Experimental calibration of flat jacks for in-situ testing of masonry

Flat-jack testing method is one of the most commonly used techniques for the structural assessment of existing masonry structures. Single and double flat jacks are usually adopted to evaluate the acting normal stress, or the compressive behaviour of masonry material. Test procedures are codified by international standards (e.g., A.S.T.M D4729-87; C1196-04; C1197-04, R.I.L.E.M TC 177–MDT D.4; R.I.L.E.M. TC 177–MDT D.5), which provide the preliminary calibration of an experimental coefficient (km) and of the effective area (Aeff), which determination influences significantly the reliability of the test. This article presents the result of an experimental study on the calibration of flat jacks for masonry testing. The problem is investigated by several tests carried out on two types of common flat jacks, which differ for geometry and producer. Two calibration methods are adopted in order to relate the pressure values of the flat jack with those of the hydraulic press and load cycles are performed in two different pressure ranges. Finally, a theoretical interpretation of results is made, which gives good predictions of calibration parameters. Results of this investigation highlight the influence of constructive features and service pressure of the jack adopted, for obtaining reliable results from the tests on masonry structures

Uno strumento di pianificazione per la salvaguardia degli edifici storico-monumentali. Un caso di studio: la chiesa del SS. Salvatore a Naro

Il patrimonio storico, e in particolare gli edifici monumentali, sono i manufatti tra i più vulnerabili nei confronti degli eventi sismici, e spesso determinano anche gravi ripercussioni su quello che comunemente è definito ”rischio urbano”. Per la conservazione e la tutela del patrimonio culturale nei riguardi dell’azione sismica è necessario disporre di strumenti di analisi in grado di permettere la valutazione della vulnerabilità e del rischio, nonché la progettazione degli interventi di miglioramento sismico. Le Linee Guida per la valutazione e riduzione del rischio sismico del patrimonio culturale – allineamento alle nuove Norme tecniche per le costruzioni, G.U. 26.02.2011, n°47 (di seguito indicate come Linee Guida) costituiscono strumento programmatico per la mitigazione del rischio sismico del patrimonio tutelato e strumento operativo per la valutazione quantitativa della sicurezza sismica di una costruzione storica in muratura, in condizioni ante e post intervento. Esse propongono un percorso della conoscenza del manufatto che restituisce un fattore di confidenza Fc in funzione del grado di approfondimento delle indagini e una successiva valutazione della vulnerabilità con una modellazione del comportamento strutturale individuata da tre diversi Livelli di Valutazione (LV1, LV2 LV3) di crescente completezza. L’articolo si propone di esaminare criticamente i metodi e gli strumenti proposti dalle Linee Guida attraverso l’applicazione ad un caso specifico del patrimonio storico - monumentale agrigentino: la chiesa del SS. Salvatore di Naro (v. Foto 1).The historical heritage, and in particular the monumental buildings, are among the most vulnerable artifacts against seismic events, and often also have serious repercussions on what is commonly defined as "urban risk". For the conservation and protection of cultural heritage with regard to seismic action, it is necessary to have analysis tools capable of allowing the assessment of vulnerability and risk, as well as the design of seismic improvement interventions. The Guidelines for the assessment and reduction of the seismic risk of cultural heritage - alignment with the new technical standards for buildings, G.U. 26.02.2011, n ° 47 (hereinafter referred to as Guidelines) constitute programmatic tool for the mitigation of the seismic risk of the protected heritage and operational tool for the quantitative assessment of the seismic safety of a historic masonry building, in pre and post intervention conditions. They propose a path of knowledge of the artifact that returns a confidence factor Fc according to the degree of depth of the investigations and a subsequent assessment of the vulnerability with a modeling of the structural behavior identified by three different Levels of Assessment (LV1, LV2 LV3) of increasing completeness. The article aims to critically examine the methods and tools proposed by the Guidelines through the application to a specific case of the historical-monumental heritage of Agrigento: the church of SS. Salvatore di Naro (see Photo 1)

Evaluation of Flat Jack Test Method Effectiveness for Masonry Structural Investigations

Flat jack testing method is one of the most commonly used techniques for the structural assessment of existing masonry structures. Single and double flat jack are commonly adopted to evaluate the acting normal stress, or the compressive behaviour of masonry material. Test procedures are codified by international standards (e.g. A.S.T.M D4729-87; C1196-04; C1197-04, R.I.L.E.M TC 177–MDT D.4; R.I.L.E.M. TC 177–MDT D.5), which provide the preliminary calibration of an experimental coefficient (km), which determination influences significantly the reliability of the test. This paper presents the result of an experimental study on the calibration of km coefficient for flat jacks. The problem is investigated by several tests carried out at DISMAT Laboratory in Canicattì (Italy). Different types of flat jacks made by different manufacturers are considered, and two calibration methods are adopted in order to relate the pressure values of the flat jack with those of the hydraulic press and obtaining the coefficient km. Results of this investigation highlighted the influence of materials used and production technology for the flat jacks for obtaining reliable results from the tests on masonry structures

