O perfil de potenciais doadores de órgãos e tecidos

This study aimed to characterize donors according to gender, age group, cause of brain death; quantify donors with hypernatremia, hyperpotassemia and hypopotassemia; and get to know which organs were the most used in transplantations. This quantitative, descriptive, exploratory and retrospective study was performed at the Organ Procurement Organization of the University of São Paulo Medical School Hospital das Clínicas. Data from the medical records of 187 potential donors were analyzed. Cerebrovascular accidents represented 53.48% of all brain death causes, sodium and potassium disorders occurred in 82.36% of cases and 45.46% of the potential donors were between 41 and 60 years old. The results evidenced that natural death causes exceeded traumatic deaths, and that most donors presented sodium and potassium alterations, likely associated to inappropriate maintenance.Se tuvo como objetivos determinar las características de los donadores según el sexo, el intervalo de edad, y, las causas por muerte encefálica; determinar el número donadores que presentaban hipernatremia, hiperpotasemia y hipopotasemia; conocer los órganos que fueron más utilizados para el trasplante. Es un estudio de tipo cuantitativo, descriptivo, exploratorio y retrospectivo. La investigación fue realizada en una Institución de donación de Órganos perteneciente al Hospital de las Clínicas de Sao Paulo. Fueron analizados los datos de 187 probables donadores. Entre las causas de muerte encefálica el 53,48% fueron por accidente cerebro vascular, en 82,36% de los casos se produjeron alteraciones en los valores de sodio y potasio y los donadores se encontraban entre 41 y 60 años de edad. Los resultados muestran que las causas naturales de muerte superaron a las muertes por traumatismo. La mayoría de los donadores tuvo alteraciones en los niveles de sodio y potasio, estando posiblemente relacionadas a medidas de conservación inadecuadas.Objetivou-se caracterizar os doadores, segundo o sexo, faixa etária, causa de morte encefálica, quantificar os doadores que apresentaram hipernatremia, hiperpotassemia e hipopotassemia e conhecer quais os órgãos mais utilizados para transplante. Trata-se de estudo de caráter quantitativo, descritivo, exploratório e retrospectivo. A pesquisa foi realizada na Organização de Procura de Órgãos do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. Foram analisados os dados dos prontuários de 187 potenciais doadores. O acidente vascular cerebral representou 53,48% de todas as causas de morte encefálica, os distúrbios de sódio e potássio ocorreram em 82,36% dos casos e 45,46% dos potenciais doadores tinham de 41 a 60 anos. Os resultados obtidos evidenciaram que as causas naturais de morte superaram as mortes traumáticas e a maioria dos doadores apresentou alterações de sódio e potássio provavelmente relacionadas à manutenção inadequada

El perfil de probables donadores de órganos y tejidos

Objetivou-se caracterizar os doadores, segundo o sexo, faixa etária, causa de morte encefálica, quantificar os doadores que apresentaram hipernatremia, hiperpotassemia e hipopotassemia e conhecer quais os órgãos mais utilizados para transplante. Trata-se de estudo de caráter quantitativo, descritivo, exploratório e retrospectivo. A pesquisa foi realizada na Organização de Procura de Órgãos do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. Foram analisados os dados dos prontuários de 187 potenciais doadores. O acidente vascular cerebral representou 53,48% de todas as causas de morte encefálica, os distúrbios de sódio e potássio ocorreram em 82,36% dos casos e 45,46% dos potenciais doadores tinham de 41 a 60 anos. Os resultados obtidos evidenciaram que as causas naturais de morte superaram as mortes traumáticas e a maioria dos doadores apresentou alterações de sódio e potássio provavelmente relacionadas à manutenção inadequada.Se tuvo como objetivos determinar las características de los donadores según el sexo, el intervalo de edad, y, las causas por muerte encefálica; determinar el número donadores que presentaban hipernatremia, hiperpotasemia y hipopotasemia; conocer los órganos que fueron más utilizados para el trasplante. Es un estudio de tipo cuantitativo, descriptivo, exploratorio y retrospectivo. La investigación fue realizada en una Institución de donación de Órganos perteneciente al Hospital de las Clínicas de Sao Paulo. Fueron analizados los datos de 187 probables donadores. Entre las causas de muerte encefálica el 53,48% fueron por accidente cerebro vascular, en 82,36% de los casos se produjeron alteraciones en los valores de sodio y potasio y los donadores se encontraban entre 41 y 60 años de edad. Los resultados muestran que las causas naturales de muerte superaron a las muertes por traumatismo. La mayoría de los donadores tuvo alteraciones en los niveles de sodio y potasio, estando posiblemente relacionadas a medidas de conservación inadecuadas.This study aimed to characterize donors according to gender, age group, cause of brain death; quantify donors with hypernatremia, hyperpotassemia and hypopotassemia; and get to know which organs were the most used in transplantations. This quantitative, descriptive, exploratory and retrospective study was performed at the Organ Procurement Organization of the University of São Paulo Medical School Hospital das Clínicas. Data from the medical records of 187 potential donors were analyzed. Cerebrovascular accidents represented 53.48% of all brain death causes, sodium and potassium disorders occurred in 82.36% of cases and 45.46% of the potential donors were between 41 and 60 years old. The results evidenced that natural death causes exceeded traumatic deaths, and that most donors presented sodium and potassium alterations, likely associated to inappropriate maintenance

