4,137 research outputs found
Model for Anisotropic Directed Percolation
We propose a simulation model to study the properties of directed percolation
in two-dimensional (2D) anisotropic random media. The degree of anisotropy in
the model is given by the ratio between the axes of a semi-ellipse
enclosing the bonds that promote percolation in one direction. At percolation,
this simple model shows that the average number of bonds per site in 2D is an
invariant equal to 2.8 independently of . This result suggests that
Sinai's theorem proposed originally for isotropic percolation is also valid for
anisotropic directed percolation problems. The new invariant also yields a
constant fractal dimension for all , which is the same
value found in isotropic directed percolation (i.e., ).Comment: RevTeX, 9 pages, 3 figures. To appear in Phys.Rev.
Finite-Size Scaling in Two-dimensional Continuum Percolation Models
We test the universal finite-size scaling of the cluster mass order parameter
in two-dimensional (2D) isotropic and directed continuum percolation models
below the percolation threshold by computer simulations. We found that the
simulation data in the 2D continuum models obey the same scaling expression of
mass M to sample size L as generally accepted for isotropic lattice problems,
but with a positive sign of the slope in the ln-ln plot of M versus L. Another
interesting aspect of the finite-size 2D models is also suggested by plotting
the normalized mass in 2D continuum and lattice bond percolation models, versus
an effective percolation parameter, independently of the system structure (i.e.
lattice or continuum) and of the possible directions allowed for percolation
(i.e. isotropic or directed) in regions close to the percolation thresholds.
Our study is the first attempt to map the scaling behaviour of the mass for
both lattice and continuum model systems into one curve.Comment: 9 pages, Revtex, 2 PostScript figure
The empirical evaluation of thermal conduction coefficient of some liquid composite heat insulating materials
We experimentally determined the coefficients of thermal conductivity of some ultra thin liquid composite heat insulating coatings, for sample 1 [lambda]=0.086 W/(m [x] C), for sample 2 [lambda]= 0.091 W/(m [x] C). We performed the measurement error calculation. The actual thermal conduction coefficient of the studied samples was higher than the declared one. The manufactures of liquid coatings might have used some "ideal" conditions when defining heat conductivity in the laboratory or the coefficient was obtained by means of theoretical solution of heat conduction problem in liquid composite insulating media. However, liquid insulating coatings are of great interest to builders, because they allow to warm objects of complex geometric shapes (valve chambers, complex assemblies, etc.), which makes them virtually irreplaceable. The proper accounting of heating qualities of paints will allow to avoid heat loss increase above the specified limits in insulated pipes with heat transfer materials or building structures, as well as protect them from possible thawing in the period of subzero weather
Synoptic Sky Surveys and the Diffuse Supernova Neutrino Background: Removing Astrophysical Uncertainties and Revealing Invisible Supernovae
The cumulative (anti)neutrino production from all core-collapse supernovae
within our cosmic horizon gives rise to the diffuse supernova neutrino
background (DSNB), which is on the verge of detectability. The observed flux
depends on supernova physics, but also on the cosmic history of supernova
explosions; currently, the cosmic supernova rate introduces a substantial
(+/-40%) uncertainty, largely through its absolute normalization. However, a
new class of wide-field, repeated-scan (synoptic) optical sky surveys is coming
online, and will map the sky in the time domain with unprecedented depth,
completeness, and dynamic range. We show that these surveys will obtain the
cosmic supernova rate by direct counting, in an unbiased way and with high
statistics, and thus will allow for precise predictions of the DSNB. Upcoming
sky surveys will substantially reduce the uncertainties in the DSNB source
history to an anticipated +/-5% that is dominated by systematics, so that the
observed high-energy flux thus will test supernova neutrino physics. The
portion of the universe (z < 1) accessible to upcoming sky surveys includes the
progenitors of a large fraction (~ 87%) of the expected 10-26 MeV DSNB event
rate. We show that precision determination of the (optically detected) cosmic
supernova history will also make the DSNB into a strong probe of an extra flux
of neutrinos from optically invisible supernovae, which may be unseen either
due to unexpected large dust obscuration in host galaxies, or because some
core-collapse events proceed directly to black hole formation and fail to give
an optical outburst.Comment: 11 pages, 6 figure
The afterglow and kilonova of the short GRB 160821B
GRB 160821B is a short duration gamma-ray burst (GRB) detected and localized
by the Neil Gehrels Swift Observatory in the outskirts of a spiral galaxy at
z=0.1613, at a projected physical offset of 16 kpc from the galaxy's center. We
present X-ray, optical/nIR and radio observations of its counterpart and model
them with two distinct components of emission: a standard afterglow, arising
from the interaction of the relativistic jet with the surrounding medium, and a
kilonova, powered by the radioactive decay of the sub-relativistic ejecta.
