión de los conocimientos. Así, en el contexto de la realidad actual, la tarea de discriminar información se vuelve un proceso casi imposible, la creciente información actual, principalmente por vía Internet, le resulta al pensamiento humano cada vez más difícil de filtrar, tratar y dominar; lo cual se traduce en barreras (número ilimitado de fuentes, desconocimiento de los mecanismos de filtrado, organización o apropiación cognitiva de la información) que impiden hacer un uso efectivo de ella. Así, el exceso de información no significa mejor comprensión de la realidad, sino que con frecuencia alarmante produce el efecto contrario (UNESCO, 2005a; Dudziacck 2003; Sahagún, 2004, citados por Peña, 2011)

Empirical Validation of a Class of Ray-Based Fading Models

As new wireless standards are developed, the use of higher operation frequencies comes in hand with new use cases and propagation effects that differ from the well-established state of the art. Numerous stochastic fading models have recently emerged under the umbrella of generalized fading conditions, to provide a fine-grain characterization of propagation channels in the mmWave and sub-THz bands. For the first time in literature, this work carries out an experimental validation of a class of such ray-based models, in a wide range of propagation conditions (anechoic, reverberation and indoor) at mmWave bands. We show that the independently fluctuating two-ray (IFTR) model has good capabilities to recreate rather dissimilar environments with high accuracy. We also put forth that the key limitations of the IFTR model arise in the presence of reduced diffuse propagation, and also due to a limited phase variability for the dominant specular components.Comment: 9 pages, 13 figure

Profile of the Spatial Distribution Patterns of the Human and Bacteriophage Virome in a Wastewater Treatment Plant Located in the South of Spain

The authors would like to acknowledge the support given by the Institute of Water Research of University of Granada and the disposition of Municipal Water Company of Granada (EMASAGRA S.A.) for financial support to carry out the research.In wastewater treatment plants, most microbial characterization has focused on bacterial, archaeal, and fungal populations. Due to the difficult isolation, quantification, and identification of viruses, only a limited number of virome studies associated with wastewater treatment plants have been carried out. However, the virus populations play an important role in the microbial dynamics in wastewater treatment systems and the biosafety of effluents. In this work, the viral members present in influent wastewater, mixed liquor (aerobic bioreactor), excess sludge, and effluent water of a conventional activated sludge system for the treatment of urban wastewater were identified. Viral members were observed by transmission electron microscopy and studied through next-generation sequencing studies. The results showed the dominance of bacteriophages in the viral community in all samples, with the dominant viral phylotype classified as Escherichia coli O157 typing phage 7. Moreover, different human viruses, such as Cynomolgus cytomegalovirus and Gammaherpesvirus, were also detected.Institute of Water Research of University of Granad

Significado psicológico de México entre niños

El objetivo del trabajo fue detectar el significado psicológico de "México" en niñas y niños. Se trabajó con 60 estudiantes de Primaria, repartidos equitativamente por género, con edades entre nueve y once años. Se utilizó la técnica original de redes semánticas naturales para obtener la información referente al significado psicológico de México. Las aplicaciones se hicieron de forma grupal en los salones de clase. Los resultados dejan ver que entre los participantes hubo una definición muy favorable de México, en la que los niños orientaron sus respuestas hacia los aspectos políticos, en comparación con las niñas, que definieron a México con base en sus bellezas naturales y las características afectivas de sus habitantes. Se observó que prevalece una tendencia instrumental en el género masculino, en contraste con la de tipo afectivo y expresivo del género femenino, rasgos propios de la cultura mexicana desde mucho tiempo atrás, que al parecer no registran cambios trascendentales en los papeles o roles asignados para cada uno de los géneros en México

Xanthinuria: a rare cause of urolithiasis in the cat

Xanthinuria is a very rare disease in cats. Its etiology may have a genetic origin or may be due to an iatrogenic xan- thine-dehydrogenase inhibition that nally results in urolithiasis. The present work reports two cases of xanthine uro- lithiasis in European Shorthair unrelated male and female cats. Both uroliths were analyzed by stereoscopic microsco- py, infrared spectroscopy and scanning electron microscopy. Besides the report of these two clinical cases, a detailed pathophysiologic review and some updated recommendations for diagnosis and treatment for this condition were done.La xantinuria es una patología que se presenta raramente en los gatos. Su etiología puede tener origen genético o de- berse a una inhibición yatrogénica de la enzima xantina deshidrogenasa, que generalmente se mani esta con urolitiasis. En este trabajo se informa el hallazgo de dos urolitos de xantina en dos gatos, un macho y una hembra, de raza Euro- pea de pelo corto, no emparentados. Los urolitos fueron analizados mediante microscopía estereoscópica, espectrosco- pía infrarroja y microscopía electrónica de barrido. Además de informar sobre estos casos clínicos, se hace una revisión detallada de la siopatología y de las recomendaciones actuales para el diagnóstico y manejo médico de esta patología.Se agradece al Consejo Nacional de Ciencia y Tecnolo- gía de México (CONACyT) y al Programa de Mejora- miento del Profesorado de la Secretaria de Educación Pública de México 2011 (PROMEP-SEP), el apoyo complementario para la realización de este trabajo

Validation of metabolic syndrome using medical records in the SUN cohort

The objective of this study was to evaluate the validity of self reported criteria of Metabolic Syndrome (MS) in the SUN (Seguimiento Universidad de Navarra) cohort using their medical records as the gold standard. METHODS: We selected 336 participants and we obtained MS related data according to Adult Treatment Panel III (ATP III) and International Diabetes Federation (IDF). Then we compared information on the self reported diagnosis of MS and MS diagnosed in their medical records. We calculated the proportion of confirmed MS, the proportion of confirmed non-MS and the intraclass correlation coefficients for each component of the MS. RESULTS: From those 336 selected participants, we obtained sufficient data in 172 participants to confirm or reject MS using ATP III criteria. The proportion of confirmed MS was 91.2% (95% CI: 80.7- 97.1) and the proportion of confirmed non-MS was 92.2% (95% CI: 85.7-96.4) using ATP III criteria. The proportion of confirmed MS using IDF criteria was 100% (95% CI: 87.2-100) and the proportion of confirmed non-MS was 97.1% (95% CI: 85.1-99.9). Kappa Index was 0.82 in the group diagnosed by ATP III criteria and 0.97 in the group diagnosed by IDF criteria. Intraclass correlation coefficients for the different component of MS were: 0.93 (IC 95%:0.91- 0.95) for BMI; 0.96 (IC 95%: 0.93-0.98) for waist circumference; 0.75 (IC 95%: 0.66-0.82) for fasting glucose; 0.50 (IC 95%:0.35-0.639) for HDL cholesterol; 0.78 (IC 95%: 0.70-0.84) for triglycerides; 0.49 (IC 95%:0.34-0.61) for systolic blood pressure and 0.55 (IC 95%: 0.41-0.65) for diastolic blood pressure. CONCLUSIONS: Self-reported MS based on self reported components of the SM in a Spanish cohort of university graduates was sufficiently valid as to be used in epidemiological studies