Polychromy of late gothic civil architecture: a world heritage monument case in Spain

[EN] The Silk Exchange of Valencia, Spain, is one of the best examples of late Gothic civil architecture in Europe, and was declared a World Heritage Monument by UNESCO in 1996. Prior to cleaning and conservation, technical examination identified the original pigments used to paint the walls, keys, vaults, arches and columns in the main hall, the Contract Hall. Cross sections of remnants of original colour (blue, green, red, gold, etc.) were investigated with optical microscopy, scanning electron microscopy with energy dispersive X-ray analysis, X-ray diffraction techniques and UV light. The study has revealed that the original paint today remains only in very limited areas. Evidence for a later maintenance operation of repainting was also found in the inscription that runs around the Contract Hall. The information has been very useful for deciding on the cleaning and conservation process.This work has been supported by Universidad Politécnica de Valencia’s Forum Unesco -University and Heritage and by Valencia City Council under the project: “Study and Diagnosis of Pathological Manifestations of the Stone and Project and Construction Management of Cleaning and Conservation of the Silk Exchange of Valencia "Ramirez, MJ.; Saiz Mauleón, MB.; Curiel-Esparza, J.; Llinares, J.; Soriano, M. (2013). Polychromy of late gothic civil architecture: a world heritage monument case in Spain. Mediterranean Archaeology and Archaeometry. 13(2):121-126. http://hdl.handle.net/10251/99866S12112613

The Variable Scale Evacuation Model (VSEM): a new tool for simulating massive evacuation processes during volcanic crises

Volcanic eruptions are among the most awesome and powerful displays of nature's force, constituting a major natural hazard for society (a single eruption can claim thousands of lives in an instant). Consequently, assessment and management of volcanic risk have become critically important goals of modern volcanology. Over recent years, numerous tools have been developed to evaluate volcanic risk and support volcanic crisis management: probabilistic analysis of future eruptions, hazard and risk maps, event trees, etc. However, there has been little improvement in the tools that may help Civil Defense officials to prepare Emergency Plans. Here we present a new tool for simulating massive evacuation processes during volcanic crisis: the Variable Scale Evacuation Model (VSEM). The main objective of the VSEM software is to optimize the evacuation process of Emergency Plans during volcanic crisis. For this, the VSEM allows the simulation of an evacuation considering different strategies depending on diverse impact scenarios. VSEM is able to calculate the required time for the complete evacuation taking into account diverse evacuation scenarios (number and type of population, infrastructure, road network, etc.) and to detect high-risk or "blackspots" of the road network. The program is versatile and can work at different scales, thus being capable of simulating the evacuation of small villages as well as huge cities

Effects on nodular extracts of Alnus glutinosa (l.) Gaertn. on ammonification, nitrification and CO2 production in different soils

The effect of root nodule extracts from European alder (Alnus glutinosa [L.] Gaertn.) on the rates of amrnonification, nitrification and C02 production was evaluated in three soils of different physico-chemical characteristics. The extracts decreased net ammonification rate (up to a 43% respect to water control), probably because of an increase of immobilization rather than an effect of a speciffc inhibitor. The rate of nitrification was increased by the extracts (up to 40% from water control) because of the ammonium present in the extracts. An increase in C02 production showed that the nodule extracts stimulate microbial activity. This depended not only on the amount of organic matter introduced by the extracts but also to some activator of microflora.Se evalúa el efecto de extractos nodulares del aliso europeo (Alnus glutinosa [L.] Gaertn.) sobre las tasas de amonificación, nitrificación y producción de C02 en tres suelos de características físico-químicas diferentes. Los extractos reducen la tasa de amonificación (un 43% menor que en el control con agua), probablemente debida a un aumento de la inmovilización más que a un inhibidor especifico. La tasa de nitrificación crece por efecto de los extractos (un 40% respecto al control con agua) a consecuencia del amonio presente en éstos. El incremento de la producción de C02 muestra que los extractos estimulan la actividad microbiana. Esto no parece depender sólo del aporte extra de materia orgánica por los extractos, sino por algún activador especifico

Rayleigh-wave attenuation by a semi-infinite two-dimensional elastic-band-gap crystal

In this paper, we report experiments on the scattering of surface-elastic waves by a periodic array of cylindrical holes. The experiments were performed in a marble quarry by drilling cylindrical holes in two different configurations: honeycomb and triangular lattices. The attenuation spectra of the surface waves show the existence of absolute band gaps for elastic waves in these semi-infinite two-dimensional crystals. Results are compared with theoretical calculations based on a scalar-wave approach. The scaling property of the underlying theory has led us to explore the possible application of the results obtained to the attenuation of surface waves in seismic movements.This work was partially supported by the Comisión Interministerial de Ciencia y Tecnología of Spain, Contract No. MAT97-0698-C04. We also thank the Consejo Superior de Investigaciones Científicas for the special funding to perform this experiment.Peer reviewe

Syphilis and HIV infection in indigenous Mbya Guarani communities of Puerto Iguazu (Argentina): diagnosis, contact tracking, and follow-up

