02 September 1944 CHAVES County Specimen Collection Data

Specimen collected 02 September 1944. Original Locality: Bitter Lakes Refuge, Units 15 and 16, Roswell. Locality: Units 15 and 16 Waterfowl Lakes, Bitter Lake National Refuge, Roswell.Catalog number: MSB109; Taxa: Lepomis cyanellus; Common name: green sunfish; Count of specimens: 16; Standard length:Catalog number: MSB185; Taxa: Lepomis macrochirus; Common name: bluegill ; Count of specimens: 2; Standard length:Catalog number: MSB220; Taxa: Micropterus salmoides; Common name: largemouth bass; Count of specimens: 4; Standard length:Catalog number: MSB241; Taxa: Lepomis megalotis; Common name: longear sunfish; Count of specimens: 8; Standard length:Catalog number: MSB562; Taxa: Fundulus zebrinus; Common name: plains killifish; Count of specimens: 61; Standard length:Catalog number: MSB587; Taxa: Lucania parva; Common name: rainwater killifish; Count of specimens: 92; Standard length:Catalog number: MSB1199; Taxa: Notropis stramineus; Common name: sand shiner; Count of specimens: 7; Standard length:Catalog number: MSB1228; Taxa: Notropis stramineus; Common name: sand shiner; Count of specimens: 8; Standard length:Catalog number: MSB1332; Taxa: Cyprinella lutrensis; Common name: red shiner; Count of specimens: 40; Standard length:Catalog number: MSB1368; Taxa: Cyprinella lutrensis; Common name: red shiner; Count of specimens: 15; Standard length:Catalog number: MSB1964; Taxa: Dorosoma cepedianum; Common name: gizzard shad; Count of specimens: 4; Standard length:Catalog number: MSB2190; Taxa: Astyanax mexicanus; Common name: Mexican tetra; Count of specimens: 12; Standard length:Catalog number: MSB2218; Taxa: Dionda episcopa; Common name: roundnose minnow; Count of specimens: 1; Standard length:Catalog number: MSB2954; Taxa: Gambusia affinis; Common name: western mosquitofish; Count of specimens: 160; Standard length:Catalog number: MSB3132; Taxa: Cyprinodon pecosensis; Common name: Pecos pupfish; Count of specimens: 247; Standard length:Catalog number: MSB3133; Taxa: Cyprinodon pecosensis; Common name: Pecos pupfish; Count of specimens: 149; Standard length:Catalog number: MSB3734; Taxa: Gambusia nobilis; Common name: Pecos gambusia; Count of specimens: 22; Standard length

04 September 1944 CHAVES County Specimen Collection Data

Specimen collected 04 September 1944. Original Locality: Pecos R. at Dexter. Locality: Pecos River, at the Dexter bridge or NM County Road 1 crossing ca. 2.0 miles northeast of Dexter.Catalog number: MSB1134; Taxa: Hybognathus amarus; Common name: Rio Grande silvery minnow; Count of specimens: 12; Standard length:Catalog number: MSB1328; Taxa: Cyprinella lutrensis; Common name: red shiner; Count of specimens: 2; Standard length:Catalog number: MSB1860; Taxa: Macrhybopsis aestivalis; Common name: speckled chub; Count of specimens: 3; Standard length:Catalog number: MSB3214; Taxa: Carpiodes carpio; Common name: river carpsucker; Count of specimens: 2; Standard length:Catalog number: MSB3343; Taxa: Lepisosteus osseus; Common name: longnose gar; Count of specimens: 17; Standard length

Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19

BACKGROUND Early treatment to prevent severe coronavirus disease 2019 (Covid-19) is an important component of the comprehensive response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. METHODS In this phase 3, double-blind, randomized, placebo-controlled trial, we used a 2-by-3 factorial design to test the effectiveness of three repurposed drugs - metformin, ivermectin, and fluvoxamine - in preventing serious SARS-CoV-2 infection in nonhospitalized adults who had been enrolled within 3 days after a confirmed diagnosis of infection and less than 7 days after the onset of symptoms. The patients were between the ages of 30 and 85 years, and all had either overweight or obesity. The primary composite end point was hypoxemia (≤93% oxygen saturation on home oximetry), emergency department visit, hospitalization, or death. All analyses used controls who had undergone concurrent randomization and were adjusted for SARSCoV-2 vaccination and receipt of other trial medications. RESULTS A total of 1431 patients underwent randomization; of these patients, 1323 were included in the primary analysis. The median age of the patients was 46 years; 56% were female (6% of whom were pregnant), and 52% had been vaccinated. The adjusted odds ratio for a primary event was 0.84 (95% confidence interval [CI], 0.66 to 1.09; P=0.19) with metformin, 1.05 (95% CI, 0.76 to 1.45; P=0.78) with ivermectin, and 0.94 (95% CI, 0.66 to 1.36; P=0.75) with fluvoxamine. In prespecified secondary analyses, the adjusted odds ratio for emergency department visit, hospitalization, or death was 0.58 (95% CI, 0.35 to 0.94) with metformin, 1.39 (95% CI, 0.72 to 2.69) with ivermectin, and 1.17 (95% CI, 0.57 to 2.40) with fluvoxamine. The adjusted odds ratio for hospitalization or death was 0.47 (95% CI, 0.20 to 1.11) with metformin, 0.73 (95% CI, 0.19 to 2.77) with ivermectin, and 1.11 (95% CI, 0.33 to 3.76) with fluvoxamine. CONCLUSIONS None of the three medications that were evaluated prevented the occurrence of hypoxemia, an emergency department visit, hospitalization, or death associated with Covid-19