Broadband modeling of the afterglow data reveals a weak reverse shock
propagating backward into the jet, and a likely jet-break at 3.5 d. This is
consistent with a structured jet seen slightly off-axis while expanding into a
low-density medium. Analysis of the kilonova properties suggests a rapid
evolution toward red colors, similar to AT2017gfo, and a low nIR luminosity,
possibly due to the presence of a long-lived neutron star. The global
properties of the environment, the inferred low mass (M_ej < 0.006 Msun) and
velocities (v > 0.05 c) of lanthanide-rich ejecta are consistent with a binary
neutron star merger progenitor.Comment: 14 pages, 6 figures, MNRAS, in press. Moderate revision, added Figure
5 and X-ray data to Table
Penetration of hot electrons through a cold disordered wire
We study a penetration of an electron with high energy E<<T through strongly
disordered wire of length L<<a (a being the localization length). Such an
electron can loose, but not gain the energy, when hopping from one localized
state to another. We have found a distribution function for the transmission
coefficient t. The typical t remains exponentially small in L/a, but with the
decrement, reduced compared to the case of direct elastic tunnelling. The
distribution function has a relatively strong tail in the domain of anomalously
high t; the average ~(a/L)^2 is controlled by rare configurations of
disorder, corresponding to this tail.Comment: 4 pages, 5 figure
The empirical definition of total emissivity of modern super-thin liquid composite thermal insulators
Modern world trends in the field of energy and mineral resources preservation policy involves the need for a more cost-efficient use of the Earth's natural resources, including in the field of construction industry. Using insulation modern materials would largely solve this problem. The acceptability appraisal of various advanced heat-insulating blankets is a crucial task, which requires experimental verification of total emissivity empirical definition of modern super-thin liquid composite thermal insulators and their real value definition. Method of investigation is as follows: an empirical definition of blankets emissivity using the proposed laboratory equipment, which comprises a system of "gray" bodies, thermocouple probe and a source of continuous heat flux. Total emissivity of modern super-thin liquid composite thermal insulators is experimentally determined. It amounted e = 0.89 for sample # 1, and e = 0.87 for sample # 2 at a temperature of 35-65 °C. It was found that the actual emissivity of the samples was higher than it had been declared
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CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma.
BackgroundLong non-coding RNAs (lncRNAs) exhibit highly cell type-specific expression and function, making this class of transcript attractive for targeted cancer therapy. However, the vast majority of lncRNAs have not been tested as potential therapeutic targets, particularly in the context of currently used cancer treatments. Malignant glioma is rapidly fatal, and ionizing radiation is part of the current standard-of-care used to slow tumor growth in both adult and pediatric patients.ResultsWe use CRISPR interference (CRISPRi) to screen 5689 lncRNA loci in human glioblastoma (GBM) cells, identifying 467 hits that modify cell growth in the presence of clinically relevant doses of fractionated radiation. Thirty-three of these lncRNA hits sensitize cells to radiation, and based on their expression in adult and pediatric gliomas, nine of these hits are prioritized as lncRNA Glioma Radiation Sensitizers (lncGRS). Knockdown of lncGRS-1, a primate-conserved, nuclear-enriched lncRNA, inhibits the growth and proliferation of primary adult and pediatric glioma cells, but not the viability of normal brain cells. Using human brain organoids comprised of mature neural cell types as a three-dimensional tissue substrate to model the invasive growth of glioma, we find that antisense oligonucleotides targeting lncGRS-1 selectively decrease tumor growth and sensitize glioma cells to radiation therapy.ConclusionsThese studies identify lncGRS-1 as a glioma-specific therapeutic target and establish a generalizable approach to rapidly identify novel therapeutic targets in the vast non-coding genome to enhance radiation therapy
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