Education/Connection/Action: Community Literacies and Shared Knowledges as Creative Productions for Social Justice

This article highlights Education/Connection/Action (ECA), a locally developed community pedagogy deployed at a youth activism summer camp that served as a site for a community/academic teaching and research collaboration. Youth considered connections between a set of issues, including a local ban on Ethnic Studies, the School-to-Prison Pipeline, and Youth Sexuality, Health, and Rights. They drew from lived and learned literacies to inform participatory media projects that critically and creatively address restrictions on access to local knowledges and information with particular relevance to youth sexuality, health, and rights (broadly defined). In highlighting youth voices, desires, and needs across distinct youth communities, their collaborative productions demonstrate coalitional potential and a collective call for change

Transdisciplinary and Community Literacies: Shifting Discourses and Practices through New Paradigms of Public Scholarship and Action- Oriented Research

In 2010, we received a nationally competitive grant from the Ford Foundation to undertake cross-disciplinary, community-engaged work to shift public conversations around youth sexuality, health, and rights (YSHR). We came to the projects from our positions as a humanities scholar (Licona) and as a social science scholar (Russell). According to the Ford Foundation, “a deeper understanding of human sexuality is an essential element of human rights and healthy social relationships.” Beginning with this assumption, we seek to be informed by and to inform policies and local practices; to initiate broad conversations that address sexual health and healthy sexualities for youth; and ultimately to develop innovative collaborations, programs, and research

Characterization of the local productive sector associated with the technology program in systematized accounting: theoretical review.

El crecimiento económico y social de las naciones, responde al desarrollo de competencias de su población y de cómo se integran esas competencias al sector productivo, es por ello que debe ser relevante para los programas técnicos y profesionales desarrollar estudios que permitan la caracterización el sector empresarial, logrando así identificar los requerimientos presentes y las tendencias futuras en relación con los perfiles que deben poseer sus egresados. Esa anticipación impulsa a las instituciones de educación superior y las lleva a ubicarse en los principales lugares a nivel nacional e internacional. A raíz de lo anterior el presente proyecto estudio desde el programa de tecnología en contabilidad sistematizada, tiene como objetivo general caracterizar el sector productivo de Cartagena de Indias con la finalidad de identificar las necesidades o requerimientos relacionados con el perfil del tecnólogo en contabilidad sistematizada. El enfoque implementado en la investigación es de naturaleza cualitativo, en una primera etapa se realiza la revisión documental con el propósito de sentar las bases para la identificación de las variables a considerar en la segunda etapa de recolección y procesamiento de datos. Cabe aclara que los resultados mostrados en el presente documento derivan de la primera fase de la investigación.The economic and social growth of nations responds to the development of competencies of its population and how these competencies are integrated into the productive sector, which is why it should be relevant for technical and professional programs to develop studies that allow the characterization of the business sector, thus identifying the present requirements and future trends in relation to the profiles that their graduates should have. This anticipation drives higher education institutions and leads them to position themselves in the main national and international places. As a result of the above, the general objective of the present study project from the program of technology in systematized accounting is to characterize the productive sector of Cartagena de Indias with the purpose of identifying the needs or requirements related to the profile of the technologist in systematized accounting. The approach implemented in the research is qualitative in nature, in a first stage the documentary review is carried out with the purpose of laying the foundations for the identification of the variables to be considered in the second stage of data collection and processing. It should be clarified that the results shown in this document derive from the first phase of the research

Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation.

BACKGROUND: Macrophages play prominent roles in bacteria recognition and clearance, including Borrelia burgdorferi (Bb), the Lyme disease spirochete. To elucidate mechanisms by which MyD88/TLR signaling enhances clearance of Bb by macrophages, we studied wildtype (WT) and MyD88 RESULTS: MyD88 CONCLUSION: Our findings show that MyD88 signaling enhances, but is not required, for bacterial uptake or phagosomal maturation and provide mechanistic insights into how MyD88-mediated phagosomal signaling enhances Bb uptake and clearance

Mild hypoxic-ischemic encephalopathy (HIE): Timing and pattern of MRI brain injury