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

03 September 1944 CHAVES County Specimen Collection Data

Specimen collected 03 September 1944. Original Locality: Pecos R. 15 mi. NE of Roswell. Locality: Pecos River, 15 miles northeast of Roswell.Catalog number: MSB68; Taxa: Pomoxis annularis; Common name: white crappie; Count of specimens: 1; Standard length:Catalog number: MSB333; Taxa: Gambusia affinis; Common name: western mosquitofish; Count of specimens: 12; Standard length:Catalog number: MSB569; Taxa: Fundulus zebrinus; Common name: plains killifish; Count of specimens: 46; Standard length:Catalog number: MSB664; Taxa: Pimephales promelas; Common name: fathead minnow; Count of specimens: 1; Standard length:Catalog number: MSB1128; Taxa: Hybognathus amarus; Common name: Rio Grande silvery minnow; Count of specimens: 644; Standard length:Catalog number: MSB1344; Taxa: Cyprinella lutrensis; Common name: red shiner; Count of specimens: 115; Standard length:Catalog number: MSB1376; Taxa: Notropis jemezanus; Common name: Rio Grande shiner; Count of specimens: 79; Standard length:Catalog number: MSB1867; Taxa: Macrhybopsis aestivalis; Common name: speckled chub; Count of specimens: 85; Standard length:Catalog number: MSB1978; Taxa: Dorosoma cepedianum; Common name: gizzard shad; Count of specimens: 404; Standard length:Catalog number: MSB2631; Taxa: Notropis simus; Common name: bluntnose shiner; Count of specimens: 818; Standard length:Catalog number: MSB3182; Taxa: Pylodictis olivaris; Common name: flathead catfish; Count of specimens: 1; Standard length:Catalog number: MSB3200; Taxa: Carpiodes carpio; Common name: river carpsucker; Count of specimens: 66; Standard length:Catalog number: MSB3342; Taxa: Lepisosteus osseus; Common name: longnose gar; Count of specimens: 1; Standard length:Catalog number: MSB3443; Taxa: Cyprinodon pecosensis; Common name: Pecos pupfish; Count of specimens: 1; Standard length

02 September 1944 CHAVES County Specimen Collection Data

Specimen collected 02 September 1944. Original Locality: Bitter Lakes Refuge, Units 15 and 16, Roswell. Locality: Units 15 and 16 Waterfowl Lakes, Bitter Lake National Refuge, Roswell.Catalog number: MSB109; Taxa: Lepomis cyanellus; Common name: green sunfish; Count of specimens: 16; Standard length:Catalog number: MSB185; Taxa: Lepomis macrochirus; Common name: bluegill ; Count of specimens: 2; Standard length:Catalog number: MSB220; Taxa: Micropterus salmoides; Common name: largemouth bass; Count of specimens: 4; Standard length:Catalog number: MSB241; Taxa: Lepomis megalotis; Common name: longear sunfish; Count of specimens: 8; Standard length:Catalog number: MSB562; Taxa: Fundulus zebrinus; Common name: plains killifish; Count of specimens: 61; Standard length:Catalog number: MSB587; Taxa: Lucania parva; Common name: rainwater killifish; Count of specimens: 92; Standard length:Catalog number: MSB1199; Taxa: Notropis stramineus; Common name: sand shiner; Count of specimens: 7; Standard length:Catalog number: MSB1228; Taxa: Notropis stramineus; Common name: sand shiner; Count of specimens: 8; Standard length:Catalog number: MSB1332; Taxa: Cyprinella lutrensis; Common name: red shiner; Count of specimens: 40; Standard length:Catalog number: MSB1368; Taxa: Cyprinella lutrensis; Common name: red shiner; Count of specimens: 15; Standard length:Catalog number: MSB1964; Taxa: Dorosoma cepedianum; Common name: gizzard shad; Count of specimens: 4; Standard length:Catalog number: MSB2190; Taxa: Astyanax mexicanus; Common name: Mexican tetra; Count of specimens: 12; Standard length:Catalog number: MSB2218; Taxa: Dionda episcopa; Common name: roundnose minnow; Count of specimens: 1; Standard length:Catalog number: MSB2954; Taxa: Gambusia affinis; Common name: western mosquitofish; Count of specimens: 160; Standard length:Catalog number: MSB3132; Taxa: Cyprinodon pecosensis; Common name: Pecos pupfish; Count of specimens: 247; Standard length:Catalog number: MSB3133; Taxa: Cyprinodon pecosensis; Common name: Pecos pupfish; Count of specimens: 149; Standard length:Catalog number: MSB3734; Taxa: Gambusia nobilis; Common name: Pecos gambusia; Count of specimens: 22; Standard length