The aim of study was to assess the prevalence of Treponema pallidum and HIV infection in Amerindian people (Mbya Guarani) over the age of 11 in Puerto Iguazu (Argentina) and to describe the contact tracking of cases. The method was a cross-sectional study in the Mbya Guarani people living in three villages of Puerto Iguazu (community A, pop. 1,146; community B, pop. 369; and community C, pop. 149). Participants were randomly invited to participate in the survey and in blood testing. Of the 551 participants, 48 were infected by T. pallidum (8.71%; 95% confidence interval [CI] 7.38-10.04). The infection prevalence decreased with age, standing at 9.66% in the 11-19 age group, 8.42% in 20-39 age group and 4.54% in people aged 40 and older. We tracked 130 contacts for the 48 T. pallidum cases; 39/40 (97.5%) sexual contacts tested positive for syphilis. Among the 90 children born to infected mothers, 76 aged 18 months or older tested negative, while 8/14 younger children were still at risk for congenital syphilis. There were four cases of HIV infection (0.72%, 95% CI 0.31-1.13). Prevalence of T. pallidum infection and HIV infection are relevant in this indigenous community of Argentina, representing a public health concern

An investigation into CLIL-related sections of EFL coursebooks : issues of CLIL inclusion in the publishing market

The current ELT global coursebook market has embraced CLIL as a weak form of bilingual education and an innovative component to include in General English coursebooks for EFL contexts. In this paper I investigate how CLIL is included in ELT coursebooks aimed at teenaged learners, available to teachers in Argentina. My study is based on the content analysis of four series which include a section advertised as CLIL-oriented. Results suggest that such sections are characterised by (1) little correlation between featured subject specific content and school curricula in L1, (2) oversimplification of contents, and (3) dominance of reading skills development and lower-order thinking tasks. Through this study, I argue that CLIL components become superficial supplements rather than a meaningful attempt to promote weak forms of bilingual education

Long-Term Optical Monitoring of Eta Carinae. Multiband light curves for a complete orbital period

The periodicity of 5.5 years for some observational events occurring in Eta Carinae manifests itself across a large wavelength range and has been associated with its binary nature. These events are supposed to occur when the binary components are close to periastron. To detect the previous periastron passage of Eta Car in 2003, we started an intensive, ground-based, optical, photometric observing campaign. We continued observing the object to monitor its photometric behavior and variability across the entire orbital cycle. Our observation program consisted of daily differential photometry from CCD images, which were acquired using a 0.8 m telescope and a standard BVRI filter set at La Plata Observatory. The photometry includes the central object and the surrounding Homunculus nebula. We present up-to-date results of our observing program, including homogeneous photometric data collected between 2003 and 2008. Our observations demonstrated that Eta Car has continued increasing in brightness at a constant rate since 1998. In 2006, it reached its brightest magnitude (V ~ 4.7) since about 1860s. The object then suddenly reverted its brightening trend, fading to V = 5.0 at the beginning of 2007, and has maintained a quite steady state since then. We continue the photometric monitoring of Eta Car in anticipation of the next "periastron passage", predicted to occur at the beginning of 2009.Comment: Accepted by A&A. The paper contains 3 figures and 2 table

Clinical relevance of monitoring serum levels of adalimumab in patients with rheumatoid arthritis in daily practice

[Objectives]: We aimed to assess the usefulness of measuring serum levels of adalimumab (ADL) and anti-ADL antibodies in 57 patients with rheumatoid arthritis (RA) treated with ADL for at least 3 months in daily practice. [Methods]: All patients received concomitant disease-modifying anti-rheumatic drug (DMARD). Receiver-operator characteristics (ROC) analysis was used to obtain the cut-off value of ADL for low disease activity (DAS28-ESR ≤3.2). [Results]: Anti-ADL antibodies were detected in 4 (7%) patients with a mean (SD) DAS28 score of 4.6 (0.9). Patients with positive anti-ADL antibodies had significantly lower levels of ADL and higher DAS28 scores than those with negative antibodies. Patients with DAS28 ≤3.2 as compared with patients with DAS28 >3.2 showed significantly better SDAI score, higher serum concentrations of ADL and none of them showed anti-ADL antibodies. The cut-off of serum level of ADL for DAS28 11.3 mg/L. Patients in the medium group were closed to clinical remission (median DAS28 2.7) and patients in the high group were on clinical remission (DAS28 2.1). [Conclusion]: Serum levels of ADL should be maintained >4.3 mg/L. In patients with ADL levels >11.3 mg/L, a decrease of the dose of ADL or an increase in the interval between doses may be planned. The presence of anti-ADL antibodies was associated with a loss of clinical efficacy of ADL.Peer Reviewe

The PRIDE database and related tools and resources in 2019: improving support for quantification data

The PRoteomics IDEntifications (PRIDE) database (https://www.ebi.ac.uk/pride/) is the world's largest data repository of mass spectrometry-based proteomics data, and is one of the founding members of the global ProteomeXchange (PX) consortium. In this manuscript, we summarize the developments in PRIDE resources and related tools since the previous update manuscript was published in Nucleic Acids Research in 2016. In the last 3years, public data sharing through PRIDE (as part of PX) has definitely become the norm in the field. In parallel, data re-use of public proteomics data has increased enormously, with multiple applications. We first describe the new architecture of PRIDE Archive, the archival component of PRIDE. PRIDE Archive and the related data submission framework have been further developed to support the increase in submitted data volumes and additional data types. A new scalable and fault tolerant storage backend, Application Programming Interface and web interface have been implemented, as a part of an ongoing process. Additionally, we emphasize the improved support for quantitative proteomics data through the mzTab format. At last, we outline key statistics on the current data contents and volume of downloads, and how PRIDE data are starting to be disseminated to added-value resources including Ensembl, UniProt and Expression Atlas