BACKGROUND: Mild hypoxic-ischemic encephalopathy (HIE) is increasingly recognized as a risk factor for neonatal brain injury. We examined the timing and pattern of brain injury in mild HIE. METHODS: This retrospective cohort study includes infants with mild HIE treated at 9 hospitals. Neonatal brain MRIs were scored by 2 reviewers using a validated classification system, with discrepancies resolved by consensus. Severity and timing of MRI brain injury (i.e., acute, subacute, chronic) was scored on the subset of MRIs that were performed at or before 8 days of age. RESULTS: Of 142 infants with mild HIE, 87 (61%) had injury on MRI at median age 5 (IQR 4-6) days. Watershed (23%), deep gray (20%) and punctate white matter (18%) injury were most common. Among the 125 (88%) infants who received a brain MRI at ≤8 days, mild (44%) injury was more common than moderate (11%) or severe (4%) injury. Subacute (37%) lesions were more commonly observed than acute (32%) or chronic lesions (1%). CONCLUSION: Subacute brain injury is common in newborn infants with mild HIE. Novel neuroprotective treatments for mild HIE will ideally target both subacute and acute injury mechanisms. IMPACT: Almost two-thirds of infants with mild HIE have evidence of brain injury on MRI obtained in the early neonatal period. Subacute brain injury was seen in 37% of infants with mild HIE. Neuroprotective treatments for mild HIE will ideally target both acute and subacute injury mechanisms

Nut production in Bertholletia excelsa across a logged forest mosaic: implications for multiple forest use

Although many examples of multiple-use forest management may be found in tropical smallholder systems, few studies provide empirical support for the integration of selective timber harvesting with non-timber forest product (NTFP) extraction. Brazil nut (Bertholletia excelsa, Lecythidaceae) is one of the world’s most economically-important NTFP species extracted almost entirely from natural forests across the Amazon Basin. An obligate out-crosser, Brazil nut flowers are pollinated by large-bodied bees, a process resulting in a hard round fruit that takes up to 14 months to mature. As many smallholders turn to the financial security provided by timber, Brazil nut fruits are increasingly being harvested in logged forests. We tested the influence of tree and stand-level covariates (distance to nearest cut stump and local logging intensity) on total nut production at the individual tree level in five recently logged Brazil nut concessions covering about 4000 ha of forest in Madre de Dios, Peru. Our field team accompanied Brazil nut harvesters during the traditional harvest period (January-April 2012 and January-April 2013) in order to collect data on fruit production. Three hundred and ninety-nine (approximately 80%) of the 499 trees included in this study were at least 100 m from the nearest cut stump, suggesting that concessionaires avoid logging near adult Brazil nut trees. Yet even for those trees on the edge of logging gaps, distance to nearest cut stump and local logging intensity did not have a statistically significant influence on Brazil nut production at the applied logging intensities (typically 1–2 timber trees removed per ha). In one concession where at least 4 trees ha-1 were removed, however, the logging intensity covariate resulted in a marginally significant (0.09) P value, highlighting a potential risk for a drop in nut production at higher intensities. While we do not suggest that logging activities should be completely avoided in Brazil nut rich forests, when a buffer zone cannot be observed, low logging intensities should be implemented. The sustainability of this integrated management system will ultimately depend on a complex series of socioeconomic and ecological interactions. Yet we submit that our study provides an important initial step in understanding the compatibility of timber harvesting with a high value NTFP, potentially allowing for diversification of forest use strategies in Amazonian Perù

Gut dysbiosis and clinical phases of pancolitis in patients with ulcerative colitis

Ulcerative colitis (UC) is a frequent type of inflammatory bowel disease, characterized by periods of remission and exacerbation. Gut dysbiosis may influence pathophysiology and clinical response in UC. The purpose of this study was to evaluate whether gut microbiota is related to the active and remission phases of pancolitis in patients with UC as well as in healthy participants. Fecal samples were obtained from 18 patients with UC and clinical‐endoscopic evidenced pancolitis (active phase n = 9 and remission phase n = 9), as well as 15 healthy participants. After fecal DNA extraction, the 16S rRNA gene was amplified and sequenced (Illumina MiSeq), operational taxonomic units were analyzed with the QIIME software. Gut microbiota composition revealed a higher abundance of the phyla Proteobacteria and Fusobacteria in active pancolitis, as compared with remission and healthy participants. Likewise, a marked abundance of the genus Bilophila and Fusobacteria were present in active pancolitis, whereas a higher abundance of Faecalibacterium characterized both remission and healthy participants. LEfSe analysis showed that the genus Roseburia and Faecalibacterium were enriched in remission pancolitis, and genera Bilophila and Fusobacterium were enriched in active pancolitis. The relative abundance of Fecalibacterium and Roseburia showed a higher correlation with fecal calprotectin, while Bilophila and Fusobacterium showed AUCs (area under the curve) of 0.917 and 0.988 for active vs. remission pancolitis. The results of our study highlight the relation of gut dysbiosis with clinically relevant phases of pancolitis in patients with UC. Particularly, Fecalibacterium, Roseburia, Bilophila, and Fusobacterium were identified as genera highly related to the different clinical phases of pancolitis