Morphometry of crossbred nellore claw in differents farm systems

Foram avaliadas morfometricamente, com auxílio de paquímetro eletrônico (Starrett® 799), as dimensões da parede, sola e bulbo do casco dos dedos III e IV dos membros pélvicos e torácicos, direito e esquerdo, de bovinos nelorados machos (Grupo I-confinados) e fêmeas (Grupo II-extensiva). A avaliação estatística dos dados das medidas externas do Grupo I revelou que nenhum dos parâmetros apresentou diferença estatisticamente significativa. O tratamento estatístico das medidas externas do Grupo II mostrou diferença significativa na espessura da parede dos cascos dos dedos III (MTE3) e IV (MTE4) do membro torácico esquerdo, na largura da sola dos cascos dos dedos III (MPD3 e MPE3) e IV (MPD4 e MPE4) dos membros pélvicos direito e esquerdo e na espessura do bulbo dos cascos dos dedos III (MPE3) e IV (MPE4) do membro pélvico esquerdo. _________________________________________________________________________________ ABSTRACTIt has been evaluated morphometrically, with the aid of eletronic caliper (Starrett® 799) the dimensions of the wall, sole and bulb claw; III and IV digits of the pelvic and thoracic, right and left feet of crossbred nellore male (Group I) and female (Group II). The statistical analysis of external data from group I found that none of the parameters demonstrate a statistical difference. The statistical analysis of external measure of group II demonstrated a significant difference in the thickness of the claw wall thickness of digit III (LFL3) and (LFL4) from left forelimb, width of the sole of the digit III (RHL3 and LHL3) and IV (RHL4 and LHL4) of the right and left hindlimb, and thickness of the bulb of digit III (LHL3) and (LHL4) of left hindlimb from group II animals

Effect of clinical treatment of a long distance runner presenting exercise-induced bronchoespasm: a case report

O broncoespasmo induzido pelo exercício (BIE) é uma condição que se caracteriza pelo estreitamento transitório das vias aéreas durante ou após o esforço físico e afeta principalmente portadores de asma. Em atletas profissionais que praticam esportes de alta intensidade, a prevalência também é alta; no entanto, seu diagnóstico permanece subestimado. O presente estudo descreve o caso de um atleta do sexo masculino, 23 anos, corredor de longa distância sem histórico de asma, que após um teste gradual de exercício apresentou chiado no peito e queda da função pulmonar. Após um teste específico, o atleta foi diagnosticado como BIE positivo. Iniciou-se, então, um tratamento clínico com broncodilatador e após 30 dias verificou-se melhora importante em seu consumo máximo de oxigênio, obtido no pico do esforço (VO2 pico).Exercise induced bronchoconstriction (EIB) is characterized by a transient airway constriction during or after vigorous physical activity. This clinical condition is more prevalent in asthmatic patients. The prevalence of EIB in competitive athletes is high; however, EIB is under-diagnosed in this specific athlete population. The present study described a case report of a male 23 year-old long distance runner who, despite not presenting previous asthma history, presented chest squeak and decline on spirometric performance after a cardiopulmonary exercise testing. After specific testing, the athlete was diagnosed as positive EIB. A clinical treatment with bronchodilator was then initiated and after 30 days an important increase in his oxygen uptake peak (VO2peak) was observed

Propostas para revisão dos critérios clínicos de morte encefálica

Atualmente, quase 70 mil pessoas aguardam doação de órgãos no Brasil. O Hospital das Clínicas da Universidade de São Paulo – HCFMUSP é referência em transplantes de órgãos e tecidos e, ao mesmo tempo que se realizam cirurgias de alta complexidade, capacita os profissionais de saúde, sendo um facilitador para a integração dos mesmos. A morte encefálica hoje deve ser considerada uma emergência médica, pois pode salvar várias vidas. O seu diagnóstico é realizado de acordo com a Resolução do Conselho Federal de Medicina nº 1.480/97 e, baseado nessa resolução e em nossa experiência com todo o processo de captação até o transplante, apresentamos neste artigo propostas para evitar a perda de potenciais doadores.Almost 70 thousand people await donation of organs in Brazil. The Hospital das Clínicas of the University of São Paulo is reference center in transplants of organs and woven and, at the same time that you/they take place surgeries of high complexity, it qualifies the professionals of health, being a facilitator for the integration of the same ones. Brain death today should be considered a medical emergency, because its diagnosis can save several lives. Its diagnosis is accomplished in agreement with the Brazilian Medicine Federal Council number 1.480/97 and, based on that resolution and in our experience with whole transplant process, we presented in this paper proposed to avoid the potentials donors’ loss

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic