Written information about individual medicines for consumers.

Medicines are the most common intervention in most health services. As with all treatments, those taking medicines need sufficient information: to enable them to take and use the medicines effectively, to understand the potential harms and benefits, and to allow them to make an informed decision about taking them. Written medicines information, such as a leaflet or provided via the Internet, is an intervention that may meet these purposes

L'immobilisation de cellules de mammiferes en gel d'alginate: aspects techniques et cellulaires. Perspectives biotechnologiques

SIGLEINIST T 71177 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc

Interspecies comparison of phagolysosomal ph in alveolar macrophages.

Differences in the translocation of dissolved particle mass from the lungs to the blood were found in a recent large interspecies comparison of long-term lung clearance after inhalation of uniform 57Co3O4 particles. Since the particles were dissolved most prominently in phagolysosornes of alveolar macrophages, the differences may have been due to differences in pH in these vacuoles. The phagolysosomal pH was measured in alveolar macrophages obtained by bronchoalveolar lavage from baboons, dogs, guinea pigs, and rabbits using fluorescein-labeled amorphous silica particles as a probe. In the alveolar macrophages from the 4 species pH was on average 4.8 or 4.9 with small variations among and within animals. The results indicate that it is unlikely that differences in phagolysosomal pH are responsible for the differences in translocation observed previously

Un outil pédagogique en dosimétrie interne sous forme d'un cédérom : CALLIOPE

“ CALLIOPE " est une base de données sous forme de cédérom destinée à la formation de la dosimétrie interne. Cet outil est une aide pour l'interprétation des mesures de surveillance des travailleurs ou du poste de travail réalisées en routine ou après incident. Il contient des informations issues des sept principales Publications de la CIPR sur la dosimétrie interne et permet l'accès aux données nucléaires du logiciel NUCLEIDE. Cet utilitaire facilite la mise en application des réglementations extraites de la Directive européenne 96/29 dans le respect des nouvelles limites. Il est une aide à la validation par l'utilisateur des démarches et des estimations des doses consécutives à l'exposition interne