RRI as a governance paradigm: What is new?

This chapter frames RRI as an emerging governance approach in the EU regulatory context. We argue that reference to fundamental rights makes RRI a distinctive approach to responsibility compared to other existing paradigms and that human rights, in particular those laid down in the Charter of Fundamental Rights of the European Union, are not necessarily a constraint but can instead be a catalyst of innovation. Eventually we maintain that a governance framework based on the complementarity between legal norms and voluntary commitments might successfully combine the respect of fundamental rights with the openness and flexibility of the innovation process

Brain temperature regulation in poor-grade subarachnoid hemorrhage patients – A multimodal neuromonitoring study

Elevated body temperature (Tcore) is associated with poor outcome after subarachnoid hemorrhage (SAH). Brain temperature (Tbrain) is usually higher than Tcore. However, the implication of this difference (Tdelta) remains unclear. We aimed to study factors associated with higher Tdelta and its association with outcome. We included 46 SAH patients undergoing multimodal neuromonitoring, for a total of 7879 h of averaged data of Tcore, Tbrain, cerebral blood flow, cerebral perfusion pressure, intracranial pressure and cerebral metabolism (CMD). Three-months good functional outcome was defined as modified Rankin Scale ≤2. Tbrain was tightly correlated with Tcore (r = 0.948, p < 0.01), and was higher in 73.7% of neuromonitoring time (Tdelta +0.18°C, IQR −0.01 – 0.37°C). A higher Tdelta was associated with better metabolic state, indicated by lower CMD-glutamate ( p = 0.003) and CMD-lactate ( p < 0.001), and lower risk of mitochondrial dysfunction (MD) (OR = 0.2, p < 0.001). During MD, Tdelta was significantly lower (0°C, IQR −0.2 – 0.1; p < 0.001). A higher Tdelta was associated with improved outcome (OR = 7.7, p = 0.002). Our study suggests that Tbrain is associated with brain metabolic activity and exceeds Tcore when mitochondrial function is preserved. Further studies are needed to understand how Tdelta may serve as a surrogate marker for brain function and predict clinical course and outcome after SAH

Europe's plans for responsible science

In the past, European framework programs for research and innovation have included funding for the integration of science and society (1). Collaborative projects have brought together diverse sets of actors to co-create and implement common agendas through citizen science, science communication, public engagement, and responsible research and innovation (RRI) and have built an evidence base about science-society interaction (2, 3). In the proposal for the upcoming Horizon Europe program, however, there is no sustained support for RRI, nor is there a program line dedicated to co-creating knowledge and agendas with civil society (4). These serious oversights must be corrected before the Horizon Europe program is adopted by the Council and the European Parliament

Joint declaration on mainstreaming RRI across Horizon Europe

Leading RRI researchers and practitioners, together with policymakers and stakeholder organisations, discussed the state-of-the-art and future perspectives for RRI at the ‘Pathways to Transformation’ conference in June 2019, an event which was extended beyond Brussels, for instance by ca. 330 original tweets and ca. 840 retweets from ca. 160 unique accounts. In the conference, many participants expressed their concern about an uncertain future for RRI in the EC. As a result, numerous large-scale EU-funded RRI projects signed a Joint Declaration, urging the European Commission to make RRI a key objective of the upcoming framework programme, Horizon Europe – a plea to both mainstream the approach across the programme and provide specific resources for strengthening the RRI knowledge base. As the Horizon Europe programme is being forged, it is timely to present the Declaration for a broader audience

Improve Alignment of Research Policy and Societal Values

Historically, scientific and engineering expertise has been key in shaping research and innovation (R&I) policies, with benefits presumed to accrue to society more broadly over time (1). But there is persistent and growing concern about whether and how ethical and societal values are integrated into R&I policies and governance, as we confront public disbelief in science and political suspicion toward evidence-based policy-making (2). Erosion of such a social contract with science limits the ability of democratic societies to deal with challenges presented by new, disruptive technologies, such as synthetic biology, nanotechnology, genetic engineering, automation and robotics, and artificial intelligence. Many policy efforts have emerged in response to such concerns, one prominent example being Europe's Eighth Framework Programme, Horizon 2020 (H2020), whose focus on “Responsible Research and Innovation” (RRI) provides a case study for the translation of such normative perspectives into concrete policy action and implementation. Our analysis of this H2020 RRI approach suggests a lack of consistent integration of elements such as ethics, open access, open innovation, and public engagement. On the basis of our evaluation, we suggest possible pathways for strengthening efforts to deliver R&I policies that deepen mutually beneficial science and society relationships.Horizon 2020(H2020)741402Merit, Expertise and Measuremen

Senado aprova projeto para coibir supersalários

Vencimentos. Proposta que regulamenta teto constitucional é vista por entidades de magistrados como mais uma ofensiva de Renan Calheiros contra o Poder Judiciári

Temer abriga aliados de Cunha no planalto

Um ex-advogado e um ex-assessor do peemedebista, afastado do comando da Câmara, são nomeados para postos estratégicos na Casa Civil e na Secretaria de Govern

Monitoring the Evolution and Benefits of Responsible Research and Innovation (MoRRI). Presentations MoRRI final event (D15). PART 1. Day 2 - Discussions on policy aspects: Presentation held at Final event - Discussion on policy aspects. Date: 7 March 2018. Location: Fondation Universitaire – rue d’Egmont 11, Brussels

This presentation was delivered at the final event of the MoRRI project during the discussions on policy aspects. The main objective of the event was to disseminate the findings of the MoRRI study. The event had, as input, a public access version of the final draft of the study report (D11). This deliverable was circulated beforehand to the participants invited to the public event. The public event offered the opportunity to discuss and validate this deliverable in a joint exercise. This exercise sought to obtain the necessary buy in from key stakeholders regarding the monitoring system and to obtain information on those aspects that can be improved. A series of participatory workshops allowed the participants representing the different stakeholder groups to comment on specific aspects related to future policy actions. This is part 1 (of 3) of the presentation delivered during this final event. There are two sections: Responsible Research and Innovation (RRI) in the making: the researchers’ perspective, Ralf Lindner; Impacts of RRI: Findings from case study programme, Erich Griessler