Healthcare stakeholders' perspective on barriers to integrated care in Switzerland: Results from the open-ended question of a nationwide survey.

We aimed to identify the main barriers to integrated care (IC) as reported by healthcare stakeholders from various linguistic regions and health system specificities, according to their reality of practice. Information was gathered through an open-ended question from a national survey conducted in Switzerland in 2019. Responses were analysed qualitatively with the IRaMuTeQ software. Answers from 410 respondents were obtained. Respondents reported barriers at two levels: the system and professional level. Threat to financial benefits, concerns for patient data sharing and tensions between quality of care and benefits for patients versus costs were mentioned at the professional level, in their activity and in patient care. At the system level, limitations at the political level due to federalism and the lack of support and training for professionals were important barriers, in addition to the lack of recognition and compensation for professionals and the fragmented functioning of the health care system. Our study underlines the importance of implementing innovative funding strategies and reimbursement schemes, as well as political willingness to move towards IC. The alignment between federal policies and cantonal specificities also appears as necessary to achieve involvement of professionals, promote integration of services and coordination of professionals for continuous and efficient care

The long delayed solution of the Bukhvostov Lipatov model

In this paper I complete the solution of the Bukhvostov Lipatov model by computing the physical excitations and their factorized S matrix. I also explain the paradoxes which led in recent years to the suspicion that the model may not be integrable.Comment: 9 page

Computer-assisted textual analysis of free-text comments in the Swiss Cancer Patient Experiences (SCAPE) survey.

Patient experience surveys are increasingly conducted in cancer care as they provide important results to consider in future development of cancer care and health policymaking. These surveys usually include closed-ended questions (patient-reported experience measures (PREMs)) and space for free-text comments, but published results are mostly based on PREMs. We aimed to identify the underlying themes of patients' experiences as shared in their own words in the Swiss Cancer Patient Experiences (SCAPE) survey and compare these themes with those assessed with PREMs to investigate how the textual analysis of free-text comments contributes to the understanding of patients' experiences of care. SCAPE is a multicenter cross-sectional survey that was conducted between October 2018 and March 2019 in French-speaking parts of Switzerland. Patients were invited to rate their care in 65 closed-ended questions (PREMs) and to add free-text comments regarding their cancer-related experiences at the end of the survey. We conducted computer-assisted textual analysis using the IRaMuTeQ software on the comments provided by 31% (n = 844) of SCAPE survey respondents (n = 2755). We identified five main thematic classes, two of which consisting of a detailed description of 'cancer care pathways'. The remaining three classes were related to 'medical care', 'gratitude and praise', and the way patients lived with cancer ('cancer and me'). Further analysis of this last class showed that patients' comments related to the following themes: 'initial shock', 'loneliness', 'understanding and acceptance', 'cancer repercussions', and 'information and communication'. While closed-ended questions related mainly to factual aspects of experiences of care, free-text comments related primarily to the personal and emotional experiences and consequences of having cancer and receiving care. A computer-assisted textual analysis of free-text in our patient survey allowed a time-efficient classification of free-text data that provided insights on the personal experience of living with cancer and additional information on patient experiences that had not been collected with the closed-ended questions, underlining the importance of offering space for comments. Such results can be useful to inform questionnaire development, provide feedback to professional teams, and guide patient-centered initiatives to improve the quality and safety of cancer care

Effects of light and intraspecific competition on growth and crown morphology of two size classes of understory balsam fir saplings

This paper characterizes the growth and crown morphology of young balsam fir saplings naturally regenerated under a gradient of understory light environments and intraspecific competition densities for two size classes (50-100 cm and 100-200 cm). Most growth and crown morphological parameters investigated were strongly related to the natural light gradient investigated (3-83% full sunlight), but the relationship tended to plateau at around 25% full sunlight. The relationships were generally better for the larger size class. Intraspecific competition did not significantly affect growth and crown morphology of saplings receiving less than 25% full sunlight, but it affected relative height growth, relative radial growth and the apical dominance ratio for those receiving more than 25% full sunlight (R2=0.506; p<0.001; R2=0.403; p<0.002; R2=0.348; p<0.001, respectively). These results suggest that live crown ratio, apical dominance ratio and the number of internodal branches can provide, alone or in combination, useful indicators of vigour for understory fir. Such a study provides the basic data inputs required for the development of empirically-derived mechanistic models that can predict understory tree growth and survival

Boundary interactions changing operators and dynamical correlations in quantum impurity problems

Recent developments have made possible the computation of equilibrium dynamical correlators in quantum impurity problems. In many situations however, one is rather interested in correlators subject to a non equilibrium initial preparation; this is the case for instance for the occupation probability $P(t)$ in the double well problem of dissipative quantum mechanics (DQM). We show in this paper how to handle this situation in the framework of integrable quantum field theories by introducing ``boundary interactions changing operators''. We determine the properties of these operators by using an axiomatic approach similar in spirit to what is done for form-factors. This allows us to obtain new exact results for $P(t)$; for instance, we find that that at large times (or small $g$), the leading behaviour for g < 1/2} is $P(t)\propto e^{-\Gamma t}\cos\Omega t$, with the universal ratio. $\Omega/\Gamma = \cot {\pi g}/{2(1-g)}$.Comment: 4 pages, revte

