5,378 research outputs found
A multinuclear 1H, 13C and 11B solid-state MAS NMR study of 16- and 18-electron organometallic ruthenium and osmium carborane complexes
YesThe first 1H, 13C, 31P and 11B solid state MAS NMR studies of electron-
deficient carborane-containing ruthenium and osmium
complexes [Ru/Os(p-cym)(1,2-dicarba-closo-dodecaborane-1,2-
dithiolate)] are reported. The MAS NMR data from these 16-electron
complexes are compared to those of free carborane-ligand
and an 18-electron triphenylphosphine ruthenium adduct, and
reveal clear spectral differences between 16- and 18-electron
organometallic carborane systems in the solid state.We thank the Swiss National Science Foundation (grant no. PA00P2-145308 to NPEB), the ERC (grant no. 247450 to PJS), EPSRC (grant no. EP/F034210/1) and EC COST Action CM1105 for support. JVH thanks EPSRC and the University of Warwick for partial funding of the solid state NMR infrastructure at Warwick, and acknowledges additional support obtained through Birmingham Science City: Innovative Uses for Advanced Materials in the Modern World (West Midlands Centre for Advanced Materials Project 2), with support from Advantage West Midlands (AWM) and partial funding by the European Regional Development Fund (ERDF)
Diabetes-induced alterations in urothelium function:Enhanced ATP release and nerve-evoked contractions in the streptozotocin rat bladder
A Modular Bio-inspired Robotic Hand with High Sensitivity
While parallel grippers and multi-fingered robotic hands are well developed
and commonly used in structured settings, it remains a challenge in robotics to
design a highly articulated robotic hand that can be comparable to human hands
to handle various daily manipulation and grasping tasks. Dexterity usually
requires more actuators but also leads to a more sophisticated mechanism design
and is more expensive to fabricate and maintain. Soft materials are able to
provide compliance and safety when interacting with the physical world but are
hard to model. This work presents a hybrid bio-inspired robotic hand that
combines soft matters and rigid elements. Sensing is integrated into the rigid
bodies resulting in a simple way for pose estimation with high sensitivity. The
proposed hand is in a modular structure allowing for rapid fabrication and
programming. The fabrication process is carefully designed so that a full hand
can be made with low-cost materials and assembled in an efficient manner. We
demonstrate the dexterity of the hand by successfully performing human grasp
types.Comment: 7 pages, 13 figures, IEEE RoboSoft 202
Haemogenic endocardium contributes to transient definitive haematopoiesis.
Haematopoietic cells arise from spatiotemporally restricted domains in the developing embryo. Although studies of non-mammalian animal and in vitro embryonic stem cell models suggest a close relationship among cardiac, endocardial and haematopoietic lineages, it remains unknown whether the mammalian heart tube serves as a haemogenic organ akin to the dorsal aorta. Here we examine the haemogenic activity of the developing endocardium. Mouse heart explants generate myeloid and erythroid colonies in the absence of circulation. Haemogenic activity arises from a subset of endocardial cells in the outflow cushion and atria earlier than in the aorta-gonad-mesonephros region, and is transient and definitive in nature. Interestingly, key cardiac transcription factors, Nkx2-5 and Isl1, are expressed in and required for the haemogenic population of the endocardium. Together, these data suggest that a subset of endocardial/endothelial cells serve as a de novo source for transient definitive haematopoietic progenitors
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