Treatment Retention Strategies in Transition Age Youth

This study tests Motivational Interviewing as a treatment retention intervention in transition age youth to determine whether sufficient evidence can be found to justify a full scale clinical trial

Disparities in Child and Adolescent Psychoactive Medication Prescription Practices by Race and Ethnicity

Key Points: (1) Compared to their non-Latino white counterparts, children and adolescents from racial-ethnic minority groups in the U.S. are less likely to receive prescriptions for psychoactive medication; (2) Racial-ethnic minority children and adolescents are also significantly less likely to receive mental health care; (3) Controlling for access to mental health care and for geographic variation reduces but does not eliminate variations in psychoactive prescriptions by race and ethnicity; (4) Controlling for mental health need and level of impairment does not eliminate variations in psychoactive prescriptions by race and ethnicity; (5) Reducing disparities will require coordinated efforts to educate families and providers, promotion of evidence-based practices, steps to overcome geographic and language barriers, and additional research for understanding the underlying reasons for variations in prescription patterns

Multicultural Academic Interest Group: Promoting Multicultural Research, Education & Services

Eliminating racial/ethnic disparities in access and quality of mental care has emerged as a national priority as highlighted in the 2001 Surgeon General’s report, the President’s New Freedom Commission on Mental Health, and Healthy People 2000 and 2010. The National Institutes of Health (NIH) ranks this issue third among its top five priorities

Lifetime Alcohol Abuse Prevalence: Role of Childhood and Adult Religion

Findings presented regarding childhood and adult religiosity/spirituality as protective factors against Lifetime Alcohol Abuse

Distal and Proximal Religiosity as Protective Factors for Adolescent and Emerging Adult Alcohol Use

Data from emerging adults (ages 18-29, N = 900) in the National Comorbidity Survey Replication Study was used to examine the influence of childhood and emerging adult religiosity and religious-based decision-making, and childhood adversity, on alcohol use. Childhood religiosity was protective against early alcohol use and progression to later abuse or dependence, but did not significantly offset the influence of childhood adversity on early patterns of heavy drinking in adjusted logistic regression models. Religiosity in emerging adulthood was negatively associated with alcohol use disorders. Protective associations for religiosity varied by gender, ethnicity and childhood adversity histories. Higher religiosity may be protective against early onset alcohol use and later development of alcohol problems, thus, should be considered in prevention programming for youth, particularly in faith-based settings. Mental health providers should allow for integration of clients\u27 religiosity and spirituality beliefs and practices in treatment settings if clients indicate such interest

Pengaruh Jenis Media Tanam dan Interval Pemberian Pupuk Daun Terhadap Pertumbuhan Plantlet Anggrek Dendrobium Blue Twist x Dendrobium Biggibum pada Tahap Aklimatisasi dan Pembesaran

Dendrobium orchids have the potential to be developed because they have a variety of types, shapes and sizes. The choice of planting media and fertilization is an important factor in the success of orchid propagation, especially at the acclimatization stage. The aim of this research were determine the type of planting media and the best interval for giving foliar fertilizer and determine the best interactions and combinations of treatment of the type of planting media and the interval for giving foliar fertilizer on the growth of dendrobium orchid plantlets in the acclimatization and enlargement stages. This research used a factorial Randomized Block Design (RAK) with the first factor being the type of planting media and the second factor being the interval of foliar fertilizer application. The first factor includes M1: wood charcoal, M2: cocopeat, M3: wood charcoal + cocopeat 1:1, M4: wood charcoal + cocopeat 1:2, and M5: wood charcoal + cocopeat 1:3. The second factor includes P1: once every 4 days, P2: once every 8 days, P3: once every 12 days. The results of the research showed that the cocopeat planting media type provided the best percentage of acclimatization success for the Dendrobium Blue twist x Dendrobium Biggibum orchids. Providing foliar fertilizer at 8-day intervals provides the best increase in plantlet height and leaf width at the acclimatization and plantlet enlargement stages of Dendrobium Blue twist x Dendrobium bigibbum orchids. There was no interaction between the use of planting media type and the interval of foliar fertilizer application

Review: Laboratorium Virtual untuk Pembelajaran Kimia di Era Digital

Pesatnya perkembangan teknologi informasi di era digital harus dimanfaatkan secara optimal untuk meningkatkan kualitas pembelajaran kimia. Di era digital ini, penggunaan laboratorium virtual dapat menggantikan laboratorium nyata sebagai sarana untuk membuktikan teori, hukum, dan konsep kimia. Kajian ini menelaah berbagai platform laboratorium virtual yang dapat digunakan dalam pembelajaran kimia. Platform laboratorium virtual yang dikaji dalam artikel ini adalah Chemcollective, Laboratorium Maya, PhET, dan Olabs. Setiap platform laboratorium virtual yang dikaji memiliki kelebihan dan kekurangan, sehingga informasi ini diharapkan dapat menjadi bahan pertimbangan bagi guru dalam memilih platform laboratorium virtual yang sesuai dengan tujuan pembelajaran kimia yang telah dirancang

DTU Synthetic Promoter Library Standard

The purpose of this RFC is to outline a method for generating a BioBrick compatible Synthetic Promoter Library (SPL) within bacteria in order to fine-tune the expression of BioBrick parts and devices

Evaluation of the integrated intervention for dual problems and early action among latino immigrants with co-occurring mental health and substance misuse symptoms: A randomized clinical trial

