3 research outputs found
An in vitro study of the antioxidant activities and effect on human DNA of the Chinese herbal decoction âliu wei di huangâ
A Chinese medicinal formulation, âLiu Wei Di Huangâ, and its individual components have been tested for the genoprotective effect on human DNA by the comet assay. Results showed no DNA protection contributed by this prescription. However, the aqueous extracts of individual herbs, namely Cortex Moutan and Rhizoma Dioscoreae, were able to decrease by 10â15% the DNA stand break from hydrogen peroxide-mediated oxidative stress. This provides insight to further evaluate the interaction among herbs and the search for the active ingredient responsible for the DNA protective effect