Phylogenetic diversity and antimicrobial activities of bryozoan-associated bacteria isolated from Mediterranean and Baltic Sea habitats

To date, only a small number of investigations covering microbe–bryozoa associations have been carried out. Most of them have focused on a few bryozoan species and none have covered the antibacterial activities of associated bacteria. In the current study, the proportion and phylogenetic classification of Bryozoan-associated bacteria with antimicrobial properties were investigated. Twenty-one specimens of 14 different bryozoan species were collected from several sites in the Baltic and the Mediterranean Sea. A total of 340 associated bacteria were isolated, and 101 displayed antibiotic activities. While antibiosis was predominantly directed against Gram-positive test strains, 16S rRNA gene sequencing revealed affiliation of the isolates to Gram-negative classes (Flavobacteria, Alpha- and Gammaproteobacteria). One isolate was related to the Gram-positive Actinobacteria. The sequences were grouped into 27 phylotypes on the basis of similarity values ≥99.5%. A host-specific affiliation was not revealed as members of the same phylotype were derived from different bryozoan species. Site-specific patterns, however, were demonstrated. Strains of the genera Sphingomonas and Alteromonas were exclusively isolated from Mediterranean sites, whereas Shewanella, Marinomonas and Vibrio-related isolates were only from Baltic sites. Although Pseudoalteromonas affiliated strains were found in both habitats, they were separated into respective phylotypes. Isolates with 16S rDNA similarity values <98%, which could possibly represent new species, belonged to the genera Shewanella, Pseudoalteromonas and Tenacibaculum

"Delirium Day": A nationwide point prevalence study of delirium in older hospitalized patients using an easy standardized diagnostic tool

Background: To date, delirium prevalence in adult acute hospital populations has been estimated generally from pooled findings of single-center studies and/or among specific patient populations. Furthermore, the number of participants in these studies has not exceeded a few hundred. To overcome these limitations, we have determined, in a multicenter study, the prevalence of delirium over a single day among a large population of patients admitted to acute and rehabilitation hospital wards in Italy. Methods: This is a point prevalence study (called "Delirium Day") including 1867 older patients (aged 65 years or more) across 108 acute and 12 rehabilitation wards in Italian hospitals. Delirium was assessed on the same day in all patients using the 4AT, a validated and briefly administered tool which does not require training. We also collected data regarding motoric subtypes of delirium, functional and nutritional status, dementia, comorbidity, medications, feeding tubes, peripheral venous and urinary catheters, and physical restraints. Results: The mean sample age was 82.0 ± 7.5 years (58 % female). Overall, 429 patients (22.9 %) had delirium. Hypoactive was the commonest subtype (132/344 patients, 38.5 %), followed by mixed, hyperactive, and nonmotoric delirium. The prevalence was highest in Neurology (28.5 %) and Geriatrics (24.7 %), lowest in Rehabilitation (14.0 %), and intermediate in Orthopedic (20.6 %) and Internal Medicine wards (21.4 %). In a multivariable logistic regression, age (odds ratio [OR] 1.03, 95 % confidence interval [CI] 1.01-1.05), Activities of Daily Living dependence (OR 1.19, 95 % CI 1.12-1.27), dementia (OR 3.25, 95 % CI 2.41-4.38), malnutrition (OR 2.01, 95 % CI 1.29-3.14), and use of antipsychotics (OR 2.03, 95 % CI 1.45-2.82), feeding tubes (OR 2.51, 95 % CI 1.11-5.66), peripheral venous catheters (OR 1.41, 95 % CI 1.06-1.87), urinary catheters (OR 1.73, 95 % CI 1.30-2.29), and physical restraints (OR 1.84, 95 % CI 1.40-2.40) were associated with delirium. Admission to Neurology wards was also associated with delirium (OR 2.00, 95 % CI 1.29-3.14), while admission to other settings was not. Conclusions: Delirium occurred in more than one out of five patients in acute and rehabilitation hospital wards. Prevalence was highest in Neurology and lowest in Rehabilitation divisions. The "Delirium Day" project might become a useful method to assess delirium across hospital settings and a benchmarking platform for future surveys