Exact Friedel oscillations in the g=1/2 Luttinger liquid

A single impurity in the 1D Luttinger model creates a local modification of the charge density analogous to the Friedel oscillations. In this paper, we present an exact solution of the case $g={1\over 2}$ (the equivalent of the Toulouse point) at any temperature $T$ and impurity coupling, expressing the charge density in terms of a hypergeometric function. We find in particular that at $T=0$, the oscillatory part of the density goes as $\ln x$ at small distance and $x^{-1/2}$ at large distance.Comment: 1 reference added. 13 pages, harvma

Moment tensor inversion of Explosive Long Period events recorded on Arenal Volcano, Costa Rica, constrained by synthetic tests

International audienceIn order to constrain the moment tensor solution of an explosive seismic event recorded on Arenal volcano, Costa Rica, we perform tests using synthetic data. These data are generated using a 3D model including the topography of the volcano and the best estimation of the velocity model available for Arenal. Solutions for (i) the moment tensor components, and (ii) the moment tensor plus single forces, are analyzed. When noisy data and mislocated sources are used in the inversion, spurious single forces are easily generated in the solution for the moment tensor components plus single forces. Forces also appear when the inversion is performed using an explosive event recorded on Arenal in 2005. Synthetic tests indicate that these forces might be spurious. However the mechanism is correctly retrieved by the inversion in both solutions. The ability to recover the explosive mechanism for the 2005 event combined with the interpretative aids from the synthetics tests will enable us to invert for the large variation in events observed on Arenal

Transfer of recessive skr crossability trait into well-adapted French wheat cultivar Barok through marker-assisted backcrossing method

In order to increase genetic diversity in cereals, interspecific or even intergeneric crosses are worthwhile, especially wheat by rye crosses for triticale production. However, these crosses often fail due to inhibiting genes. To overcome this obstacle, crossability trait, present in a few wheat cultivars, can be transferred into other wheat lines of agronomical interest. Nevertheless, this transfer remains tedious through conventional backcrossing methods because it is a recessive trait, which requires selfing generations and complex evaluation by many crosses. Here, we present a marker-assisted backcrossing method to transfer this trait more quickly and easily. We chose to introduce the recessive crossability skr, located on chromosome 5BS and originating from Asian wheat, into Barok, a non-crossable French wheat cultivar, with good agronomic characteristics. Six molecular markers, close to the Skr locus, were used to check the transfer of the gene at each of the three backcrosses, without selfing generation nor crosses with rye. Finally, we crossed the predicted crossable lines with rye to validate their crossability. We obtained sixteen lines, morphologically similar to Barok, exhibiting high crossability rate (30%). The markers were thus efficient to transfer the skr crossability but they remain too far from the Skr locus to be considered as diagnostic markers. Indeed, genotyping and phenotyping on other wheat cultivars showed some discrepancies. Nevertheless, this opens the way to enhance genetic diversity more easily and to improve traits of agronomic interest in triticale or wheat as well as to study further barriers to intergeneric crosses

Data calibration for the MASCARA and bRing instruments

Aims: MASCARA and bRing are photometric surveys designed to detect variability caused by exoplanets in stars with $m_V < 8.4$. Such variability signals are typically small and require an accurate calibration algorithm, tailored to the survey, in order to be detected. This paper presents the methods developed to calibrate the raw photometry of the MASCARA and bRing stations and characterizes the performance of the methods and instruments. Methods: For the primary calibration a modified version of the coarse decorrelation algorithm is used, which corrects for the extinction due to the earth's atmosphere, the camera transmission, and intrapixel variations. Residual trends are removed from the light curves of individual stars using empirical secondary calibration methods. In order to optimize these methods, as well as characterize the performance of the instruments, transit signals were injected in the data. Results: After optimal calibration an RMS scatter of 10 mmag at $m_V \sim 7.5$ is achieved in the light curves. By injecting transit signals with periods between one and five days in the MASCARA data obtained by the La Palma station over the course of one year, we demonstrate that MASCARA La Palma is able to recover 84.0, 60.5 and 20.7% of signals with depths of 2, 1 and 0.5% respectively, with a strong dependency on the observed declination, recovering 65.4% of all transit signals at $\delta > 0^\circ$ versus 35.8% at $\delta < 0^\circ$. Using the full three years of data obtained by MASCARA La Palma to date, similar recovery rates are extended to periods up to ten days. We derive a preliminary occurrence rate for hot Jupiters around A-stars of ${>} 0.4 \%$, knowing that many hot Jupiters are still overlooked. In the era of TESS, MASCARA and bRing will provide an interesting synergy for finding long-period (${>} 13.5$ days) transiting gas-giant planets around the brightest stars.Comment: 18 pages, 17 figures, accepted for publication in A&

Tunneling in quantum wires I: Exact solution of the spin isotropic case

We show that the problem of impurity tunneling in a Luttinger liquid of electrons with spin is solvable in the spin isotropic case ($g_\sigma=2$, $g_\rho$ arbitrary). The resulting integrable model is similar to a two channel anisotropic Kondo model, but with the impurity spin in a "cyclic representation" of the quantum algebra $su(2)_q$ associated with the anisotropy. Using exact, non-perturbative techniques we study the RG flow, and compute the DC conductance. As expected from the analysis of Kane and Fisher we find that the IR fixed point corresponds to two separate leads. We also prove an exact duality between the UV and IR expansions of the current at vanishing temperature.Comment: Revtex, epsf, 14pgs, 4 figs. One reference adde