Registration of Ilani and Oda Durum Wheat Varieties for Highlands of Bale

Two durum wheat (Triticum durum desf.) varieties: Ilani (DZ 2234) and Oda (DZ 2227) developed by Sinana Agricultural Research Centers were released for production in highlands of Bale similar agro ecologies. These varieties were selected and evaluated at Sinana on-station and three onfarms in highlands of Bale for three consecutive years and they were proved to have stable, high yield and superior industrial qualities. They were also proved to have resistance to stem, yellow and leaf rusts. Multilocation testing in the regional variety trial confirmed their productivity with above-average yield performance in all environments and demonstrated their yield stability compared to the commercial durum wheat cultivars Foka, Cocorit-71 and Ingiliz. East African Journal of Sciences Vol. 1 (1) 2007: pp. 88-8

The role of ICT on agricultural knowledge management in Ethiopia: a case study on Woreda knowledge centers in Bure, Goma, Alaba and Alamata

This Study analysed the perspective that information technology can play a central role in knowledge management processes and its challenges and opportunities in the context of Ethiopian infrastructure in the cases under study. It was undertaken in four regions of Ethiopia taking one Woreda Knowledge Centre (WKC) from each region based on purposive sampling method. The study was aimed to assess the role of ICT in IPMSs’ projects of ICT-based Woreda Knowledge Centers (WKC) to investigate if such centers can exploit the opportunity of the ICT-based WKCs for the purpose of enhancing effectiveness of the users. The respondents are the staffs of WOoARD who are using the knowledge centers. Both qualitative and quantitative data were used to obtain reliable information from primary and secondary sources. Data is analysed more qualitatively and also done using descriptive statistics, Percentage and Ranking. The study indicated that the role of ICT in the WKCS is moderate. Due to lack of computer basic skills, shortage of ICT tools and others, there are many challenges that have to be given solutions. The study recommended the way these challenges can be solved. The study also revealed that, the inefficiency of Ethiopian Telecommunication is becoming the obstacle for the process of Knowledge Management (KM) by hindering that there is very poor network connection in all regions so that it is difficult to get and/or disseminate the agricultural information and knowledge by the agricultural service providers

Pre-clinical Models for Studying the Interaction between Mesenchymal Stromal Cells and Cancer Cells and the Induction of Stemness

Mesenchymal stromal cells (MSC) have essential functions in building and supporting the tumour microenvironment, providing metastatic niches, and maintaining cancer hallmarks, and it is increasingly evident that the study of the role of MSC in cancer is crucial for paving the way to clinical opportunities for novel anti-cancer therapies. To date, the vast majority of preclinical models that have been used for studying the effect of reactive MSC on cancer growth, metastasis, and response to therapy has been mainly based on in vitro flat biology, including the co-culturing with cell compartmentalization or with cell-to-cell contact, and on in vivo cancer models with different routes of MSC inoculation. More complex in vitro 3D models based on spheroid structures that are formed by intermingled MSC and tumour cells are also capturing the interest in cancer research. These are innovative culture systems tailored on the specific tumour type and that can be combined with a synthetic extracellular matrix, or included in in silico technologies, to more properly mimic the in vivo biological, spatial, biochemical, and biophysical features of tumour tissues. In this review, we summarized the most popular and currently available preclinical models for evaluating the role of MSC in cancer and their specific suitability, for example, in assaying the MSC-driven induction of epithelial-to-mesenchymal transition or of stem-like traits in cancer cells. Finally, we enlightened the need to carefully consider those parameters that might unintentionally strongly affect the secretome in MSC-cancer interplay and introduce confounding variables for the interpretation of results

A Context Aware Approach for Promoting Tourism Events: The Case of Artist's Lights in Salerno

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Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions

Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication. Neutrophils are highly versatile cells, which play a crucial role in the induction as well as the resolution of inflammation, the control of pathogen replication and the regulation of immune responses. Neutrophil functions have been investigated in human cutaneous leishmaniasis, however, their role in human visceral leishmaniasis is poorly understood. In the present study we evaluated the activation status and effector functions of neutrophils in patients with active VL and after successful anti-leishmanial treatment. Our results show that neutrophils are highly activated and have degranulated; high levels of arginase, myeloperoxidase and elastase, all contained in neutrophils’ granules, were found in the plasma of VL patients. In addition, we show that a large proportion of these cells are immature. We also analysed effector functions of neutrophils that are essential for pathogen clearance and show that neutrophils have an impaired capacity to release neutrophil extracellular traps, produce reactive oxygen species and phagocytose bacterial particles, but not Leishmania parasites. Our results suggest that impaired effector functions, increased activation and immaturity of neutrophils play a key role in the pathogenesis of VL

The influence of molecular mobility on the properties of networks of gold nanoparticles and organic ligands

We prepare and investigate two-dimensional (2D) single-layer arrays and multilayered networks of gold nanoparticles derivatized with conjugated hetero-aromatic molecules, i.e., S-(4-{[2,6-bipyrazol-1-yl)pyrid-4-yl]ethynyl}phenyl)thiolate (herein S-BPP), as capping ligands. These structures are fabricated by a combination of self-assembly and microcontact printing techniques, and are characterized by electron microscopy, UV–visible spectroscopy and Raman spectroscopy. Selective binding of the S-BPP molecules to the gold nanoparticles through Au–S bonds is found, with no evidence for the formation of N–Au bonds between the pyridine or pyrazole groups of BPP and the gold surface. Subtle, but significant shifts with temperature of specific Raman S-BPP modes are also observed. We attribute these to dynamic changes in the orientation and/or increased mobility of the molecules on the gold nanoparticle facets. As for their conductance, the temperature-dependence for S-BPP networks differs significantly from standard alkanethiol-capped networks, especially above 220 K. Relating the latter two observations, we propose that dynamic changes in the molecular layers effectively lower the molecular tunnel barrier for BPP-based arrays at higher temperatures

Well-being in 15-year-old adolescents: a matter of relationship with school

Background Psychosomatic health complaints are significant indicators of adolescent well-being. The aim of this study is to describe the full set of interactions between health complaints and the presence of subjective resources, represented by the quality of relationships with parents and peers and by a positive school perception, in a population of 15-year-old adolescents. Smoking and alcohol consumption were also included in the analyses. Methods Bayesian networks were built for males and females separately, in order to understand the interactions among all considered variables in a representative sample of 16 018 Italian adolescents participating in the Health Behaviour in School-Aged Children survey 2009–10. Results The resulting networks show that school is the crucial node linking adolescents’ well-being with parents and peer relationships, as well as with smoking and alcohol consumption. Conclusions Adolescents' well-being, as well as the prevalence of typical risk behaviours, such as smoking and alcohol consumption, is mediated by the adolescents' academic stress. Therefore, public health interventions, to be effective, should consider addressing the school environment by making it a more inclusive environment promoting critical thinking and sense of belonging rather than just focusing on personal behaviours

Low referral completion of rapid diagnostic test-negative patients in community-based treatment of malaria in Sierra Leone

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