Raccomandazioni cliniche in odontostomatologia

L’Organizzazione Mondiale della Sanità considera la salute orale come parte integrante, non solo dello stato di salute generale, ma anche della qualità della vita di ciascun individuo. In tale ottica, in accordo e con il sostegno del mondo professionale e della comunità scientifica di questo settore, le raccomandazioni cliniche in odontostomatologia contenute nel presente volume forniscono indicazioni e definiscono standard di intervento per la prevenzione e la cura delle più comuni patologie del cavo orale nonché per l’identificazione di percorsi terapeutici appropriati a supporto degli operatori pubblici e privati. Esse costituiscono, inoltre, uno strumento utile per mantenere alto il livello di qualità delle cure in questo periodo storico, nel quale, se da un lato crescono le opportunità tecniche di cura e la potenziale domanda delle stesse, dall’altro la riduzione delle risorse economiche a disposizione dei cittadini tende a limitare l’accesso all’offerta professionale privata e, al contempo, i processi di razionalizzazione dell’allocazione dei fondi nel SSN rendono più difficile l’accesso alle strutture pubbliche. L’individuazione di raccomandazioni cliniche chiaramente definite e rese pubbliche può facilitare la condivisione degli obiettivi e dei percorsi terapeutici tra odontoiatra e paziente, migliorare la comunicazione e, in ultima analisi, accrescere la fiducia sia nei riguardi del proprio specifico professionista che del “sistema delle cure” più in generale. La revisione delle “Raccomandazioni cliniche in odontostomatologia” si è resa necessaria in considerazione del cambiamento dell’evidenza scientifica, dell’immissione in commercio di nuovi materiali e dell’utilizzo di nuove tecnologie, specie in ambito protesico. Come per la precedente, alla realizzazione di questa edizione ha contribuito un ampio gruppo di docenti ed esperti delle singole branche odontoiatriche insieme alle più importanti e rappresentative Associazioni professionali e ai componenti della Commissione Albo Odontoiatri (CAO) nazionale

Diagnostic issues faced by a rare disease healthcare network during Covid-19 outbreak: data from the Campania Rare Disease Registry

Background: The aims of this study were: to investigate the capacity of the rare disease healthcare network in Campania to diagnose patients with rare diseases during the outbreak of Covid-19; and to shed light on problematic diagnoses during this period. Methods: To describe the impact of the Covid-19 pandemic on the diagnosis of patients with rare diseases, a retrospective analysis of the Campania Region Rare Disease Registry was performed. A tailored questionnaire was sent to rare disease experts to investigate major issues during the emergency period. Results: Prevalence of new diagnoses of rare disease in March and April 2020 was significantly lower than in 2019 (117 versus 317, P &lt; 0.001 and 37 versus 349, P &lt; 0.001, respectively) and 2018 (117 versus 389, P &lt; 0.001 and 37 versus 282, P &lt; 0.001, respectively). Eighty-two among 98 rare disease experts completed the questionnaire. Diagnostic success (95%), access to diagnosis (80%) and follow-up (72%), lack of Personal Protective Equipment (60%), lack of Covid-19 guidelines (50%) and the need for home therapy (78%) were the most important issues raised during Covid-19 outbreak. Conclusions: This study describes the effects of the Covid-19 outbreak on the diagnosis of rare disease in a single Italian region and investigates potential issues of diagnosis and management during this period

Diagnostic issues faced by a rare disease healthcare network during Covid-19 outbreak: data from the Campania Rare Disease Registry

Background: The aims of this study were: to investigate the capacity of the rare disease healthcare network in Campania to diagnose patients with rare diseases during the outbreak of Covid-19; and to shed light on problematic diagnoses during this period. Methods: To describe the impact of the Covid-19 pandemic on the diagnosis of patients with rare diseases, a retrospective analysis of the Campania Region Rare Disease Registry was performed. A tailored questionnaire was sent to rare disease experts to investigate major issues during the emergency period. Results: Prevalence of new diagnoses of rare disease in March and April 2020 was significantly lower than in 2019 (117 versus 317, P &lt; 0.001 and 37 versus 349, P &lt; 0.001, respectively) and 2018 (117 versus 389, P &lt; 0.001 and 37 versus 282, P &lt; 0.001, respectively). Eighty-two among 98 rare disease experts completed the questionnaire. Diagnostic success (95%), access to diagnosis (80%) and follow-up (72%), lack of Personal Protective Equipment (60%), lack of Covid-19 guidelines (50%) and the need for home therapy (78%) were the most important issues raised during Covid-19 outbreak. Conclusions: This study describes the effects of the Covid-19 outbreak on the diagnosis of rare disease in a single Italian region and investigates potential issues of diagnosis and management during this period