Importance: Immigrants are at an increased risk for co-occurring mental health and substance misuse symptoms; however, effective treatments are lacking. Objective: To evaluate the effectiveness of the Integrated Intervention for Dual Problems and Early Action (IIDEA) program compared with enhanced usual care. Design, Setting, and Participants: This effectiveness randomized clinical trial was conducted from September 2, 2014, to February 2, 2017, in 17 clinics or emergency departments and 24 community sites in Boston, Massachusetts, as well as in Madrid and Barcelona, Spain. Equal randomization (1:1) in 2-person blocks was used, assigning participants to either the IIDEA treatment group (n = 172) or the enhanced usual care control group (n = 169). Intent-to-treat analyses assessed effectiveness, and post hoc analyses examined whether results varied by symptom severity or treatment dose. Eligible participants were between 18 and 70 years of age, self-identified as Latino, screened positive for co-occurring symptoms, and were not receiving specialty behavioral health services. Interventions: Participants were randomized to a 10-session IIDEA treatment or to enhanced usual care. Main Outcomes and Measures: Primary outcomes were changes in alcohol and drug misuse and results of a urine test for drug metabolites but not for alcohol misuse. Secondary outcomes were symptoms of depression, generalized anxiety, posttraumatic stress disorder, and overall mental health. Results: In total, 341 participants were randomized to either the IIDEA treatment group (n = 172; 94 [54.7%] female, mean [SD] age, 33.5 [11.6] years) or the enhanced usual care control group (n = 169; 80 [47.3%] female, mean [SD] age, 34.3 [11.8] years). No statistically significant effects of IIDEA were found for primary drug and alcohol outcomes (ASI Lite-drug score: β = -0.02 [SE, 0.69; P = .88; Cohen d, 0.00; 95% CI, -0.17 to 0.17]; ASI Lite-alcohol score: β = -0.01 [SE, 1.19; P = .66; Cohen d, 0.00; 95% CI, -0.12 to 0.12]; urine drug test result: β = -0.36 [SE, 0.43; P = .50; OR, 0.70; 95% CI, 0.30-1.61]), but statistically significant effects were observed for secondary mental health outcomes. The IIDEA treatment was effective in reducing depressive symptoms per the Public Health Questionnaire-9 score (β = -1.14; SE, 0.47; P = .02; Cohen d, 0.20 [95% CI, 0.04-0.36]), posttraumatic stress disorder symptoms per the Posttraumatic Stress Disorder Checklist-5 score (β = -3.23; SE, 1.59; P = .04; Cohen d, 0.25 [95% CI, 0.01-0.37]), and overall mental health symptoms per the Hopkins Symptom Checklist-20 (β = -0.20; SE, 0.07; P = .01; Cohen d, 0.25 [95% CI, 0.08-0.42]) and composite mental health (β = -3.70; SE, 1.75; P = .04; Cohen d, 0.19 [95% CI, 0.01-0.36]) scores at the 6-month follow-up. Exploratory analyses suggested that 6-month treatment effects occurred for patients whose drug misuse was moderate to severe at the baseline assessment. Among patients with moderate to severe substance misuse, IIDEA substantially reduced substance use per the urine test results (odds ratio, 0.25 [95% CI, 0.09-0.67]; P = .01). Treatment dose showed small to large effect sizes by outcome. Conclusions and Relevance: The IIDEA treatment did not change drug misuse but did improve secondary mental health and substance misuse outcomes for a heterogeneous population with moderate to severe symptoms; this finding provides a path for treating Latino immigrants with co-occurring mental health and substance misuse symptoms. Trial Registration: ClinicalTrials.gov Identifier: NCT02038855.This study was funded in part by grant R01DA034952 from NIDA of the National Institutes of Health; grant R01MH100155-01S1 from NIMH; and grants ISCII PI13/02200 and PI16/01852 from Instituto de Salud Carlos III, grant 20151073 from Delegación del Gobierno para el Plan Nacional de Drogas, and grant LSRG-1-005-16 from the American Foundation for Suicide Prevention (Dr Baca-García

Imported arboviral infections in Italy, July 2014-October 2015: A National Reference Laboratory report

BACKGROUND: Imported cases of infections due to Dengue (DENV) and Chikungunya (CHIKV) viruses and, more recently, Zika virus (ZIKV) are commonly reported among travelers returning from endemic regions. In areas where potentially competent vectors are present, the risk of autochthonous transmission of these vector-borne pathogens is relatively high. Laboratory surveillance is crucial to rapidly detect imported cases in order to reduce the risk of transmission. This study describes the laboratory activity performed by the National Reference Laboratory for Arboviruses (NRLA) at the Italian National Institute of Health in the period from July 2014 to October 2015. METHODS: Samples from 180 patients visited/hospitalized with a suspected DENV/CHIKV/ZIKV infection were sent to the NRLA from several Italian Hospitals and from Regional Reference Laboratories for Arboviruses, in agreement with the National Plan on human surveillance of vector-borne diseases. Both serological (ELISA IgM test and Plaque Reduction Neutralization Test-PRNT) and molecular assays (Real Time PCR tests, RT-PCR plus nested PCR and sequencing of positive samples) were performed. RESULTS: DENV infection was the most frequently diagnosed (80 confirmed/probable cases), and all four genotypes were detected. However, an increase in imported CHIKV cases (41 confirmed/probable cases) was observed, along with the detection of the first ZIKV cases (4 confirmed cases), as a consequence of the recent spread of both CHIKV and ZIKV in the Americas. CONCLUSIONS: Main diagnostic issues highlighted in our study are sensitivity limitations of molecular tests, and the importance of PRNT to confirm serological results for differential diagnosis of Arboviruses. The continuous evaluation of diagnostic strategy, and the implementation of laboratories networks involved in surveillance activities is essential to ensure correct diagnosis, and to improve the preparedness for a rapid and proper identification of viral threats