482 research outputs found
Homophily-based social group formation in a spin-glass self-assembly framework
Homophily, the tendency of humans to attract each other when sharing similar
features, traits, or opinions has been identified as one of the main driving
forces behind the formation of structured societies. Here we ask to what extent
homophily can explain the formation of social groups, particularly their size
distribution. We propose a spin-glass-inspired framework of self-assembly,
where opinions are represented as multidimensional spins that dynamically
self-assemble into groups; individuals within a group tend to share similar
opinions (intra-group homophily), and opinions between individuals belonging to
different groups tend to be different (inter-group heterophily). We compute the
associated non-trivial phase diagram by solving a self-consistency equation for
'magnetization' (combined average opinion). Below a critical temperature, there
exist two stable phases: one ordered with non-zero magnetization and large
clusters, the other disordered with zero magnetization and no clusters. The
system exhibits a first-order transition to the disordered phase. We
analytically derive the group-size distribution that successfully matches
empirical group-size distributions from online communities.Comment: 6 pages, 5 pages of SI, to appear in Phys. Rev. Let
System size resonance in coupled noisy systems and in the Ising model
We consider an ensemble of coupled nonlinear noisy oscillators demonstrating
in the thermodynamic limit an Ising-type transition. In the ordered phase and
for finite ensembles stochastic flips of the mean field are observed with the
rate depending on the ensemble size. When a small periodic force acts on the
ensemble, the linear response of the system has a maximum at a certain system
size, similar to the stochastic resonance phenomenon. We demonstrate this
effect of system size resonance for different types of noisy oscillators and
for different ensembles -- lattices with nearest neighbors coupling and
globally coupled populations. The Ising model is also shown to demonstrate the
system size resonance.Comment: 4 page
Experimental evidence of stochastic resonance without tuning due to non Gaussian noises
In order to test theoretical predictions, we have studied the phenomenon of
stochastic resonance in an electronic experimental system driven by white non
Gaussian noise. In agreement with the theoretical predictions our main findings
are: an enhancement of the sensibility of the system together with a remarkable
widening of the response (robustness). This implies that even a single resonant
unit can reach a marked reduction in the need of noise tuning.Comment: 4 pages, 3 figure
An air-stable DPP-thieno-TTF copolymer for single-material solar cell devices and field effect transistors
Following an approach developed in our group to incorporate tetrathiafulvalene (TTF) units into conjugated polymeric systems, we have studied a low band gap polymer incorporating TTF as a donor component. This polymer is based on a fused thieno-TTF unit that enables the direct incorporation of the TTF unit into the polymer, and a second comonomer based on the diketopyrrolopyrrole (DPP) molecule. These units represent a donor–acceptor copolymer system, p(DPP-TTF), showing strong absorption in the UV–visible region of the spectrum. An optimized p(DPP-TTF) polymer organic field effect transistor and a single material organic solar cell device showed excellent performance with a hole mobility of up to 5.3 × 10–2 cm2/(V s) and a power conversion efficiency (PCE) of 0.3%, respectively. Bulk heterojunction organic photovoltaic devices of p(DPP-TTF) blended with phenyl-C71-butyric acid methyl ester (PC71BM) exhibited a PCE of 1.8%
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate structural breakdown. Such an unavoidable variant of cellular demise is generally referred to as ‘accidental cell death’ (ACD). In most settings, however, cell death is initiated by a genetically encoded apparatus, correlating with the fact that its course can be altered by pharmacologic or genetic interventions. ‘Regulated cell death’ (RCD) can occur as part of physiologic programs or can be activated once adaptive responses to perturbations of the extracellular or intracellular microenvironment fail. The biochemical phenomena that accompany RCD may be harnessed to classify it into a few subtypes, which often (but not always) exhibit stereotyped morphologic features. Nonetheless, efficiently inhibiting the processes that are commonly thought to cause RCD, such as the activation of executioner caspases in the course of apoptosis, does not exert true cytoprotective effects in the mammalian system, but simply alters the kinetics of cellular demise as it shifts its morphologic and biochemical correlates. Conversely, bona fide cytoprotection can be achieved by inhibiting the transduction of lethal signals in the early phases of the process, when adaptive responses are still operational. Thus, the mechanisms that truly execute RCD may be less understood, less inhibitable and perhaps more homogeneous than previously thought. Here, the Nomenclature Committee on Cell Death formulates a set of recommendations to help scientists and researchers to discriminate between essential and accessory aspects of cell death
Tidying Up International Nucleotide Sequence Databases: Ecological, Geographical and Sequence Quality Annotation of ITS Sequences of Mycorrhizal Fungi
Sequence analysis of the ribosomal RNA operon, particularly the internal transcribed spacer (ITS) region, provides a powerful tool for identification of mycorrhizal fungi. The sequence data deposited in the International Nucleotide Sequence Databases (INSD) are, however, unfiltered for quality and are often poorly annotated with metadata. To detect chimeric and low-quality sequences and assign the ectomycorrhizal fungi to phylogenetic lineages, fungal ITS sequences were downloaded from INSD, aligned within family-level groups, and examined through phylogenetic analyses and BLAST searches. By combining the fungal sequence database UNITE and the annotation and search tool PlutoF, we also added metadata from the literature to these accessions. Altogether 35,632 sequences belonged to mycorrhizal fungi or originated from ericoid and orchid mycorrhizal roots. Of these sequences, 677 were considered chimeric and 2,174 of low read quality. Information detailing country of collection, geographical coordinates, interacting taxon and isolation source were supplemented to cover 78.0%, 33.0%, 41.7% and 96.4% of the sequences, respectively. These annotated sequences are publicly available via UNITE (http://unite.ut.ee/) for downstream biogeographic, ecological and taxonomic analyses. In European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena/), the annotated sequences have a special link-out to UNITE. We intend to expand the data annotation to additional genes and all taxonomic groups and functional guilds of fungi
Factors That Affect Large Subunit Ribosomal DNA Amplicon Sequencing Studies of Fungal Communities: Classification Method, Primer Choice, and Error
Nuclear large subunit ribosomal DNA is widely used in fungal phylogenetics and to an increasing extent also amplicon-based environmental sequencing. The relatively short reads produced by next-generation sequencing, however, makes primer choice and sequence error important variables for obtaining accurate taxonomic classifications. In this simulation study we tested the performance of three classification methods: 1) a similarity-based method (BLAST + Metagenomic Analyzer, MEGAN); 2) a composition-based method (Ribosomal Database Project naïve Bayesian classifier, NBC); and, 3) a phylogeny-based method (Statistical Assignment Package, SAP). We also tested the effects of sequence length, primer choice, and sequence error on classification accuracy and perceived community composition. Using a leave-one-out cross validation approach, results for classifications to the genus rank were as follows: BLAST + MEGAN had the lowest error rate and was particularly robust to sequence error; SAP accuracy was highest when long LSU query sequences were classified; and, NBC runs significantly faster than the other tested methods. All methods performed poorly with the shortest 50–100 bp sequences. Increasing simulated sequence error reduced classification accuracy. Community shifts were detected due to sequence error and primer selection even though there was no change in the underlying community composition. Short read datasets from individual primers, as well as pooled datasets, appear to only approximate the true community composition. We hope this work informs investigators of some of the factors that affect the quality and interpretation of their environmental gene surveys
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