1,640 research outputs found

    Positional information readout in Ca2+Ca^{2+} signaling

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    Living cells respond to spatial signals. Signal transmission to the cell interior often involves the release of second messengers like Ca2+Ca^{2+} . They will eventually trigger a physiological response by activating kinases that in turn activate target proteins through phosphorylation. Here, we investigate theoretically how positional information can be accurately read out by protein phosphorylation in spite of rapid second messenger diffusion. We find that accuracy is increased by binding of the kinases to the cell membrane prior to phosphorylation and by increasing the rate of Ca2+Ca^{2+} loss from the cell interior. These findings could explain some salient features of conventional protein kinases C

    Symposium 9: Ecology, Brain and Behaviour

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    Safe-arm slide ejection effect on grenade trajectory

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    This memorandum reports the effect of the safe-arm slide ejection on the grenade range. The report also suggests a method by which the range may be computed by any interested party which includes the safe-arm slide ejection corrections.prepared by R. Lipp, P. Ireton

    Examination of Affective Responses to Images in Sponsorship-Linked Marketing

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    Sponsorship of sports, arts, charity and entertainment events are all viewed as capable in building corporate and brand image. In this process, visual images are a key vehicle in the transportation of affect from an event to a brand. While the overall positive feeling of a sponsored event or activity is argued to rub-off on a brand, we know less about how individual images function in this process and we know even less about the role of negative images. Here, three experiments consider the potential of affect transfer from images to brands. All three experiments show explicit transfer of affect, and one finds implicit evaluative change. Importantly, positive images when mixed with negative are off-setting. This research suggests that when negative events occur and are captured and repeated in the media, practitioners able to supply positive images may be able to control negative affective responses to some degree

    Flechsig's rule and quantitative behavior genetics

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    Comment on ``Reduction of static field equation of Faddeev model to first order PDE'', arXiv:0707.2207

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    The authors of the article Phys. Lett. B 652 (2007) 384, (arXiv:0707.2207), propose an interesting method to solve the Faddeev model by reducing it to a set of first order PDEs. They first construct a vectorial quantity α\bm \alpha , depending on the original field and its first derivatives, in terms of which the field equations reduce to a linear first order equation. Then they find vectors α1\bm \alpha_1 and α2\bm \alpha_2 which identically obey this linear first order equation. The last step consists in the identification of the αi\bm \alpha_i with the original α\bm \alpha as a function of the original field. Unfortunately, the derivation of this last step in the paper cited above contains an error which invalidates most of its results
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