FDG PET and PET/CT: EANM procedure guidelines for tumour PET imaging: version 1.0

The aim of this guideline is to provide a minimum standard for the acquisition and interpretation of PET and PET/CT scans with [18F]-fluorodeoxyglucose (FDG). This guideline will therefore address general information about [18F]-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) and is provided to help the physician and physicist to assist to carrying out, interpret, and document quantitative FDG PET/CT examinations, but will concentrate on the optimisation of diagnostic quality and quantitative information

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Liability to alcohol dependence (AD) is heritable, but little is known about its complex polygenic architecture or its genetic relationship with other disorders. To discover loci associated with AD and characterize the relationship between AD and other psychiatric and behavioral outcomes, we carried out the largest genome-wide association study to date of DSM-IV-diagnosed AD. Genome-wide data on 14,904 individuals with AD and 37,944 controls from 28 case-control and family-based studies were meta-analyzed, stratified by genetic ancestry (European, n = 46,568; African, n = 6,280). Independent, genome-wide significant effects of different ADH1B variants were identified in European (rs1229984; P = 9.8 x 10(-13)) and African ancestries (rs2066702; P = 2.2 x 10(-9)). Significant genetic correlations were observed with 17 phenotypes, including schizophrenia, attention deficit-hyperactivity disorder, depression, and use of cigarettes and cannabis. The genetic underpinnings of AD only partially overlap with those for alcohol consumption, underscoring the genetic distinction between pathological and nonpathological drinking behaviors.Peer reviewe

FDG PET and PET/CT: EANM procedure guidelines for tumour PET imaging—version 1.0. Eur J Nucl Med Mol Imaging

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Personality and taxonomy preferences, and the influence of category choice on the user experience for music streaming services

Music streaming services increasingly incorporate different ways for users to browse for music. Next to the commonly used “genre” taxonomy, nowadays additional taxonomies, such as mood and activities, are often used. As additional taxonomies have shown to be able to distract the user in their search, we looked at how to predict taxonomy preferences in order to counteract this. Additionally, we looked at how the number of categories presented within a taxonomy influences the user experience. We conducted an online user study where participants interacted with an application called “Tune-A-Find”. We measured taxonomy choice (i.e., mood, activity, or genre), individual differences (e.g., personality traits and music expertise factors), and different user experience factors (i.e., choice difficulty and satisfaction, perceived system usefulness and quality) when presenting either 6- or 24-categories within the picked taxonomy. Among 297 participants, we found that personality traits are related to music taxonomy preferences. Furthermore, our findings show that the number of categories within a taxonomy influences the user experience in different ways and is moderated by music expertise. Our findings can support personalized user interfaces in music streaming services. By knowing the user’s personality and expertise, the user interface can adapt to the user’s preferred way of music browsing and thereby mitigate the problems that music listeners are facing while finding their way through the abundance of music choices online nowadays